Trigger point를 利用한 口眼괘斜 患者 10例에 대한 臨床的 考察

鄭榮敦,李浚龜,金永一,朴泰均,辛泳一,黃載然,李賢,李秉烈 대전대학교 한의학연구소 2002 한의학연구소 논문집 Vol.10 No.2

From July 1th 2001 to October 31th 2001, the Clinical investigation studies were carried out 10 cases of patient with Bell's palsy using Trigger point treatment group, who had been treated in Han-seung Oriental Medical Clinic. The results were like below : 1. The distribution of sex : Male were 4cases, female were 6case and the female to male ratio was 1.5 : 1. 2. The distribution of contributing factor : Unknown reason was most predominant 4 cases, and then were revealed to labor too hard, menttal stress(3 cases), trauma·common cold(1 case) in turn. 3. The distribution of perid to fall ill : Under a week was the most number 6cases, and then were revealed a week under two weeks(3 cases), over two weeks(1 case) in turn. 4. About period of treatment : The Trigger point treatment group is shorter than the Acupuncture treatment group. 5. The distribution of grade on admission in descending order : GrⅠ was the most number and then GrⅡ, GrⅢ in turn. 6. The distribution of clinical symptoms on adimission : Mastoid pain was the most number 9 cases and then lacrimal gland disorder 8 cases, dysgeusia 4 cases, hyperacusis 2 cases, the others 2 cases in turn. 7. About effect of treatment : The Trigger point treatment group is more excellent than the Acupuncture treatment group. 8. The more patient age is young, the more effect of treatment was excellent, had nothing to do with both groups. 9. The more perid to fall ill is short, the more effect of treatment was excellent, had nothing to do with both groups. 10. About period of improved frontal belly : The Trigger point treatment group is more excellent than the Acupuncture treatment group.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

BMB Reports : Binding model for eriodictyol to Jun-N terminal kinase and its anti-inflammatory signaling pathway

( Eun Jung Lee ),( Ki Woong Jeong ),( Areum Shin ),( Bong Hwan Jin ),( Hum Nath Jnawali ),( Bong Hyun Jun ),( Jee Young Lee ),( Yong Seok Heo ),( Yang Mee Kim ) 생화학분자생물학회 2013 BMB Reports Vol.46 No.12

The anti-inflammatory activity of eriodictyol and its mode of action were investigated. Eriodictyol suppressed tumor necrosis factor (mTNF)-α, inducible nitric oxide synthase (miNOS), interleukin (mIL)-6, macrophage inflammatory protein (mMIP)-1, and mMIP-2 cytokine release in LPS-stimulated macrophages. We found that the anti-inflammatory cascade of eriodictyol is mediated through the Toll-like Receptor (TLR)4/CD14, p38 mitogen-activated protein kinases (MAPK), extracellular-signalregulated kinase (ERK), Jun-N terminal kinase (JNK), and cyclooxygenase (COX)-2 pathway. Fluorescence quenching and saturation-transfer difference (STD) NMR experiments showed that eriodictyol exhibits good binding affinity to JNK, 8.79 × 105 M-1. Based on a docking study, we propose a model of eriodictyol and JNK binding, in which eriodictyol forms 3 hydrogen bonds with the side chains of Lys55, Met111, and Asp169 in JNK, and in which the hydroxyl groups of the B ring play key roles in binding interactions with JNK. Therefore, eriodictyol may be a potent anti-inflammatory inhibitor of JNK. [BMB Reports 2013; 46(12): 594-599]

대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

아로니아 잎의 성숙도에 따른 항산화 물질 조성 및 항산화 능력

양해조(Haejo Yang),박현정(Hyunjeong Park),윤형열(Hyeongyeol Yun),김영준(Young-Jun Kim),신영재(Youngjae Shin) 한국식품과학회 2021 한국식품과학회지 Vol.53 No.2

