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      • SCIESCOPUSKCI등재

        A STUDY OF CHINESE ANCIENT COMETARY RECORDS

        ZHOU HONG NAN,ZHUANG WEIFENG,WANG Yu The Korean Astronomical Society 1996 Journal of The Korean Astronomical Society Vol.29 No.suppl1

        From 146 B.C. to A.D. 1760, 363 sets of cometary observations have been recorded in Chinese Ancient Records of Celestial Phenomena. The positions of all recorded comets, or their paths, on the sky are compared. Taking into account the perturbations of all nine planets and using the numerical method of N-body problem, the orbits of well-recorded comets are calculated. Identification of a periodic comet is presented.

      • SCIESCOPUSKCI등재

        Bandwidth-Related Optimization in High-Speed Frequency Dividers using SiGe Technology

        Nan, Chao-Zhou,Yu, Xiao-Peng,Lim, Wei-Meng,Hu, Bo-Yu,Lu, Zheng-Hao,Liu, Yang,Yeo, Kiat-Seng The Institute of Electronics and Information Engin 2012 Journal of semiconductor technology and science Vol.12 No.1

        In this paper, the trade-off related to bandwidth of high-speed common-mode logic frequency divider is analyzed in detail. A method to optimize the operating frequency, band-width as well as power consumption is proposed. This method is based on bipolar device characteristics, whereby a negative resistance model can be used to estimate the optimal normalized upper frequency and lower frequency of frequency dividers under different conditions, which is conventionally ignored in literatures. This method provides a simple but efficient procedure in designing high performance frequency dividers for different applications. To verify the proposed method, a static divide-by-2 at millimeter wave ranges is implemented in 180 nm SiGe technology. Measurement results of the divider demonstrate significant improvement in the figure of merit as compared with literatures.

      • KCI등재후보

        건강신념모델 논문에 대한 내용분석: 국내 건강신념모델 관련 연구 분야 현황과 모델 설명력을 중심으로

        ZHOU NAN,김현미 강원대학교 사회통합연구센터 2023 사회통합연구 Vol.4 No.2

        개인의 건강 행위를 설명하는 데 있어 건강신념모델(health belief model; HBM)은 가장 널리 사용되어 왔다. 본 연구는 건강신념모델을 적용한 국내논문을 대상으로 내용분석을 진행함으로써 연구들의 양상, 추세, 그리고 이론 자체의 설명력과 예측력을 살펴보았다. 2011년부터 2020년까지 10년동안 발간된 111편의 KCI 학술지 논문에 대해 코딩 및 분석을 진행한 결과는 다음과 같다: 첫째, 건강신념모델을 이용한 연구 수량은 증가 중인 것으로확인되었다. 둘째, 건강신념모델은 대중의 질병예방행위를 예측하기 위해만들어진 이론 틀로, 질병예방행위, 건강검진행위, 위생습관행위, 건강증진행위, 운동참여행위 등 건강 계열에 진행된 연구가 대다수다. 셋째, 자기효능감은 HBM의 발전과정에서 추가된 개념으로 관련 연구 중 가장 적게 언급되었으나, 다른 요인에 비해 높은 예측력을 갖고 있다. 넷째, 건강신념모델을 사용한 연구에서 제시된 연구모델은 상대적으로 단순한 양상인 것을 시사하였으며, 건강신념요인에 영향을 미치는 변수에 대한 탐색이 부족한 것으로보인다. 본 연구는 건강신념모델 연구 분야의 현황과 추세를 파악했으며, 향후 연구의 방향과 모델의 발전 방향에 대해 참고자료가 될 수 있음에 의미가 있다. Health Belief Model has been widely used to explain individuals’ health behaviors. This study examined the current status and trends of the research field, and the explanatory power of the theory itself by conducting a content analysis on Korean researches to which the health belief model was applied. We coded and analyzed 111 published in Korea Citation Index(KCI) between 2011 and 2020. Analysis results are as below: First, it was confirmed that the number of studies using the health belief model is increasing. Second, the health belief model is a theoretical framework created to predict the public's disease prevention behavior, due to which most of the studies have been conducted in the health field such as disease prevention behavior, health checkup behavior, personal hygiene, health promotion behavior, and exercise behavior ect. Third, although self-efficacy was added to HBM during its developing process and has been mentioned least among related studies, it has a stronger predictive power than other factors. Fourth, the study using the health belief model suggested that the presented research model was generally simple. A lack of exploration of predictors affecting factors of Health Belief Model was mentioned as one of our conclusions. This study looked into the current status and trends in the field of Health Belief Model, and we look forward to our study serving as a reference of future research directions and model development.

