Aquilaria 속 식물 분포도에 근거한 沈香(침향)의 학명

김인락 ( In Rak Kim ) 대한본초학회 2013 大韓本草學會誌 Vol.28 No.5

Objectives : The purpose of this study is correct the scientific name of Aquilariae Lignum in Korean Herbal Pharmacoepia. Methods : The production areas of Aquilariae Lignum and its trading status with China in Chinese history, Sanscrit-Chinese Translation Sutra, Naming year and the discovered district in main Aquilaria spp., Several nation`s Pharmacoepia, The Plant List(TPL), Convention on International Trade in Endangered Species of Wild fauna and flora(CITES) and The International Union for Conservation of Nature(IUCN) were cross-checked. Results : The records in the Jiaozhouyiwuzhi written in the early 2nd century said that Aquilariae Lignum was produced in Vietnam. NanfangCaomuZhuang written in 304 said that Agarwood in Vietnam had white flowers. Vietnam had led production and trading of Aquilariae Lignum until Qing Dynasty. Aquilariae Lignum from Malaysia and Indonesia was not traded with China. In Sanscrit-Chinese Translation Sutra, India Aquilariae Lignum was translated as Vietnam Aquilariae Lignum. Aquilaria malaccensis was discovered from Malay-Peninsular in 1783, and has green or dirty yellow flowers. A. agallocha from North-Eastern India in 1814, white flowers. A. crasssna from Vietnam in 1914, white flowers. A. crassna is different from A. malaccensis in several ways, such as flower, fruit, seed and disribution. In several Nation`s Pharmacoepia, A. crassna was a synonym of A. agallocha. But in TPL, CITES and IUCN, A. malaccensis was an accepted name, and A. agallocha was a synonym of A. malaccensis. Conclusions : These results show that the original species of Aquilariae Lignum in Korea Herbal Pharmacoepia should be reversed from A. agallocha to A. crassna Pierre ex Lacomte.

인도네시아에서 수입된 Aquilaria malaccensis 의 감별 연구

김인락 ( In Rak Kim ),박병수 ( Beyung Su Park ) 대한본초학회 2011 大韓本草學會誌 Vol.26 No.1

Objectives: The purpose of this research is to identify the actual origin species imported as Aquilaria malaccensis from Indonesia. Methods: After producing the permanent preparat by cutting off the specimen thinly, we observed its characteristics. Results: The imported ones have not interxylary parenchyma, so none is in the genus aquilaria. Since the aliform parenchyma is mostly observed around the vessel pore, they are in the genus gonystylus, and the rest have no aliform parenchyma, so their specimen is unidentified. Conclusion: The imported as A. malaccensis are not in the genus aquilaria, but most of them are in the genus gonystylus and, for the rest, the specimen is unidentified.

침향(沈香)의 산지와 무역에 근거한 기원 연구

김광민 ( Kwang Min Kim ),김인락 ( In Rak Kim ) 대한본초학회 2011 大韓本草學會誌 Vol.26 No.4

Objective: The purpose of this study is to determine the origin of Aquilariae Lignum. Method: Firstly identify the production areas of Aquilariae Lignum and its trading status with China in Chinese history through Chinese historical books such as Twenty-Five Histories(二十五史) and the records of the Chosun Dynasty and then, compare the distribution of the genus Aquilaria in the concerned areas. Result: Since the records in the NanfangCaomuZhuang(南方草木狀) written in 304 saying that Aquilariae Lignum was produced in Vietnam and had white flowers, Vietnam had led production and trading of Aquilariae Lignum until Qing Dynasty(淸代). Even though Thailand traded Aquilariae Lignum during Qing Dynasty, however, the volume was at a low level. Aquilariae Lignum from southern Thailand, Malaysia and Indonesia was rated as low quality and low-priced because of its fishy smell and strong flavor. Conclusion: These results show that the origin of Aquilariae Lignum comes from Vietnam and this species is distinguished from the ones of Indodesia or Malaysia.

자외선A로 손상된 DNA의 회복과 DNCB에 의한 알러지성 접촉피부염에 대한 표고버섯과 침향 추출 혼합물의 효과

김민섭,황현익,이유리,김호원,박종군,Kim, Min Seob,Hwang, Hyun Ik,Lee, Yu Ri,Kim, Ho Won,Park, Jong Kun 한국식품영양학회 2015 韓國食品營養學會誌 Vol.28 No.5

The effects of extracts from Lentinula edodes (L. edodes) and Aquilariae agallocha (A. agallocha) on the DNA damage response in ultraviolet A (UVA)-exposed HaCaT cells and on the allergic contact dermatitis caused by 2,4-dinitro-chlorobezene (DNCB) were investigated. When UVA-exposed cells were incubated for 24 hours in medium containing L. edodes or A. agallocha extract, the level of 8-OHdG and CPD decreased in a concentration-dependent manner. The combined treatment with both extracts potentiated the decrease in UVA-induced 8-OHdG and CPD levels as compared with those following treatment with a single extract. In addition, the two extracts showed preventive effects against the UVA-induced reduction in collagen levels. Furthermore, the blood levels of IgE, IL-6, and histamine decreased more significantly upon combined treatment with L. edodes and A. agallocha extracts as compared with those following treatment with single extracts in DNCB-induced allergic contact dermatitis in the ICR mouse. The results of the present study suggest that the components with in the extracts of L. edodes and A. agallocha can help to prevent of UVA-induced genomic instability via a decrease in DNA damage, and to decrease the DNCB-induced allergic dermatitis via modulation of relevant proteins including IgE and IL-6. Further study is needed to clarify the purified components related to the preventative effects of the two extracts against UVA- or DNCB-induced genomic damage.

