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      • Effects of Acute Pre-Workout Dietary Supplement Ingestion With and Without Synephrine on Serum Creatine

        ( Yp Jung ),( M Koozehchian ),( R Dalton ),( C Rasmussen ),( P Murano ),( Cp Earnest ),( Rb Kreider ) 한국체육학회 2016 국제스포츠과학 학술대회 Vol.2016 No.1

        Purpose: A number of nutritional strategies have been developed to optimize nutrient delivery prior to exercise. As a result, various pre-workout supplements have been developed to increase energy availability, promote vasodilation, and/or positively affect exercise capacity. The purpose of this study was to examine the effects of acute pre-workout dietary supplement ingestion with and without synephrine on serum creatine in healthy, active volunteers. Method: We randomized 25 apparently healthy and recreationally active men (n=20) and women (n=5) (21.76±3.00 yr, 15.24±5.26% fat, 25.09±3.03 kg/m2) in a double-blind, crossover, randomized and placebo- controlled manner to acutely ingest (1) a dextrose flavored placebo (PLA); (2) a pre-workout supplement (PWS) containing 3 g beta alanine, 2 g creatine nitrate, 2 g arginine AKG, 300 mg N-acetyl tyrosine, 270 mg caffeine, 15 mg Mucuna pruriens; or, (3) PWS + 20 mg synephrine (PWS+S). Initial venous blood serum collections followed 10-12 hours of fasting, with a second and third collection 30-min and 90-min following a pre-workout supplement ingestion. Participants repeated the experiment after a one-week washout period with the alternate supplements in a randomized and counterbalanced manner. Plasma was subsequently extracted and stored at -80°C, and then analyzed by calorimetric assay kits to measure serum creatine level. Data presented mean ± SD and mean change ± 95% CI. Data were analyzed by two-way repeated measure ANOVA and one-way repeated measure ANOVA. Result: We observed significant effects for treatment (p<0. 001), time (p<0. 001), and the treatment x time interaction (p<0.001) on serum creatine. Overall, significant differences for creatine were observed for PWS+S (2.62 μmol/L; 95% CI, 2.29, 2.94) and PWS (2.31 μmol/L; 95% CI, 1.97, 2.65) vs. PLA (0.71 μmol/L; 95% CI, 0.63, 0.80). The effect also showed significant differences at 30-min (2.37 μmol/L; 95% CI, 2.02, 2.71) and 90-min (2.57 μmol/L; 95% CI, 2.14, 2.99) from pre-ingestion (0.71 μmol/L; 95% CI, 0.63, 0.78). Treatment x time interaction showed significant increases in serum creatine levels for PWS+S (3.28 μmol/L; 95% CI, 2.80, 3.76) and PWS (3.13 μmol/L; 95% CI, 2.52, 3.74) vs. PLA (0.69 μmol/L; 95% CI, 0.60, 0.78) at 30-min, and PWS+S (3.89 μmol/L; 95% CI, 3.21, 4.57) and PWS (3.10 μmol/L; 95% CI, 2.48, 3.71) vs. PLA (0.71 μmol/L; 95% CI, 0.61, 0.82) at 90-min of supplement ingestion. Although there was no significant difference between PWS+S and PWS (p=0.48) at 30-min post-ingestion, at 90-min post-ingestion, serum creatine was significantly increased (p<0.001) in PWS+S subjects (0.79 μmol/L; 95% CI, 0.37, 1.21) compared to PWS subjects. Area under the curve (AUC) analysis also showed a significant difference between treatments (p<0.001). Post-hoc comparisons demonstrated significant differences between PWS+S (5.57 μmol/L; 95% CI, 4.88, 6.25) and PWS (5.50 μmol/L, 95% CI, 4.26, 5.82) vs. PLA (1.42 μmol/L; 95% CI, 1.25, 1.59) for 2-hrs. PWS+S (0.53 μmol/L; 95% CI, 0.02, 1.04) vs. PWS was also showed significance throughout testing. Conclusion: The acute ingestion of a dietary PWS containing beta alanine, creatine nitrate, arginine AKG, N-acetyl tyrosine, caffeine, and Mucuna pruriens increased serum creatine levels 2-hr post-ingestion compared to PLA and the addition of synephrine enhanced this effect.

