트리플 헬릭스 모형(Triple-Helix Model)을 활용한 주민자치회 이해관계자 집단 간 상호작용 및 성과요인 연구: 사회적 자본의 매개효과를 중심으로

김흥주,강인호,황광선 (재) 한국지방행정연구원 2024 地方行政硏究 Vol.38 No.1

본 연구는 첫째, 읍면동 단위에 설치되어 있는 주민자치회를 중심으로 주민자치의 중요행위자 간의 상호작용을 분석해 실제 이들 간의 어떠한 모습을 보여주고 있는지 살펴보고 주민자치회의 성과요인을 실증적으로 살펴보기 위함이다. 둘째, 사회적 자본이 주민자치회 주요행위자와 주민자치성과 간의 관계를 매개하는 지를 실증적으로 검정하고자 하는데 있다. 트리플 헬릭스 모형(Triple Helix Model) 이론적 모형을 토대로 구조방정식을 활용한 세종시 주민자치회 사례 분석을 하였다. 분석결과 (1) 주민자치회와 읍면동행정 관계(helix1)와 (2) 주민자치회와 의회관계(helix2)는 주민자치 성과에 양의 영향을 주는 것으로 나온다. helix1, helix2와 주민자치 성과의 관계에서 사회적 자본인 효능감과 주민참여는 부분 매개효과를 갖는 것으로 확인된다. 이를 통해 주민자치회 이해관계자의 협력적 상호작용은 사회적 자본을 증대시키며 주민자치회가 활성화될 수 있는 가능성을 열어준다는 점을 생각해 볼 수 있다. 결국, 주민자치회, 읍면동 행정, 지역사회 단체, 그리고 지방의회간의 상호 협력적인 상호작용이 중요하다는 시사점과 함께 정책적 제언을 제시하였다. This study aims to investigate the dynamics among key players in promoting resident self-governance councils, with a focus on resident self-governance councils at the town, township, and dong (neighborhood) levels. The objective is to assess the current state of interactions between these councils and empirically analyze the factors influencing their performance. Additionally, the study seeks to test whether social capital plays a mediating role in the relationship between key actors in residents' self-governance associations and the performance of residents' autonomy. Drawing on the theoretical framework of the Triple Helix Model, the Sejong City Residents' Association serves as a case study, employing structural equations for analysis. The findings indicate that (1) the relationship between residents' self-governing associations and town/village administration (helix1) and (2) the relationship between residents' autonomous associations and the council (helix2) positively impact the performance of resident self-governance councils. Moreover, the study reveals that social capital, efficacy, and resident participation partially mediate the relationship between helix1, helix2, and resident autonomy performance. This suggests that collaborative interactions among stakeholders in neighborhood associations enhance social capital, potentially revitalizing these associations. In the end, he suggested the importance of mutually cooperative interaction between residents' autonomy, Eupmyeon-dong administrations, community groups, and local councils.

Implementation and application of helix–helix distance and crossing angle restraint potentials

Lee, Jinhyuk,Im, Wonpil Wiley Subscription Services, Inc., A Wiley Company 2007 Journal of computational chemistry Vol. No.

<P>Based on the definition of helix–helix distance and crossing angle introduced by Chothia et al. (J Mol Biol 1981, 145, 215), we have developed the restraint potentials by which the distance and crossing angle of two selected helices can be maintained around target values during molecular dynamics simulations. A series of assessments show that calculated restraint forces are numerically accurate. Since the restraint forces are only exerted on atoms which define the helical principal axes, each helix can rotate along its helical axis, depending on the helix–helix intermolecular interactions. Such a restraint potential enables us to characterize the helix–helix interactions at atomic details by sampling their conformational space around specific distance and crossing angle with (restraint) force-dependent fluctuations. Its efficacy is illustrated by calculating the potential of mean force as a function of helix–helix distance between two transmembrane helical peptides in an implicit membrane model. © 2006 Wiley Periodicals, Inc. J Comput Chem 28: 669–680, 2007</P> <B>Graphic Abstract</B> <P> <img src='wiley_img/01928651-2007-28-3-JCC20614-gra001.gif' alt='wiley_img/01928651-2007-28-3-JCC20614-gra001'> </P>

