한의사 설문을 통한 미병관리의 제도적 활성화 방향 조사

문석희,이의재,류지선,임병묵 대한예방한의학회 2017 대한예방한의학회지 Vol.21 No.3

Objectives : This study aims to investigate the recognition on Mibyeong among Korean Medicine doctors (KMDs) and to suggest institutional approaches for the active use of Mibyeong. Methods : On-line survey for KMDs who were registered in the Association of Korean Medicine was performed. The survey questionnaires included definitions and categories of Mibyeong, clinical use of Mibyeong, and the need for developing Mibyeong care packages, etc. Results : Of 18,344 KMDs who were received survey e-mail, 884 KMDs replied. As for the awareness of the Mibyeong, over 80% of the KMDs agreed the definitions based on patients’ subjective symptoms and Korean Medicine theories. 36.1% of respondents used the term Mibyeong in the medical record, and 38.6% used when they explained the patients’ condition to the patients. A majority of respondents agreed with the need for a developing Mibyeong care package. Developing the standard methods for Mibyeong assessment was the primary requisite on Mibyeong research. Conclusions : Currently the level of recognition and use of Mibyeong among Korean Medicine doctors was relatively low. To promote the use of Mibyeong in the clinical field, the standard methods for Mibyeong assessment and Mibyeong care package need to be developed.

일반인의 미병 인식 변화 양상과 관리방안 조사

이은영,박기현,유종향,이시우,Lee, Eunyoung,Park, Kihyun,Yoo, Jonghyang,Lee, Siwoo 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

Objectives : The purposes of this study were to investigate the recognition of Mibyeong, symptom, management plan and correlation between quality of life and health condition, and to suggest a plan for managing Mibyeong status. Methods : Participants were recruited based on the same sampling methods used on the previous study performed in 2013 based on area, gender and age. Questionnaires were collected by Gallup Korea professional surveyor through face-to-face interviews. The questionnaires contain questions about the recognition of Mibyeong, symptom, management plan and the quality of life in accordance with the relevant health conditions. Descriptive statistics were used for data analysis and the results were expressed as percentage ratios (%). Results : 1,100 of people were acquired in 2015. The responses for "First time to hear of Mibyeong" have shown that the percentage were reduced from 80% to 67% compared with 2013 data. The ratio of Mibyeong's symptoms in 2015 were similar to 2013. we suggested some ways to deal with the Mibyeong status including behavior adjustment (non smoking, non alcohol, control sleep pattern), herbal tea, health functional food, exercise, preventive health care (qi-gong, yoga), meditation, home health care medical device (hot-pack, seat device for fumigation, massager), and medical service (hospital, medical clinic oriental medical clinic). Almost people showed that positive opinion with them. There were significant correlation between quality of life with the health status rather than Mibyeong or disease group. Conclusions : This study was performed through scientific questionnaires collected in 2013 and 2015 to investigate people's understanding of Mibyeong as a present condition in Korean public. Some questions had significantly different responds between both years while others showed similar trends for both years. These results suggest that the concept of Mibyeong in oriental medicine could provide a management mechanisms that help people to manage the Mibyeong status.

인터넷 상에서 사용되는 미병의 개념 및 사용자 분석 - 네이버 지식-iN과 카페를 중심으로 -

김선민,이시우,문수정,Kim, Sunmin,Lee, Siwoo,Mun, Sujeong 대한예방한의학회 2017 대한예방한의학회지 Vol.21 No.1