      • KCI등재

        일회성 유산소운동 후 다량의 알코올섭취가 HPA축과 체온의 주기리듬에 미치는 영향

        고성경(Ko, Seong-Kyeong),류호상(Yoo, Ho-Sang),권영우(Kwon, Yeung-Woo),김한철(Kim, Han-Chu),권광선(Kwon, Kwang-Sun),김진형(Kim, Jin-Heung) 한국체육과학회 2014 한국체육과학회지 Vol.23 No.1

        The aim of this study was to investigate the effects of an acute large amount of alcohol ingestion(17% distilled alcohol, 9ml/㎏ per 1㎏ body weight) after aerobic exercise on circadian rhythm of HPA axis(ACTH, cortisol), body temperature. Alcohol degradation ability also measured. Twelve male (average age 33.5years, weight 73.1㎏) took part in this study and performed 3 trials (alcohol ingestion after exercise, alcohol ingestion. placebo ingestion) in a randomized, cross-over design at intervals of 1 weeks. They drank dry white wine(mixed with orange) at 18:00hours during 45 minutes. Placebo treatment ingested identical amount of fluid not contained alcohol. Resting blood sample extracted at 24:00hours and 0700hours(following day) for measuring circadian variation. Extra blood also extracted during 30, 120min after alcohol ingestion for alcohol degradation ability. Exercise treatment group performed running at 70%HRmax during 30 minutes by treadmill. Blood cortisol concentration were significantly high by only alcohol ingestion as compared to exercise+alcohol ingestion and placebo ingestion treatment during 07:00 and 24:00hours. The present findings suggest that large alcohol ingestion may deteriorate circadian rhythm and exercise before alcohol ingestion alleviate thus alcohol ingestion related circadian rhythm disorder.