두꺼운 트리플 헬릭스: 연구중심대학과 지역혁신체제의 역동적 전환

김종영 한국사회역사학회 2023 담론 201 Vol.26 No.3

지역혁신체제는 과학기술사회학과 대학사회학에서 30여 년간 논의된 중요한 주제다. 지역혁신체제에서 가장 중요한 행위자는 대학, 기업, 정부다. 이 세 행위자를 통합하여 지역혁신체제를 설명하는 방식을 트리플 헬릭스(Triple Helix) 또는 산학관 연계라고 부른다. 이 논문은 지역혁신체제의 성공은 얇은 트리플 헬릭스(Thin Triple Helix)와 대비되는 두꺼운 트리플 헬릭스(Thick Triple Helix)에 있음을 강조한다. 이 논문은 특히 지역혁신체제의 전범으로 평가받는 대표적인 미국의 연구중심대학과 지역혁신체제를 중심으로 트리플 헬릭스의 ‘역동적 전환’(dynamic turn)을 설명하고 두꺼운 트리플 헬릭스의 형성이 지역혁신체제 성공의 핵심이라고 설명한다. 따라서 이 논문은 역사적 사례연구를 중심적인 접근법으로 택한다. 결론적으로 이 논문은 지역혁신체제의 성공은 연구중심대학, 기업, 정부의 누적적이고 창의적인 상호작용에 의한 ‘두꺼운 트리플 헬릭스’의 형성에 달려 있다고 강조한다. The regional innovation system is an important topic that has been discussed in the sociology of science and technology and the sociology of university for over 30 years. The most important actors in the regional innovation system are universities, corporations, and governments. The method of integrating these three actors to explain the regional innovation system is called the Triple Helix or industryacademia- government linkage. This paper emphasizes that the success of the regional innovation system lies in the thick triple helix as opposed to the thin triple helix. In particular, this paper explains the ‘dynamic turn’ of the triple helix, focusing on representative research universities and regional innovation systems in the United States, which are evaluated as models of regional innovation systems, and the formation of a thick triple helix is the key to the success of regional innovation systems. Therefore, this paper adopts historical case studies as its central approach. In conclusion, this paper emphasizes that a successful regional innovation system depends on the formation of a ‘thick triple helix’ by the cumulative and creative interaction of research universities, corporations, and government.

Coordinative Helix-Helix Association of Heteroleptic Metallosupramolecular Helicates

유효종 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.1

We report the fabrication of a unique racemic macrocycle via the association of metallosupramolecular helicates. A nickel ({Ni₄}) cluster-based supramolecular helicate, [Ni₈(PDA)₆(CDBA)₃(DMF)₂(H₂O)₄] (1) (PDA = 2,6-pyridinedicarboxylate, CDBA = 4,4’-carbonyldibenzoate, DMF = dimethylformamide) is successfully synthesized and fully characterized. Dimerization of the right (P-) and left (M-) handed helicates of 1 via the coordination of metalloligands, [Ni(PDA₂)]^2- affords {[Ni₈(PDA)₆(CDBA)₃(DMF)_4-Ni(PDA)₂]₂} (2), which can be the representative model of the coordinative helix-helix association of heteroleptic helicates. The solid-state structures of 1 and 2 show excellent and selective CO₂ uptake properties.

