연령대별 요추 추간판탈출증 환자의 요근과 척추주위근 단면적에 대한 분석

공덕현 ( Deok Hyun Kong ),배광호 ( Kwang Ho Bae ),고호연 ( Ho Yeon Go ),강명진 ( Myung Jin Kang ),김준수 ( Jun Su Kim ),양기영 ( Kee Young Yang ),이재훈 ( Jae Hoon Lee ),은영준 ( Young Jun Eun ) 한방재활의학과학회 2010 한방재활의학과학회지 Vol.20 No.4

Objectives :This study was designed to evaluate the correlation of the cross-sectional areas(CSA) of paraspinalis(iliocostalis lumborum, multifidus, longissimus thoracis parts lumborum) and psoas muscle and sex, age, change of the VAS(visual analogue scale) and past history of chronic low back pain in patients suffering from HIVD(herniation of intervertebral disc). Methods :Medical records of 140 subjects with HIVD were retrospectively reviewed. The MRI(magnetic resonance imaging) findings on the patients were scanned and analyzed by PiView program to find the paraspinal and psoas muscle CSA and were evaluated by the correlation of sex, age, change of the VAS, and past history of chronic low back pain. Results :There was significant difference between groups in male and female, young-adults age and middle age, middle age and old age, young-adults age and old age. But the correlation of the paraspinal and psoas muscle CSA and past history of chronic low back pain were partially significant. On the other hand, the correlation of the paraspinal and psoas muscle CSA and change of the VAS were not significant. Conclusions :These results suggest that the cross-sectional areas(CSA) of paraspinalis and psoas muscle have relevance to sex and age.

설치류 뇌에서 c-Fos를 이용하여 삼투조절과 관련된 신경회로의 규명

이영기,박덕배,장가용 제주대학교 생명과학연구소 2000 제주생명과학연구 Vol.3 No.-

본 연구는 생쥐의 중추신경계통에서 고장액에 반응하여 c-Fos에 대한 면역양성을 나타내는 지역을 규명하고자 수행하였다. c-Fos의 발현은 면역조직화적으로 검출하고 신경세포의 활성화에 대한 표식자로 이용하였다. 고장액은 생쥐 뇌의 supraoptic nuclus, median preoptic nucleus organum vasculosum lamina terminalis, sufornical organ, locus coeluleus, nucleus of solitary tract, ventrolateral medulla, parabrachial nucleus 등에서 발현되었다. 특히 retrochiasmatic area의 배쪽 부분에서 많은 c-Fos면역양성의 세포가 관철되었으며, 시상하부의 paraventricular nucleus나 두뇌의 area postrema에서는 c-Fos면역양성세포가 거의 관철되지 않았는데 이들 지역들은 흰쥐에서는 다수의 c-Fos면역양성 세포가 나타나는 지역이다. 이상의 결과들은 생쥐에서 고장액이에 의해 c-Fos면역양성 세포가 나타나는 지역은 흰쥐에서와는 일부 상이한 결과를 보여주는 것으로 나타났다. Experiments were carried out on adult mouse to investigate the regional localization of the cells inducing c-Fos immunoreactivity in central nervous system in response to hypertonic saline(HS). c-Fos induction, detected immunohistochemically, was regarded as a marker for neuronal activation. Intraperitoneal injection of HS resulted in dense c-Fos-like immunoreactivity (FLI) in several forebrain and brainstem area. These areas include the supraoptic nucleus(SON), median preoptic nucleus (MnPO), organum vasculosum lamina terminalis(OVLT), subfornical organ(SFO), locus coeruleus(LC), nucleus of solitary tract(NTS), ventrolateral medulla(VLM), and parabrachial nucleus(PBN). In particular, the ventral region of retrochiasmatic area showed numerous and very intensely labeled FLI cells. No FLI or few FLI cells were, however, detected in the hypothalamic paraventricular nucleus (PVN) and the area postrema(AP) respectively, the regions which revealed very intensive FLI in rat after HS treatment. These data suggest that FLI induced in response to osmotic stimuli in the mouse brawn has a different regional distribution from that of rat brain.

