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        The Current Status of SPECT or SPECT/CT in South Korea

        유익동,최은경,정용안 대한핵의학회 2017 핵의학 분자영상 Vol.51 No.2

        The first step to nuclear medicine in Korea startedwith introduction of the gamma camera in 1969. Althoughplanar images with the gamma camera give important functionalinformation, they have the limitations that result from 2-dimensional images. Single-photon emission computed tomography(SPECT) due to its 3-dimensional image acquisition issuperior to earlier planar gamma imaging in image resolutionand diagnostic accuracy. As demand for a hybrid functional andanatomical imaging device has increased, integrated SPECT/CT systems have been used. In Korea, SPECT/CT was for thefirst time installed in 2003. SPECT/CT can eliminate manypossible pitfalls on SPECT-alone images, making better attenuationcorrection and thereby improving image quality. Therefore, SPECT/CT is clinically preferred in many hospitalsin various aspects.More recently, additional SPECT/CT imagestaken from the region with equivocal uptake on planar imageshave been helpful in making precise interpretation as part oftheir clinical workup in postoperative thyroid cancer patients. SPECT and SPECT/CT have various advantages, but its clinicalapplication has gradually decreased in recent few years. While some researchers investigated the myocardial blood flowwith cardiac PET using F-18 FDG or N-13 ammonia, myocardialperfusion SPECT is, at present, the radionuclide imagingstudy of choice for the risk stratification and guiding therapy inthe coronary artery disease patients in Korea. New diagnosticradiopharmaceuticals for AD have received increasingattention; nevertheless, brain SPECT will remain the most reliablemodality evaluating cerebral perfusion.

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        KSNM60 in Clinical Nuclear Oncology

        문승환,조영석,최준영 대한핵의학회 2021 핵의학 분자영상 Vol.55 No.5

        Since the foundation of the Korean Society of Nuclear Medicine in 1961, clinical nuclear oncology has been a major part of clinical nuclear medicine in Korea. There are several important events for the development of clinical nuclear oncology in Korea. First, a scintillating type gamma camera was adopted in 1969, which enabled to perform modern oncological gamma imaging. Second, Tc-99 m generator was imported to Korea since 1979, which promoted the wide clinical use of gamma camera imaging by using various kinds of Tc-99 m labeled radiopharmaceuticals. Third, a gamma camera with single photon emission tomography (SPECT) capability was first installed in 1980, which has been used for various kinds of tumor SPECT imaging. Fourth, in 1994, clinical positron emission tomography (PET) scanner and cyclotron with a production of F-18 fluorodeoxyglucose were first installed in Korea. Fifth, Korean Board of Nuclear Medicine was established in 1995, which contributed in the education and manpower training of dedicated nuclear medicine physicians in Korea. Finally, an integrated PET/CT scanner was first installed in 2002. Since that, PET/CT imaging has been a major imaging tool in clinical nuclear oncology in Korea. In this review, a brief history of clinical nuclear oncology in Korea is described.

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        핵 의학 영상 획득에 대한 이해와 발전: 과거, 현재, 미래에 대한 고찰

        한용수,박상원,서선열,박철수,한만석 한국자기학회 2021 韓國磁氣學會誌 Vol.31 No.1

        Using radioactive isotopes and non-sealed labeling compounds, the brain’s mechanism of action could be analyzed from a molecular perspective using the characteristics of a positron emission tomography (PET) image, which could identify molecular changes in the region of interest in the human body in three dimensions. Similarly, magnetic resonance imaging (MRI) images provide highresolution anatomical information to determine the activity of nerve cells that reflect the activity of brain neurotransmitters and receptors. After measuring the brain neurotransmitter through MRI images and the amount of Blood Oxygenation Level Dependent (BOLD) produced by receptors, certain areas of the brain could identify activation changes. The development of positron emission tomography-magnetic resonance imaging (PET-MRI) has been made to reflect the respective characteristics of PET and MRI images at the same time.

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