Objectives : Although interest in preventive medicine has increased recently, "Mibyeong", the preventive concept of Korean medicine, is still unfamiliar to the general public. Therefore, this study aims to investigate the concept of Mibyeong and users used on the Internet. Methods : Naver (www.naver.com), which has the highest ranking in terms of market share, number of visitors, search time share, and community category share, has been selected as a search target and jisik-iN Q&A and posts of cafe about Mibyeong were searched for recently approximately 6 years. Results : 105 cases of Jisik-iN Q&A and 283 cases of cafe posts were searched. Overall, the number of Jisik-iN Q&A and cafe posts's Mibyeong term usage was the highest in 2013. In the Internet user category, Mibyeong Term was used most commonly in the Jisik-iN Q&A by Korean medicine related medical personnel (29 cases, 28%) and in the cafe other health-related workers (87cases, 31%). In Mibyeong related cafe classification, Information Exchange (220 cases, 77%) was the most frequent and besides 39 cases (14%) used in Operation of Medical Institutions. And the concept of Mibyeong was often used as symptom-based rather than diagnostic test or disease (Cafe posts 52%, Jisik-iN Q&A 70%), in particular, topic of Mibyeong related Jisik-iN Q&A was used in the order of pain (31 cases, 16%), cancer (17 cases, 9%), fatigue (11 cases, 6%). Conclusions : This study has significance as basic research data of general Internet user group and can be used as fundamental data for awareness promotion, publicity and necessity of Mibyeong.

미병 특허 동향 조사

진희정,이영섭,유하나,이시우,Jin, Hee-Jeong,Lee, Youngseop,Yu, Hana,Lee, Siwoo 대한예방한의학회 2015 대한예방한의학회지 Vol.19 No.3

Objective : The purpose of this study was to analyze for the patent application tendency in mibyeong. Mibyeong is a concept in Korean Medicine meaning sub-health state, and treatment of mibyeong can be understood as preventive medicine. This concept laid a foundation for the development of Korean, Japanese and Chinese traditional medicine. In this paper, we describe a meaningful data for efficient R&D through patent analysis of mibyeong focusing on the Korea, Japan and China. Method : We collected patents about mibyeong using Focust, IPDL search tools. We analyzed patents according to the year, topic, country and etc. Results & Conclusion : We collected 1,577 patents and selected 807 patents as useful patents. After detailed analysis on mibyeong patent, we got to know that research about mibyeong was a growing field. In the collected patents, the patents on treatment device(except treatment compositions) were the majority and system of providing information were the second largest. We think that the mibyeong field is growing at a fast pace with high activity, and this research should be updated annually.

미병(未病)의 의학적 개념 정립을 위해 고려해야 할 주제들

남동현,한경숙,Nam, Donghyun,Han, Kyungsook 대한한의진단학회 2020 大韓韓醫診斷學會誌 Vol.24 No.1

Objectives Mibyeong is an ideological concept that means the state between the healthy and diseased conditions. The purpose of this study was to suggest a research direction to establish the diagnostic criteria for the Mibyeong by reviewing the research results for the Mibyeong. Methods Academic databases (OASIS for Korean database, Embase for English database, and CNKI for Chinese database) were used to search related literatures, and articles describing the concept or diagnostic criteria of the disease were selected. Results The concept of Mibyeong consisted of three different conditions: (1) subjective symptoms without a specific disease, (2) abnormal examination findings without a specific disease, and (3) a state in between health and disease. No matter which of the three conditions is applied, the spectrum of condition was very wide and diverse. Conclusions It is impossible to apply appropriate and monolithic diagnostic criteria to all types of Mibyeong. Therefore, we suggests that the Mibyeong be classified into several subtypes and the diagnostic criteria suitable for each type be established.

