다제내성 조절제의 탐색

김세은,이정준 한국산업미생물학회 1996 생물산업 Vol.9 No.2

Estradiol valerate에 의해 유발되는 다낭성난소증후군의 Nerve Growth Factor 변화

김세은,임성철,정문진,최백동,김승현,고아라,서승용,강성수,문창종,김종춘,김성호,배춘식 한국임상수의학회 2011 한국임상수의학회지 Vol.28 No.4

A form of polycystic ovary (PCO) resembling some aspects of the human PCO syndrome (PCOS) can be induced in rats by a single injection of estradiol valerate (EV). An increase in sympathetic outflow to the ovary precedes, by several weeks, the appearance of cysts, suggesting the involvement of a neurogenic component in the pathology of this ovarian dysfunction. To test the hypotheses that the change in sympathetic tone is related to an augmented production of hippocampal and/or ovarian nerve growth factor (NGF), and that this abnormally elevated production of NGF contributes to the induction of PCOS induced by EV. The animals were sacrificed after PCOS induction and the ovaries and hippocampus were sectioned and compared to the normal control. The expression of NGF was measured by immunohistochemical staining and Western blot analysis in the ovaries and hippocampus. EVinduced PCOS showed significant increase of ovarian NGF expression. Immunohistochemical expression of NGF was confined to the follicular cells and interstitial cells. Hippocampal NGF expression was not significantly changed. In conclusion EV-induced PCOS was related to the ovarian sympathetic activation which was mediated by NGF.

건강한 미니돼지에서 간담도 기능의 핵의학적 평가

김세은,심경미,유경훈,이원국,최석화,박수현,한호재,강성수 한국임상수의학회 2007 한국임상수의학회지 Vol.24 No.4

The purpose of this study is to investigate normal hepatobiliary functions in healthy miniature pigs. 99mTcDISIDA hepatobiliary scintigraphy (HBS) was used for it. Five mCi dose of 99mTc-DISIDA was injected intravenously into 3 healthy adult miniature pigs, and dynamic images were obtained during 1 hour. 99mTc-DISIDA HBS in a miniature pig was evaluated for 6 variables. A cardiac washout occurred within 1 min in all miniature pigs, and radioactivities in the gallbladder were not detected in two miniature pigs. Thus, the initial radioactivity and Tmax of the gallbladder were non-available to identify. Mean Tmax of liver was 8.67 ± 2.08 min and initial small intestinal radioactivity was seen at 9.67 ± 2.52 min after 99mTc-DISIDA injection. Mean hepatic washout time was not detected in 60 min dynamic images. Therefore, 99mTc-DISIDA HBS is the effective diagnostic method to evaluate the function of hepatocyte and bile flow rate. However, it was not a proper method to evaluate the function of gallbladder, which indicates that an additional study is needed to further specify the reasons for the absence of radioactivities in gallbladder of two miniature pigs

기자상을 바라보는 기자들의 인식

김세은 관훈클럽 2013 관훈저널 Vol.- No.129

Clinical Effect of Guide Bone Regeneration of Mandibular Nonunion in a Geriatric Dog

김세은,심경미,배춘식,최석화,정순정,강성수 한국임상수의학회 2013 한국임상수의학회지 Vol.30 No.2

A 13-year-old, 4.2 kg female poodle was referred for failure of first bilateral mandibular surgery at a local animal hospital after pathologic fracture. Surgery was performed with 2.0-mm miniplates/screws and porcine cancellous bone grafts. In addition, because of the large size of the right segmental defect, a barrier absorbable membrane was employed for guide bone regeneration on right mandible. After surgery, follow-ups performed at 1 day, 1, 4, 8, and 12 weeks; there were no signs of dental malocclusion, nonunion or soft tissue infection. However, a 1-year longterm follow-up showed nonunion in the left mandibular fracture site for which a collagen membrane had not been used. It is considered that use of porcine bone graft with barrier absorbable membrane may be effective for the repair of mandibular nonunion in a geriatric dog.

앙트러프러너십에 따른 뷰티행동 및 관리적·기술적 역량 연구 -미용서비스 종사자를 대상으로-

김세은,오수연,박철우 한국미용학회 2019 한국미용학회지 Vol.25 No.5

The characteristics of the beauty service industry are the labor - intensive industry type in which human resources are highly dependent on the human aesthetic desires of technology and services, which are not handled by physical systems. Such human dependence is high and it is perceived as an important factor through the personal, organizational and innovative activities with entrepreneurship for the continuous growth and development of the cosmetic service industry, where small-scale capital enterprises are scattered. The venture runner for enhancing the competitiveness of the cosmetics service industry will act as a high value-added driving force, so that it can be expected to have an effect on managerial and technical competence. First, the venture runners of the beauty service industry showed a significant influence on beauty behavior. Behavioral behaviors were most perceived in beauty behavior, but innovation and risk sensitivity did not affect beauty behavior. Second, as a result of the influence on the venture runner management capacity and technological capacity, the higher the risk sensitivity, initiative, and innovation, the higher the managerial capacity of the beauty worker. However, if technological competence is advanced and innovation is high, technical competency is increased, but risk sensitivity is not technically competent. Third, the higher the perceived beauty behaviors, the more the managerial and technological competence affected the beauty behavior. Fourth, in the relationship between entrepreneurship and managerial and technical competence, mediating effects of beauty behavior on the relationship between innovativeness, initiative, risk sensitivity and managerial competence and technical competence.

