실험적 연구에서 생명윤리와 개인정보 보호

김옥주(Kim Ock-Joo) 한국역학회 2007 Epidemiology and Health Vol.29 No.1

  Experimental studies involve intervention and manipulation of study elements such as randomization of the participating groups. In general, experimental studies involving human are riskier than observational studies, demanding robust ethical vigilance and compliance among such stakeholders as investigators, sponsors, IRBs and health authorities. Social values of research should be counted as a primary ethical consideration in experimental research. It is unethical to put human subjects into uncertain and risky conditions if the study does not pursue valuable knowledge. Sound scientific design is prerequisite for good ethics. Risk-benefit ratio of the study must be carefully evaluated study. Not only risks from physical harms but also socio-economical and psychological harms from the study should be considered as risk of the study. Risks from the design of the study such as randomization and placebo must be carefully examined. Voluntary informed consent is essential in experimental studies involving human. Human subjects, before they decide to participate in the study, must be informed the followings: risks, benefits, experimental procedures, alternative treatment, compensation for injury, and participants" voluntariness and right to withdraw at anytime. Experimental studies are usually required written consent documentation and full institutional review board (IRB) review. Other elements of experimental research ethics includes special protection for high risk groups and various vulnerable groups, and protection of privacy and confidentiality.

납세자의 세무신고의사결정에 영향을 미치는 경제적․비경제적 요인에 대한 연구동향-실험연구를 중심으로-

배수진,심태섭 한국세무학회 2011 세무와 회계저널 Vol.12 No.3

실험연구는 행동회계연구에서 납세자의 조세순응 연구에 적절한 연구방법으로 고려되고 있다. 이에 본 연구에서는 기존의 행동회계연구에서 실험연구를 통해 제시된 납세자의 세무신고의사결정에 영향을 미칠 수 있는 다양한 요인들을 경제적 요인과 비경제적 요인으로 분류하여 제시하고, 각 요인에 속하는 연구들의 주제 및 설계 등을 검토하여 정리하였다. 그리고 이를 바탕으로 실험연구를 이용한 조세순응연구 분야에서 향후 연구방향을 제시하였다. 본 연구에서 분류한 경제적 요인은 주로 납세자들의 세후가처분소득에 영향을 미칠 수 있는 경제적 인센티브와 관련된 변수를 의미하며, 조세 제도적 요인(제재, 세무행정 및 세무관련 정보, 보상, 및 조세시스템)과 개인의 경제상황 요인(소득수준과 소득원천)으로 분류하였다. 반면, 비경제적 요인은 납세자 개인의 판단과 의사결정에 영향을 줄 수 있는 개인적 요인(인구통계적 특성), 심리적 요인(태도 및 인지), 사회․문화적 요인(사회적 가치관, 윤리적 권고)으로 분류하였다. 이러한 분류에 의하여 기존연구를 검토한 결과, 본 연구에서 다음과 같이 미래연구방향을 제시하였다. 첫째, 경제적 요인에 해당하는 정책변수 중 기존연구에서는 특정 변수에 한정되어 연구가 이루어지고 있는 경향이 있다. 따라서 선행 연구에서 분석되지 않았으나, 현재 과세당국에서 시행하고 있거나 앞으로 도입할 수 있는 정책에 대한 연구가 이루어져야 한다. 예를 들면, 세무조사대상자 선정방식에 관한 연구, 세무조사와 관련된 정보량이나 정보 공개 방식이 다를 경우 납세자들의 반응을 검증하는 연구 혹은 세무조사 후납세자의 세무신고성향의 변화에 관한 연구 등은 과세당국의 세무조사대상자의 선정방법, 정보공개 혹은 사후관리 관련 정책에 의미 있는 시사점을 제시할 수 있다. 둘째, 최근 연구에서는 비경제적 요인의 중요성이 강조되고 있으며 특히 윤리적 권고에 대한 연구들이 꾸준히 이루어지고 있다. 만일 윤리적 권고가 조세순응에 영향을 미친다면 이러한 효과의 지속성에 관한 연구가 이루어질 필요가 있다. 셋째, 경제적 요인 간 상호작용, 비경제적 요인 간 상호작용, 그리고 경제적 요인과 비경제적 요인간의 상호작용에 관한 연구가 필요하다. 마지막으로 선행연구에서 제시된 조세순응에 유의적인 영향을 미치는 변수들을 통합적으로 고려하여, 보다 폭넓은 관점에서 납세의사결정에 대한 추가적인 연구가 이루어져야 할 것이다. In the tax compliance research, the experimental method has been considered appropriate method. This study presents various factors affecting taxpayers' tax reporting decisions that have been suggested from previous behavioral accounting research using experimental method, by classifying into two categories of economic factors and non-economic factors. And then this paper reviews the research subjects, designs and results of studies related to two categories of factors. Finally, this paper suggests the direction of future studies on the tax compliance research using experiment. The economic factors in this study mostly mean the economic incentive-related variables of affecting after tax disposable incomes, and include tax institutional factors(sanction, tax administration and tax-related information, rewards and tax system) and individual economic-environmental factors(income level and income source). On the other hand, the non-economic factors in this paper include personal factors(demographic characteristics), psychological factors(attitude and cognition), and social and cultural factors(social norm, moral suasion). The directions for future research by reviewing the precedent studies are as follows ;First, fiscal variables mainly included in economic variables are found to be studied by focusing on particular factors in previous studies. Accordingly, studies are required on the policies which were not analyzed in precedent studies but tax authority has adopted currently, or may adopt in future. For example, research on audit scheme, taxpayers' responses when information level or disclosure method is different, or changes of taxpayers' tax reporting decisions after audit. These studies may suggest meaningful implications for tax authority's policies on audit schemes, audit scheme disclosure and post control of audit. Second, recent studies emphasize importance of non-economic factors, In particular, many researchers have argued that tax morale can help explain the tax compliance, If the moral suasions influence tax compliance, the research on the persistence of the effect are required. Third, studies on action effects of inter-economic factors, inter-non-economic factors, and between economic factors and non-conomic factors are required. Finally, in comprehensive consideration of variables having meaningful effects to tax compliance suggested in previous paper, further studies on tax payment decisions on a wider viewpoint are required.