미병 정량 지표에 관한 중국의 임상연구 동향 분석 - China National Knowledge Infrastructure를 중심으로 -

여민경,이영섭,Yeo, Minkyung,Lee, Youngseop 대한예방한의학회 2018 대한예방한의학회지 Vol.22 No.1

Objectives : The purpose of this study was to analyze the trend of clinical research on quantitative indicators of Mibyeong in traditional chinese medicine(TCM). Method : The journal search was performed using china national knowledge infrastructure(CNKI) database. Our inclusion criteria were as following: TCM clinical researches for quantitative indicators of Mibyeong. Exclusion criteria were as following: non-TCM clinical researches, used intervention methods. Results : Eleven clinical researches were analyzed in this study. Four of these researches classify the Mibyeong as a type of pattern identification(PI) and studied the characteristics of the PI quantitative indicators. Mibyeong diagnosis was done through guidelines and questionnaires, each was used at a similar rate. Quantitative indicators mentioned in the selected researches were blood indices, nailfold capillary, complexion, color of tongue substance and coating, pulse wave diagrams and heart rate variability. Among them, seven researches related to blood indices were the most. Blood indicators include whole-blood viscosity, plasma viscosity, fibrinogen, packed cell volume(Hct), triglycerides, total cholesterol, HDL-C, LDL-C, glucose, BUN/CREA, luteinzing hormone, estradiol, follicle stimulating hormone, IgA, IgG, etc. Conclusions : Based on this results, in combination with western medicine, it seems necessary to try to interpret the Mibyeong in more various ways. Even if the same Mibyeong, it is necessary to identify the index which changes according to the PI or chief complaint, and to set the Mibyeong standard corresponding thereto.

피로형 미병에 대한 당귀보혈탕의 효과

박선행,성윤영,장설,이시우,김홍준,김호경,Park, Sun Haeng,Sung, Yoon-Young,Jang, Seol,Lee, Siwoo,Kim, Hong Jun,Kim, Ho Kyoung 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.3

Objectives : Mibyeong is a korea medicine have original concept of the disease. However, no previous report has effect of mibyeong herbal medicine in fatigue types of mibyeong. This study investigated the question of whether Dang Gui Bo Hyul-tang(DGBHT) of effect on fatigue types of Mibyeong. Methods : C57BL/6 mice were randomaly divided into three group (n=10). The mice were then group (1) Nocontrol, (2) Restraunt stress(veh), (3) Dang Gui Bo Hyul-tang 200mg/kg. The administered Dang Gui Bo Hyul-tang 200mg/kg or distilled water (orally) 1 hr prior to daily exposure to repeated restraint stress (2 h) for 15 days. The performed behavior test (Mechanical hyperalgesia test,, Open-field test, Forced swimming test, Sucrose preference test and immunostaining and biochemical measured in serum. Results : Stress fatigue induced mices significantly increased lethargic, hyperalgesia through behavior test (Mechanical hyperalgesia test (decrease 43%), Open-field test ($4,809{\pm} 226.13cm$ vs. $3121{\pm}226.64cm$), Forced swimming test ($11.45{\pm}3.96$ vs. $79.10{\pm}8.12sec$), Sucrose preference test (decrease 58%)). In addition, chronic fatigue model evidently increased corticosterone level ($122.54{\pm}18.88$ vs. $186.94{\pm}18.26ng/ml$), AST level ($46.22{\pm}3.23$ vs. $31.40{\pm}3.86U/L$), ALT level ($38.78{\pm}5.72$ vs. $17.60{\pm}1.30$), liver necrosis, lateral ventricle size. These alterations were significantly ameliorated by DGBHT. DGBHT significantly attend the elevated serum concentrations of corticosterone ($155.90{\pm}6.29ng/ml$), AST ($31.40{\pm}3.86U/L$), ALT ($17.60{\pm}1.30U/L$). Moreover, DGBHT improved lethargic, hyperalgesia when compared the stress fatigue (Mechanical hyperalgesia test (improve 28%), Open-field test ($4,038{\pm}615.81cm$), Forced swimming test ($7.56{\pm}1.88sec$), Sucrose preference test (increase 21%) Conclusions : Theses result suggest that DGBHT have improved lethargic, hyperalgesia and fatigue-associated hormone and liver protective on stress fatigue model. It will be necessary to research to present evidences on benefits and effects of Korean medical treatment for Mibyeong through clinical researches based on benefits and effects of those animal models.

미병 개념에 대한 小考

박영배(Young-Bae Park) 대한미병의학회 2020 대한미병의학회지 Vol.1 No.1

The terms and concepts of Mibyeong (Subhealth) were considered. Mibyeong is defined as ‘a health condition in which the purpose function of each organ is reduced due to mental and physical dysregulation’. ‘Purpose function’ refers to basic functions and inherent functions that each organ aims. The goal of Mibyeong is to improve performance over treatment. In the future, we need to conduct various in-depth research such as indicator development, measurement method, and evaluation method for performance measurement of Mibyeong.

