The gas separation properties of the hydrocarbon based polymeric membrane containg glassy poly(ethylene glycol)

송미애,김득주,남상용 한국공업화학회 2014 한국공업화학회 연구논문 초록집 Vol.2014 No.1

본 연구에서는 Polysulfone에 Polyethylene glycol을 graft하여 합성하였다. 고분자량의 결정성을 가지는 Poly ethylene glycol(Mw= 2000 and 5000)을 사용하여 합성된 Polysulfone-graft-poly(ethylene glycol) 공중합체와 Polysulfone 고분자를 비교했을 때 높은 CO₂ 기체투과선택도 특성을 나타내는지에 대해 알아보았다. TGA와 DSC로 고분자의 graft 유무를 확인하고, FT-IR 과 ¹H-NMR을 이용하여 화학구조를 분석하였다. Time lag 기계를 사용하여 Film의 기체투과 성능을 조사하였으며, Poly(ethylene glycol)의 분자량에 따른 효과를 알아보았다.

The gas separation properties of the hydrocarbon based polymeric membrane containing glassy poly(ethylene glycol)

송미애,김득주,남상용 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.1

본 연구에서는 Polysulfone에 Polyethylene glycol을 graft하여 합성하였다. 고분자량의 결정성을 가지는 Poly ethylene glycol(Mw= 2000 and 5000)을 사용하여 합성된 Polysulfone-graft-poly(ethylene glycol) 공중합체와 Polysulfone 고분자를 비교했을 때 높은 이산화탄소 기체투과선택도 특성을 나타내는지에 대해 알아보았다. TGA와 DSC로 고분자의 graft 유무를 확인하고, FT-IR과 1H-NMR을 이용하여 화학구조를 분석하였다. Time lag 기계를 사용하여 Film의 기체투과 성능을 조사하였으며, Poly(ethylene glycol)의 분자량에 따른 효과를 알아보았다.

Degradation of poly(ethylene glycol-propylene glycol) copolymer and its influences on copper electrodeposition

Choe, S.,Kim, M.J.,Kim, H.C.,Lim, T.,Park, K.J.,Kim, K.H.,Ahn, S.H.,Lee, A.,Kim, S.K.,Kim, J.J. Elsevier Sequoia 2014 Journal of Electroanalytical Chemistry Vol.714 No.-

In this work, the degradation of poly(ethylene glycol-propylene glycol) copolymer (PEG-PPG) and its effect on the electrodeposition of Cu were investigated. PEG-PPG became fragmented during the electrodeposition with changing its terminal groups from hydroxyl to aldehyde, formic ester, and ketone. The aged solution showed a higher saturation current density than the fresh solution in chronoamperometry (CA) measurements, resulting from an easier desorption of the cleaved PEG-PPG from the copper surface through the competition with bis-(3-sulfopropyl)-disulfide (SPS). Furthermore, the electrical resistivity of Cu films deposited from the aged solution increased due to a decrease in the grain sizes.

Spectroscopic study on the intermolecular interaction of SO2 absorption in poly-ethylene glycol+H2O systems

Zhiqiang He,Jinrong Liu,Jianbin Zhang,Na Zhang 한국화학공학회 2014 Korean Journal of Chemical Engineering Vol.31 No.3

Poly-Ethylene Glycol (PEG) 300+H2O solutions (PEGWs) has been used as a promising medium for theabsorption of SO2. We investigated the UV, FTIR, 1H-NMR, and fluorescence spectra in the absorption processes ofSO2 in PEGWs to present an important absorption mechanism. Based on the spectral results, the possibility of intermolecularhydrogen bond formation by hydroxyl oxygen atom in the PEG molecule with hydrogen atom in H2O andS…O interaction formation by the oxygen atoms in PEG with the sulfur atom in SO2 are discussed. This shows thatthe spectral changes may be due to the formation of -CH2CH2O(H)…HOH… and -CH2-CH2-O(CH2-CH2-)…HOH…in PEGWs and the formation of -CH2CH2OH…OSO…, and intermolecular S…O interaction between PEG and SO2as the formation of -CH2CH2OCH2CH2O(H)…(O)S(O)… and -CH2-CH2-O(CH2-CH2-)…(O)S(O)…. The existenceof these bonds benefits the absorption and desorption processes of SO2 in PEGWs.