침향 추출물의 라디칼 및 췌장 지방분해 효소저해 활성 평가

이하영,이인철,곽재훈,김태훈 한국식품저장유통학회 2015 한국식품저장유통학회지 Vol.22 No.3

In a continuing screening of selected medicinal plants native to South Korea, the antioxidant and pancreatic lipase inhibitory activities of an aqueous methanolic extract from the heartwood of Aquilaria agallocha were investigated. Eighty percent of the methanolic extract of A. agallocha was further divided into CH2Cl2, EtOAc and n-BuOH in order to yield four solvent-soluble portions, namely CH2Cl2-soluble, EtOAc-soluble, n-BuOH-soluble and H2O residue. The antioxidant properties were evaluated by employing radical scavenging assays using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS+) radicals, while the anti-obesity efficacy of A. agallocha extracts and solvent-soluble portions were tested by porcine pancreatic lipase assay. All tested samples showed dose-dependent radical scavenging and pancreatic lipase inhibitory activities. Among the tested extracts and solvent-soluble portions, the CH2Cl2-soluble portion showed much higher radical scavenging activity and pancreatic lipase inhibitory properties when compared with other solvent-soluble portions. This result suggested that there was a significant relationship between the total phenolic content and biological efficacies, and A. agallocha extract might be considered as a new potential source of natural antioxidants and as a pancreatic lipase inhibitory source. A more systematic investigation of this biomass will be performed for further investigation of activity against antioxidative and anti-obesity effects.

침향(沈香)의 목부조직(木部組織)

김인락 ( In Rak Kim ),박상진 ( Sang Jin Park ) 대한본초학회 2005 大韓本草學會誌 Vol.20 No.3

GC-MS를 이용한 침향류의 성분 비교 연구

신광호 ( Kwhang Ho Shin ),최규열 ( Kyu Yeol Choi ),조성용 ( Sung Yong Cho ),안덕균 ( Duk Kyun Ahn ),박성규 ( Seong Kyu Park ) 대한본초학회 2011 大韓本草學會誌 Vol.26 No.1

Objectives: The purpose of this study is to evaluate the quality of four different kinds of agarwood and analysis chemical constituents by GC-MS. Methods: Four source plants were two of Vietnamese agarwood, Indonesian agarwood and Myanmar agarwood. These plant materials were named sample No. 1-4. The chemical constituents of each agarwood were analysed by GC-MS. Results: GC-MS analysis showed that β-selinene was found in all the samples. The Vietnamese agarwood, Sample 1, and 4 has contained 6.861% and 7.497% of β-selinene and reached the highest level at the retention times 46.245 and 46.274 (min). Sample 2, the Myanmar agarwood has contained 1.608%, the lowest level of β-selinene, and it also has contained about 20% of α-,β-,γ-eudesmol and 4.076% of valerianol. Sample 3, the Indonesian agarwood has contained 9.59% of α-selinene, 9.493% of β-selinene and shown its highest level (more than 19%) at the retention time 43.998 (min). Conclusion: It suggested that β-selinene could be a standard marker to evaluate agarwood by GC-MS analysis.

침향의 품질평가에 관한 연구

장승엽,강신정,성락선,최돈웅,이종필,신지현,정영자,김종환,김영호,원도희 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

대한약전외 한약(생약)규격집에 수재된 침향의 수입이 증가함에 따라 진위여부에 대한 문제가 대두되었으나, .t. ogaffocfD의 기원식물에 대한 자료가 미비하여, 구입한 인도네시아, 중국 및 베트남산 검체의 구성성분비교를 수행하였다. 이들 검체는 전통한방서에 의한 관능겋사에서는 동일한 결과를 나타내었다. 그러나 인도네시아산 검체와 중국산 검체는 그 구성성분이 유사하였으나, 베트남산 겅체는 상당히 다른 구성을 보였다. TLC 분석에서 인도네시아산 검체와 중국산 검체는 많은 형광반점을 나타내었으나, 베트남산 검체는 형꽁반점보다는 10%-산시액 발색후에 나타나는 반점이 많았다. 또한 정유 구성성분도 베트남산 검체는 인도01시아산 겋체와 비교할 때 구성성분이 상이하였다. The authenticity and actual species of .Afuifario ognffocAD listed in Korea Herb Pharmacopoeia on market according to increasing rate of import is discussed. However, thereare few report and research about 4. ogoffocfo and another species. In this study, the chendcalcomponents of agarwood collected from Indonesia, Chha and Vietnam are compared by TLC,HPLC and GC analysis. ÷Tdelltification of agarwood to the species level is beyond the ability bythe method of traditional book of medicines. Agarwoods of Indonesia and China have sunilarpattern of their chemical component, but qdte differ from its of Vietnam. In TLC analysisresult, there are so many spots under fluorescence light in the agarwood of Indonesia andChina. However spots can be detected by coloring with 10%-H2s04 in Vietnamese agarwood.