RAPD Marker를 이용한 Hedera속 식물의 다양성 조사

정미순,정연화,이자현,최정근,김광수,한태호 한국화훼산업육성협회 2008 화훼연구 Vol.16 No.1

Hedera helix 11계통, Hedera rhombea 3계통, Fatshedera lizei 1계통, 그리고 Fatsia japonica 1계 통을 수집하였다. RAPD primer 10개를 이용하여 수 집된 3속의 재료들의 유전적 다양성을 측정하였다. 3 속을 재료로 사용하여 밴드간 96.9%의 높은 다형성을 보였다. 총 97개의 RAPD 밴드를 이진화하여 UPGMA 방법을 이용하여 계통도를 작성하였다. Hedera helix 계통들은 모두 1개의 그룹에 속하였으며 8계통의 유전 적 거리는 극도로 적었으며 나머지 3계통 역시 유전적 으로 가까웠다. 하지만 형태적으로는 높은 다형성을 보 였다. 따라서 수집된 유전자원을 이용한 돌연변이체 개 발이 가능성이 있는 방법으로 제시되었다. Fatsia japonica는 유전적으로 관계성이 적어 다른 종들과 평 균 0.63의 유전적 거리를 보였다. Hedera helix와 Fatsia japonica 속간 교배를 통하여 개발된 Fatshedera lizei는 Hedera rhombea 계통들과 함께 계통도에서 위치하였다. Eleven accessions of Hedera helix, three accessions of Hedera rhombea, one accession of Fatshedera lizei, and one accession of Fatsia japonica were collected and their genetic diversity was measured by using 10 RAPD primers. Approximately ninety seven percentage of polymorphism was detected, because broad germplasm, three genus, was used. Total 97 bands were scored and a dendrogram was constructed by using an UPGMA method. Accessions belonging to Hedera helix tightly clustered in one group; eight accessions showed extremely narrow genetic differences and the other three accessions also showed significant similarity. Despite of their genetic similarity, they showed morphological variations. The morphological variation with a narrow genetic differences indicated that the ivy cultivars have been indeed developed from a mutation breeding program. Genetically most unrelated Fatsia japonica showed a genetic distance of 0.63 on the average between other species. An accession from Fatshedera lizei developed by crossing between two genus, Hedera helix and Fatsia japonica, was allocated together with accessions from Hedera rhombea.

Analysis of Basic Helix-Loop-Helix Gene Related to Virus Resistance in Squash

( Hyun-min Lee ),( Dae-kook Kim ),( Sang-ki Suh ),( Young-doo Park ) 한국육종학회 2020 Plant Breeding and Biotechnology Vol.8 No.2

Viral diseases in squash are damaging during the early stages of development and cause loss of crop yield and economic value. To reduce the damage caused by viral diseases, resistant cultivars should be bred. The objective of this study was to determine whether there was a relationship between virus resistance and a basic helix-loop-helix (bHLH) gene in squash (Cucurbita pepo L.). To do this, the bHLH transcription factor, known to be related to virus resistance, was isolated and analyzed using C. pepo individuals that were resistant or susceptible to zucchini yellow mosaic virus (ZYMV) and watermelon mosaic virus (WMV). The results showed that a three bp (GAC) deletion in the nucleotide sequences were found in the regulatory region of the CpbHLH gene in susceptible lines. It was confirmed that the deletion region was located near the binding site of the MYB transcription factor associated with the bHLH gene. It could be hypothesized that the susceptibility of susceptible lines may have been due to the lack of important sequences near the transcription factor binding region due to the deletion in the regulatory region, thus suppressing the expression of the gene. Quantitative real-time PCR (qRT-PCR) revealed that the expression level of the bHLH gene in resistant lines was 2.17 times higher than in susceptible lines.

Synthesis of Chiral Bisacylphosphine Oxides and Their Application as Initiators in Helix-Sense-Selective Photopolymerization

Jia-An Zhang,Nian-Fa Yang,Li-Wen Yang,Shi Wu,Ye-Hui Chen,Jin Zhang 한국고분자학회 2013 Macromolecular Research Vol.21 No.6

Three new chiral bisacylphosphine oxides, (-)-bis(menthylformyl)phenylphosphine oxide (1a), (+)-bis(2,4,6-trimethylbenzoyl)menthylphosphine oxide (2a), and (-)-bis(menthylformyl)menthylphosphine oxide (3a),were synthesized using menthol as a chiral source. The synthesized new chiral bisacylphosphine oxides were used as photoinitiators for the polymerization of 1-phenyldibenzosuberyl methacrylate (PDBSMA). The polymerization initiated by chiral bisacylphosphine oxides under UV light irradiation is helix-sense-selective. Among the three prepared chiral bisacylphosphine oxides, the helix-sense-selectivity of bis(menthylformyl)menthylphosphine oxide is highest. The highest specific rotation of poly(1-phenyldibenzosuberyl methacrylate) at 365 nm is +416. The feed molar ratio of monomer to chiral bisacylphosphine oxide and the polymerization temperature have an influence on the helix-sense-selectivity. The lower the feed molar ratio of monomer to chiral bisacylphosphine oxide, the better the helix-sense-selectivity is. The increase of polymerization temperature is propitious to increase the helix-senseselectivity of the photopolymerization.