N-vinylcaprolactam-based temperature and pH-sensitive graft hydrogels for controlled drug release of 5-FU: a comprehensive study on synthesis, characterization, and release kinetics

İ. K. Akbay,T. Özdemir 한국고분자학회 2024 Macromolecular Research Vol.32 No.3

Stimuli-responsive polymers can be used for various purposes due to their amazing properties within the context of controlled release systems. In this study, the aim was to prepare hydrogels that are stimulus-responsive to temperature and pH and utilize them in drug release investigations. N-Vinyl caprolactam-based polymers were synthesized and optimized based on the swelling ratio data. Both temperature and pH sensitivity, along with their respective transition values, were determined. The best sample was selected based on 5-FU encapsulation efficiency. To enhance the swelling ratio and encapsulation values, different amounts of poly-(ethylene glycol) were added to improve water swelling ratio and 5-FU release properties. All obtained samples were characterized using water swelling ratio, SEM, FTIR, and DSC analyses. Additionally, the encapsulation and release of the 5-FU drug from the hydrogels were studied. According to the results, it was understood that it could release the 5-FU drug approximately 14% when below the transition temperature and pH value, and approximately 99% when above the transition temperature and pH value. The kinetics of the drug release were thoroughly examined. The results of thekinetic study revealed a drug release pattern consistent with Fick's law.

Poly(ethylene glycol) (PEG) Microwells in Microfluidics: Fabrication Methods and Applications

강도현,서갑양,김필남,Hong Nam Kim 한국바이오칩학회 2014 BioChip Journal Vol.8 No.4

Immobilization of bioanalytes (e.g., protein,lipid membrane, and cells) within a microfludic chan-nel is a useful strategy in diverse biological analysisincluding biosensor, diagnosis, and biochemical reac-tions. Such microfluidic systems can offer miniaturiz-ed platforms with distinct advantages such as reduceduse of samples or reagents and increased resolution. Inparticular, polymeric microfluidic devices (e.g., poly-dimethylsiloxane (PDMS)) bound to a substrate havebeen widely used. However the non-specific adsorp-tion of bioanalytes is serious problem for microfluidicbiological assays, especially for dilute samples. Toovercome such limitations, a simple and widely applic-able microfluidic channels combined with polyethyl-ene glycol (PEG) microwells have been developed. Inthis review, we summarize the methods and applicationof PEG microwells with a particular emphasis on inte-grated microfluidic systems. The assembly betweenPEG microwell and microchannel enables precise de-livery and manipulation of the biosamples, leading todevelopment of miniaturized diagnostic assays, micro-reactors, and multiple screening platforms for tissueengineering and cell biology.

Self-Assembled Polymeric Nanoparticles of Poly(ethylene glycol) Grafted Pullulan Acetate as a Novel Drug Carrier

Sun-Woong Jung,Young-Il Jeong,Young-Hoon Kim,Sung-Ho Kim 대한약학회 2004 Archives of Pharmacal Research Vol.27 No.5

Self-assembling nanospheres of hydrophobized pullulan have been developed. Pullulan acetate (PA), as hydrophobized pullulan, was synthesized by acetylation. Carboxymethylated poly(ethylene-glycol) (CMPEG) was introduced into pullulan acetate (PA) through a coupling reaction using N,N'-dicyclohexyl carbodiimide (DCC). A synthesized PA-PEG-PA (abbreviated as PEP) conjugate was confirmed by Fourier transform-infrared (FT-IR) spectroscopy. Since PEP conjugates have amphiphilic characteristics in aqueous solution, polymeric nanoparticles of PEP conjugates were prepared using a simple dialysis method in water. From the analysis of fluorescence excitation spectra primarily, the critical association concentration (CAC) of this conjugate was found to be 0.0063 g/L. Observations by scanning electron microscopy (SEM) showed the spherical morphologies of the PEP nanoparticles. The particle size distribution of the PEP conjugates was determined using photon correlation spectroscopy (PCS) and the intensity-average particle size was 193.3 ± 13.53 nm with a unimodal distribution. Clonazepam (CNZ), as a model drug, was easy to entrap into polymeric nanoparticles of the PEP conjugates. The drug release behavior was mainly diffusion controlled from the core portion.