      • 飮酒後 얼굴 붉어지는 사람에 있어서 運動이 直腸 및 皮膚溫度에 미치는 效果

        玄成澤,黃駿河,黃樹寬,朴載植 慶北大學校 醫科大學 1986 慶北醫大誌 Vol.27 No.1

        飮酒後 얼굴 붉어지는 사람에 있어서 運動이 直腸 및 皮膚溫度에 미치는 效果를 究明하기 위하여 建康한 남자 대학생 57명을 對象으로 하여 물 投與 對照群(W), 에타놀 投與後 얼굴 안 붉어지는 群(N)과 붉어지는 群(F), 물 投與後 運動시킨 群(WE), 에타놀 投與後 運動시켜서 얼굴 안 붉어지는 群(NE) 및 에타놀 投與後 運動시켜서 얼굴 붉어지는 群(FE)으로 구분하였다. 에타놀 投與群(N, F, NE, FE)에는 體液量 ℓ當 25% 에타놀 3㎖를 經口投與하였고, 물 投與群(W, WE)에는 에타놀대신 同量의 물을 投與하였다. 運動시킨 群(WE, NE, FE)은 물 또는 에타놀 投與 直後부터 3분간 rebounder上에서 ?直뛰기를 실시하였다. 體溫은 Yellow Springs Instrument製 telethermometer 44 TA 를 사용하여 直腸溫度와 大腿, 이마, 뺨 및 목皮膚溫度를 測定하였다. 直腸溫度는 에타놀 投與後 F群과 N 群은 모두 감소했고, 運動시킨 WE 群은 증가했으며, NE群은 運動後 40, 60 및 120분에 감소했다. FE群은 運動後 10분에 증가했으나 45 및 60분에는 감소했고, 30, 45 및 60분에는 WE群에 비해 낮았다. 大腿皮膚溫度는 에타놀 投與後 N 群은 별 변화가 없으나, F 群은 45분부터 다소 증가했다. NE 群은 運動後 45분부터 다소 증가했다. NE 軍은 運動後 45분부터 증가했고 FE 群은 運動後 계속 증가했다. 이마皮膚溫度는 에타놀 投與後 N 群은 30, 45, 60 및 90분에 증가했고, F 群은 45분에 W 群보다 높았다. 運動後 WE 群과 NE 群은 감소하는데 비해 FE 群은 증가했다. NE 群은 運動後 4분에 N 群에 비해 낮았고 FE 群은 10분에 WE群에 비해 높았다. 뺨皮膚溫度는 F 群에 에타놀 投與後 10분에 증가했고, 10, 20 및 30분에는 W 群보다 높았다. 運動後 WE 群은 20분에 증가했고, NE 群은 4, 90 및 120분에 감소했으며, FE 群은 10분부터 120분까지 증가했다. 목皮膚溫度는 에타놀 投與後 N 群은 4분에 W 群보다 높았고, F 郡은 에타놀 投與後 다소 증가했다. WE 群은 運動後 4분에 감소했고, NE 群은 4 및 90분에 감소했으나 FE 群은 20 및 60분에 증가했다. NE 群은 4분에 N 群에 비해 낮았다. 收縮期血壓은 에타놀 投與後 N 群은 4 및 10분에 증가했고, F 群은 다소 증가했으며, 運動後 WE 群은 4, 10 및 20분에 증가했고, NE 群도 4 및 10분에 증가했다. FE 群은 4분에 증가했고 F 群보다도 높았다. 擴張期血壓은 N 群이 에타놀 投與後 4 및 10분에 有意하게 높았으며, 心博數는 W 群은 물 投與後 20분에 증가했고, 에타놀 投與後 N 群은 별 변화가 없었으나, F群은 증가하여 20분에 최고치를 나타내고 120분까지도 높았으며 10 및 60분은 W 群보다 높았다. 運動後 WE 群, NE 群 및 FE 群 모두 증가했으며, 이로서 NE 群은 4분에 WE 群보다 낮았고 N 群보다는 높았으며, FE 群은 F 群보다 높았다. 이상을 綜合해 볼때 에타놀이 直腸溫度를 감소시키고 皮膚溫度를 증가시키며, 이런 현상이 얼굴 붉은 群에서 더 크게 나타난 것은 에타놀에 의한 血管擴張과 休息中인 顔面 毛細管의 活性等이 얼굴 붉은 群에서 더 顯著함을 의미하고, 運動으로 體溫이 증가한 것은 運動中 代謝가 旺盛하여 熱生産이 증가된 것을 의미한다. 또한 血壓은 運動負荷後 급증하였고, 心博數는 얼굴 붉은 群에서 에타놀 投與 및 運動後에 안 붉은 群에 비해 크게 높은 값을 보였다. The facial flush associated with ethanol ingestion is believed to be more prominent among the oriental people than the caucasian population, and is attributed to the total lack or a considerable decrease of the liver aldehyde dehydrogenase level. However, a little has been reported on the change of the body temperature, including the facial skin temperature, which may lead to some cluses as to the redistribution of blood to the surface areas of the body. In the present study, an effort was directed to elucidate the possible change of the body temperature including the rectal and some surface areas of the body in men showing facial flush following acute ethanol ingestion. Also physical exercise was combined with ethanol ingestion and the change of the body temperature was compared with the non-flushed subjects either with ethanol ingestion or exercise alone. Fifty-five healthy male college students were randomly selected for the study and after 6 or more hours of fasting, either 3 ml of 25% ethanol(Soju) per liter of total body water(Experimental group) or the same dose of water(control group) was administered. Exercise performed was the vertical jumping on a rebounder for 3 min immediately after drinking. The subjects were classified into 6 groups; i, e, water ingestion(W), flushed(F) and non-flushed(N) groups after ethanol ingestion, water ingestion and exercise(WE), flushed(FE) and non-flushed(N) groups after ethanol ingestion, water ingestion and exercise(WE), flushed(FE) and non-flushed(NE) groups after ethanol ingestion and exercise. The telethermometer 44TA by the Yellow Spring Instrument Co. was used for the measurement of temperature, and the rectal, thigh skin, forehead skin, cheek skin and neck skin temperature was measured. The systolic and diastolic peessure as well as heart rate also were recorded. The rectal temperature both in flushed(F) and non-flushed(N) groups were lowered comparing with the water ingested control, and WE group showed elevated rectal temperature while NE group showed lowered values at 40, 60 and 120 min after the exercise. The FE group showed a higher rectal temperature at 10 min but decreased values were obtained at 45 and 60 min after the exercise. The thigh skin temperature in N group showed little change but F, NE and FE groups all showed elevated values comparing with the control. The forehead skin temperature in N group showed elevated values at 30, 45, 60 and 90 min after ethanol ingestion, and F group increased temperature at 45 min comparing with W group. After the exercise, both WE and NE groups showed lowered values while FE group showed increased value. NE group showed decreased value at 4 min after the exercise comparing with N group while FE group at 10 min showed a higher value than WE group. The cheek skin temperature in F group was generally higher than W group throughout the experiment. After the exercise, WE group showed a higher value at 20 min while NE group showed decreased value at 40, 90 and 120 min whereas FE group showed higher values from 10 min through 120 min. The neck skin temperature both in N and F groups showed elevated values after ethanol ingestion comparing with the control. WE and NE groups showed generally lowered neck skin temperature after the exercise while FE group showed elevated values at 20 and 60 min after the exercise. The systolic and diastolic blood pressure were generally elevated in all the groups, and FE group in particular showed higher values at 4 min which was also higher than F group. From the above, it is concluded that ethanol ingestion results in the decrease of the rectal temperature and increase of the skin temperature. The above-mentioned phenomena are more prominent in the flushed group, which suggests that the dilatation of the peripheral blood vessels and the activation on the dormant facial capillaries are more marked in the flushed subejcts. The general elevation of the body temperature after the exercise may be the result of the enhanced general metabolism leading to the increased production of bodily heat.

