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Hwang, Hye Jeon,Kim, Kyoung Won,Jeong, Woo Kyoung,Song, Gi-Won,Ko, Gi-Young,Sung, Kyu Bo,Shin, Yong Moon,Kim, Pyo Nyun,Ha, Tae-Yong,Moon, Deok-Bog,Kim, Ki-Hun,Ahn, Chul-Soo,Hwang, Shin,Lee, Sung-Gyu Radiological Society of North America 2009 Radiology Vol.253 No.2
<P>PURPOSE: To establish optimal Doppler ultrasonographic (US) venous pulsatility index and computed tomographic (CT) criteria for right hepatic vein (RHV) stenosis after living donor liver transplantation (LDLT) and to compare accuracies of these methods by using receiver operating characteristic (ROC) analysis. MATERIALS AND METHODS: This retrospective study was approved by an institutional review board; informed consent was waived. Eighty patients (48 men, 32 women; mean age, 51.5 years +/- 9.2 [standard deviation]) underwent Doppler US and CT within 8 days of hepatic venography following right lobe LDLT between October 2006 and September 2008. At venography, RHVs were classified into a stenosis or nonstenosis group. At Doppler US, venous pulsatility index was defined as the difference between maximum and minimum frequency shifts divided by maximum frequency shift. At CT, diameters of anastomosis and RHV were measured; percentage of stenosis was calculated. Mean Doppler US and CT parameters in the two groups were compared; ROC analysis was performed. RESULTS: There were 30 stenotic and 50 nonstenotic RHVs. Mean venous pulsatility index and mean anastomosis diameter were significantly lower and mean percentage of stenosis was significantly higher in the stenosis than the nonstenosis group (P < .001 each). Optimal cutoffs for venous pulsatility index, anastomosis diameter, and percentage of stenosis were 0.16, 3.7 mm, and 47%, respectively. Sensitivity and specificity were 86.7% and 68.0% for venous pulsatility index, 96.7% and 88.0% for anastomosis diameter, and 96.7% and 86.0% for percentage of stenosis, respectively. At ROC analysis, anastomosis diameter (P = .002) and percentage of stenosis (P = .003) were significantly more accurate than venous pulsatility index. CONCLUSION: CT is more accurate than Doppler US for RHV stenosis after LDLT, with venous pulsatility index as the sole sonographic criterion. Patients suspected of having RHV stenosis at Doppler US may benefit from CT to reduce unnecessary venography.</P>
Hwang, Kyoung-Sub,Lee, Jin-Ju,Jeon, Young-Chan,Shin, Sang-Hun,Song, Jae-Min,Lee, So-Hyoun,Huh, Jung-Bo Korean Academy of Dental Science 2017 Journal of korean dental science Vol.10 No.1
In case of loss of many teeth due to dental caries or periodontal disease, improvement of masticatory function and aesthetics can be obtained through implant treatment. However, if the patient does not have a normal intercondylar relationship, it is difficult to achieve an ideal occlusal relationship with only prosthetic treatment. In particular, oral reconstruction with orthodontic treatment or orthognathic surgery is necessary for patients with mandibular prognathism. However, if the posterior occlusion collapses due to severe caries or periodontal disease, orthognathic surgery may be difficult. The occlusal vertical stop is very important for the stability of the mandibular position during occlusal reconstruction through orthognathic surgery. The patient in this case had posterior occlusion collapsed due to the caries of a large number of posterior teeth, and showed mandibular prognathism and long face. We planned a full arch restoration with orthognathic surgery and extracted the hopeless teeth. To secure the vertical stop required for orthognathic surgery, the implant was placed before surgery. After the orthognathic surgery and the final prosthesis application, the results were satisfactory for the improvement of the aesthetics and the restoration of the masticatory function.
