습관성 흡연여성에서 후측 수부에 발생한 Buerger씨병

김삼,이남호,육청미,최영진,백대균,홍경순,두영철,한규록,오동진,유규형,임종윤,이광학,이영 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.7

디지털다중서명을 이용한 이동에이전트 보안시스템의 설계

유성진,정일용,김영철 조선대학교 전자정보통신연구소 2002 電子情報通信硏究所論文誌 Vol.5 No.1

Mobile agent system comes into the spotlight since it contributes largely to mobile computing on distributed network environment. However, this system has a number of significant security problems. In this paper, we analyze security attacks to mobile agent system presented by NIST[3]. In order to protect this system from them, we suggest a security protocol for mobile agent system by employing ID based key distribution and digital multi-signature scheme. To solve these problems described on NIST, securities of mobile agent and agent platform should be accomplished. Comparing with other protocols, our protocol performs both of these securities, while other protocols mentioned only one of them. Furthermore, it is designed to guarantee the liveness of agent, and to detect message modification immediately by verifying each step of agent execution at a corresponding server.

간경변증 환자의 정신과적 특성 및 아임상적 간성뇌병증 진단을 위한 연구 : 인지기능 및 유발전위를 중심으로 Cognitive Functions and Evoked Potentials

유승호,이소영,김진세,변관수,정인과 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.5

연구목적 : 본 연구는 명백한 간성뇌병증이 없는 간경변증 환자에서 불안, 우울기분 및 삶의 질 등 정신과적 특징과 신경심리학적인 결손의 양상을 밝히기 위해서 고안되었다. 그리고 아임상적 간성뇌병증의 평가에서 체성감각 유발전위 검사의 역할을 연구하고자 하였다. 방 법 : 간경변증으로 진단된 41명의 환자군과 정상 대조군 31명을 대상으로 하였다. 이들에서 우울기분 및 불안을 평가하기 위해 Beck Depression Inventory와 State & Trait Anxiety Inventory를 시행하였고 삶의 질의 평가를 위해 Health-related Quality of Life Questionnaire를 시행하였다. 또한 어휘검사, 숫자외우기 검사, 토막짜기 검사, 숫자기호 바꿔쓰기 검사 및 선로잇기 검사 A와 B 등 간단하지만 포괄적인 인지기능검사를 시행하였다. 또한 41명의 환자군 중에서 인지기능검사 결과에 의거하여 분류된 13명의 아임상적 간성뇌병증군(SHE군)과 11명의 아임상적 간성뇌병증이 아닌 간경변증 환자군(non-SHE군) 그리고 8명의 정상 대조군에서 체성감각 유발전위를 측정하였다. 결 과 : 간경변증 환자는 정상인에 비해서 우울기분과 특성불안이 유의하게 증가하였다. 또한 건강과 관련된 일상생활의 삶의 질의 수준이 정상인보다 저하되었고, 특히 주의력과 각성이 요구되는 행동에서 수행이 저하되었다. 또한, 간경변증 환자는 숫자기호 바꿔쓰기 검사와 선로잇기 검사에서 정상 대조군보다 저하된 수행을 나타내었다. 또한 이러한 인지기능검사를 통해서 진단한 아임상적 간성뇌병증군에서 6개월 추적조사를 하였을 때, 명백한 간성뇌병증의 빈도가 아임상적 간성뇌병증이 아닌 군보다 유의하게 높았다. 체성감각 유발전위 소견은 N65 잠복기와 N20-N65 IPL의 경우 SHE군, non-SHE군 및 정상 대조군 사이의 유의한 차이가 있었다. 특히 N65는 SHE군만이 정상 대조군과 유의한 차이가 있었고 N95는 숫자기호 바꿔쓰기 검사 및 선로잇기 검사 A와 유의한 상관관계가 있었다. 결 론 : 간경변증 환자에게 우울 및 불안 등 정서적인 어려움에 대한 실제적인 관리 및 삶의 질을 높일 수 있는 치료적 접근이 고려되어야 하겠다. 또한 숫자기호 바꿔쓰기 검사와 선로잇기 검사가 아임상적 간성뇌병증의 조기 진단에 민감하고 유용한 도구로 생각되어 간경변증 환자에서 정례적으로 적용시키는 것이 간경변증 환자의 관리에 도움을 줄 수 있을 것으로 생각된다. 