      • KCI등재

        Characteristics of Plastic Debris Ingested by Sea Turtles: A Comprehensive Review

        문예림,심원준,홍상희 한국해양과학기술원 2023 Ocean science journal Vol.58 No.4

        Sea turtles, an ecologically vital marine species, face the mounting threat of plastic ingestion. To devise effective mitigation strategies, a nuanced understanding of the characteristics of ingested plastics is essential. Previous reviews have predominantly concentrated on the frequency of occurrence (%FO) and quantity of ingested plastics. In this study, we present an update to the literature on %FO and quantity of ingested plastics and also introduce a novel review of the morphology, color, and polymer composition of ingested plastics. This analysis draws upon 110 scholarly articles on plastic ingestion by sea turtles. Additionally, we explore geographical variations in both the quantity and characteristics of ingested plastics. Most of the analyzed studies were conducted in the Americas and Europe. We found that approximately 54% of examined sea turtles had ingested plastic debris. Loggerhead sea turtles ingested more foams than green sea turtles (Wilcoxon rank-sum test, p < 0.05). By contrast, green sea turtles exhibited a higher ingestion on films (Wilcoxon rank-sum test, p > 0.05). Our study also underscored the paucity of data regarding the original usage of ingested plastics. White and transparent plastics were most commonly ingested. Additionally, polymers with a lower density than seawater, such as polyethylene, polypropylene, and their copolymers, were frequently found. We strongly advocate for future studies to furnish more comprehensive data regarding the ingested plastics, including quantities, morphological and chemical properties, and origins. Such detailed information is indispensable for shaping well-informed and effective strategies to combat plastic ingestion in marine life.

      • KCI등재

        굴 Crassostrea gigas 유생의 먹이생물 섭취 크기

        허영백,전창영,조기채,허성범 한국패류학회 2011 The Korean Journal of Malacology Vol.30 No.4

        Digestibility index of 12 phytoplankton species were invested during the larval development sizes. Ingestible size of phytoplankton varied depending on larval sizes: Isochrysis galbana, I. aff. galbana, Pavlova lutheri, Chlorella ellipsoidea, Nannochloris oculata was ingested 94.2-99.7% all larval sizes. Cheatoceros. calcitrans, C. gracilis and C. simplex could ingest over 90.0% after umbo stage (mean shell length 189.3 ± 13.8 μm). Phaeodactylum triconutum, Dunaliella tertiolecta and Tetraselmis tetrathele could not ingested D-shaped larvae (shell length 65.0-100.0 μm) but ingested 97.3-99.7%, 43.3-99.3%, 48.5-99.3% after then larval stages, respectively. But Thalassiosira weissflogii was ingested 1.0-1.7% only at full grown stage. Over 50.0% ingestion cell size was D-shape stage larvae with smaller than mean 102.3 μm in shell length could ingest phytoplankton with 4.6 μm in both major and minor axis and up to 9.3 μm in minor axis basis for larger than mean 158.3 μm in shell length, respectively. At all larval stages, phytoplankton with larger than 10.0 μm in both major and minor axis could not be ingested. 유생의 발달크기에 따라 미세조류 12종에 대하여 섭취 가능성을 조사한 결과 유생의 크기에 따라 섭취 가능한 미세조류는많은 차이를 보였다. 전체 유생크기에서 I. galban, I. aff. galbana, P. lutheri, C. ellipsoidea, N. oculata는94.2-99.7%의 섭취율를 보였고, C. calcitrans, C. gracilis,C. simplex는 평균 각장 189.3 ± 13.8 μm 크기인 중형 각정기 이 후 90.0% 이상의 섭취율을 보였다. P. triconutum,D. tertiolecta, T. tetrathele는 평균 각장 65.0-100.0 μm의D형 유생은 섭취가 관찰되지 않았지만, 이 후 유생에서는 각각 97.3-99.7%, 43.3-99.3%, 48.5-99.3% 섭취하였다. 그러나 T. weissflogii는 평균 각장 306.2 ± 14.7 μm 이상에서1.0-1.7%의 섭취율을 보였지만, 전체 유생기동안 그의 섭취가되지 않았다. 이상의 결과를 이용해 전체 50.0% 이상 섭취 가능한 먹이생물의 세포크기를 조사한 결과, 평균 각장 102.3μm 이하의 D형 단계는 장축과 단축 모두 4.6 μm 이하,158.3 μm 미만에서는 장축기준으로 9.3 μm 미만까지 섭취가 가능하고, 158.3 μm 이상 크기는 단축 기준 9.3 μm까지섭취가 가능한 것으로 나타났다. 전제 유생기 동안 장축과 단축을 포함해서 10.0 μm 이상은 섭취가 되지 않았다.

