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Endophytic Fungal strains Specifically Modified the Biochemical Status of Grape Cells
Li-Hua Huang,Ming-Zhi Yang,Xiu-Jin Ao,An-Yun Ren,Ming-Quan Yuan,Han-Bo Zhang 한국식물학회 2018 Journal of Plant Biology Vol.61 No.4
Previously, specific interactions in morphologywere observed between grape cells and endophytic fungalstrains during a dual culture experiment. However, thebiochemical impacts of these fungal endophytes on grapecells is also expected due to their potential application in grapequality management. After assessed multiple physiochemicaltraits to those grape cells which have co-cultured with differentendophytic fungal strains in this study, and found the presenceof fungal endophytes obviously triggered ROS stress responsesin grape cells, and the biochemical status in grape cells weredifferentially modified by different fungal strains. In thosetested endophytic fungal strains, RH37 (Epicoccum sp.),RH6 (Alternaria sp.), RH32 (Alternaria sp.) and RH34(Trichothecium sp.) conferred greater metabolic impacts ongrape cells. And soluble protein (SPr), total flavonoids (TF),total phenols (TPh) and malondialdehyde (MDA) on the otherhand, were sensitive biochemical parameters which can beinfluenced in greater ranges than other detected parameters. Most interestedly, fungal endophytes shaped metabolitespatterns in grape cells during the dual culture appeared fungalgenus/species/strain-specificity. The work confirmed thesignificance of fungal endophytes in grape metabolic regulationand elucidated the possibility to purposely manage grapequality using tool of fungal endophytes.
Stability of Hybrid Impulsive and Switching Stochastic Systems with Time-delay
Xuegang Tan,Bin Hu,Zhi-Hong Guan,Rui-Quan Liao,Jiang-Wen Xiao,Yuehua Huang 제어·로봇·시스템학회 2018 International Journal of Control, Automation, and Vol.16 No.4
This paper investigates a model of hybrid impulsive and switching stochastic systems (HISSS) with time-delay. Several stability criteria, including the globally asymptotical and exponential stability criteria in the pth moment and mean square, are established by using Itô formula, a generalized switching Lyapunov functions and some relating techniques. Especially, a more general Lyapunov-Krasivskii functional is constructed, and it is observed that the mean square asymptotic and exponential stability conditions of HISSS are delay-dependent. A numerical example shows that the obtained stability results can reduce the conservativeness.
Huai Chang Yu,Han Dong Liu,Zhi Quan Huang,Guang Cheng Shi 대한토목학회 2017 KSCE Journal of Civil Engineering Vol.21 No.3
Short-term and creep tests were performed on saturated silty mudstone obtained from the Three Gorges Reservoir area. Based on the triaxial creep test results, the variations of creep strain and creep rate of silty mudstone with time were analyzed in detail, and the differences between the axial and lateral creep parameters were quantitatively studied at different deviatoric stress levels. The longterm strength of silty mudstone was obtained. The results demonstrate that the lateral creep characteristics are more significant than the axial creep characteristics for silty mudstone in the tests. Analysis of the lateral creep characteristics of the rock is a reasonable approach to determine whether creep failure occurs in the silty mudstone. The long-term strength of silty mudstone decreases remarkably, and it is actually the lateral long-term strength of the rock. According to the triaxial creep curves of silty mudstone, a new nonlinear viscoelasto-plastic creep model was proposed by connecting in series the nonlinear viscoplastic body with the sixcomponent model. Comparing the model curves with test results, this model was determined to reflect the creep properties of silty mudstone accurately. Finally, the selection of the creep model parameters was achieved by considering the axial and lateral creep characteristics of silty mudstone.
Li, Xin,Wang, Yang,Li, Xing-Wang,Liu, Bao-Cheng,Zhao, Qing-Zhu,Li, Wei-Dong,Chen, Shi-Qing,Huang, Xiao-Ye,Yang, Feng-Ping,Wang, Quan,Wang, Jin-Fen,Xiao, Yan-Zeng,Xu, Yi-Feng,Feng, Guo-Yin,Peng, Zhi-Ha Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5
Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. USP7 is a very important protein with an important role in regulating the p53 pathway, which is critical for genomic stability and tumor suppression. We here genotyped eight SNPs within the USP7 gene and conducted a case-control study in 312 CRC patients and 270 healthy subjects in the Chinese Han population. No significant associations were found for any single SNP and CRC risk. Our data eliminate USP7 as a potential candidate gene towards for CRC in the Han Chinese population.
Liu, Ye-Qing,Li, Hai-Feng,Han, Jing-Jing,Tang, Qiong-Lan,Sun, Qing,Huang, Zhi-Quan,Li, Hai-Gang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12
Background: To investigate the expression of CD44v3 and vascular endothelial growth factor-C (VEGF-C) and their relationship with lymph node metastasis in squamous cell carcinomas (SCC) of the uterine cervix. Materials and Methods: Expression of CD44v3 and VEGF-C was analyzed in 109 cases of cervical SCC by immunohistochemistry (IHC). The relationship was analyzed between expression and the patient age, histological differentiation, formation of tumor emboli in lymphoid vessels, lymph node metastasis, FIGO staging, and TNM classification. Results: Expression rates for both CD44v3 and VEGF-C were 43.1% in cervical SCC. The cells with positive immunohistochemical staining of CD44v3 were distributed mainly around the keratin pearls in well differentiated carcinomas, but distributed diffusely in the moderately and poorly differentiated lesions. VEGF-C was found stained positively in most of the tumor cells. There were differences in expression between normal epithelium and atypical hyperplasia as well as carcinoma. Both CD44v3 and VEGF-C were found to be associated positively with lymph node metastasis and TNM classification (both p=0.000). Neither CD44v3 nor VEGF-C was found to be associated with patient age, histological differentiation, formation of tumor emboli in lymphoid vessels and FIGO staging. CD44v3 was found to be associated with VEGF-C positively (p=0.000). Conclusions: Abnormal expression of CD44v3 and VEGF-C is associated closely with the lymph node metastasis in cervical SCC, and these agents may cooperate in carcinogenesis and development of metastatic lesions.