미병에 대한 한국 일반인의 인식과 미병률 현황 : 전국조사

이은영,이영섭,박기현,유종향,이시우,Lee, Eunyoung,Lee, Youngseop,Park, Kihyun,Yoo, Jonghyang,Lee, Siwoo 대한예방한의학회 2015 대한예방한의학회지 Vol.19 No.3

Objectives : The purpose of this study was to reveal the prevalence of Mibyeong and its symptoms including fatigue, pain, sleep disturbance, dyspepsia, depression, anxiety and anger by using the national survey. Methods : Questionnaires were collected by Gallup Korea. Participants were chosen through stratified sampling method based on area, gender and age. Questionnaire was designated to confirm the recognition, managing of Mibyeong, investigation of life habit, medical history, basic information, QoL questionnaires (Short Form-12, EuroQol-5D) and understanding of Mibyeong medical service conditions. Generally all questionnaires were used for survey the Mibyeong status in public except QoL questionnaires. Questionnaires were fulfilled by professional surveyor as face to face interview. Descriptives was used for data analysis and the results were expressed as percentage ratios (%) Results : 1,101 of people were acquired in this study. Eighty point two (80.2%) percent of participants did not know the concept of Mibyeong accurately even though 80.6% complained of Mibyeong related symptoms. Among them, fatigue was accounted for the highest response (70.7%)in this study. Sixty point four percent of participants identified non-smoking, stop drinking, eating habits and sleeping habits as a way to manage their Mibyeong related symptoms. In addition, exercising (60.8%), visiting medical institution (58.4%) and taking health functional food (52.7%) were presented. Only 23.1% among people with symptoms Mibyeong visited medical facilities. Moreover, the quality of life was found to be significantly correlated with health status. Conclusions : This study could contribute to express the importance of announcing the concept of Mibyeong and status to Korean public. Moreover, more Mibyeong studies should be conducted in the future to evaluate the Mibyeong status objectively.

30-40대 여성의 미병상태에 따른 월경양상 비교연구

박민영,오현주,황민우 대한예방한의학회 2019 대한예방한의학회지 Vol.23 No.1

Introduction : The aim of this study was to investigate menstrual pattern according to Mibyeong Index(MBI) and compare Mibyeong symptom score according to severity of menstrual pain. Mibyeong Index was designed to measure inconvenience and resilience of subject’s complains including four physical symptoms(fatigue, pain, low sleep quality, indigestion) and mental distress including anxiety, anger, depression. Method : We used the clinical data of Korean medicine Date Center(KDC) for subjects who participated in the study of ‘Clinical research for collecting of clinical cases based on the personal type of Mibyeng’ conducted in Seoul, from June 26, 2015 to June 26, 2017. A total of 566 fertile women aged 30 to 50 who completed the questionnaires were included in this study. In this study, we used items of Mibyeong Index and the menstrual pattern by self-report questionnaires. The date were analyzed through Kruskal Wallis test, Pearson's chi-square test, and one-way ANOVA using SPSS statistics 19.0. Results : Mibyeong status was significantly associated with severity of menstrual pain(p<0.001), worst day of menstrual pain(p<0.05), and type of menstrual pain(low back pain, nausea, depression, and none (respectively, p<0.05)). In addition, The 7-subtype score (fatigue (p<0.001), pain(p<0.001), low sleep quality(p<0.001), indigestion(p<0.001), anxiety(p<0.05), anger(p<0.05) and depression(p<0.05)) of Mibyeong index and total score of Mibyeong Index (p<0.001) showed significant difference for severity of menstrual pain. Conclusion : This result indicates that a close relationship between Mibyeong status and severity of menstrual pain. Further studies are needed but, we hope that this results will be used as the basic data to improve mibyeong status through health care to alleviate dysmenorrhea.