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김종민,Kim, Jong-Min 대한용접접합학회 2007 대한용접·접합학회지 Vol.25 No.2
도전성 접착제는 많은 잠재적인 우수한 특성으로 응용범위가 점차로 확대되어 가고 그 시장 규모가 증가하는 추세에 있다. 본 논문에서는 전자패키징에서 널리 사용되어 오던 기존의 솔더를 대체하는 재료로서 도전성 접착제의 기술 동향에 대해 살펴보았다. 최근, 기존의 ECAs의 도전메커니즘(도전입자의 기계적/물리적 접촉)에 기인한 문제점을 극복하기 위한 나노입자를 사용한 여러형태의 ECAs와 접속 기술들이 활발히 개발 되고 있다. 앞서 언급한 바와 같이, ECAs가 가지는 낮은 전기도도와 불안정한 전기적 특성을 향상시키기 위한 개선하기 위한 도전입자 및 폴리머 주재의 성능향상을 위한 연구가 활발히 진행되고 있지만 이러한 문제점을 극복할 새로운 재료의 개발 및 공정에 대한 연구가 필요한 것으로 판단된다. 또한, 최근 급속하게 전개되고 있는 전자 패키징 분야의 경박단소화, 고기능화, 다기능화 추세에 따른 미세피치화, 고전력/고주파 대응, 발열 문제 등의 해결할 수 있는 새로운 재료 및 공정에 대한 연구 개발은 가속화 될 것으로 보인다.
Pulmonary vein aneurysm in a New Zealand White rabbit: a case report
김종민,우창곡,김사훈,정의숙,김길수,강병철 한국실험동물학회 2022 Laboratory Animal Research Vol.38 No.1
Background: Pulmonary venous aneurysm (PVA) is a rare condition characterized by aneurysmal dilatation of the pulmonary vein in humans. The diagnosis is incidental usually as there are no clinical symptoms. This case report describes a histological diagnosis of PVA in a New Zealand White rabbit. Case presentation: A 1.5-kg male New Zealand White rabbit was acclimatized in an animal room for 5 weeks until the experiment began. However, the rabbit was found dead, with signs of nasal hemorrhage. Necropsy revealed tracheal and pulmonary hemorrhage, and the epistaxis had a pulmonary origin. PCR and ELISA to detect antigens and antibodies pertaining to the rabbit hemorrhagic disease virus showed negative results. Multiple ballooning lesions (50–200 μm size) in the pulmonary veins were observed on histological examination, and PVA was diagnosed. Death was attributed to a spontaneous rupture of the PVA and massive hemorrhage into the lung parenchyma that extended into the trachea and nasal passages. Conclusions: To the author’s best knowledge, this is the first report of a PVA in a rabbit.
김종민,박정규 한국실험동물학회 2021 Laboratory Animal Research Vol.37 No.2
Background The objective of this study was to investigate whether the use of live attenuated varicella zoster virus (VZV) MAV vaccination can efficiently induce VZV antibody production in naive rhesus monkeys as an approach to prevent simian varicella virus (SVV) reactivation in animals immunosuppressed for transplantation studies. Results Clinically available human VZV vaccine was used to induce the production of anti-VZV antibodies in rhesus monkeys. A vial of the vaccine was subcutaneously injected at 0 week, and the second and third vaccination was performed at 5 and 6 weeks by intratracheal inoculation. The titer of anti-VZV IgG was assessed at 0, 2, 4, 6, and 7 weeks. At 2 weeks, 3/16 were seropositive for VZV IgG. At 6 weeks, 9/16 were shown to be seropositive. At 7 weeks, 16/16 were found to be seropositive. Conclusions The VZV vaccine via intratrachael inoculation was shown to induce VZV IgG humoral immunity in rhesus monkeys and may be important immunosuppressed macaques for transplantation studies. Although the humoral immunity produced is an important finding, further studies will be necessary to confirm possible protection and it could protect probably against SVV infection in rhesus monkey.
김종민,서상우,신동희,이하승,김주환,장찬욱,김성,최석호 한국물리학회 2017 Current Applied Physics Vol.17 No.8
Graphene/silver nanowires (Ag NWs)-doped graphene stacks are employed for Si Schottky-junction solar cells as transparent conductive electrodes (TCEs). The doping of graphene by Ag NWs decreases the series resistance of the solar cells and enhances the electrical conductivity of the graphene TCEs, resulting in remarkable improvements of the diode properties of the solar cells. In addition, the Ag NWs on the graphene reduces the reflectance of the solar cells as well as the transmittance of the graphene TCEs. This trade-off correlation makes the power-conversion efficiency maximized to 3.51% at concentration of Ag NWs (nA) ¼ 0.1 wt%. The long-term stabilities of the photovoltaic properties are greatly improved by the encapsulation of the Ag NWs/graphene TCEs with another graphene because of the excellence of graphene as a gas-barrier. These and other nA-dependent behaviors of Raman spectra, work function, sheet resistance, external quantum efficiency, and DC conductivity/optical conductivity ratio are discussed to explain the photovoltaic properties of the solar cells.
Diagnosis and treatment of macrocytic anemia in a perinatal common marmoset: a case report
김종민,곽진아,임현진,김주일,강병철 한국실험동물학회 2022 Laboratory Animal Research Vol.38 No.1
Background: The common marmoset is widely used in current biomedical research for various research fields. We observed macrocytic anemia in a perinatal common marmoset with gradual weight loss and diarrhea. The objective of this case report is to describe the diagnosis and treatment of macrocytic anemia in a perinatal common marmoset. Case presentation: A 7-year-old female common marmoset showed clinical signs of gradual weight loss and intermittent diarrhea beginning 3 months after giving birth. Macrocytic anemia was diagnosed due to a decreased red blood cell (RBC) count, low hemoglobin level, and increased mean corpuscular volume (MCV). Multivitamins containing cobalamin and folate were administered for 7 days, and the patient’s RBC count recovered to near the normal range with this treatment. Conclusions: Macrocytic anemia can be diagnosed by evaluating the MCV on a complete blood count (CBC) and cobalamin or folate levels and be treated by supplementation with cobalamin and folate. Such supplements may be needed during pregnancy and lactation in female common marmosets and/or in animals with chronic diarrhea.