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희생이라는 가치는 여전히 유효한가? : 빅히스토리 관점에서 조망한 새라 코클리의 기포드 강좌 연구
최유진 ( Choi¸ Yoojin ) 한국조직신학회 2020 한국조직신학논총 Vol.61 No.-
Ⅰ. 서론 Ⅱ. 본론 Ⅲ. 결론 참고문헌 Sarah Coakley, English Anglican priest and systematic theologian, criticizes reductionary determinism and the ontological randomness of evolution, suggesting instead that the history of nature follows a Trinitarian God’s good purpose. Through collaboration with mathematician-evolutionary biologists, she explores how evolution proceeds from cooperation as well as selection and variation. In her Gifford lectures, she argues that the cooperation phenomena on a pre-human level seems to be a prerequisite stage for the intentional altruism and sacrifice of higher apes and on the human level. She also claims that through this evolution of cooperation, we can talk about God and divine purpose without avoiding the discourse of natural science. This paper engages in Coakley’s efforts. To this end, this paper first describes her lengthy investigation of the theme of ‘sacrifice’ and her theology as théologie totale as the backdrop of her Gifford lectures. Secondly, this paper summarizes her Gifford lectures, Sacrifice Regained: Evolution, Cooperation and God. The paper engages in a critical dialogue between Coakley and Martin Nowak (mathematician and evolutionary biologist) and Jean Porter(neo-Aristotelian-Thomistic philosopher) in order to investigate the core theme, ‘the restoration of evolution of cooperation and teleology’ more deeply. Finally, from a perspective of a ‘big history’ it reflects her Gifford lectures.
제어기 공용화를 위한 LED 헤드램프 제어용 플랫폼 통합제어기 개발
박충섭(Choongseob Park),박동서(Dongseo Park),이은정(Eunjung Lee),김대현(Daehyun Kim),손유진(Yoojin Son),최윤석(Yunsuk Choi4),박상현(Sanghyun Park),문주환(Juwhan Moon),노태선(Taesun Rho),강소정(Sojeong Kang),이동주(Dongju Lee),김영수(You 한국자동차공학회 2018 한국자동차공학회 부문종합 학술대회 Vol.2018 No.6
For the LED front lamp system, Universal Controller is gradually getting expanded in the world. For corresponding the technical trend and system optimization, we have approached in terms of vehicle level as well as LED load level. By understanding lamp system architecture and hardware functional distribution, we could make discrete LDMs into Universal LDM based on CAN communication. It enables us to control LED lamp very flexible and scalable with regardless of lamp variation depend on regional and specified option. Additionally, it is very compatible with future technologies such as pixel and matrix control in connection with autonomous driving.
Choi, Yoojin,Kim, Aeree,Kim, Jinkyoung,Lee, Jinhwan,Lee, Soo Yeon,Kim, Chungyeul 한국유방암학회 2017 Journal of breast cancer Vol.20 No.4
<P><B>Purpose</B></P><P>Breast cancer has a high prevalence in Korea. To achieve personalized therapy for breast cancer, long-term follow-up specimens are needed for next-generation sequencing (NGS) and multigene analysis. Formalin-fixed paraffin-embedded (FFPE) samples are easier to store than fresh frozen (FF) samples. The objective of this study was to optimize RNA extraction from FFPE blocks for NGS.</P><P><B>Methods</B></P><P>RNA quality from FF and FFPE tissues (n=5), expected RNA amount per unit area, the relationship between archiving time and quantity/quality of FFPE-extracted RNA (n=14), differences in quantitative real-time polymerase chain reaction (qRT-PCR) and NGS results, and comparisons of both techniques with tissue processing at different institutions (n=96) were determined in this study.</P><P><B>Results</B></P><P>The quality of RNA did not show any statistically significant difference between paired FF and FFPE specimens (<I>p</I>=0.49). Analysis of tumor cellularity gave an expected RNA amount of 33.25 ng/mm<SUP>2</SUP>. Archiving time affected RNA quality, showing a negative correlation with RNA integrity number and a positive correlation with threshold cycle. However, RNA from samples as old as 10 years showed a 100% success rate in qRT-PCR using short primers, showing that the effect of archiving time can be overcome by proper experiment design. NGS showed a higher success rate than qRT-PCR. Specimens from institution B (n=46), which were often stored in a refrigerator for more than 6 hours and fixed without slicing, showed lower success rates and worse results than specimens from the other institutes.</P><P><B>Conclusion</B></P><P>Archived FFPE tissues can be used to extract RNA for NGS if they are properly processed before fixation. The expected amount of RNA per unit size calculated in this study will be useful for other researchers.</P>
