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      • SCOPUSKCI등재

        토끼에서 EPO(Erythropoietin)의 안점막자극성 및 피부자극성시험

        강병철,남정석,제정환,이석만,양재만,이학모,박재학,송동호,유선희 한국독성학회 1997 Toxicological Research Vol.13 No.1

        This test was performed to evaluate the ocular and skin irritation of EPO (Erythropoietin). The results as follows: 1. Ocular irritation test There were no observed clinical signs, body weght changes by EPO during experimental period. The acute ocular irritation index(A.O.I.), mean ocular irritation index(M.O.I.) and Day-7 individual ocular irritation index(I.O.I.) of EPO at dose of 1000U and 10, 000U were 0, respectively. Therefore we evaluated that EPO was non-toxic to eyes. 2. Skin irritation test There were no observed clinical signs, body weght changes and gross pathologic findings by EPO during experimental period. There were no observed erythema, eschar formation and edema formation on intact and abraded skin treated by EPO. The primary irritation index(P.I.I.) of EPO at dose of 1000U and 10, 000U were 0, respectively and were evaluated none irritating product about skin irritation.

      • KCI등재

        청소년 성소수자의 긍정적 성정체성 형성과정에 관한 질적연구

        강병철,하경희 한국청소년학회 2012 청소년학연구 Vol.19 No.2

        The purpose of this qualitative study is to understand how sexual identity is positively developed in sexual minority youth. To achieve this, in-depth interviews were conducted with seven sexual minority youths and the findings were analyzed. The results show that the sexual identity processes fall into three categories: 1) I'm different from others, 2) I'm looking at myself through society, and 3) I, as a sexual minority. Multiple factors cause sexual minority youth to understand that they are different from others. As they see the attitudes of the straight majority toward LGBTQ (Lesbian, Gay, Bisexual, Transgendered, Questioning)s at home and school, they begin forming seriously thought about their identity as a sexual minority. In addition, in their interaction with the LGBTQ community, they experience various relationships and begin to actively hew out a life for themselves. These results show the spread of LGBTQ culture in our society and the change of younger generation. Based on the results some advice is suggested for policy and practice. 본 연구는 청소년 성소수자들 중 긍정적으로 성정체성을 형성해 나가는 청소년들을 대상으로 질적연구를 통해 그 과정과 경험을 이해하고자 하였다. 눈덩이 표집을 통해 모집한 7명의 청소년 성소수자를 대상으로 심층면접을 실시하였다. 분석결과 ‘남과는 다른 나’, ‘사회라는 거울을 통해 바라본 나’, ‘성소수자로서의 나’라는 3개의 범주와 9가지 주제가 도출되었다. 우리 사회에서도 성소수자들의 활동과 문화가 확대되어 다양한 정보와 커뮤니티가 활성화된 가운데, 청소년 성소수자들은 다양한 통로를 통해 자신의 성정체성을 적극적으로 탐색해 나갔다. 학교와 가정 등 사회에서 성소수자를 바라보는 시선과 태도가 여전히 부정적이고 때로는 위협적인 현실에 부딪히면서 현실적인 고민들을 해나가게 되었다. 하지만 성소수자 커뮤니티와의 교류 속에서 자신의 성정체성에 대해 어느 정도 개방적이고 유연한 태도를 가지고 성소수자로서의 삶을 적극적으로 모색해 나가고자 하였다. 이를 통해 우리 사회에서 성소수자 문화의 확대와 이전 세대와는 다른 청소년 세대의 변화를 확인할 수 있었다. 연구결과를 바탕으로 청소년 성소수자에 대한 논의와 제언을 제시하였다.

      • KCI등재

        Vancomycin에 대한 약물사용검토

        강병철,이은숙,박경호,신완균,조남춘 한국병원약사회 1998 병원약사회지 Vol.15 No.3

        By criteria of American Society of Hospital Pharmacists (ASHP) and criteria revised informally, drug use evaluation (DUE) on vancomycin, Ⅳ to treat adult inpatients of Seoul National University of Hospital with was reviewed retrospectively. Total 81 charts of adult inpatients who were ordered vancomycin between June and July 1998 were reviewed but 15 cases were excluded for poor data, so the data of 66 patients were collected. Fifty nine percentage were met with criteria for the justification of use, the rest 41% were deviated from the criteria. In analyzing process indicators, appropriate initial dosage, the elements of measuring serum vancomycin level, and duration of therapy were unacceptable above 50%, especially. In the elements of complication were met with the criteria well, but this result was derived from the defect of the retrospective study. In outcome measures, negative cultures within 24 hours after discontinuation were infrequently performed among 3 elements. In revised criteria informally, percentage of the elements met criteria was increased slightly. As a result, the difference of data between 1991 and 1998 was not significant. For strict usage, formal usage guidelines for antibiotics at Seoul National University Hospital like criteria of ASHP, pharmacists joining with infection team, and ward-resident pharmacists monitoring adverse drug reactions prospectively, are needed.