Self-Assembled Polymeric Nanoparticles of Poly(ethylene glycol) Grafted Pullulan Acetate as a Novel Drug Carrier

Jung, Sun-Woong,Jeong, Young-Il,Kim, Young-Hoon,Kim, Sung-Ho The Pharmaceutical Society of Korea 2004 Archives of Pharmacal Research Vol.27 No.5

Self-assembling nanospheres of hydrophobized pullulan have been developed. Pullulan acetate (PA), as hydrophobized pullulan, was synthesized by acetylation. Carboxymethylated poly(ethylene-glycol) (CMPEG) was introduced into pullulan acetate (PA) through a coupling reaction using N, N'-dicyclohexyl carbodiimide (DCC). A synthesized PA-PEG-PA (abbreviated as PEP) conjugate was confirmed by Fourier transform-infrared (FT-IR) spectroscopy. Since PEP conjugates have amphiphilic characteristics in aqueous solution, polymeric nanoparticles of PEP conjugates were prepared using a simple dialysis method in water. From the analysis of fluorescence excitation spectra primarily, the critical association concentration (CAC) of this conjugate was found to be 0.0063 g/L. Observations by scanning electron microscopy (SEM) showed the spherical morphologies of the PEP nanoparticles. The particle size distribution of the PEP conjugates was determined using photon correlation spectroscopy (PCS) and the intensity-average particle size was 193.3 ${\pm}$ 13.53 nm with a unimodal distribution. Clonazepam (CNZ), as a model drug, was easy to entrap into polymeric nanoparticles of the PEP conjugates. The drug release behavior was mainly diffusion controlled from the core portion.

피톤치드를 함유한 마이크로캡슐 제조의 벽재물질의 영향

김효정,이유정,임용환,김배용,이철태 한국공업화학회 2015 한국공업화학회 연구논문 초록집 Vol.2015 No.0

피톤치드는 식물이 내는 항균성 물질의 총칭으로서, 살충, 살균, 탈취 등의 효과가 있어 여러 산업분야에서 다양한 활용이 기대되어지고 있다. 그러나 피톤치드는 휘발성이 강하여 그 작용이 오랜 시간 지속되지 못한다는 문제점이 있다. 때문에 피톤치드를 제품화하기 위해서는 유효성분의 방출속도를 조절할 수 있는 기술의 개발이 필수적이다. 본 연구에서는 피톤치드의 방출속도를 조절하기 위한 기술로서 마이크로캡슐화 방법을 선택하였고, 마이크로캡슐을 제조하기 위한 벽재물질을 Gelatin과 Poly-ethylene glycol를, 가교제로서는 Tanine acid와 Citric acid 를 사용하여 벽재물질의 함량, 가교제의 종류 및 함량, 교반속도를 변수로 하여 최적의 마이크로캡슐화 제조 조건을 연구하였다. 이후 Scanning Electron Microscope(SEM)을 통해 캡슐의 형상을 확인하였고, UV-Vis Spectrometer 을 이용하여 피톤치드의 유효성분에 대한 서방성을 확인하였다.

Rapid hydrophilic modification of poly(ethylene terephthalate) surface by using deep eutectic solvent and microwave irradiation

Cho, Jae Yeoun,Choi, Hyung-Min,Oh, Kyung Wha Sage Science Press 2016 Textile Research Journal Vol. No.

<P>Rapid hydrophilic modification of poly(ethylene terephthalate) (PET) fabric was carried out by deep eutectic solvent, ethylene glycol-choline chloride (EGC), under microwave irradiation. EGC is an inexpensive eco-friendly solvent, which is easy to handle along with low toxicity. Results showed that alkali concentration and microwave irradiation time were critical factors in determining surface characteristics of PET. The EGC-treated PET fabric showed highly hydrophobic surface with long wicking time (>2000 s) and high contact angle (135 degrees) at 60 s of microwave irradiation time. However, by merely adding 0.5% sodium hydroxide, the EGC-treated PET fabric surface was drastically changed to highly hydrophilic surface with instant wicking time. The structure of modified PET was studied by various instrumental analyses such as Fourier transform infrared spectroscopy, thermogravimetric analysis, differential scanning calorimetry, and scanning electron microscopy. Tensile strength and methylene blue staining tests were also carried out to determine characteristics of the modified PET fabrics.</P>