국내에서 재배한 A. melanocarpa 잎의 성숙도에 따른 이화학적 특성 변화, 항산화 물질 조성 변화 및 항산화 능력과 같은 기능적 특성을 분석하여, 아로니아 잎의 성숙도별 이용 가능성을 확인하였다. A. melanocarpa 3품종의 잎의 폴리페놀, 플라보노이드, 페놀화합물 함량은 성숙이 진행될수록 감소하였고, 항산화물질과 상관관계가 높은 ABTS 라디컬 소거능 및 DPPH 라디컬 소거능 역시 감소하는 경향을 보였다. 현재, 블루베리는 잎과 열매 모두 식품원료로 등록되어 있으나, 아로니아의 경우는 식품의약안전처에서 고시한 식품원료목록 상 열매 부위만 등록되어 있는 실정이다. 아로니아 잎에는 chlorogenic acid와 catechol이 다량 함유되어 있고, 아로니아 잎의 항산화 능력은 기타 베리류와 비교하였을 때, 상당히 높은 수준인 것으로 확인된 바와 같이, 아로니아 잎은 향후 가공 식품 이외에 다양한 분야로의 활용 가능성이 충분할 것으로 판단된다. In this study, the leaves of aronia (Aronia melanocarpa) across different stages of maturity were collected and their chlorophyll content, antioxidant content, and activity were analyzed. The leaves of the selected aronia cultivars (‘Viking’, ‘McKenzie’, and ‘Kingstar K1’) were harvested in June (young-stage leaf) and in August (old-stage leaf). The antioxidant content and activity of all three aronia cultivar leaves were significantly higher in the young-stage leaves than in the old-stage leaves. The main polyphenols in aronia leaves were catechol and chlorogenic acid, which tended to decrease as maturation progressed. As a result, the young-stage aronia leaves contained more abundant flavonoids, phenolic compounds, and polyphenols with higher antioxidant activity than those in the old-stage leaves. Overall, our findings indicate that aronia leaves contain potential bioactive compounds that could be used to develop functional food ingredients.

쓰레기 매립장 주변 농촌 주민들의 삶의 질 연구

이명경,최준열,김인경,조영아,김영신,정혜진,김리나,이영규,조영태,Lee, Myung-Kyung,Choi, Jun-Yeol,Kim, In-Kyoung,Cho, Yeong-Ah,Kim, Young-Shin,Jung, Hye-Jin,Kim, Li-Na,Lee, Young-Kyu,Cho, Young-Tae 대한예방의학회 2006 예방의학회지 Vol.39 No.4

Objectives: This study aims to examine if a garbage dumping site has real and negative influence on the quality of life (QOL) for the nearby residents. The net effects of the residential distance from the garbage dumping site and from the garbage truck route were investigated for five domains of the QOL. Methods: Two hundred fifty seven Shin-dong Myeon residents, Chun-cheon Si, participated in a self-administrated survey. The Shin-dong Myeon garbage dumping site began operating in 1996. ANCOV A with generalized linear models and multiple regression analysis were performed. Results: Descriptive analyses show that a residence nearby a garbage dumping site is negatively associated with the physical and environmental domains of the QOL. The residential distance from the garbage truck route does not exert any significant effect on various domains of QOL, except for the environmental domain. On the multivariate analysis, the residents living near the garbage dumping site tended to have a significantly negative QOL in the physical and environmental domains. However, the distance from the garbage truck route did not show a significant nor substantial effect on the QOL. The demographic and socioeconomic control variables are associated with a number of the QOL domains, and their patterns are consistent with the general expectations. Conclusions: The results indicated that a garbage dumping site is considered to be an environmental hazard among the nearby residents according to the lower scores on the physical and environmental domains of the QOL. The findings from this study provide comprehensive understanding on the residents' QOL, and they may help politicians and policy makers make decisions for appropriate interventions.

합금철 분진의 재활용을 위한 기초 연구

신강호,송영준,김윤채 三陟大學校 1998 論文集 Vol.31 No.1

This study was performed to obtain the basic data for recycling of the dust in ferroalloy manufacture. The chemical composition, composition material, particle size and shapes of the bulk dust, sizing dust and magnetic separating dust were investigated. As the result, the dust from High Carbon Ferromanganese Manufacturing Process is not sufficient as source material of Mn, the dust from Bag Filter of AOD Process is a good source material of Mn, and the dust from Cooler of AOD Process can be a good source material of Mn through Sizing or Magnetic Separation.

자가지방을 이용한 성대주입술

손영익,박주현,이은경,신준호,추광철 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.12

가토의 뇌동맥류 모형에서 모동맥 및 동맥류 협자에 따른 동맥류 내압의 변화 :기초 연구

김은영,송준혁,김명현,박향권,김성학,신규만,박동빈 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.4