모성 직업활동이 조산과 저체중출생 및 자연유산에 미치는 영향

신용덕,이태용,이영수,이동배 大韓産業醫學會 1994 대한직업환경의학회지 Vol.6 No.1

모성 직업활동이 조산, 저체중 출생아 및 자연유산에 미치는 영향을 알아보기 위해 1991년 1월부터 1992년 12월까지 대전에 위치한 C대학병원에서 출생한 1,646명의 산모를 대상으로 하여 조사한 결과는 다음과 같다. 1. 조사 대상자 1,646명의 산모중 임신중 직업을 가진 군이 20.3%, 직업을 갖지않은 군이 79.7%였으며, 직업여부의 분포에 통계적으로 유의한 차이를 보인 변수는 산모의 연령, 교육정도, 임신전 체중, 신장, 유산횟수였다. 2. 임신중 직업을 가진군의 평균 임신기관과 조산율은 39.1주, 7.8%였고, 비직업군은 39.0주, 9.7%였다. 직업군에서 평균 출산아 체중과 저체중 출생아율은 3.228g, 5.4%였고 비직업군은 3,140g, 10.6%였으며, 통계적으로 유의한 차이를 보였다(p<0.05). 평균 자연유산 횟수와 자연유산 경험율은 직업군이 0.2회, 15.0%, 비직업군이 0.3회, 17.4%였다. 3. 연령이 35세 이상, 미숙아 출산력이 있는 경우 및 유산횟수가 2회 이상인 경우는 직업군의 조산율과 저체중 출생아율이 비직업군에 비해 높았으나 통계적 유의성은 없었다. 산과적 합병증이 없는 경우 조산율이 직업군에서 비직업군보다 높았으나 역시 통계적 유의성은 없었다. 4. 자연유산 경험률은 연령이 35세 이상, 학력이 중졸 이하 및 고졸, 산모의 신장이 163cm이상에서 직업군에서 비직업군보다 높게 나타났으나, 통계적 유의성은 없었다. 5. 조산과 관련성이 있는 요인의 영향을 고려했을 때 직장활동군에서 조산의 위험도가 낮았으나 통계적 유의성은 없었다. 6. 임신주수 및 저체중 출생에 관련이 있는 요인의 영향을 고려한 후 직업군에서 저체중 출산의 위험도가 낮았으며 통계적 유의성을 보였다(p<0.05). 7. 과거 유산에 관련이 있는 요인의 영향을 고려한 경우 직업군에서 유산경험율이 낮았으나 통계적 유의성은 없었다. 8. 직업이 교사, 의료인, 은행원, 공무원인 군은 비직업군보다 조산율과 저체중 출생아율이 낮았으며, 회사원은 비직업군에 비해 조산율은 낮았으나 저체중 출생아율은 높았다. 상업군은 조산율과 저체중 출생아율이 15.2%로 비직업군 및 다른 직업군보다 비교적 높았다. 유산경험율은 은행원, 의료인,공무원에서는 비직업군의 17.0%보다 낮았으나, 교사군과 회사원은 17.8, 17.9%로 높았고, 상업군은 33.3%로 다른 직업군에 비해 현저히 높았으며 비직업군에 비해 교차비가 1.42로 통계적 유의성이 있었다(p<0.05). To investigate the effect of maternal job activity on the preterm delivery, low birth weight infant and spontaneous abortion, 1646 delivery data were analyzed from Jan. 1991 to Dec. 1992 in Chungnam University Hospital. The results obtained were as follows; 1. The percentage of subjects who had job during pregnancy was 20.3% and the variables of maternal age, education level, prepregnancy weight, maternal height, number of abotion showed significant difference in the distribution of subjects whether they had job or not. 2. There were no significant difference between the group who had job during pregnancy and those who had no job in the mean gestational period, number of spontaneous abortion, rate of preterm delivery and spontaneous abortion. However mean birth weight and rate of low birth weight showed significant difference between the groups. 3. The rate of preterm delivery of the group who had job were higher than those who had no job activity in the subgroup of 35 years or more age, prematurity history presence, 2 or more abortion history, obstetric complication presence, but there were no significant difference. The rate of low birth weight also higher in the group who had job than those who had no job activity in the same subgroup except obstetric complication presence. 4. The rate of spontaneous abortion of the group who had job were higher than those who had no job activity in the subgroup of 35 years or more age, below high school, height of 163cm or above, but there were no significant difference. 5. Rate of preterm delivery still showed better results in the group who had job than the group who had no job when adjusted for variables related, but there was no statistical significance. 6. Rate of low birth weight still showed better results with statistical significance in the group who had job than the group who had no job when adjusted for variables related. 7. Spontaneous abortion had occured less frequently in the group who had job than the group who had no job when adjusted for variables related. 8. Rate of preterm delivery and low birth weight were lower in the group of teacher, bank clerk, medical personnel, citizen servant than the group who had no job, but higher in the job of company employee, commerce. Spontaneous abortion was most frequent in group of commerce, and the group of teacher, company employee showed higher rate of abortion than the group who had no job.

