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      • KCI등재

        월성 원자력발전소 주변 해양생물중의 조직결합 삼중수소 농도

        김도성,박규준,임수경,,강희동,도시홍,창규,Kim, Do-Sung,Park, Gyu-Jun,Lin, Xiu-Jing,Kim, Wan,Kang, Hee-Dong,Doh, Sih-Hong,Kim, Chang-Kyu 대한방사선방어학회 2003 방사선방어학회지 Vol.28 No.1

        월성 원자력발전소 주변의 해양생물(해조류와 패류) 시료를 채취하여 조직결합 삼중수소 (OBT) 방사능농도를 측정 분석하였다. 해조류의 OBT 방사능농도는 $0.372{\sim}2.72$ Bq/kg-fresh의 범위였으며, 패류의 OBT 방사능농도는 $0.239{\sim}2.02$ Bq/kg-fresh의 범위였다. 그리고 해조류의 OBT에 의한 내부피폭선량은 $3.4{\times}10^{-7}mSv/year$로 평가되었다. The organically bound tritium(OBT) concentrations of the marine organisms(seaweed and shellfish) around Wolsung nuclear power plants were measured. The OBT concentrations of seaweeds were in the range of $0.372{\sim}2.72$ Bq/kg-fresh. The OBT concentrations of shellfish were in the range of $0.239{\sim}2.02$ Bq/kg-fresh. The internal dose due to the OBT concentration of seaweed was estimated as $3.4{\times}10^{-7}$ mSv/year.

      • KCI등재

        멸종위기종 붉은점모시나비의 서식지 복원구상

        김도성,박성준,신영규,박두상,Kim, Do-Sung,Park, Seong-Joon,Shin, Young-Kyu,Park, Doo-Sang 한국조경학회 2011 韓國造景學會誌 Vol.39 No.6

        나비서식지 복원구상은 종 보전을 위한 중요한 요인의 하나로, 나비의 생태, 서식지 경관, 작업방법, 비용분석 등에 대한 검토를 필요로 한다. 본 연구는 멸종위기종 붉은점모시나비의 서식지 복원을 위하여 요구되는 인자들을 지난 3년간 수행된 연구결과의 검토 및 나비의 성충과 유충의 존재 또는 부재를 조사하는 방법을 통하여 서식지 면적 추정 등의 방식으로 서식지 요건을 분석하였다. 그 결과 국내에서 발견된 붉은점모시나비의 서식지는 유충과 성충이 관찰되는 패치를 기준으로 최소 $300m^2$이상의 크기로 다수의 패치가 필요한 것으로 판단되었다. 따라서 붉은점모시나비 서식지 디자인에서는 기존의 서식지 환경과 유사한 곳에 5개 이상의 패치에 먹이식물과 흡밀식물이 계획되어야 한다. 그리고 나비의 이주를 활발하게 하기 위하여 이주에 방해되는 수목의 제거, 패치간 거리의 최소화, 그리고 징검다리 패치의 추가가 필요하다. 패치연결성 분석결과, 패치간의 거리가 약 600m 이상 떨어질 경우 성공적인 이주가 어려우므로, 각 패치간의 거리는 300m이내에 분포하도록 하는 것이 적절하며, 서식지 크기는 단일 패치에서는 $10,000m^2$이상, 다수의 패치 네트워크에서는 5개 이상의 패치가 인접하고, 각각의 패치는 $1,600m^2$이상으로 전체 패치면적은 $8,000m^2$이상이 필요할 것으로 추정된다. 또한, 단일 서식지보다는 다수의 패치가 인접하여 네트워크를 형성하는 것이 서식지 순환 발생패턴에서 바람직한 것으로 나타났다. 이 연구는 나비의 서식지 복원에 관한 적정한 서식지 요건을 제시하고자 하였으며, 앞으로 진행될 생물종의 복원에 있어서 모델이 될 것으로 기대한다. Habitat restoration initiative is an important factor for the on-site preservation of butterflies. A new habitat necessitates the investigation of the ecology of the butterfly, the landscape of the habitat, the work process, and a cost analysis. In this study, these factors were analyzed through1) re-consideration of the secured results from three years of field work, and 2) a habitat area estimation conducted according to the presence or absence of larvae and adults via a Parnassius bremeri Bremer survey. The investigation of the natural habitat, done for both larvae and adult butterflies found in South Korea, suggested that multiple patches with a minimum size exceeding $300m^2$ and with an average size of about $1,600m^2$were required for survival of this butterfly. Therefore, more than five patches should be considered for butterfly habitat and patches should have similarity to the present habitat environment with transplantation plans for diet plants and honeydew plants. In addition, to activate the migration of the butterfly, cutting down trees that are obstacles to migration, minimizing the distance between patches and the addition of a stepping patch are also required. A patch connectivity analysis showed that patches should be located within 300m of neighboring patches, as the migration of the butterfly will fail if it is more than 600m. Additionally, more than $10,000m^2$ for a single patch or a patch network composed more than five patches over $1,600m^2$ in size were recommended, with a total patch size of $8,000m^2$. Additionally, neighboring multiple patch networks are more desirable than a single habitat in the event a cyclic habitat pattern arises. In this study, we suggest a habitat restoration and optimal prerequisites for a butterfly habitat. It is expected that this research will lead to the creation of a good model for the restoration of butterfly species.