      • A Pair of Pharyngeal Gustatory Receptor Neurons Regulates Caffeine-Dependent Ingestion in <i>Drosophila</i> Larvae

        Choi, Jaekyun,van Giesen, Lena,Choi, Min Sung,Kang, KyeongJin,Sprecher, Simon G.,Kwon, Jae Young Frontiers Media S.A. 2016 Frontiers in cellular neuroscience Vol.10 No.-

        <P>The sense of taste is an essential chemosensory modality that enables animals to identify appropriate food sources and control feeding behavior. In particular, the recognition of bitter taste prevents animals from feeding on harmful substances. Feeding is a complex behavior comprised of multiple steps, and food quality is continuously assessed. We here examined the role of pharyngeal gustatory organs in ingestion behavior. As a first step, we constructed a gustatory receptor-to-neuron map of the larval pharyngeal sense organs, and examined corresponding gustatory receptor neuron (GRN) projections in the larval brain. Out of 22 candidate bitter compounds, we found 14 bitter compounds that elicit inhibition of ingestion in a dose-dependent manner. We provide evidence that certain pharyngeal GRNs are necessary and sufficient for the ingestion response of larvae to caffeine. Additionally, we show that a specific pair of pharyngeal GRNs, DP1, responds to caffeine by calcium imaging. In this study we show that a specific pair of GRNs in the pharyngeal sense organs coordinates caffeine sensing with regulation of behavioral responses such as ingestion. Our results indicate that in <I>Drosophila</I> larvae, the pharyngeal GRNs have a major role in sensing food palatability to regulate ingestion behavior. The pharyngeal sense organs are prime candidates to influence ingestion due to their position in the pharynx, and they may act as first level sensors of ingested food.</P>

      • KCI등재

        굴, Crassostrea gigas 유생의 먹이생물 섭취 크기

        허영백,전창영,조기채,허성범,Hur, Young-Baek,Jeon, Chang-Young,Cho, Kee-Chae,Hur, Sung-Bum 한국패류학회 2011 The Korean Journal of Malacology Vol.27 No.4