      • KCI등재

        Inhibition of BETs prevents heat shock-induced cell death via upregulating HSPs in SV40 large T antigen transfected cells

        Zhou Nan,Zhang Ye,Lei Gongyun,Chen Yifan,Lin Ting,Liu Qin,Zhao Yinshuang,Mao Jiahui,Jiang Yongying,Mao Renfang 한국유전학회 2022 Genes & Genomics Vol.44 No.10

        Background: Heat shock response is a protected mechanism against environmental changes for the organism, which must be tightly regulated. Bromodomain and extra terminal-containing protein family (BETs) regulate numerous gene expression in many physiological and pathological conditions, including viral infection. SV40 is considered as a highly human disease-associated virus. Objective: We aimed to explore whether BETs play a role in heat shock in SV40 large T antigen transfected cells. Methods: SV40LTA was transfected in HeLa cells using the Lipofectamine 8000. BETs inhibitor JQ1 and I-BET-762 was employed to treat transfected cells and HEK-293 T cells. Heat shock treatment was performed to determine the effect of JQ1 and I-BET-762 on these cells. Western blot and quantitative RT-PCR were carried out to assess the expression of HSP70 and other HSPs. Results: We found that inhibition of BETs by JQ1 and I-BET-762 protects cells from heat shock-induced death in HEK293T cells. Both JQ1 and I-BET-762 induce the expression of HSPs and HSF1 in HEK-293 T cells. However, neither JQ1 nor I-BET-762 fail to induce the expression of HSPs in either HeLa or HBL-1 cells. When SV40 large T antigen was transfected into HeLa cells, the induction of HSP70 expressing and the protection of heat shock-induced cell death are reproduced by JQ1 and IBET treatment in these transfected cells. Conclusions: Inhibition of BETs by JQ1 and I-BET-762 prevents heat shock-induced cell death via upregulating HSPs in SV40 large T antigen transfected cells. Our data indicate a novel function of BETs in SV40 large T antigen transformed cells, affecting HSPs and HSF1 as well as its function on heat shock response.

      • KCI등재

        의료난동 사회질서문란죄 예방에 관한 연구

        주몽닙 ( Zhou Meng-Nan ),박상식 ( Park Sang-sik ) 경상대학교 법학연구소 2022 法學硏究 Vol.30 No.1

        With the development of society and science and technology, the level of medical care has also been continuously improved. However, the problems in the relationship between doctors and patients have not been effectively resolved. The behavior of medicine disturbance is still common, and even the professional medical disturbance group that uses medical disturbance as a means of profit has been born. Medical trouble behavior has serious social harm, not only disrupting the normal diagnosis and treatment order of hospitals and other medical institutions, but even endangering the public and private properties of medical institutions and the personal safety of medical staff. If it is not regulated, it will hinder the healthy development of the doctor-patient relationship and medical order. With the introduction of the Criminal Law Amendment (9) in 2015, medical trouble has officially become a regulatory category of the criminal law. This article aims at the punishment of the crime of medicine trouble type of gathering people to disrupt social order, and discuss the preventive countermeasures of the crime, so as to ensure the normal medical order and promote the healthy development of doctor-patient relationship. Starting from the concept of medical disturbance, this article expounds the legal background of medical disturbance into punishment, analyzes the constituent elements of the crime of medical disturbance by gathering crowds to disrupt social order, and summarizes the causes of the crime from many aspects. The imperfection of the medical institution system can easily cause dissatisfaction among patients and their families, and the lack of understanding of the way of safeguarding rights further intensifies this contradiction between doctors and patients. The difficulties and lack of rights protection methods have spawned professional medical troubles and also fueled the arrogance of bad media, which eventually led to fierce doctor-patient conflicts, which evolved into vicious medical troubles incidents. Only by clarifying the reasons and prescribing the right medicine can we fundamentally prevent the crime of medicine trouble gathering people to disrupt social order, and realize the function of criminal law to protect legal interests.