발달지체유아를 대상으로 한 심리운동 중재 집단실험연구의 메타분석

송미정 ( Song Mi-jung ) 대구대학교 특수교육재활과학연구소 2020 특수교육재활과학연구 Vol.59 No.4

본 연구의 목적은 집단실험연구방법으로 수행된 발달지체유아를 대상으로 한 심리운동 중재 효과크기에 대한 메타분석을 실시하여 선행연구의 객관성을 확보하고 향후 연구 방향성을 모색하는데 목적이 있다. 이를 위해 2008년부터 2020년 8월까지 국내 석·박사 학위 논문 및 학술지에 게재된 집단실험연구 논문의 전체효과크기(ES), 독립변인, 종속변인, 출판유형의 효과크기와 이질성에 대한 조절효과크기를 분석하였다. 그 결과 첫째, 발달지체유아의 심리운동 중재 집단실험연구 전체 효과크기는 2.06로 높게 나타났으며, 둘째, 독립변인의 효과크기는 심리운동적 신체활동이 4.24로 가장 높았으며, 종속변인의 전체 효과크기는 .8나타났다. 각 종속변인별로 살펴보면 다음과 같다. 신체 1.62, 사회·정서 3.31, 문제행동 3.26, 인지 1.21, 의사소통 2.25로 .8이상으로 효과가 큰 것으로 나타났다. 셋째, 출판유형은 전체 효과크기에 영향을 줄 정도는 아닌 것으로 개별연구 간 효과크기가 동질하지 않으므로 이질성은 높게 나타났다. 이와 같이 본 연구에서는 선행된 집단실험연구의 결과를 통합 분석하여 개별 연구들의 효과크기(ES)를 객관적으로 제시하였고, 향후 발달지체유아를 대상으로 한 심리운동 중재 실험연구의 중요성을 부각시켰으며 과학적 연구방향을 모색하였다. The purpose of this study is to present the objectivity of previous studies and to seek directions for future studies by conducting a meta-analysis on the magnitude of the psychomotor intervention effect for children with developmental delays performed by the group experimental research method. To this end, from 2008 to August 2020, we analyzed the total effect size of group experimental research studies published in domestic master's and doctoral thesis and academic journals. Also, the effect size of the independent variable, the effect size of the dependent variable, the effect size of the publication type, and the moderating effect size for heterogeneity were analyzed. As a result, first, the overall effect size of the psychomotor intervention group experimental study of children with developmental delays was high as 2.06 value. Second, the effect size of the independent variable was the highest as 4.24 in psychomotor physical activity, and the total effect size of the dependent variable was good as 0.8. The effect size values for each dependent variable are as follows. Social/emotional 3.31, problem behavior 3.26, communication 2.25, body 1.62, cognitive 1.21, all of which were higher than 0.8, so the effect was good. Third, publication type was not enough to affect the total effect size, and the heterogeneity was high because the effect size was not homogeneous between individual studies. In this way, this study objectively presented the effect size of meta analyzing through previous group experimental studies utilizing psychomotor interventions. In addition, the importance of experimental studies on psychomotor interventions for children with developmental delays was highlighted, and scientific research directions were sought.