마지막으로, 본 연구에서의 체성감각 유발전위 소견은 간경변증 환자에서 아임상적 간성뇌병증 환자의 진단 및 연구에 중요한 의미를 지닌다고 생각된다. Objectives : This study was designed to elucidate the psychiatric characteristics and nature of the neuropsychological deficits associated with subclinical hepatic encephalopathy(SHE) in patients with non-alcoholic liver cirrhosis. And also the authors prospectively studied the role of somatosensory evoked potentials(SEP) in the assessment of SHE. Methods : Beck Depression Inventory(BDI) for measuring depression, State Trait Anxiety Inventory(STAI) for measuring anxiety, and Health-related Quality of Questionnaire(HQLQ) for measuring quality of life were administered the 41 non-encephalopathic liver cirrhosis patients(NELC) group and 31 carefully matched normal controls. And a prospective study to compare the performance of NELC group and normal controls on a short but comprehensive cognitive tests was conducted. After several cognitive, NELC group was divided into two groups, SHE group and non-SHE group by results of digit symbol substitution test(DSST) and/or trail making test(TMT) A and B. And then median nerve evoked cortical responses in 13 SHE patients group, 11 non-SHE patients group, and 8 normal controls were recorded for latencies of N13, P16, N20, P25, N30, P45, N65, and P95. And also responses for N13-N20 interpeak latency(IPL) and N20-N65 IPL were recorded. Results : There were significant differences between the NELC group and normal controls on BDI, trait anxiety scales in STAI, and almost all HQLQ except for the cognitive function, social interaction and life satisfaction(p<0.05). The NELC group exhibited poor performance in DSST, TMT A and TMT B compared with normal controls(p<0.05). As 17 NELC patients had abnormal cognitive test results, 41.5% of cirrhotic patients had SHE. In SEP assessment, NELC group with SHE and without SHE had higher N20-N65 IPL and only NELC group with SHE had higher N65 latency compared with normal controls(p<0.05). Conclusion : This study suggests that the patients with liver cirrhosis exhibit relatively selective deficits in complex attentional and fine motor skills, with preservation of general intellectual ability, memory, language and visuospatial perception. DSST, TMT A and TMT B seem to be useful screening tests for the detection of SHE. And also it is expected that late components and N20-N65 IPLs of SEP are helpful in the assessment of SHE.

하이퍼 큐브네트워크를 이용한 Radiance Estimation 프로세서의 설계

류현우,김영진,이현수 경희-다반 ASIC 설계교육센터 2005 경희-다반 ASIC센터 논문집 Vol.6 No.-

본 논문에서는 Radiance Estimation 연산에 존재하는 전역적인 병렬성을 처리할 수 있는 구조를 제안한다. 기존의 소프트웨어 처리는 계산에 필요한 많은 연산의 시간이 필요로 하기 메문에 하드웨어 적인 구현의 필요성이 증대하였다. Radiance Estimation 알고리즘의 병렬성을 이용하여 SIMD 처리 방식으로 설계를 하였으며 연산의 단위인 Cell의 통신은 4차인 하이퍼 큐브 네트워크를 이용하여 데이터간의 효율성은 높였다. 그리고 연산의 신호에 따라 다양한 기능을 하는 Cell로 구성을 하여 Radiance Estimation 연산의 Photon 검색과 밀도추정 연산을 하나의 시스템에서 적용이 가능하였다.

