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- 주제어 : Rete ridge (검색결과 3 건)
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구강내 점막과 유리피판에 사용되는 피부의 rete ridge에 관한 2차원 및 3차원적 구조 연구
안강민(Kang-Min Ahn),정헌종(Hun-Jong Chung),김윤태(Yoon-Tae Kim),팽준영(Jun-Young Paeng),신영민(Young-Min Shin),성미애(Mi-Ae Sung),박희정(Hee-Jung Park),명훈(Hoon Myoung),황순정(Soon-Jung Hwang),최진영(Jin-Young Choi),정필훈(Pill-Ho 대한구강악안면외과학회 2005 대한구강악안면외과학회지 Vol.31 No.2
Objects : With the advancement of tissue engineering techniques, the effort to develop bioartificial mucosa have been actively delivered. The problem we met with this technique is the lack of mechanical strength between kerationocyte layer and dermal layer, where in the normal skin and mucosa, they are tightly bound with rete ridge structure. The purpose of this study is to understand the 2D and 3D structure of rete ridge of mucosa and skin paddle for rendering more biomimetic structure to the artificial mucosa. Materials and Methods : Oral mucosa and skin from the patients who received the oral surgery and maxillofacial reconstruction were harvested. The epidermis was separated from the dermis after treating with dispase for 12-16 hours. H & E staining was performed for 2D(dimensional) structure study and confocal LASER and SEM study were performed for 3D structure. Mean height(Sc) and arithmetic mean deviation(Sa) of all surface height were calculated. Results : The average height of rete ridge of skin flap was between 67.14㎛ and 194.55㎛. That of oral mucosa was between 146.26㎛ and 167.51㎛. Pressure bearing area and attached gingiva of oral mucosa showed deeper rete ridges. Conclusion : To obtain the adequate strength of artificially cultured keratinocyte skin and mucosa flap, it is necessary to imitate the original skin and mucosa structure, especially rete ridge. Through this study, 2D and 3D rete ridge structure of normal mucosa and skin was obtained. These results can be used as basis for substrate morphology for keratinocytes culture.
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이애영(Ai Young Lee),이유신(Yoo Shin Lee) 대한피부과학회 1989 대한피부과학회지 Vol.27 No.2
Lesional and normal skins in 10 patients of fixed drug eruption were studied. Number and vertical distance of rete ridges were measured in H & E stained specimens. Amount of free melanin and number of melanocytes were counted in dopa stained epidermal sheets. According to the number of recurrence, activity and number of melanocytes see med to be changed. The lesions of a few recurrence showed only active melano cytes, however, those of frequent recurrenoe increased number of melanocytes with marked elongation of rete ridges. It is supposed that the numerical increase of melanocytes were from the elongation of rete redges,
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이일주(Il Joo Lee),전수일(Soo Il Chun) 대한피부과학회 1993 大韓皮膚科學會誌 Vol.31 No.4
Background : Beckers nevus is a benign lesion that may be congental or acquired, macular or papular, hairless or hypertrichotie. Objective : Our pcrpose was to describe the clinical findings of Eeckers nevus and to establish a method for the histologic diagnosis of Beckers nevus. Methods : We reviewed PF skin biopsies and their clinical finding from 28 patients with Beckers nevus during a 10 year period from January 1981 to January 1991. Results : The results were summarized as follows. A Clinical characteristics 1. Sex distribution showed of male predominence with male female a ratio of 1.5:1. Age of onset was predominent in less that 5 years old and puberty. 2. The lesions were located on the trunk(24 cases), head & neck(8 cases), extremities(6 cases), and were repsilateral in 26 cases, bilateral in 2 cases. 3. The lesions were accompanied by hair in 17 cases(61%). The shaies of the lesions were reticulated (75 %), patch(18%), mottled(7%). 4. Hairs were distributed as follows : abdomen(100%), scapula(100 %), extremities (83%), cheek(80 %), neck(67 %), chest(40%). All lesions of the face had follicular papules. 5. Associated skin diseases were : smooth muscle hamartoma(3 cases), striae distensa(2 cases), steroid acne(2 cases), pigmented nevus(2 cases), and verruca plana(1 case). B. Histopathologic characteristics 1. The lesions were accompanied with plugs in 21 cases, which were follicular, acrosyringeal, epidermal. 2. Elongation of the rete ridge and hyperpigmented basal cells were observed in the epidermis in all cases. 3. The shape of the rete ridge in Beckers nevus has its characteristic appearance, which is single, bridging and reticulated. Single, bridging and reticulated shapes cexisted in 17 cases(61%). 4. Inflammatiry cell infiltrations were present in all of the upper drmis, in which melanophages(21 %), hair follicles(89%) and smooth muscle hamartoma(3cases) w ere observed Conclusion : These findings indicated that the shape of the rete ridge in Beckers nevus has its characteristic appesrance and can be useful for the diagnosis of Beckers nevus. (Kor J Dermatol laa3;31(4):539-547)
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