의무행정과 교과과정 개발을 위한 선행연구

신종연,윤병준,김영훈 서울保健大學 1993 論文集 Vol.13 No.1

This study was carried out to develope the educational program of medical administration department, Seoul Health Junior College. For this study, educational subjects were derived from the job division analysis of a hospital(1200 beds teaching hospital). Questionaires were sent to the 150 numbers of graduates who finished the course of the above department from 1983 to 1992, and who are now employed in hospitals. Also other questionairs were sent to the chiefs of medical record, medical insurance, and hospital affairs departments in 120 numbers of teaching hospitals accredited by Ministry of Health & Social Affairs. The answers from 109 graduates and 86 department chiefs have been actually surveyded. 1. General characteristics It was found that female respondents were 77%, the respondents under 30 years of age were 81.6%, and 67.9% of the 109 respondents were employed in hospitals with over 300 bed capacity. The largest number of respondent(34.9%) were employed in the hospitals run by educational foundations, the smallest numbers(10.1%) were in national & public hospitals. The classification by the working period showed that the workers under two years of period had the higest rate(40.4%) and the workers over 6 years of period had the second rate(27.5%) Their major working fields in the hospitals were the departments of medical record(32.1%), hospital affairs(27.5%), and medical insurance (21.1%), respectively. 2. Degree of job difficulty When the difficulties of the job performed by the respondents were categorized into difficulty, moderate, easy, the proportion of the moderate job in which more respondents were actually working was found to be much larger that of moderate job classified by job analysis. Job difficulties classified by working fields were not statistically significant. 3. The utilization of professional knowledge 68.8% of respondents think that their professional knowledge is practically utilized. The utilization of professional knowledge classified by difficulty of job, the more difficulty the job is, the more utilized the professional knowledge is. The utilization of professional knowledge by working period, it is statistically significant for the respondents of over 5 years of period compared with those of under 5 years of period. 4. The satisfaction with professional knowledge When the utilization of and the satisfaction with their professional knowledge were compared, their patterns(the percentage of respondent) appeared to be almost the same in bed capacity, working-fields, degree of job difficulty, the duration of work period, but the satisfaction was considered to be lower than utilization in all above variables. 5. Subjects of study needed in fields Professional knowledge in medical terminology, practicum of medical insurance, and ICD coding were necessary in carrying out their works. Also graduates wanted to study more about practicum of medical insurance, computer science, and clinical pharmacology respectively. The graduates in hospitals wanted to study more about the subjects such as hospital planning, hospital marketing, employer & labor relations, purchasing management, but these subjects are excluded from the curriculum of medical administration department as a single subject. 6. Training & QJT after graduation 60.6% of respondents had the intensive training to make themselves familiar with the professional work after graduation. Computer fields commomly required more training(40.9%) and the training period was usually 2~3 months(46.9%). 36.7% of the surveyed graduates were job-trained and the larger the bed capacity was, the more OJT was given. The subjects most frequently studied in OJT were firstly the reimbursement of medical insurance and secondly computer science. The effect of OJT is positive in recognition of facts and rules, in behavior changes, in cost reduction and improving job practice. 7. Continuing education Korea air and correspondence university was preferred in order to continue education but this educational experience was not much useful for their professional jobs in general. So the need of continuing education in connection with their practical jobs was very high(74.8%) and 76.2% of surveyed graduates intend to participate in program if the above continuing education program is provided in the junior college. 8. Evaluation of hospital practicum The effect of hospital practicum in college according to the graduates' opinion was moderate degree and the first negative reason against hospital practicum was the unfaithful behavior of the hospital personnels toward the students. 44.2% of department chiefs in hospitals think that practicum period(3~4weeks) was not adequate. 23.2% of chiefs think that the practicum season(summer vacation) was not adequate, because they are very busy due to the summer vacation of hospital personnels and the increase of hospital patients. So they don't have enough time to teach students in that season. 82.6% of chiefs gave job orientation to students and 71% of them trained the students according to systemic teaching schedule including all the aspects of works of departments and only 58.1% checked the reports submitted by students at the end of their practicum. 9. Extending of hospital practicum period The opinion about extension of hospital practicum period to 2∼3 months was recognized positively by 47.7% of departments chiefs. The reasons for the extension were that hospitals should have enough time for their educational responsibility and through their adequately long training course can choose the capable personnel. The preliminary requirement for the extension of hospital practicum period are the development of practicum programs and evaluation devices, the consideration of hospital top manager about the educational function of practicum, and the question of practicum fee. 10. The systems of promoting the efficiency of hospital practicum suggested by department chiefs were: 1) to change the 2 year course of the medical administration department into the 3 year course, and make the hospital practicum of the last term an obligation. 2) to give the credits of hospital practicum in current educational system. 3) to extend the current practicum period. 4) to consider the internship in the certain hospitals after graduation. As a result of the study, the educational program of medical administation department should be devised to promote the followings: 1. In order to meet the satisfaction of professional knowledge, quantitative & qualitative chance for studying the subjects necessary for practical job should be strengthened. 2. In the revision of the curriculum, the inclusion of the subjects the respondents want to study as a single subject should be considered. 3. In order to promote the efficient continuing education for the graduates, the chance of education program for further study should be provided in junior college. 4. The actual problems arising in the current hospital practicum should be recognized, the alternative improvement should be sought. 5. In stead of depending upon the partial changes of curriculum, the total educational program should be reformed to get rid of current problems and forecast the future need.