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석유화학 플랜트용 프로세스 펌프의 국산화율 제고 방안에 관한 연구
조원배,문승재,유호선,Cho, Won-Bae,Moon, Seung-Jae,Yoo, Hoseon 한국플랜트학회 2009 플랜트 저널 Vol.5 No.3
In this paper, the present condition for localization of process pumps and the enhancement method of the localization ratio of process pumps for refinery and chemical plant market were studied. The market of plant industry in the world has grown rapidly since 2000. However, the profit of domestic plant EPC compaies cound not have been increased as much as the market scale because they procured most of equipment from overseas. To make remarkable profit of plant EPC companies in the petrochemical industry, localization of equipments is required. Suitable equipment for localization is process pump applied API 610 standard. An purchased amount of pumps from overseas by domestic plant EPC companies in the last two years were 230 billion won. If process pumps are localized then an profit of plant EPC project will increase.
Hypereosinophilic Syndrome Associated with the Onset of Rheumatoid Arthritis: A Case Report
( Jae-hee Park ),( Won-seok Lee ),( Seoung Ju Park ),( Wan-hee Yoo ) 대한류마티스학회 2017 대한류마티스학회지 Vol.24 No.3
Idiopathic hypereosinophilic syndrome (HES) is a disorder characterized by the sustained overproduction of eosinophils and multiple organ damage. Rheumatologic manifestations of HES are infrequent, but persistent eosinophilia is observed in approx.-imately 10% to 40% of patients with rheumatoid arthritis (RA). This finding may be a result of the RA itself and is often associated with active disease and the presence of extra-articular features. We describe the case of a 48-year-old man affected by HES who subsequently developed RA. Both HES and RA responded rapidly to the corticosteroid and methotrexate therapy. In this patient, the initiation of RA and HES was related, suggesting a common pathogenetic link between these two diseases. (J Rheum Dis 2017;24:165-168)
Yoo, Jae-Won,Lee, Hyun-Jung,Hong, Jae-Sang Korean Ocean Research & Development Institute and 2016 OCEAN SCIENCE JOURNAL Vol.51 No.3
We performed a time-series analysis of environmental variables and biological parameters to understand temporal variations in the macrobenthic community in the Chokchon macrotidal flats, Incheon, Korea. Bimonthly sampling of macrobenthos and sediments was conducted from May 1989 through November 2001. A decomposition method composed of seasonality, trends and cyclical variation was employed in this study. We focused on trends of the selected variables and assumed that those with positive or negative trends caused changes in biological parameters. Most variables showed strong seasonality (<TEX>${\geq}95%$</TEX> of the total variance). Significant positive trends (p < 0.0001) were observed in sea water temperature and sediment ignition loss. Macrobenthic biomass and species number also showed significant positive trends (p < 0.0001). Biomass indicated that the study area underwent eutrophication since the mid 1990s. A notable increase in species number occurred throughout the study period. The flattened temperature trend after 1994 and intensified eutrophication after the mid 1990s indicated that the species increase in the former period was in response to increasing temperature, while that in the latter period was caused by eutrophication. Although our study suggested an increasing trend in diversity, it is important to check for unexpected changes and establish monitoring programs to provide early warnings, especially in lower latitudes.
( Jae Yik Lee ),( Sang Joon Park ),( Jae Hyuk Lee ),( Mi Kyung Kwak ),( Hye Jeong Kim ),( Dong Won Byun ),( Kyo Il Suh ),( Myung Hi Yoo ),( Hyun Sook Kim ),( Hyeong Kyu Park ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1
Introduction: Several capillary changes detected by finger nailfold capillaroscopy have been shown to correlate with microvascular complications in type 1 diabetes. However, there are few reports on the relationship between nailfold capillary abnormalities and microvascular complications in type 2 diabetes (T2DM). Herein, we investigated whether nailfold capillary microscopic changes are associated with diabetic nephropathy in patients with T2DM. Methods: We conducted a cross-sectional study in patients with T2DM diagnosed within 20 years (duration of diabetes: 6.4±6.0 years). The nailfold capillaroscopy can visualize the capillary network in fingers and is a non-invasive test. The presence of morphological abnormalities, including avascular areas, giant capillaries, dilated, tortuous, or ramified capillaries, hemorrhages and capillary architectural derangements, in finger nailfold capillaroscopy image was assessed by a single rheumatology specialist. The severity of nailfold capillary change (0 : no change, 1 : capillary change/mm <33%, 2 : capillary change/mm between 33-66%, 3 : capillary change/mm >66%) was scored. Statistical analyses were performed using Pearson correlation or Spearman rank correlation as appropriate Results: A total of 63 patients with T2DM were enrolled. Both capillary architectural derangements and avascular areas in nailfold capillaroscopy showed significant correlations with albuminuria measured by spot urine or 24-hour urine collection after adjusting for sex, age, body mass index, duration of diabetes, hemoglobin, and HbA1C. Moreover, architectural derangements and avascular areas in nailfold capillaries were significantly associated with urinary albumin excretion rate in T2DM patients diagnosed within 10 years. Conclusions: These findings have shown that nailfold capillary abnormalities are independently associated with albuminuria in patients with T2DM of moderate duration, suggesting a role of capillary changes in the pathogenesis of diabetic nephropthy.