      • KCI등재

        뇌졸중 환자의 자율신경계 기능의 전기생리학적 특성

        김도성,심영주,전포성,이지형,정호중 대한재활의학회 2009 Annals of Rehabilitation Medicine Vol.33 No.6

        Objective: To evaluate the autonomic nervous function in post-stroke patients. Method: A total of 58 subjects, 34 post-stroke patients (mean age of 61.35 years) and 24 healthy subjects (mean age of 34.42 years) were included. The sympathetic skin response (SSR), the R-R interval variation (RRIV) and orthostatic hypotension (OH) were evaluated. Bilateral sympathetic skin responses were recorded on the palm and sole with stimulation of both median and tibial nerves. The obtained SSRs were divided into normal response and abnormal response including no response. The R-R interval variations were estimated during rest, deep breathing and Valsalva maneuver respectively. Results: In all healthy subjects, obtained SSRs were of normal response. Although the rate of abnormal SSR was 75.4% (205 of 272 waves) in stroke patients, the rate of abnormal SSR on affected side (81.6%, 111 of 136 waves) was significantly higher than unaffected side (69.1%, 94 of 136 waves) (p<0.05). The rate of abnormal SSR according to OH was not significantly different (with OH 75.0%, without OH 75.6%) (p>0.05). The RRIV of stroke patients with OH (1.09±0.06) was significantly lower than in control (1.14±0.05) during rest (p<0.01), and in stroke patients without OH, the RRIV (1.13±0.06) was also significantly lower than in control (1.27±0.22) during Valsalva maneuver (p<0.01). Conclusion: Evaluation of SSR and RRIV could be helpful in detecting dysfunction of autonomic nervous system in post-stroke patients. Objective: To evaluate the autonomic nervous function in post-stroke patients. Method: A total of 58 subjects, 34 post-stroke patients (mean age of 61.35 years) and 24 healthy subjects (mean age of 34.42 years) were included. The sympathetic skin response (SSR), the R-R interval variation (RRIV) and orthostatic hypotension (OH) were evaluated. Bilateral sympathetic skin responses were recorded on the palm and sole with stimulation of both median and tibial nerves. The obtained SSRs were divided into normal response and abnormal response including no response. The R-R interval variations were estimated during rest, deep breathing and Valsalva maneuver respectively. Results: In all healthy subjects, obtained SSRs were of normal response. Although the rate of abnormal SSR was 75.4% (205 of 272 waves) in stroke patients, the rate of abnormal SSR on affected side (81.6%, 111 of 136 waves) was significantly higher than unaffected side (69.1%, 94 of 136 waves) (p<0.05). The rate of abnormal SSR according to OH was not significantly different (with OH 75.0%, without OH 75.6%) (p>0.05). The RRIV of stroke patients with OH (1.09±0.06) was significantly lower than in control (1.14±0.05) during rest (p<0.01), and in stroke patients without OH, the RRIV (1.13±0.06) was also significantly lower than in control (1.27±0.22) during Valsalva maneuver (p<0.01). Conclusion: Evaluation of SSR and RRIV could be helpful in detecting dysfunction of autonomic nervous system in post-stroke patients.