        유생의 발달크기에 따라 미세조류 12종에 대하여 섭취 가능성을 조사한 결과 유생의 크기에 따라 섭취 가능한 미세조류는 많은 차이를 보였다. 전체 유생크기에서 I. galban, I. aff. galbana, P. lutheri, C. ellipsoidea, N. oculata는 94.2-99.7%의 섭취율를 보였고, C. calcitrans, C. gracilis, C. simplex는 평균 각장 $189.3{\pm}13.8{\mu}m$ 크기인 중형 각 정기 이후 90.0% 이상의 섭취율을 보였다. P. triconutum, D. tertiolecta, T. tetrathele는 평균 각장 $65.0-100.0{\mu}m$의 D형 유생은 섭취가 관찰되지 않았지만, 이후 유생에서는 각각 97.3-99.7%, 43.3-99.3%, 48.5-99.3% 섭취하였다. 그러나 T. weissflogii는 평균 각장 $306.2{\pm}14.7{\mu}m$ 이상에서 1.0-1.7%의 섭취율을 보였지만, 전체 유생기동안 그의 섭취가 되지 않았다. 이상의 결과를 이용해 전체 50.0% 이상 섭취 가능한 먹이생물의 세포크기를 조사한 결과, 평균 각장 $102.3{\mu}m$ 이하의 D형 단계는 장축과 단축 모두 $4.6{\mu}m$ 이하, $158.3{\mu}m$ 미만에서는 장축기준으로 $9.3{\mu}m$ 미만까지 섭취가 가능하고, $158.3{\mu}m$ 이상 크기는 단축 기준 $9.3{\mu}m$까지 섭취가 가능한 것으로 나타났다. 전제 유생기 동안 장축과 단축을 포함해서 $10.0{\mu}m$ 이상은 섭취가 되지 않았다. Digestibility index of 12 phytoplankton species were invested during the larval development sizes. Ingestible size of phytoplankton varied depending on larval sizes: Isochrysis galbana, I. aff. galbana, Pavlova lutheri, Chlorella ellipsoidea, Nannochloris oculata was ingested 94.2-99.7% all larval sizes. Cheatoceros calcitrans, C. gracilis and C. simplex could ingest over 90.0% after umbo stage (mean shell length $189.3{\pm}13.8{\mu}m$). Phaeodactylum triconutum, Dunaliella tertiolecta and Tetraselmis tetrathele could not ingested D-shaped larvae (shell length $65.0-100.0{\mu}m$) but ingested 97.3-99.7%, 43.3-99.3%, 48.5-99.3% after then larval stages, respectively. But Thalassiosira weissflogii was ingested 1.0-1.7% only at full grown stage. Over 50.0% ingestion cell size was D-shape stage larvae with smaller than mean $102.3{\mu}m$ in shell length could ingest phytoplankton with $4.6{\mu}m$ in both major and minor axis and up to $9.3{\mu}m$ in minor axis basis for larger than mean $158.3{\mu}m$ in shell length, respectively. At all larval stages, phytoplankton with larger than $10.0{\mu}m$ in both major and minor axis could not be ingested.

      • KCI등재

        운동 후 다량의 알코올 섭취가 회복 후 ET-1, 순환기능, 젖산에 미치는 영향

        고성경(Koo, Seong-Kyeong),권영우(Kwon, Yeung-Woo) 한국체육과학회 2014 한국체육과학회지 Vol.23 No.2

        The aim of this study was to investigate the effects of acute large alcohol ingestion(17% distilled alcohol, 8ml/㎏ per 1㎏ body weight) on vascular function(ET-1), cardiovascular function(heart rate, blood pressure) and lactate. Twelve recreationally trained middle aged male took part in this study and performed treadmill running(during 30 minutes) with alcohol ingestion, placebo ingestion and alcohol ingestion after acute exercise(75% hear rate reserve). Each subject performed 3 trials in a randomized, cross-over design at intervals of 1 weeks. All parameters were measured next day morning(12 hours after alcohol consumption). Systolic blood pressure and lactate were significantly high by alcohol ingestion as compared to placebo ingestion. Acute exercise before alcohol ingestion alleviated alcohol induced systolic blood pressure increase. The present findings suggest that large alcohol ingestion may deteriorate cardiovascular function although the blood alcohol concentration was completely removed and acute exercise was beneficial for such alcohol ingestion induced blood pressure increase.

      • KCI등재

        알코올 섭취 후 일시적인 굴절변화와 눈 광학성분의 변화

        김정욱(Jung-Ouk Kim),문병연(Byeong-Yeon Moon),유동식(Dong-Sik Yu),김상엽(Sang-Yeob Kim),이상희(SangHee Lee),조현국(Hyun Gug Cho) 한국안광학회 2018 한국안광학회지 Vol.23 No.2

        Purpose: To study the relationship between temporary refractive errors and changes in optical components in eyes after alcohol ingestion. Methods: Sixteen men of 23.8±2.2 years ingested the alcohol (0.70 g/kg body weight). Refractive errors, corneal thickness, corneal eccentricity, corneal curvature, pupil size, intraocular pressure, and length of ocular axis were measured at 1 h, 4 h, and 24 h after alcohol ingestion, and all values were compared with those of before ingestion. Results: At 1 h after alcohol ingestion, refractive errors showed more myopic (p<0.001), corneal curvature increased, and both pupil size and intraocular pressure decreased significantly (p<0.05, p<0.01). Length of ocular axis was longer than before alcohol ingestion. Conclusions: Alcohol ingestion can temporarily induce the more myopic errors through changes of corneal curvature and length of ocular axis compared with non-alcoholic condition.

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