해양에서 분리한 Bacillus subtilis SH-1이 분비하는 용균효소의 정제 및 특성

진성현,정영기,류병호 동의대학교 기초과학연구소 1997 基礎科學硏究論文集 Vol.7 No.1

The Research Institute for Basic Sciences DongEui UniversityThe Research Institute for Basic Sciences DongEui University

공간 상징을 통해 본 방랑의 모티브 : Wilhelm Meisters Wanderjahre를 중심으로

류영진 한국괴테학회 2002 괴테연구 Vol.0 No.14

Das Wander-Motiv ist ein biliebtes Motiv in der Literaturgeschichte, besonders bei Goethe. Er griff ha¨ufig dieses Motiv auf und verwendete in verschiedenen Werken, in lyrischen und epischen Gattungen. Aus den zahlreichen Werken ragt der Roman Wihelm Meisters Wanderjahre mit seiner Intensita¨t und Virtuosita¨t hervor. In den Wanderjahren ero¨ffnet sich eine erweiterte Raumgestaltung. Und die ausfu¨hrlich dargestellten Ra¨urne enthalten jeweilig symobolisch Zu¨ge, die mit dem Sinn des Wanderns im engen Zusammenhang stehen. In dieser Hinsicht Wurde es hier versucht, das Motiv des Wanderns durch Raumsymbolik neu zu beleuchten. Zuna¨chst stellt das Gebirge die Trennung Wilhelms von seiner Geliebten, Natalie symbolisch dar. Diese Trennung bedeutet ihm Entsagung, die als das Hauptthema den ganzen Roman durchziegt. Zweitens, das Schloβ von Makarie symbolisiert mitdessen Turm den Heiligtum, geistliche Hoheit, welches wiederum mit dem Charakter der Hausherrin u¨bereinstimmt. In dieser Station wird Wilhelm von Makarie und ihre Wirkung tiefst beeindruckt, sodaβ er seine neue Lebensaufgabe unter den Mitmenschen erkennt. Drittens, die Pa¨dagogische Provinz ist das Symbol fu¨r Utopie der Erziehung. Ihre erzierische Ideologie beruht auf die dreifache Ehrfurcht und den Utilitarismus. In dieser Gegend betrachtet Wilhelm, wie sich der Mensch mit seiner handwerklichen Arbeit vorbereitet, um den anderen nu¨tzlich zu werden. Zuletzt funktioniert Lago Maggiore als ein Ort der Selbstreflexion und geistlicher Wiedergeburt. Hier auf dem See sieht Wilhelm sich sein Innere ein, das mit dem bitteren Gedenken der Toten (Mignon und die Fischerknaben) erfu¨llt ist. Nach der Reflixion stellt er sich fest, Wundarzt zu lernen und damit die Mitmenschen zu bedienen. Dieser Denkprozeβ bezieht sich auch auf das Symbol der Raumstruktur, na¨mlich das Symbol von See und Wasser. Aus dieser Auseinandersetzung mit der Raumsymbolik schluβfolgert, dass Wilhelms Wanderschaft mit dem Ortswechsel immer tiefere Bedeutungen tra¨gt, und diese Bedeutungen durch die Symbol interpretation der Raumgestaltungen erhoben werden. Angefangen mit der Wanderuns als Entsagung findet Wilhelm allma¨hlich durch den langen Bildungprozeβ seine wahre Identita¨t und Sendung, indem er an mehreren bedeutungsvollen Stationen voru¨bergeht. Also, der Sinn des Wanderns integriert sich in Reife, die sich erst durch Ehrfurcht u¨ber Menschen bzw. Hingabe fu¨r Menschen erreichen la¨βt.