읽기 유창성 관련 실험연구 문헌 분석 - 2001년 ~ 2011년 국내 연구 중심으로 -

김태강 ( Tae Gang Kim ),정은희 ( Eun Hee Jeong ),박윤 ( Youn Park ) 대구대학교 한국특수교육문제연구소 2011 특수교육저널 : 이론과 실천 Vol.12 No.3

The purpose of this study was to analyze the trends of reading fluency-related experimental studies in Korea for 10 years and how they met the qualitative standards of scientific research. For literature analysis, literatures were searched and collected by domestic digital DB. For an analysis framework, single-subject design studies referred to Horner et al., (2005)’s quality indicators and Lee SH et al., (2005) and group experimental studies used Heo YS et al., (2010) who reconstructed Gersten et al., (2005)’s quality indicators. The results of this study were as follows: first, a total of 21 domestic reading fluency-related experimental studies were examined with 12 of single-subject design studies and 9 of group experimental studies and most of them were for elementary students. Since independent factors of all experimental studies but two used different intervention, it was difficult to suggest what intervention strategy was the most effective. Second, while the single-subject design studies was relatively high in qualitative indicators satisfaction, independent factor fidelity, inter-observer agreement, reliability, and replicable baseline description was limited. Finally, most group experimental studies did not meet a qualitative indicators. In particular, information on subjects, intervention fidelity, comparison group, intervention performer, and instrument validity was not sufficient. These results will contribute to providing the standards for selecting evidence-based instruction by helping improve elements which should be considered in further experimental studies.