( Bo Hye Kim ),( Hee Kyung Kim ),( Hye Jeong Cho ),( So Dam Hong ),( Jae Kyoung Shin ),( Hee Jin Hong ),( Sae Ahm Kim ),( Hak Su Kim ),( Suk Pyo Shin ),( Ha Na Park ),( Seong Gyu Hwang ),( Kyu Sung Ri 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Pyogenic liver abscess is the most common type of visceral abscess with a mortality rate of 10% to 25%. The mortality of liver abscess markedly decreased due to the improvement of diagnostic methods, antibiotics and other treatment modalities. We describe the clinical feature, changing trends of etiology and poor prognostic factors of pyogenic liver abscess during the recent 2 decades. Methods: We retrospectively reviewed the medical records of patients with pyogenic liver abscess who were treated in CHA Bundang Medical Center between 1996 and 2014. The period was divided into period 1 (1996-2004) and period 2 (2005-2014). We compare these two groups in age, etiology, etc. Results: 148 patients were indentifi ed. 60 patients were included period 1 and 86 patients were included period 2. There were no signifi cant interval changes in symptom, sign, number and size of abscess and laboratory fi nding between the two periods. The average age increased in period 2 (aged 62. 7) relative to period 1 (aged 57. 2) (P=0. 001). Klebsiella pneumoniae was the most common pathogen both two periods. The most common infection route was biliary tract (45. 5%) in period 1 and cyptogenic cause (53. 8%) in period 2 (P=0. 042). Interestingly, the percentage of hepatobiliary malignacy in etiology increased from 4. 5% in Period 1 to 10. 2% in period 2. (P= 0. 03) Liver abscess originated from hepatobiliary problem showed a higher recurrent rate (P=0. 018). Conclusions:The average age of patients with pyogenic liver abscess has increased substantially and the predominant pathogen originates from the biliary tract because biliary procedures has increased. Hepatobiliary malignancy is the major risk factor and poor prognostic factor for pyogenic liver abscess. Therefore early diagnosis and close observation is important for patients with biliary problem or hepatobiliary malignancy.
Sex Ratio Determination by Quantitative Real Time PCR using Amelogenin Gene in Porcine Sperm
Hwang, You-Jin,Bae, Mun-Sook,Yang, Jae-Hun,Kim, Bo-Kyoung,Kim, Sang-Ok,Lee, Eun-Soo,Choi, Sun-Gyu,Kwon, Ye-Ri,Seo, Min-Hae,Park, Choon-Keun 韓國受精卵移植學會 2009 한국동물생명공학회지 Vol.24 No.3
Sex-sorting of sperm is an assisted reproductive technology (ART) used by the livestock industry for the mass production of animals of a desired sex. The standard method for sorting sperm is the detection of DNA content differences between X and Y chromosome-bearing sperm by flow cytometry. However, this method has variable efficiency and therefore requires verification by a second method. We have developed a sex determination method based on quantitative real-time polymerase chain reaction (qPCR) of the porcine amelogenin (AMEL) gene. The AMEL gene is present on both the X and the Y chromosome, but the length and sequence of its noncoding regions differ between the X and Y chromosomes. By measuring the threshold cycle (Ct) of qPCR, we were able to calculate the relative frequency of X chromosome. Two sets of AMEL primers were used in these studies. One set (AME) targeted AMEL gene sequences present in both X and Y chromosome, but produced PCR products of different lengths for each chromosome. The other set (AXR) bound to AMEL gene sequences present on the X chromosome but absent esholthe Y-chromosome. Relative product levels were calculated by normalizing the AXR fluorescence to the AME fluorescence. The AMEL method accurately predicted the sex ratios of boar sperm, demonstrating that it has potential value as a sex determination method.
Bo Kyoung Choi,Soo Hyun Yang,Kang Hum Suh,Jin Ah Hwang,Moon Hyung Lee,Won keun Si,Ji Ho Kim 전남대학교 의과학연구소 2011 전남의대학술지 Vol.47 No.3
Portal vein thrombosis (PVT) is a rare form of venous thrombosis that affects the hepatic portal vein flow, which can lead to portal hypertension. Treatment of PVT includes anticoagulants,thrombolysis, insertion of shunts, bypass surgery, and liver transplantation. Single anticoagulation therapy is not regarded as a curative treatment but can be associated with a reduction in new thrombotic episodes. We experienced a case of acute total occlusion of PVT provoked by protein C and S deficiency syndrome. PVT was completely recanalized with oral anticoagulant therapy following low molecular weight heparin therapy.