      • KCI등재
      • KCI등재

        A Newly Designed Y-shaped Covered Stent in the Palliative Treatment of Hepatic Hilar Malignant Obstruction: Case Report

        강병철,이소원,정환훈 대한영상의학회 2013 Korean Journal of Radiology Vol.14 No.1

        We report a case in an inoperable patient with the hilar malignant biliary obstruction treated palliatively by the use of a newly designed Y-shaped covered stent without interfering contra-lateral bile duct. We percutaneously inserted a newly designed Y-shaped covered stent into a biliary tree in an inoperable patient with Bismuth Type II cholangiocarcinoma. We checked tubograms, enhanced CT studies, and blood bilirubin levels before, one week after, and at every three month after the stenting, by observing closely the signs of clinical infection as well. The follow-up period was about 12 months. The placement of the Y-shaped covered stent was successful and resulted in adequate biliary drainage in the immediate post-procedural tubogram and in the follow-up abdominal CT. The serum bilirubin levels did not show elevation after the insertion of the Y-shaped covered stent.

      • KCI등재후보

        스트레스에의한 여성 울증(鬱證) 환자의 가미소요산(加味逍遙散) 치험 3례

        강병철,성경화,송일헌,김의철,권도익,박경훈,정성민,박준하,고은상,Kang, Byung-Chul,Sung, Kyoung-Hwa,Song, Il-Hun,Kim, Ui-Chul,Kwon, Do-Ik,Park, Kyung-Hoon,Jung, Sung-Min,Park, Jun-Ha,Ko, Eun-Sang 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.3

        UL-syndrome(鬱證) is a syndrome of emotional depression and various physical symptoms generally due to chronic psychological stress, without constitutional abnormality. These are cases of female patients suffering from headache, chest discomfort, heart burning, insomnia, dyspepsia, anorexia, fatigue and some other minor symptoms due to chronic stress. We diagnosed these cases as UL-syndrome and treated them with oriental medicine, specifically Gamisoyosan(加味逍遙散). This paper describes the symptoms that the patients suffered, the treatment used, and identifies stages in the development of UL-syndrome, and suggests a stage in which Gamisoyosan is efficacious.

      • Kluyveromyces frgilis 유래 고정화 β-galactosidase의 유당 분해에 대한 속도 상수 결정

        강병철 東義大學校産業技術開發硏究所 2011 産業技術硏究誌 Vol.25 No.-

        β-Galactosidase is widely used for the hydrolysis of lactose in milk. The kinetic parameters of this enzyme for free and immobilized case were determined using integrated reaction rate equations. The main variables for the determination of kinetic parameters were the concentration of enzyme, the concentration of substrates, and temperature. Two kinetic models investigated in this study were Michaelis-Menten and Michaelis-Menten with competitive product inhibition. These models were compared with experimental results by means of nonlinear regression analysis using the minimization of a residual sum of square. Applying statistical and physical criteria, a Michaelis-Menten with a competitive inhibition by galactose predicted the best results, yielding a good fitting of the experimental data.

      • SCOPUSKCI등재

        상악동후벽에 발생한 낭형 복합치아종

        강병철,Kang Byung-Cheol 대한영상치의학회 1998 Imaging Science in Dentistry Vol.28 No.2

        A cystic compound odontoma in the maxillary sinus occurred in a 13-year-old boy. who had missing right upper third molar without having the history of extraction of the wisdom tooth. He complained nasal stuffiness. headache. and pain on the affected face. resembling any sign and symptoms of the maxillary sinus problems. The cystic compound. sized 2 x 1.5 cm in diameter was pedunculated and attached on the posterior wall of the right maxillary sinus and above the antral floor. The location of the compound odontoma in the maxillary sinus was confirmed after panoramic. waters. spiral tomographic. CT examinations and surgical exploration. Its location was on the medial. posterior. superior to the normal position of the maxillary third molar or the maxillary dental arch. The cystic odontoma in the maxillary sinus made the patient have the signs and symptoms of maxillary sinusitis. The cystic compound odontoma might be originated from the dental lamina of the missing upper right third molar. The 'V principle' of the upper jaw growth and the pneumatization process of the maxillary sinus could explain why the compound odontoma had peduncular shape and the location of odontoma was on the medial. superior to the normal position of the maxillary dental arch.

      • SCOPUSKCI등재

        졸-겔법으로 제조된 SiO<sub>2</sub>막의 적외선 복사특성에 관한 연구

        강병철,김영근,김기호,Kang, Byung-chul,Kim, Young-geun,Kim, Ki-ho 한국재료학회 2003 한국재료학회지 Vol.13 No.10

        FT-IR and thermograph were used to investigate the infrared radiation characteristics of $SiO_2$film made by the sol-gel method. FT-IR spectrum of the $SiO_2$film showed high infrared absorption by Si-O-Si vibration at 1220, 1080, 800 and cm$460^{-1}$ The infrared absorption and radiation wavelength ranges of the $SiO_2$film measured by the integration method coincided with the reflection method, and the infrared emissivity was 0.65, equally. Depending on the bonding of elements, the infrared emissivity was high in the wavelength range where the infrared absorption rate was high, that follows the Kirchhoff's law. The emissivity showed the highest value in the wavelength range between $8∼10\mu\textrm{m}$. $SiO_2$film was considered as an efficient materials for infrared radiator at temperature below 10$0^{\circ}C$. The heat radiation temperature was $117^{\circ}C$ for the aluminum plate, but $146^{\circ}C$ for the $SiO_2$film after 7 minutes heat absorption, consiquently, $29^{\circ}C$ higher than the former.

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