길찾기 과정에서 랜드마크의 시각적·심리적 요소에 관한 연구

정진우 한국공간디자인학회 2019 한국공간디자인학회논문집 Vol.14 No.1

(Background and Purpose) The elements of landmarks that play an important role in wayfinding are visibility and identification, and in order to design efficient wayfinding methods, it is necessary to clarify the visual / psychological properties of landmarks. The purpose of this study is to measure the visibility and identification of landmarks in various experimental conditions using eye-tracking technology and computer simulation, and to reveal the complex relationship between these properties and wayfinding behavior to present the conditions of landmarks for effective wayfinding. (Method) In this study, we set the scope of the research focusing on the visibility and the identity of the landmarks, which is a descriptive variable of the research topic. This explains how the visual and psychological properties of the landmarks affect the identity and visibility of the landmarks. For the hypothesis test, four experiments were made by advancing-color(a), receding-color(r), familiarity(f), and unfamiliarity(u), and subjects were assigned to each experiment. The subjects read the instructions of the assigned experimental conditions, and after wearing the eye-tracker, they performed the task of selecting the objects specified in the computer simulation of the experimental conditions assigned. During the experiment, the subjects were properly selected and the time of object selection was recorded for the identification of the landmarks, and the subject's pupil movement was recorded for the visibility analysis of the landmarks. (Results) The results of the study are as follows. First, the age and sex of the subjects did not significantly affect the response variables of the study. Second, the visual and psychological factors of the landmarks did not significantly affect the accuracy of the landmarks selection. Third, the visual factor of the landmarks shows a slight difference in the promptness of the landmarks selection, but it is not statistically significant. Fourth, landmarks's psychological factors showed significant differences in the speed of landmarks selection and statistically tested. Fifth, in the experiment on visibility, it was found that both the position of the object and the visual / psychological factors have a significant effect on the visibility of the landmarks. (Conclusions) In order to improve the visibility and identification of the landmarks, this study has developed the direction of the landmarks design that the landmarks should be designed using the familiar objects and the color should be differentiated from the surrounding environments. The significance of this study is first, to provide the basis for designing a landmarks for effective wayfinding and secondly, to provide the researchers studying design various analysis methods and suggest ways to apply them to design. Experimental errors caused by limitations of experimental control in this study were derived as research problems through discussion. These research problems should be reflected in the experimental design of future research. (연구배경 및 목적) 도시의 길찾기에서 중요한 역할을 하는 랜드마크의 속성은 가시성과 식별성이고, 효율적인 길찾기 방법을 설계하기 위해서는 랜드마크의 시각적 / 심리적 속성을 밝힐 필요가 있다. 본 연구는 시선추적 기술과 컴퓨터 시뮬레이션을 이용하여 다양한 실험조건에서 랜드마크의 가시성과 식별성을 측정하고 그러한 속성들과 길찾기 행위와의 복합적 관계를 밝혀 효과적인 길찾기를 위한 랜드마크의 조건을 제시하는데 그 목적을 둔다. (연구방법) 본 연구에서는 연구주제의 설명변수인 랜드마크의 가시성과 식별성을 중심으로 연구의 범위를 정한다. 이는 랜드마크의 시각적 속성과 심리적 속성이 어떻게 랜드마크의 길찾기 역할인 식별성과 가시성에 영향을 미치는가를 밝히려는 것이다. 연구가설을 검정하기 위해 컴퓨터 시뮬레이션과 시선추적 실험이 준비되었다. 가설검정을 위해 진출색(a), 후퇴색(r), 익숙함(f), 익숙치 않음(u)을 조합하여 4가지의 실험을 만들고 피험자를 배정하였다. 피험자는 배정된 실험조건의 지시문을 읽고 시선추적기를 착용한 후에 배정된 실험조건의 컴퓨터 시뮬레이션에서 지정된 물체를 선택하는 작업을 수행하였다. 실험이 진행되는 동안, 피험자가 제대로 물체를 선택하였는가와 물체 선택 시간이 랜드마크의 식별성 분석을 위해 기록되었고, 피험자의 눈동자의 움직임이 랜드마크의 가시성 분석을 위해 기록되었다. (결과) 연구의 결과는 다음과 같다. 첫째, 피험자의 나이, 성별 등은 연구의 반응변수에 유의적인 영향을 주지 못하였다. 둘째, 랜드마크의 시각적, 심리적 요인은 반응변수인 랜드마크 선택의 정확성에 유의적인 영향을 주지 못하였다. 셋째, 랜드마크의 시각적 요인은 반응변수인 랜드마크 선택의 신속성에 약간의 차이를 보여주고 있으나, 통계적으로 유의한 결과는 아니었다. 넷째, 랜드마크의 심리적 요인은 랜드마크 선택의 신속성에 유의한 차이를 보여주고 있으며, 통계적으로 검정 되었다. 다섯째, 가시성에 대한 실험에서는 물체의 위치 및 시각적/심리적 요인 모두 랜드마크의 가시성(선주시)에 유의미적인 영향을 준다는 사실이 발견되었다. (결론) 본 연구는 랜드마크의 가시성과 식별성을 향상시키기 위해, 사용자에게 친숙한 사물을 이용하여 랜드마크를 설계해야 한다는 것과 주변환경과 차별되는 진출색을 가지고 있어야 한다는 랜드마크 설계 방향을 도출하였다. 본 연구의 의의는 첫째, 효과적인 길찾기를 위한 랜드마크 설계를 위한 기초를 제공한다는 것과 두 번째로, 디자인을 공부하는 연구자들에게 디자인 대상물에 대한 다양한 분석방법을 소개하고 디자인에 적용할 수 있는 방법을 제안한다는 것이다. 본 연구의 실험 통제의 한계로 발생된 실험오류들이 논의를 통해 연구문제로 도출되었고 이러한 연구문제들은 차후 연구의 실험설계에서 학문적으로 전개되어 반영되어야 한다.