      • Significant Association of Alpha-Methylacyl-CoA Racemase Gene Polymorphisms with Susceptibility to Prostate Cancer: a Meta-Analysis

        Chen, Nan,Wang, Jia-Rong,Huang, Lin,Yang, Yang,Jiang, Ya-Mei,Guo, Xiao-Jiang,He, Ya-Zhou,Zhou, Yan-Hong Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5

        Background: Alpha-methylacyl-CoA racemase(AMACR) is thought to play key roles in diagnosis and prognosis of prostate cancer. However, studies of associations between AMACR gene polymorphisms and prostate cancer risk reported inconsistent results. Therefore, we conducted the present meta-analysis to clarify the link between AMACR gene polymorphisms and prostate cancer risk. Materials and Methods: A literature search was performed in PubMed, Embase, China National Knowledge Infrastructure (CNKI), Wanfang and Weipu databases. Odds ratios (ORs) and 95% confidence intervals (95%CIs) were calculated to assess the strength of any association between AMACR polymorphisms and prostate cancer risk. Subgroup analyses by ethnicity, source of controls, quality control and sample size were also conducted. Results: Five studies covering 3,313 cases and 3,676 controls on five polymorphisms (D175G, M9V, S201L, K277E and Q239H) were included in this meta-analysis. Significant associations were detected between prostate cancer and D175G (dominant model: OR=0.89, 95%CI=0.80-0.99, P=0.04) and M9V (dominant model: OR=0.87, 95%CI=0.78-0.97, P=0.01) polymorphisms as well as that in subgroup analyses. We also observed significant decreased prostate cancer risk in the dominant model (OR=0.90, 95%CI=0.81-0.99, P=0.04) for the S201L polymorphism. However, K277E and Q239H polymorphisms did not appear to be related to prostate cancer risk. Conclusions: The current meta-analysis indicated that D175G and M9V polymorphisms of the AMACR gene are related to prostate cancer. The S201L polymorphism might also be linked with prostate cancer risk to some extent. However, no association was observed between K277E or Q239H polymorphisms and susceptibility to prostate cancer.

      • KCI등재

        Bandwidth-Related Optimization in High-Speed Frequency Dividers using SiGe Technology

        Chao-Zhou Nan,Xiao-Peng Yu,Wei-Meng Lim,Bo-Yu Hu,Zheng-Hao Lu,Yang Liu,Kiat-Seng Yeo 대한전자공학회 2012 Journal of semiconductor technology and science Vol.12 No.1

        In this paper, the trade-off related to bandwidth of high-speed common-mode logic frequency divider is analyzed in detail. A method to optimize the operating frequency, band-width as well as power consumption is proposed. This method is based on bipolar device characteristics, whereby a negative resistance model can be used to estimate the optimal normalized upper frequency and lower frequency of frequency dividers under different conditions, which is conventionally ignored in literatures. This method provides a simple but efficient procedure in designing high performance frequency dividers for different applications. To verify the proposed method, a static divide-by-2 at millimeter wave ranges is implemented in 180 ㎚ SiGe technology. Measurement results of the divider demonstrate significant improvement in the figure of merit as compared with literatures.

