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Kim Chong-Gi(김정기),Yu Bae-Gun(류배건) 한국체육과학회 2010 한국체육과학회지 Vol.19 No.2
The purpose of this study was to investigate whether or not GNB3 C825T gene polymorphism was associated with abdominal obesity and obesity-related metabolic syndrome markers in Korean women (N=l04) and whether or not GNB3 C825T gene polymorphism would modulate obesity and its metabolic syndrome markers' responses to 12 weeks of dance sports program in the same study population. The following results were found in this study: 1) at the baseline measurements, the GNB3 genotype was not significantly associated with any of the measured variables; 2) the GNB3 genotype was a significant modulator in determining some of the responses of the metabolic syndrome markers (i.e, cardiorespiratory fitness, TG, insulin and HOMAIR) to 12 weeks of dance sports programs; and 3) the GNB3 genotype didn't modulate blood pressures responses to 12 weeks of dance sports program. In conclusion, the current findings of the study suggest that GNB3 C825T gene polymorphism can partially be a genetic modulator of obesity and modulate related metabolic syndrome markers' responses to exercise training in this study population.