대전공단지역의 대지중 독성 금속의 농도 분석

류영태,남병현,이진흥 忠南大學校 環境問題硏究所 1997 環境硏究 Vol.15 No.-

In spite of lower concentration of toxic metals in urban air, the magnitude of health risk associated with may not be smaller than that by other airborne hazardous pollutants. Especially, it has been expected that the risk from an industrial complex may be much higher by toxic metals including carcinogenic ones. However, unfortunately there has been few domestic research on the concentration profile and risk assessment of airborne toxic metals in such area. The reason may be that the final objective of studies performed before for our urban air was either source characterization or quantitative source estimation of suspended particulate matter and development of a receptor model. Thus, few investigation into the concentration distribution for toxic metals such as As, Be , Cr, Ni, Se, Sb and V has been done. Therefore, this research will focus on 2-year- analysis(twice or four times per month) by using ICP-MS and ICP-AES for the concentration of heavy metals in Taejon Industrial Complex. ICP-MS has much more excellent detection limits and reproducibility for many toxic metals than any other analytical technique. Total suspended particulates were collected on quartz fiber filters by a high volume air sampler. About 20 metal elements including 13 toxic ones were analyzed by ICP-MS and ICP-AES after the pretreatment of mixed acid extraction. As a part of the research, the following results for the period of from June to August, 1997 were summarized : (1) the geometric mean concentration of TSP was 87.28㎍/㎥ during the sampling period in the study area. The maximum was 114.16㎍/㎥ in the 4th week of August while the minimum was 47.97㎍/㎥in the first week of August; (2) much higher concentrations of Pb and Zn were noted among toxic metals and their geometric means were 288.31ng/㎥ and 153.47ng/㎥, respectively. The highest concentration of Pb was 570.99ng/㎥ in the 4th week of August while that of Zn was 279.03 ng/㎥ in the first week of June;(3) the concentration of each Ni, Mn, Zn and Fe was found to be highly correlated with that of TSP, which indicated the greater impact of man- made pollution in the area. The concentration of elements such as Al, Ca and Mg related to soil and road dust was found to be the highest in June and their correlation coefficients were estimated to be very high.

유방암 환자에서 bcl-2 단백 발현의 예후 인자로서의 의의

류진우,박종권,정민,박동국,김정택,이두선,이찬영,전호진 단국대학교 1998 論文集 Vol.32 No.-

Breast cancer in women pose a problem, and it can be difficult at times to evaluate the possibility of the cancer recurrence in node negative early cancer. The reliable prognostic markers are needed in breast cancer management to help clinicians identify the patient with the high risk of recurrence and arrive at more rational decisions for proper treatment. In order to investigate the prognostic significance of bcl-2, an immunohis-tochemical staining was performed in 35 tissue sections from paraffin blocks of primary breast cancer. Bcl-2 positivity was 43%. No relation could be observed between bcl-2 expression and known prognostic factors(tumor size, lymph node metastasis state, histologic grade, and nuclear grade), There was strong relation between bcl-2 expression and estrogen receptor positivity (ER) (P〈0.05). No relation is found between bcl-2 expression and c - erbB - 2 expression. These results suggest that bcl-2 expression is associated with a favorable prognostic factor(ER) but it is of no value as independent prognostic factor to the clinician in identifying the patients with high risk of recurrence.

Mycobacterium abscessus에 의한 슬관절 감염1예

류숙원,이창규,허진,신규성,김장수,배숙영,장은아,서인범,김영기,이갑노 대한임상병리학회 2001 대한임상병리학회지 Vol.21 No.5

참돌꽃 근경의 항산화작용

류광열,강원식,김영호,장해동,홍진태,유환수,윤여표 충남대학교 약학대학 의약품개발연구소 1998 藥學論文集 Vol.14 No.-

The purpose of this study was to determine the antioxidative effects of Rhodiola sachalinensis Rhodiola methanol extract was fractionated sequentially with dichloromethane and butanol. Each Rhodiola fraction (water, MeOH, BuOH and CH_2Cl_2 fractions) showed the potent superoxide dismutase (SOD) activity, and had inhibitory effets on peroxide value of linoleic acid (40~57%) and lipid peroxidation (47~70%) in FE^2+/ascorbate system-induced rat liver microsome. Rhodiola methanol extract also recovered carbon tetrachloride-induced decrease in SOD by 42% and catalase activities by 50%, and had inhibitory effects (54%) on carbon tetrachloride-induced lipid peroxidation in rat liver microsome. These results suggest that Rhodiola sachalinensis has the antioxidative effects.