Choi, Yoojin,Park, Tae Jung,Lee, Doh C.,Lee, Sang Yup National Academy of Sciences 2018 Proceedings of the National Academy of Sciences Vol.115 No.23
<P>Nanomaterials (NMs) are mostly synthesized by chemical and physical methods, but biological synthesis is also receiving great attention. However, the mechanisms for biological producibility of NMs, crystalline versus amorphous, are not yet understood. Here we report biosynthesis of 60 different NMs by employing a recombinant Escherichia coli strain coexpressing metallothionein, a metal-binding protein, and phytochelatin synthase that synthesizes a metal-binding peptide phytochelatin. Both an in vivo method employing live cells and an in vitro method employing the cell extract are used to synthesize NMs. The periodic table is scanned to select 35 suitable elements, followed by biosynthesis of their NMs. Nine crystalline single-elements of Mn3O4, Fe3O4, Cu2O, Mo, Ag, In(OH)(3), SnO2, Te, and Au are synthesized, while the other 16 elements result in biosynthesis of amorphous NMs or no NM synthesis. Producibility and crystallinity of the NMs are analyzed using a Pourbaix diagram that predicts the stable chemical species of each element for NM biosynthesis by varying reduction potential and pH. Based on the analyses, the initial pH of reactions is changed from 6.5 to 7.5, resulting in biosynthesis of various crystalline NMs of those previously amorphous or notsynthesized ones. This strategy is extended to biosynthesize multi-element NMs including CoFe2O4, NiFe2O4, ZnMn2O4, ZnFe2O4, Ag2S, Ag2TeO3, Ag2WO4, Hg3TeO6, PbMoO4, PbWO4, and Pb-5(VO4)(3)OH NMs. The strategy described here allows biosynthesis of NMs with various properties, providing a platform for manufacturing various NMs in an environmentally friendly manner.</P>
한국 농장동물 수의사의 항생제 신중사용에 대한 인식과 실천
Yoojin Choi,Seola Joo,Sang-Won Lee,Hong-Jae Lee,Myung-Sun Chun 대한수의학회 2023 大韓獸醫學會誌 Vol.63 No.2
Antimicrobial (AM) resistance is a growing threat in human and veterinary medicine, spreading across species and perceived as One-Health issue. Prudent use of AM products is essential in mitigating this risk in both human and veterinary medicine. Farm veterinarians, responsible for prescribing appropriate AM and offering advice to farmers on their proper usage, are regarded as key players in the livestock industry. An online survey of farm veterinarians (n = 1,531) was conducted to assess their educational experience, beliefs, current status of prescription, practical behavior, and self-efficacy regarding the prudent use of antimicrobials (PUA). The data from 170 respondents were analyzed using descriptive statistics, regression and mediation analysis. Participants chose AM based on their experiences, academic resources, and peer veterinarians. Approximately 77% did not routinely conduct antibiotic-susceptibility-test. Most participants believed in the importance of PUA and the role of veterinarians to reduce AM resistance, but they reported a lack of awareness among farmers and insufficient national support interfere with their practical behavior with regard to PUA. Half of the participants had PUA-education, and 78.6% reported that education had a positive impact on their behavior with PUA. Self-efficacy partly mediates the relationship between belief and behavior for PUA, which accounted for 23.77% of the total effect that beliefs have on behavior for PUA. The findings of the study show that enhancing veterinarians’ abilities to practice and their self-efficacy through education tailored to the current status of farms can contribute to the reduction of AMs in the livestock sector.