熟地黃의 效能 중 補血作用에 대한 文獻的 硏究

鄭德震,徐榮培 대전대학교 한의학연구소 2001 혜화의학회지 Vol.9 No.2

1.《Graphical Materia Medica》 is first book that writes about Rehmanniae Radix Preparat. 《Shen nong's herbal》 is only written about Rehmanniae Radix. 2.After the 《Decoction Materia Medica》, orintal dortors use Rehmanniae Radix's effect is removing heat from the blood and Rehmanniae Radix's effect is enriching the blood. 3.Rehmanniae Radix Preparat is kinds of durgs for enriching the blood, because Rehmanniae Radix Preparat's effect do nourishing yin and supplementing blood. Therefore, Rehmanniae Radix Preparat is uesd simple recipe or Rehmanniae Radix Preparat is used with another herbs that shows so good effect of hematogenous functions at laboratory work. 4.Bone marrow is doing hematogenesis. That has relation to Rehmanniae Radix Preparat's effect is replenishing bone marrow, it's channel tropisms are liver·kidney channels. 5.Rehmanniae Radix Preparat's guide component is 5-HMF, but effective component has relation with hematogenesis is mannitol of saccharides. And we need more reserch about Rehmanniae Radix Preparat.

전문 실습장내의 작업환경소음으로 인한 PSIL 개선에 관한 연구

이종길,배영덕 안동대학교 환경연구소 2001 환경연구 Vol.1 No.-

This research is to investigate of PSIL improvement caused by the work environmental noise at the integrated mechanical laboratory of the technical high school. J technical high school was selected as an analytical place and the noise level was measured. To make a normal speech communication between teacher and student at the distance of 5ft, environmental noise level have to be attenuated about 10∼20dBA. To improve PSIL, barrier can be installed at the distance of 1.5m from the noise source and 1.2m above the ground.

노인틀니 보험급여를 위한 건강보험재정추계연구

권호근,김영남,정기호,송근배,박덕영 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.3

The purpose of this study is to estimate the National Health Insurance budget needed for the Korean elderly's denture service coverage. For more exact estimating the budget, denture need and demand were calculated by using 2000 National Oral Health Survey data. The results were summarized as follows ; 1. Over 65 years old, full denture and partial denture need per arch were each 8.5% and 16.8%. And over 70 years old, those were each 11.3% and 17.8%. 2. Over 65 years old, full denture and partial denture demand per arch were each 22.8% and 21.2%. And over 70 years old, those were each 27.%% and 21.1%. 3. Based on the denture need, the health insurance budget needed in the first operative year was about 955.4 billion won, over 65 years old and about 644.2 billion won, over 70 years old. 4. Based on the denture demand(wear), the health insurance budget needed in the first operative year was about 207.5 billion won, over 65 years old and was about 151.6 billion won, over 70 years old. If health insurance policy of elderly's denture service coverage is performed, actual denture wear rate is going to increase, and the budget needed is also increasing. Because current National Health Insurance budget status is poor, it is difficult to execute health insurance coverage for elderly's denture service. Therefore we suggest that health insurance coverage for preventive service is to be considered in order to reducing denture need in the long term view.

다시마 푸코이단추출물과 지질대사의 연관성

강금석,남천석,김인덕,권륜희,이동찬,허예영,하배진 신라대학교 자연과학연구소 2007 自然科學論文集 Vol.16 No.-

The effects of Laminaria japonica fucoidan extract (LJFE) on the biochemical parameters of lipid-related function were investigated in liver and serum of CCl_(4)-treated rats. LJFE of 100 mg/kg concentration was intraperitoneally administered into rats at dose of 1.5 ml/kg for 14 days. On the day 15, 3.3 ml/kg of CCl_(4) dissolved in olive oil (1:1) was injected 12 hours before anesthetization. We examined the lipid-related functions and enzyme activitys by measuring the levels of total cholesterol (TC), triglyceride (TG), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH) in serum. The results showed that CCl_(4) treatment increased the high values of TG, LDH and ALP decreased the low values of TC but LJFE pretreatment decreased the high values of TG, LDH and ALP to the low values, increased the TC. It was suggested that LJFE can be used as the potential candidate for the lipid-metabolism natural supplement.

