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      • Dynamic Modeling and Parameter Identification of Magnetorheological Shock Absorber

        Yang Yonggang,Yu Peng,Zhu Shixing,Kong Xiangfen 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.9

        By dynamic analysis, the dynamic modeling of designed magnetorheological(MR) shock absorber with metering pin is established, and using the experimental data. The relation of kinematic viscosity and current, and shear stress and current are respectively identified, and the parameters of dynamic model are identified by the least square identification method. The experiment results show that the identified model has high accuracy, and can be used for the performance analysis and control system design of the shock absorber.

      • Land and Sea Engineering Geological Model and Division of the Laizhou Bay Coast, China

        ( Xiaoshuai Song ),( Yonggang Jia ),( Hongxian Shan ),( Xiaolei Liu ),( Yong Zhang ),( Xianghuai Kong ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

        In order to meet the development demands of Laizhou Bay Coastal Zone, there has carried out, including engineering survey, engineering geological drilling, in-situ test (standard penetration test), laboratory test, theoretical analysis and other research methods, in line with the layout of geo-spatial development and its geological environment characteristics. Through the analysis of the essential data, the stratigraphic structure, topography, geological structure and hydrogeological conditions of the study area were obtained. Based on the measured data of 24 engineering geological boreholes and the collected data of 202 boreholes, nine engineering geological layers were determined. And the types of rock and soil, the distribution of poor geological bodies and the engineering geology structural features have been understood. Based on that, the three-dimensional engineering geological model of Laizhou Bay coastal zone was established by using the software Mapgis K9. The image of the model objectively reflected the engineering stratigraphic structure and geological characteristics of the study area. Finally, the land area of the study area was divided into three major engineering geological areas and eight engineering geological sub-areas. Similarly, the sea area was divided into three major areas and six geological sub-areas. This work can provide local government with detailed and reliable basic data for development planning, provide scientific basis for coastal economic construction and sustainable development, and serve land and resources utilization, coastal zone development and management and planning.

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        Neonatal Immune State Is Influenced by Maternal Allergic Rhinitis and Associated With Regulatory T cells

        Lu Tan,Jing Ou,Zezhang Tao,Yonggang Kong,Yuxuan Zhang 대한천식알레르기학회 2017 Allergy, Asthma & Immunology Research Vol.9 No.2

        Purpose: Maternal influences contribute to the origin of allergic diseases, but the mechanisms are not clear. The current literature prompted the role of epigenetics in the development of allergic diseases. We sought to investigate the roles of regulatory T (Treg) cells and Forkhead box p3 (Foxp3) DNA methylation in the process of maternal transmission of allergic rhinitis (AR) susceptibility. Methods: BALB/c female mice (AR mother) were sensitized by intraperitoneal injection of Dermatophagoides pteronyssinus (Der p) 1 on day 1 and 7. Then they mated with normal male mice on day 8. From day 21 to 28, the female mice were intranasal challenged with Der p 1 continuously. The normal controls were given with normal saline in the same way. On postnatal day 3, Female mice and their offspring were sacrificed to detect their histopathology in nasal mucosae, cytokines in sera of mother and spleen homogenates of offspring, Treg cells count, Foxp3 mRNA expressions, and Foxp3 DNA methylation levels in spleens. Results: Compared with the normal controls, neonatal offspring of Der p 1-stimulated female mice (AR offspring) showed the elevation of interleukin (IL)-4 (P<0.01) and IL-17 (P<0.01), the submission of IL-10 (P<0.01) in spleen homogenates. Further, Treg cells count in AR offspring decreased remarkably compared with the normal offspring (P<0.01). Though the difference of Foxp3 DNA methylation level between AR offspring and normal control offspring was not obvious, correlation analysis demonstrated that there was significantly positive correlation between Foxp3 DNA methylation level of mother and that of offspring (r=0.803, P<0.01). Conclusions: Under the influence of Maternal AR, their neonatal offspring develop into T-helper type 2 (Th2) dominant immune state, which is closely associated with the recession of Treg cells. Foxp3 DNA methylation may be a mechanism responsible for that maternal effect but still need more studies to ensure.

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