Fluorination of UO2 and CeO2 Under the Atmosphere of HF and H2
Yoo, Jae Hyung,Park, Jin Ho,Kim, Eung Ho,Kwon, Sang Woon,Hwang, Doo Seong,Cheong, Won Myung 한국공업화학회 2002 Journal of Industrial and Engineering Chemistry Vol.8 No.1
In this study, hydrofluorination of UO₂ and CeO₂ was carried out at 550℃ under the atmosphere of H₂ and HE Uranium dioxide was used as the main constituent of spent oxide fuel and CeO₂ used as a surrogate of transuranic oxides. Two hydrofluorination methods were presented: one is a direct hydrofluorination method in a molten fluoride salt and the other is that by gas solid reaction. In the former case, a fluoride mixture of 67% LiF-33% BeF₂ was used as carrier molten salt. It was thermodynamically confirmed that UO₂ was converted to UF₄ and CeO₂ to CeF₃. As results of the experiments, in the case of UO₂, fluorination took place in both systems. In the case of CeO₂, however, hydrofluorination in the molten fluoride salt occurred only slightly because of the extremely low solubility of HF and H₂ in the molten fluoride salt. Based on this result, when fluorinating minor actinide oxides in a spent oxide fuel, hydrofluorination by gas solid reaction was predicted to be far superior to that in molten fluoride salt.
Yoo, Hye Soo,Chang, Yun Sil,Kim, Jin Kyu,Ahn, So Yoon,Kim, Eun Sun,Sung, Dong Kyung,Jeon, Ga Won,Hwang, Jong Hee,Shim, Jae Won,Park, Won Soon Williams Wilkins Co. [etc.] 2013 Pediatric research Vol.73 No.6
<P>Intrauterine infection can exacerbate postnatal hyperoxic lung injury. We hypothesized that antenatal betamethasone treatment attenuates hyperoxic lung injury aggravated by intrauterine infection in neonatal rats.</P>
Yoo, Ki-Yeon,Kim, In Hye,Cho, Jeong-Hwi,Ahn, Ji Hyeon,Park, Joon Ha,Lee, Jae-Chul,Tae, Hyun-Jin,Kim, Dae Won,Kim, Jong-Dai,Hong, Seongkweon,Won, Moo-Ho,Kang, Il Jun Medknow PublicationsMedia Pvt Ltd 2016 Neural regeneration research Vol.11 No.2
<P>In this study, we tried to verify the neuroprotective effect of <I>Chrysanthemum indicum</I> Linne (CIL) extract, which has been used as a botanical drug in East Asia, against ischemic damage and to explore the underlying mechanism involving the anti-inflammatory approach. A gerbil was given CIL extract for 7 consecutive days followed by bilateral carotid artery occlusion to make a cerebral ischemia/reperfusion model. Then, we found that CIL extracts protected pyramidal neurons in the hippocampal CA1 region (CA1) from ischemic damage using neuronal nucleus immunohistochemistry and Fluoro-Jade B histofluorescence. Accordingly, interleukin-13 immunoreactivities in the CA1 pyramidal neurons of CIL-pretreated animals were maintained or increased after cerebral ischemia/reperfusion. These findings indicate that the pre-treatment of CIL can attenuate neuronal damage/death in the brain after cerebral ischemia/reperfusion <I>via</I> an anti-inflammatory approach.</P>
Yoo, Jae Il,Choi, Chi Won,Kim, Hwa Su,Yoo, Jung Sik,Jeong, Young Hee,Lee, Yeong Seon Korea Centers for Disease Control and Prevention 2012 Osong Public Health and Research Persptectives Vol.3 No.2
<P><B>Objectives</B></P><P><I>Candida glabrata</I> is one of the most common causes of <I>Candida</I> bloodstream infections worldwide. Some isolates of <I>C glabrata </I>may be intermediately resistant to azoles, with some strains developing resistance during therapy or prophylaxis with fluconazole. In this study, we used a proteomic approach to identify differentially expressed proteins between fluconazoleresistant and -susceptible strains.</P><P><B>Methods</B></P><P>Membrane and cellular proteins were extracted from fluconazolesusceptible and fluconazole-resistant <I>C glabrata </I>strains. Differentially expressed proteins were compared using two-dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis. Proteins with >1.5-fold difference in expression were identified by liquid chromatography tandem mass spectrometry (LC-MS/MS).</P><P><B>Results</B></P><P>A total of 65 proteins were differentially expressed in the cellular and membrane fractions. Among the 39 cellular proteins, 11 were upregulated and 28 were downregulated in fluconazole-resistant strains in comparison with fluconazole-susceptible strains. In the membrane fraction, a total of 26 proteins were found, of which 19 were upregulated and seven were downregulated. A total of 31 proteins were identified by LC-MS/MS that are involved in glycolysis, carbohydrate transport, energy transfer, and other metabolic pathways. Heat shock proteins were identified in various spots.</P><P><B>Conclusion</B></P><P>Heat shock and stress response proteins were upregulated in the membrane fraction of the fluconazole-resistant <I>C glabrata </I>strain. Compared with susceptible strains, fluconazole-resistant strains showed increased expression of membrane proteins and decreased expression of cellular proteins.</P>