스테비아 이용 딸기잼 제조 시 딸기 품종 (계통) 선발 및 가공 적성 검정

Young Deok Bae,Sang Un Kim,Jong Hyuk Kim,Dong Hyung Lim,Sun Yi Lee,Il Rae Rho 한국약용작물학회 2017 한국약용작물학술대회 발표집 Vol.2017 No.05

Background : Currently, obesity and adult diseases as a result of sugar intake have been a consistent problem in Korea. Natural sweeteners as sugar substitutes have many advantages over sugar as a small quantity. Therefore, this study was conducted to investigate possibility of industrialization as food additives by using the nature sweetness components of stevia (Stevia rebaudiana Bertoni). Method and Results : Stevia was cultivated in a plastic house. The leaves and stems were harvested at October. They were ground into fine powder using a mill, and were extracted by high temperature and pression extraction method. The extracts were evaporated under vacuum and lyophilized. Three strawberry cultivars of ‘Seolhyang’, ‘Maehyang’, and ‘F22-196’ were cultivated in a plastic house and were harvested from March to May. The fruits harvested were stored at 50℃ until processing. In order to test the processing suitability of stevia extract, the characteristics of the three strawberry varieties (line) were investigated. As a result, the ‘F22-196’ line, which was bred as a processing strawberry, generally contained more antioxidant materials and activity than those of ‘Maehyang’ and ‘Seolhyang’ varieties. Comparing the sugar contents which affects the quality of strawberry jam, the average sugar contents of ‘F22-196’ line was higher than 'Maehyang' and 'Seolhyang' varieties. In the preparation of strawberry jam using ‘F22-196’, strawberry jam was prepared by adding only sugar or stevia extract powder, which was 1/100 of the amount of the sugar in only sugar strawberry jam, to the sensory test. As a result, we identified that sugar jam and stevia jam added stevia extract showed 50 : 50 at the sensory test and stevia jam does not make a difference to the marketing jam at the point of view of general consumers. Conclusion : ‘F22-196’ line represented the best quality for strawberry jam in test caltivars. Stevia powder is judged to be used as a sweetener of sugar substitutes in the production of strawberry jam and processing food.

Review of the Application of Stevia as a Natural Food Additive and Selection of Suitable Strawberry Cultivar for Strawberry Jam

Young Deok Bae(배영덕),Sang Un Kim(김상언),Jong Hyuk Kim(김종혁),Dong Hyung Lim(임동현),Sun Yi Lee(이선이),Il Rae Rho(노일래) 한국약용작물학회 2017 한국약용작물학회 학술대회논문집 Vol.2017 No.1

Clinical Features of Polyarteritis Nodosa in Korea

Bae, Young Deok,Choi, Hyo Jin,Lee, Jung Chan,Park, Jeong Jin,Lee, Yun Jong,Lee, Eun Bong,Song, Yeong Wook The Korean Academy of Medical Sciences 2006 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.21 No.4

<P>Polyarteritis nodosa (PAN) is a systemic vasculitis characterized by multi-organ involvement with protean manifestations. We evaluated the clinical features of PAN in Korea. Twenty-seven patients were diagnosed as PAN at Seoul National University Hospital between January 1990 and July 2003. The male-to-female ratio was 1.7:1 and mean age at onset (±SD) was 47.4±20 yr. Their presenting features at diagnosis were similar to those reported previously, i.e., myalgia, muscle weakness or leg tenderness (70%), fever (52%), weight loss >4 kg (44%), skin rash (44%), peripheral edema (33%), abdominal pain (33%), and arthralgia/arthritis (30%). However, the prevalence of testicular pain or tenderness was higher (24%) than reported previously and only three (11.5%) had HBsAg positivity without liver enzyme elevation. Nine patients (33%) had a five-factor score (FFS) of 2. Fourteen patients (52%) responded to treatment, 2 patients relapsed and 4 died within 1 yr of diagnosis. During a median follow-up of 55.5 months, three of the four PAN-related deaths had an initial FFS of 2. The clinical features of PAN were not significantly different from those reported previously. However, testicular pain or tenderness was more frequent and patients with a high FFS tended to have a poorer prognosis.</P>