      • KCI등재

        패키지디자인의 다의적 그래픽 표현이 소비자의 구매행동에 미치는 영향에 관한 연구

        주남(Nan Zhou),오용균(Yong Kyun Oh) 한국디자인리서치학회 2023 한국디자인리서치 Vol.8 No.2

        빠르게 발전하고 있는 현대 사회에서 패키지디자인은 다른 어느 때보다 단시간 내에 경쟁 기업들과의 사이에서 차별적인 가치로 소비자에게 기억되어야 한다. 다의적 그래픽이 적용된 패키지디자인은 눈으로 보는 것에 대한 다양한 인식을 발생하는 과정에서 흥미로움과 유쾌함 등의 감성적 반응을 보이게 하고 이러한 극적인 감각의 대립은 소비자가 제품을 기억하는 데 도움을 줄 수 있다. 따라서 본 연구는 먼저 관련 이론을 고찰하고 이를 바탕으로 다의적 그래픽의 중첩, 변환, 변형, 집합 네 가지의 표현방식을 중심으로 사례분석을 진행하였다. 마지막으로 SPSS를 활용하여 실증분석을 통해 AIDA 소비자행동모델을 기반으로 다의적 그래픽의 표현방식이 소비자의 구매행동에 미치는 영향을 검증하였다. 연구결과, 소비자에게 가장 주목받는 표현방식과 가장 기억에 남는 표현방식은 ‘변형’, ‘집합’, ‘중첩’, '변환'의 순으로 나타났으며 '집합' 표현방식이 소비자의 구매행동에 가장 큰 영향을 미치는 것으로 나타났다. 이를 통해 향후 패키지디자인에 관한 연구에 참고할 수 있는 이론 기초와 참고자료를 제공하는 데 의의를 두고 있다. In a rapidly developing modern society, package design should be remembered by consumers as a discriminatory value between competitors in a shorter time than ever before. Package designs with ambiguous figure show emotional reactions such as interest in the process of generating various perceptions of seeing with the eyes, this dramatic confrontation of senses can help consumers remember the product. Therefore, this study first reviewed related theories and conducted case analysis focusing on four expression methods: overlap, transformation, modify, and concentration of ambiguous figure and through empirical analysis using SPSS, the effect of four expressions of ambiguous figure on consumers' purchasing behavior was verified based on the AIDA. According to the results,the most notable and most memorable expression methods of consumers appeared in the order of 'modify', 'concentration', 'overlap', 'transformation', and the “concentration” expression method had the greatest impact on consumers' purchasing behavior. Through this, theoretical basics and reference materials that can be referred to in future research on package design were provided.

      • KCI등재

        패키지디자인에서 나타나는 유머 표현이 소비자의 구매행동에 미치는 영향에 관한 연구

        주남(Nan Zhou),오용균(Yong Kyun Oh) 한국디자인리서치학회 2023 한국디자인리서치 Vol.8 No.1

        근, 현대사에 있어서 유머는 정보를 전달하고 표현하는 가장 좋은 방법 중 하나이다. 특히 패키지디자인에서 유머 표현은 소비자의 주의를 즉시 끌 수 있고 소비자가 관심을 갖게 하여 최종 실제 구매까지 점유 욕구를 불러일으킬 수 있다. 그러나 기존의 유머에 관한 연구는 대부분 광고디자인이나 제품디자인에 관한 것이었기 때문에 패키지디자인 분야에서 유머에 관한 연구가 요구되며, 이에 패키지디자인에서 유머 표현이 소비자행동모델(AIDA)에 미치는 영향을 탐구하고자 한다. 따라서 본 연구에서는 선행 이론 연구를 통해 유머 표현을 '대치, 조합, 조작'으로 분석한 후 실제 사례분석을 수행하였으며, 마지막으로 SPSS를 이용하여 회수된 설문데이터를 실증적으로 분석하였다. 최종적으로 패키지디자인의 유머 표현 세 가지 방법은 실제로 소비자의 구매 행동에 영향을 미치며, 그중 가장 큰 영향을 미치는 것은 ‘대치 표현’으로, 향후 패키지디자인에 있어 유머 표현에 관한 참고할 수 있는 이론적 토대를 제공할 수 있을 것이다. Humor is one of the best ways to convey and express information in modern and contemporary days. Particularly in package design, humor expression can immediately attract consumers' attention and arouse consumers' desire to linger (or stick around) until the final actual purchase. However, since most of the existing studies on humor were on advertising design or product design, there are relatively few studies on humor in package design, so this study aims to explore the effect of humor expression on consumer behavior models (AIDA) in package design. In this study, humor expression was analyzed as 'substituting, combining, and manipulating' through prior theory research, and then actual case analysis was performed. Finally, the collected survey data were empirically analyzed by SPSS.25. The three methods of humor representation in packaging design can actually affect consumers' purchasing behavior, but the most influential one is 'substituting', which can provide a reference theoretical foundation for humor representation in future package design.

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