복시를 주소로 내원한 에드하임-체스터병 1예

김세은,김숙영,김근해,Se Eun Kim,Sook Young Kim,Keun Hae Kim 대한안과학회 2014 대한안과학회지 Vol.55 No.2

Purpose: We present a case of Erdheim-Chester disease (ECD) with diplopia. Case summary: A 56-year-old woman came to the hospital with a 6-week history of diplopia on left lateral gaze. The right eye showed mildly limited adduction. Humphrey automated perimetry demonstrated inferior bitemporal quadrantanopia. Orbital and brain magnetic resonance imaging revealed well-defined orbital masses in both intraconal orbits with homogenous enhancement, as well as multiple masses of homogenous signal intensity in the brain. Systemic evaluation showed involvement of the long bones, and retroperitoneum, but no involvement of the heart, or lungs. Incisional biopsy of the right orbital mass was performed. Histopathological examination showed numerous lipid-laden histiocytes and few multinucleated Touton giant cells. Immunohistochemical staining showed positivity for CD68, but negativity for CD1a, and ECD was therefore diagnosed. The patient received treatment with radiation therapy and interferon-α, but died due to sepsis secondary to urinary tract infection after 2 months. Conclusions: Except exophthalmos, diplopia may be the only initial symptom of an orbital mass. Although rare, the possibility of ECD should be considered in the differential diagnosis of both retrobulbar and orbital masses with diplopia. J Korean Ophthalmol Soc 2014;55(2):283-288

고종초기(1864년~1873년)의 經筵

金世恩 진단학회 2000 진단학보 Vol.- No.89

여중생들의 화장에 대한 인식과 사용실태에 관한 연구

김세은,김주덕 한국화장품미용학회 2019 한국화장품미용학회지 Vol.9 No.2

There is a tendency that modern society is under the huge influence of the Internet owing to one-person media environments. Specifically, girl students, who are in adolescence where there are mounting concerns for appearance and makeup, often rely on and accept massmedia like beauty blogs as a means of information gathering. Consequently, they are likely to obtain makeup information easily and to get into trouble such as the side effects of cosmetics and impulse buying relying on knowledge by acquiring knowledge that is incorrect or unfit for them. The purpose of this study was to examine the necessity of cosmetology education, makeup awareness and the state of cosmetics usage in an effort to create the right makeup culture among middle school girls. Data were collected by conducting a survey on the girl students who were in their first, second and third grades in middle school in North Jeolla Province. 590 questionnaires were analyzed by SPSS statistical package for the social science 25.0 version for Windows. The major findings of the study were as follows. Who considered skincare and makeup education to be necessary at school accounted for 72.4 percent. 73.4 percent used makeup cosmetics, and the largest group that accounted for 57.7 percent put on makeup on their whole faces (skin+lips+eyes). As makeup is already in full swing with teenagers and more types of makeup cosmetics are being used, we should set up a beauty course beauty in school education programs so that they can be used properly by providing and educating cosmetic-related information. 현대사회는 1인 미디어의 환경을 기반으로 인터넷의 영향을 많이 받고 있는 추세이다. 특히 외모에 대한 관심과 화장에 대한 관심이 높아지는 청소년시기의 여학생들은 뷰티 블로그와 같은 매스미디어를 정보수단의 매체로 의존하고 받아들이는 경우가 많다. 그에 따라 쉽게 화장에 관한 정보를 얻고 자신에게 맞지 않는 잘못된 지식의 습득으로 화장품에 대한 부작용과 제품의 충동구매와 같은 문제를 일으킬 수 있다. 이에 본 연구는 여중생들의 올바른 화장 문화를 만들어 가는 것에 목적을 두고 미용교육 필요성과 화장인식 및 화장품 사용실태를 연구하고 분석하였다. 본 연구의 자료 수집은 설문조사를 통해 실시되었으며 전라북도 지역의 중학교 1, 2, 3학년 여학생을 대상으로 총 590부를 SPSS(Statistical Package for the Social Science) WIN 25.0 프로그램을 이용하여 분석하였다.이로써 얻어진 주요 결과는 다음과 같다. 학교에서 피부관리 및 화장에 관한 교육이 필요하다고 인식하는 학생은 72.4%로 나타났다. 73.4%의 여중생이 메이크업 화장품을 사용하였고, 얼굴 전체화장(피부+입술+눈)을 하는 학생이 57.7%로 가장 높게 나타났다.이미 메이크업이 청소년들에게 본격화 되어 있고 사용하는 메이크업 화장품의 종류도 더욱 많아지고 있는 추세인만큼, 학교 교육 프로그램에 미용을 편성하여 화장품 관련 정보를 제공하고 교육시킴으로써 올바르게 활용할 수 있도록 해야 할 것이다.

The Effect of Cetylpyridinium Chloride on Halitosis and Periodontal Disease-related Parameters in Dogs

김세은,김종춘,김성호,박돈희,김도만,심경미,Kyeong Hoon Yoo,배춘식,Ji-Won Ryu,강성수 한국생물공학회 2008 Biotechnology and Bioprocess Engineering Vol.13 No.2

Periodontal disease is an oral disease common in middle-aged dogs and cats, with halitosis being the most common sign. There are many commercial products containing chlorhexidine, cetylpyridinium chloride (CPC), zinc salts and essential oils for controlling halitosis and periodontal disease. CPC is a quaternary ammonium compound and has a broad spectrum antimicrobial activity. In this study, oral spray (OS) and gel (OG) containing CPC was applied to the dogs’ teeth twice daily for 3 weeks, and their effect in controlling periodontal disease and halitosis was examined. In the 3-week study, OS and OG were significantly effective in controlling plaque, calculus, and halitosis. Therefore, the OS and OG containing CPC were effective in controlling periodontal disease and halitosis in dogs.