공간 환경을 위한 EEG 실험에 의한 순색(pure color) 반응에 관한 연구

신동준 ( Dongjun Shin ),김주연 ( Jooyun Kim ) 한국공간디자인학회 2017 한국공간디자인학회논문집 Vol.12 No.5

(Background and Purpose) In modern living spaces, many color environments are being changed by several purposes, and space is created, and color is applied in consideration of a better color environment. In this context, interest in the color of space has rapidly increased, and consideration of a healthy spatial environment is a very natural consequence. Therefore, this paper studies the unexplored area of physiological aspects of pure color and its effect on spatial design, through the observation of response characteristics collected from an EEG experiment. Therefore, this is a very important study that can be used as a basis for future research through EEG experiments, which is a method for assessing emotions or evaluating cognitive responses by the unconscious level of human cognitive activity through brain response to pure color. (Method) This study analyzed and summarized the characteristics of the experiment, with a focus on the stimulus color, as to how the human brainwaves respond to pure color. The experiment was carried out for 32 subjects. In the experiment, pure color presented in the NCS (Natural Color System) was divided into eight stages and stimulated by color codes. (Result) In particular, the objective EEG instrument, certified at national level was, used to derive objective experimental results, and objective test results were derived by combining the experimental results and analyzing them with a significance probability of SPSS 22.0, a statistical verification step. Especially, in the experimental environment and conditions, EEG response of the physiological aspects to the pure color response was summarized by reducing experimental errors affecting the environment of experimental space, selecting objective subjects, and using the experimental method of applying VR for direct color stimulation. (Conclusion) Summarizing the results with the probability of significance of p<0.05 in the indicators of RAB and SEF50 that can determine the distribution of arousal and relaxation in the experimental results, the arousal distribution with high brain activity was high in RAB in Y, R; and the overall arousal distribution was shown in RAB in Y50R. Also in R50B, B, G, and G50Y, there was a lot of the distribution of relaxation in RAB, and the change in increasing brain activity was shown in B50G and G50Y. These results showed that warm colors do not awaken the brain unconditionally, and cold colors do not cause unconditional relaxation. Also, the contents of each color code of pure color were presented.

한약(韓藥)을 이용(利用)한 항암(抗癌) 실험연구(實驗硏究)의 경향(傾向)에 관(關)한 고찰(考察)

김현아,임성우,이원철,Kim, Hyung-A,Lim, Sung-Woo,Lee, Won-Chul 대한암한의학회 1998 大韓癌韓醫學會誌 Vol.4 No.1

Because there were lots of side effects and tolerances to the existing anticancer therapeutics, the experiment extracting the anticancer effect from medicinal herbs is in progress liviely. Therefore the purpose of this study were to research the tendency and the course of anticancer studies. To research the tendency of anticancer studies, medicinal herbs of fifty three experimental papers were analyzed and to examine the course of studies, anticancer papers in the medical world were used. The obtained results were as follows: Methods of herbal medicinal treatments were elimination the pathogenic factor(祛邪) and supporting healthy energy(扶正) method used. In this study, immediately tumor bearing and immune response were the most important point. The subject of immediately tumor bearing was not in the specific cancer but in the influence on the life span of general cencerous cells. In the experimental study of immune response, the effect on NK cell activity of medicinal herbs most studied. The combined usage of medicinal herbs and anticancer agent mostly intended to know whether it inhibits the tumor cell growth. The serum test and blood cell number test show if medicinal herbs inhibit side effect of anticancer agent. More than 80 percents of used medicinal herbs, there were anticancer activities. However anticancer experimental studies using medicinal herbs two weak points. The one, it was difficult to choose a prescription according to differentiation of symptoms and signs(辨證論) of the Oriental Medicine, because we put to the test not a man but a mouse. The other, as we observed the indirect effect of the whole physiological regulation caused by synergic effects of the complex prescription, we don't understand the detailed mechanism of the herb. Therefore, if the anticancer effect of the herb is proved the experiment, we should research the concrete medical action of medicinal herbs and immunological analysis of herbal medicines to the body.