The effect of the triple helix system and habitat on regional entrepreneurship: Empirical evidence from the U.S.

Kim, Y.,Kim, W.,Yang, T. Elsevier Science Publishers B.V. (North-Holland) 2012 RESEARCH POLICY Vol.41 No.1

The 'triple helix' of the university-industry-government relationship and habitat are accepted as important determinants of innovation and entrepreneurship. However, empirical explorations of the effects of these variables and their interrelationships on regional entrepreneurial activities are highly limited. To fill this gap, we investigate the effect of the triple helix system and habitat on birth and death rates of U.S. firms at the state level. As expected, we find that industrial R&D expenditure plays an important role in promoting regional firm birth. However, university and government R&D also generate a synergistic effect that indirectly influences regional firm birth rates. In addition, we find that the synergy between university and industrial R&D enhances the sustainability of firms, while the interactions between (1) university and government R&D and (2) government and industrial R&D are associated with an increase in firm death. Other factors linked to more favorable conditions for firm formation include higher educational attainment in a region, lower tax rate, and habitat factors affecting quality of life, such as lower housing prices and higher rates of health insurance coverage. In regions with high entrepreneurial activity, we find positive synergistic effects of the interactions between (1) university and government R&D and (2) university and industrial R&D on firm birth rate, suggesting that university R&D plays an important role as an 'entrepreneurial mediator' among the three spheres in the triple helix system. In low entrepreneurial regions, the only triple helix system factors significantly influencing firm birth rate were tax rate. This finding suggests that the independent and interdependent components of the triple helix system and habitat are less powerful in low entrepreneurial regions.

ERROR ANALYSIS FOR APPROXIMATION OF HELIX BY BI-CONIC AND BI-QUADRATIC BEZIER CURVES

Ahn, Young-Joon,Kim, Philsu Korean Mathematical Society 2005 대한수학회논문집 Vol.20 No.4

In this paper we approximate a cylindrical helix by bi-conic and bi-quadratic Bezier curves. Each approximation method is $G^1$ end-points interpolation of the helix. We present a sharp upper bound of the Hausdorff distance between the helix and each approximation curve. We also show that the error bound has the approximation order three and monotone increases as the length of the helix increases. As an illustration we give some numerical examples.

Identification and Characterization of a Putative Basic Helix-Loop-Helix (bHLH) Transcription Factor Interacting with Calcineurin in C. elegans

Soo-Ung Lee,송현옥,Wonhae Lee,Gunasekaran Singaravelu,Jae-Ran Yu,박우윤 한국분자세포생물학회 2009 Molecules and cells Vol.28 No.5

Calcineurin is a Ca2+/Calmodulin activated Ser/Thr phos-phatase that is well conserved from yeast to human. It is composed of catalytic subunit A (CnA) and regulatory subunit B (CnB). C. elegans homolog of CnA and CnB has been annotated to tax-6 and cnb-1, respectively and in vivo function of both genes has been intensively studied. In C. elegans, calcineurin play roles in various signaling path-ways such as fertility, movement, body size regulation and serotonin-mediated egg laying. In order to understand additional signaling pathway(s) in which calcineurin func-tions, we screened for binding proteins of TAX-6 and found a novel binding protein, HLH-11. The HLH-11, a member of basic helix-loop-helix (bHLH) proteins, is a pu-tative counterpart of human AP4 transcription factor. Pre-viously bHLH transcription factors have been implicated to regulate many developmental processes such as cell pro-liferation and differentiation, sex determination and myo-genesis. However, the in vivo function of hlh-11 is largely unknown. Here, we show that hlh-11 is expressed in phar-ynx, intestine, nerve cords, anal depressor and vuvla mus-cles where calcineurin is also expressed. Mutant analyses reveal that hlh-11 may have role(s) in regulating body size and reproduction. More interestingly, genetic epistasis suggests that hlh-11 may function to regulate serotonin-mediated egg laying at the downstream of tax-6.