청소년기 여자에서 고칼슘 섭취가 아연과 구리 평형에 미치는 영향
최보영(Bo-Young Choi),남혜경(Hye-Kyoung Nam),황용주(Young-Joo Hwang),김선희(Sun-Hee Kim) 한국식품영양과학회 2001 한국식품영양과학회지 Vol.30 No.5
건강한 16세 여고생 8명에게 한국인 권장량 수준인 800 mg의 칼슘을 함유한 정상칼슘식사를 1주간 섭취시키고, 그 다음 주에 1200 mg Ca을 함유한 고칼슘식사를 제공하였다. 이 때 정상칼슘식사에서는 6.57 mg의 아연과 910 μg의 구리를 함유하였으며 고칼슘식사에서는 6.37 mg의 아연과 812 μg의 구리를 평균적으로 함유하였다. 해당 식사를 제공하고 4일째부터 3일간 뇨와 대변을 매일 수집하였으며 음식과 뇨, 변 중 구리와 아연 함량을 정량분석하여 외견적 흡수율 및 체내 보유량을 계산하였다. 구리 및 아연의 평형대사 실험을 한 결과를 요약하면 다음과 같다. 아연의 대사평형을 보면, 고칼슘식사 섭취시의 뇨와 대변 중 아연 배설량은 정상칼슘식사시에 비해 증가하는 경향을 보였다. 그리고 아연의 체내 보유량은 고칼슘식사 섭취시 유의적으로 감소하였다(p<0.05). 구리의 대사평형을 보면, 고칼슘식사 섭취시 대변을 통한 구리 배설량은 19.2 μg으로 정상칼슘식사시의 11.4 μg에 비해 유의적으로 증가하였으며, 따라서 외견적 흡수율은 유의적으로 감소하였다(p<0.05). 소변을 통한 구리의 배설은 거의 나타나지 않았다. 또한 구리의 체내 보유량은 고칼슘식사시에 792 μg으로 정상칼슘식사시의 899 μg에 비해 유의적으로 감소하였다(p<0.05). 이상의 결과를 종합해 볼 때 1200 mg의 칼슘식사를 섭취하면 청소년기 여성에게서 구리와 아연의 외견적 흡수율이 감소하고, 대변을 통한 배설이 증가하며, 체내보유량은 유의적으로 감소하는 등 대사에 영향을 미침을 알 수 있었다. 그러므로 칼슘의 다량 섭취는 미량원소의 대사에 크게 영향을 미칠 수 있으므로 필요한 미량원소의 경우 장에서 흡수시에 무기질간의 경쟁을 고려하여 적절한 양을 섭취하도록 권장량 설정에서 고려해야 할 것이다. Intakes and excretions of zinc and copper were determined for 8 female adolescents (aged 16.4±0.5 y; body mass index 20.4±1.3 kg/㎡; body fat 33.3±2.5%; bone mineral density of lumbar spine in L2-L4; 0.96±0.08 g/㎠) when they consumed diets basal and high in calcium for 6 days each. All subjects consumed a basal Ca diet containing 800 mg, Korean RDA level of the subjects, and a high Ca diet containing 1200 mg, RDA plus 2 SDs of calcium intake. The diets provided 58% of energy intake as carbohydrate, 25% as fat, and 17% as protein. Food, urine and fecal samples were collected during the last 3 days of each feeding period and were assayed. Mean daily intakes on the basal and high calcium diets, respectively, were 6.57 and 6.37 mg for zinc and 910 and 812 μg for copper. Fecal excretion of copper and zinc in relation to intake was significantly greater on the high calcium than on the basal calcium diet. Hence, apparent absorption rate was significantly lowered from 98.7% on the basal calcium diet to 97.9% on the high calcium diet for zinc and from 66.3% to 56.4% for copper, respectively. Urinary loss of copper was not detectable but that of zinc was 0.38 mg on the basal diet and 0.47 mg on the high calcium diet. Copper retention was 899±105 μg/day on the basal calcium diet and 792±20.8 μg/day on the high calcium diet, and zinc retention was 3.95±0.91 mg/day and 3.11±0.89 mg/day. Thus, copper and zinc retention was significantly decreased on the high calcium diet (p<0.05). Summarizing the results, apparent absorption and retention of zinc and copper were significantly decreased by calcium supplementation. Therefore, it is suggested that interactions among minerals should be considered in determining RDA.