장애 유아를 위한 음악활동 중재 연구 동향 분석 -2000~2007년까지의 국내 실험연구를 중심으로-

원종례,주용수 한국유아특수교육학회 2008 유아특수교육연구 Vol.8 No.1

This study reviews experimental research on music education programs for Preschoolers with disabilities in order to examine the current trends in research methods, contexts, and findings of the studies. A total of 55 experimental studies published between 2000 and 2007 are chosen. The review indicates that the number of participants in most studies is less than three, and most of the subjects are autistic 1-3 years old children. In most cases, the researchers participate in the intervention activities that focus on music therapy for individual children. The studies generally aim toward reduction of behavior problems and toward social, cognitive, and language development. More studies are conducted with single subject design within laboratory settings rather than natural classroom contexts. Drawing on the literature, the authors suggest some future directions for the research in the area. 본 연구는 국내의 유아특수교육 분야에서 2000년부터 2007년까지 실시된 음악활동 프로그램의 적용효과를 검증한 실험연구들을 중심으로 장애 유아의 음악활동 중재의 연구 동향을 분석하였다. 선정기준에 따라, 실험논문 55편을 연구대상자의 일반적인 특성과 중재 관련 특성으로 구분하여 분석한 결과, 연구대상자의 분석에서는 대상자 3명 이하, 1-3세 연령의 유아, 자폐성장애 유아를 대상으로 한 연구가 많았다. 중재관련 분석에서는 중재자가 주로 연구자들이었으며, 중재 장소는 일과 활동이 일어나는 자연스런 수업상황이 아닌 분리된 치료실에서 주로 이루어졌다. 중재집단은 개별 유아를 주 대상으로 하였고, 중재방법은 음악치료 및 교수전략이 삽입된 음악활동 프로그램을 중심으로 이루어졌으며, 목표행동은 장애 유아의 사회성, 인지, 언어 발달과 문제행동의 감소를 목표로 하였다. 실험설계방법은 단일대상연구 방법을 주로 사용하였으며, 자료는 빈도와 비율, 그래프로 제시하였다. 중재효과는 분석대상 모든 논문에서 검증을 했고, 유지효과는 23편의 논문에서 검증한 것에 비해, 일반화 검증은 극히 낮은 수준인 3편에서만 나타났다. 이러한 결과에 근거하여, 본 연구는 장애 유아의 음악활동 중재 관련 연구의 방향을 논의했다. 앞으로는 통합교육환경에서 실시되는 다양한 형태의 음악활동 프로그램을 확인하고 타당도와 충실도를 갖춘 프로그램을 개발하여 그 효과를 분석하는 연구가 필요하다.

임상기반 간호학 실험논문의 질 평가

정재심(Jeong, Jae Sim),임경춘(Lim, Kyung Choon),권정순(Kwon, Jeong Soon),곽찬영(Kwak, Chan Yeong),김경희(Kim, Kyung Hee),김성재(Kim, Sung Jae),이경숙(Lee, Kyung-Sook),박광옥(Park, Kwang Ok),김주현(Kim, Joo Hun),김금순(Kim, Keum So 한국근거기반간호학회 2018 근거와 간호 Vol.6 No.1

Purpose: This study was conducted in order to explore quality assessment tools applicable to research in the nursing area and to suggest the results of applying such tools in assessing the quality of experimental studies in nursing. Methods: We selected three experimental and 119 quasi-experimental studies with control groups in the Journal of Korean Clinical Nursing Research. We applied Cochran collaboration’s tool for assessing the quality of randomized controlled studies. Also, items developed by researchers were applied for assessing the quality of experimental studies in nursing. Results: Three studies (2.5%) used an adequate randomized sequence generation and two of them concealed the allocation sequence. The 63.1% of the studies applied blinding and 51% of the studies did not have missing values, or had insignificant missing values. In addition, 85.2% were not likely to report selectively, and 36.1% were assessed to have raised the risk of bias. Conclusion: Many studies had too a high risk of bias to be used as evidence-based data in the designs and methods of experimental studies. We found that it is necessary to inquire into research designs, methods, and quality assessment tools desirable for evidence-based practice in nursing.

韓藥을 利用한 抗癌 實驗硏究의 傾向에 關한 考察

金賢兒,林成祐,李源哲 대한한방종양학회 1998 대한한방종양학회지 Vol.4 No.1

Because there were lots of side effects and tolerances to the existing anticancer therapeutics, the experiment extraction the anticancer effct from medicinal herbs is in progress lively. Therefore the purpose of this study were to research the tendency and the course of anticancer studies. To research the tendency of anticancer studies, medicinal herbs of fifty three experimental papers were analyzed and to examine the coures of studies, anticancer papers in the medical world were used. The obtained results were as follows Methods of herbal medicinal treatments were elirmination the pathogenic factor(祛邪 ) and supporting healthy energy(扶正) method used. In this study. immediately tumor bearing and immune response were the most important point. The subject of immediately tumor bearing was not in the specific cancer but in the influence on the life span of general cancerous cells. In the experimental study of immume response, the effect on NK cell activity of medicinal herbs most studied. The combined usage of medicinal herbs and anticaner agent mostly intended to know whether it inhibits the tumor cell growth. The serum test and blood cell nunber test show if medicinal herbs inhibit side effect of anticancer agcnt. More than 80 percents of used medicinal herbs, there were anticancer activities. However anticancer experimental studies using medicinal herbs have two weak points. The one, it was difficult to choose a prescription according to differentiation of symptoms and signs(辨證論) of the Oriental Medicine, because we put to the test not a man but a mouse. The other, as we obseved the indirect effect of the whole physiological regulation caused by synergic effects of the compex prescription, we don't undersstand the detailed mechanism of the herb. Therefore, if the anticancer effect of the herb is proved the experiment, we should research the concrete medical action of medicinal herbs and immunological analysis of herbal medicines to the body.