      • KCI등재

        RSSI 방식을 이용한 RFID 기반 환자 위치 모니터링 시스템 설계에 관한 연구

        김도성,정채,승호,유선국 대한의료정보학회 2009 Healthcare Informatics Research Vol.15 No.1

        Objective : The location services has been an important research area in the U-Healthcare. The location services in medical environment can be implemented by Radio Frequency Identification (RFID), and Received Signal Strength Indication (RSSI) which is the location tracking method by RFID. In this study, we was designed the Patient Location Monitoring System based on RFID using RSSI method. Methods : The RSSI method is a distance measurement method from reference points to object using the Friis's Principle and the Triangulation. The Patient Location Monitoring System was implemented by XML Data transmitted from the Positioning Server to the application. The Patient Location Monitoring System was designed by C# of Visual Studio 2005 and MS-SQL 2005 Express. Results : The Patient Location Monitoring System had the location-tracking average error of 90.50㎝, the standard-deviation of 13.34㎝ in Open-Space test. And, the designed system had the location-tracking average error of 163.24㎝, the standard-deviation of 16.85㎝ in Closed-Space Test. Also, a patient waiting-list guide performance of the Patient Location Monitoring System had successes of 85~100%. Conclusion : In this study, the Patient Location Monitoring System, combined with both patient location-tracking function and patient waiting-list guide function, was validated by experiments in medical environment and this system can be applicable to patient management and further applications.

      • KCI등재

        The Regulatory Mechanism of 4-Phenylbutyric Acid against ER Stress- Induced Autophagy in Human Gingival Fibroblasts

        김도성,채한정,Bo Li,유기연,Hyo-Won Oh,임현대,Wan Lee,형룡 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.7

        Endoplasmic reticulum (ER) stress is closely connected to autophagy. When cells are exposed to ER stress, cells exhibit enhanced protein degradation and form autophagosomes. In this study, we demonstrate that the chemical chaperone, 4-phenylbutyric acid (4-PBA), regulates ER stressinduced cell death and autophagy in human gingival fibroblasts. We found that 4-PBA protected cells against thapsigargin-induced apoptotic cell death but did not affect the reduced cell proliferation. ER stress induced by thapsigargin was alleviated by 4-PBA through the regulation of several ER stress-inducible, unfolded protein response related proteins including GRP78, GRP94, C/EBP homologous protein, phospho-eIF-2α, eIF-2α, phospho-JNK1 (p46) and phospho-JNK2/3 (p54), JNK1, IRE-1α, PERK, and sXBP-1. Compared with cells treated with thapsigargin alone, cells treated with both 4-PBA and thapsigargin showed lower levels of Beclin-1, LC-3II and autophagic vacuoles, indicating that 4-PBA also inhibited autophagy induced by ER stress. This study suggests that 4-PBA may be a potential therapeutic agent against ER stress-associated pathologic situations.

      • KCI등재

        $Mg_2SiO_4$:Tb(MSO-S) TLD의 광감수성과 방향의존성

        김도성,박명환,Kim, Do-Sung,Park, Myeong-Hwan 대한방사선방어학회 1998 방사선방어학회지 Vol.23 No.1

        $Mg_2SiO_4$:Tb(MSO-S) TLD의 사용에서 부정확한 선량평가의 원인이 될 수 있는 광감수성과 방향 의존성을 조사하였다. 200 lux의 형광등과 백열등 하에서 8시간씩 노출한 경우 각각 약 11 mR과 3 mR의 조사선량에 해당하는 광감수성이 나타났다 그리고 수직입사($0^{\circ}$)에 대한 ${\pm}80^{\circ}$ 의 각도로 입사하는 경우의 열형광강도 비가 MSO-S는 약 0.8, badge형의 MSO-L은 약 0.15로서 방향의존성이 비교적 크게 나타났다. The light sensitivity and angular dependence of the $Mg_2SiO_4$:Tb(MSO-5) TLD which affect the accuracy of the radiation dose measurement are investigated. Light-induced thermoluminescence of MSO-S TLD under the 200 lux fluorescent and the incandescent lamp for 8 hours are corresponding to 11 and 3 mR exposure, respectively. TL intensity ratio of the incident angle of ${\pm}80^{\circ}$ to normal incidence for MSO-S and badge type MSO-L are about 0.8 and 0.15, respectively.

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