Genome-wide investigation of a Korean synthetic breed, Woori-Heukdon using the Illumina PorcineSNP60K BeadChip

Yong‑Min Kim,Ha‑Seung Seong,Jung‑Jae Lee,Da‑Hye Son,Jin‑Su Kim,Soo‑Jin Sa,Young‑Sin Kim,Tae‑Jeong Choi,Kyu‑Ho Cho,Joon‑Ki Hong,Jung‑Woo Choi,Eun‑Seok Cho 한국유전학회 2020 Genes & Genomics Vol.42 No.12

Background: Woori-Heukdon (KWH) is a Korean synthetic pig breed generated using Chookjin-Duroc (KCD), Chookjin-Chamdon (KCC), and their crossbreds. Currently, there is a severe lack of studies investigating the Korean breed populations including wild boars (KWB) throughout the genome. Objective: This study was performed to investigate the genetic characteristics of Korean pig populations at the genome-wide level. Methods: Using the SNP dataset derived from genotyped and downloaded datasets using the Illumina PorcineSNP60K BeadChip, we compared the genomes of 532 individuals derived from 23 pig breeds to assess the genetic diversity, inbreeding coefficient, genetic differentiation, and population structure. Results: KWB showed the lowest average expected heterozygosity (HE = 0.1904), while KWH showed the highest genetic diversity (HE = 0.02859) among Korean populations. We verified that the genetic composition of KWH, showing USD of 74.8% and KCC of 25.2% in ADMIXTURE analysis. In population structure analyses, KCC was consistently shown to be separated from other pig populations. In addition, we observed gene flow from Western pigs to a part of Chinese populations. Conclusion: This study showed that Korean native pigs, KCC have genetic differences in comparison with Chinese and Western pigs; despite some historical records and recent genetic studies, we could not find any clear evidence that KCC was significantly influenced by Chinese or Western breeds in this study. We also verified the theoretical genomic composition of KWH at the molecular level in structure analyses. To our knowledge, this is the first genomic study to investigate the genomic characteristics of KWH and KCC.

우심방을 침범한 거대 비호지킨씨 림프종 1예

강상범,진승원,이은경,박용현,최용호,김용주,박준철,김재형,홍순조,최규보,권종범,원용순,박건,이은희 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

유량변동에 따른 소양강유역 수질의 통계학적 해석

최한규,백경원,최용묵,최진우 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.B

This research was conducted with the aim of efficiently managing large scale of rivers such like Songyang-river through predicting water quality change with analyzing the characteristics of the flowing in nutrients and pollutants. The main result will be used as basic data for effectively operating reservoirs through controling water quality and quantity. The relationship between quantity of flow and water quality was analyzed and pollution loading into the basin was estimated. Three areas of Soyang-river upstream and one area of Suip-cheon in Yanggu-gun were selected as research sites. Flow and water quality were measured simultaneously. The relation between quantity of discharge and pollution concentration and between quantity of discharge and pollution loading were analyzed by statistical method, respectively. We provided a rating curve through measuring quantity of discharge(collection quantity of discharge)and pollutograph and pollution loading curve through water quality data. Also, we analyzed the correlation between quantity of discharge per unit area and pollution loading per unit area in each basin. As resurt of this research, Buk-cheon spot revealed an excellent first grade water quality for the items including BOD5, DO, and SS. The correlation coefficient between Buk-cheon spot's quantity of discharge and pollution loading was 0.896~0.996, showing the validity of analysis applying correlation curve formula of quantity of discharge and pollution loading in the same spot. Also, pollution loading per unit area of the items including BOD5, COD, DO, SS, T-N, T-P increased as area of basins get increased following the sequence of Buk-cheon, Suip-cheon, Naelin-cheon spots.

일부 산업재해 환자들에서 외상후 스트레스장애

최경숙,임채기,최재욱,강성규,염용태 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.3

연구목적 : 우리나라에서 산업 재해로 신체적 손상을 입고 입원해 있는 일부 근로자들을 대상으로 PTSD 발병여부를 조사하고, 산업 재해와 관련된 위험 인자를 파악하여 산업재해 이후 근로자들이 겪게 될 신체적 건강문제 뿐만 아니라 정신적 건장 문제 회복에 도움을 주고자 하였다. 방 법 : 2000년 7월에서 2000년 9월 사이에 산업 재해로 인해 신체적인 부상을 입고 입원 중인 인천 소재 산재병원의 남성 입원환자 47명을 대상으로 PTSD 발병여부와 관련 인자를 연구하기 위하여 구조화된 설문 조사와 CAPS를 이용한 진단적 면담을 시행하였다. 결 과 : CAPS를 이용한 면접조사 결과 최종 연구 대상자 47명중 12명(25.5%)이 PTSD로 나타났으며, 모두 증상의 지속 기간이 3개월 이상인 만성 외상후 스트레스장애로 분류되었다. PTSD군 12명과 non-PTSD군 45명을 비교한 결과 BDI, STAI-I, STAI-II, IES 점수는 PTSD 군에서 유의하게 높게 나타났다. 또한 SCR-90-R의 세부항목 중 편집 사고를 나타내는 PAR 점수가 유일하게 두 군 사이에 유의한 차이를 보이지 않았고 그 외의 항목들은 PTSD 군에서 유의하게 높았다. 산재 관련 위험 인자의 비교에서 환자가 주관적으로 보고한 의식의 상실 경험만이 PTSD군에서 유의하게 높게 나타나 이전의 다른 연구자와 일치된 소견을 보였다. 결 론 : 이상의 결과는 산재 사고 이후에 PTSD가 발생하고, 증상이 장기간 지속되어 만성화를 겪을 가능성이 있다는 것을 보여준다. 위험 인자 중에서 사고 관련 위험 인자로 의식의 상실에 대한 주관적인 보고만이 관련성이 있는 것으로 나타났으나, 그 외의 다른 인자들은 관련서이 없는 것으로 나타났다. 그러나 여러 가지 연구의 제한점이 많으므로 연구 시점을 달리하고 많은 대상자를 포함한 후속 연구를 시행해야 산업재해와 PTSD에 대한 이해를 높일 수 있을 것으로 사료된다. Objectives : This study was conducted to assess the development of posttraumatic stress disorder(PTSD) after occupational physical injuries and the risk factors in occupational accident patients for PTSD. Methods : Forty-seven occupational accident patients with physical injuries were administered BDI. STAI I and II, SCL-90-R, IES and questionnaires for risk factors and Clinician-Administered PTSD Scale(CAPS). Results : 1) 12 patients(25%) were diagnosed as PTSD. 2) The BDI, STAI I and II and IES scores are significantly high(<0.05) in PTSD group than non-PTSD group. 3) The subscales of SCL-90-R, with an exception of PAR subscale, showed higher scores(<0.05) in PTSD group. 4) The loss of consciousness(LOC) was only significant risk factor in the occupational accident related factors(<0.05). Conclusion : The results of this study show the development of PTSD among occupational accident patients. The loss of consciousness(LOC) was the only significant risk factor for PTSD in occupational accident patients.

이옥소우라늄(VI)이온과 질소- 산소 주개원자를 가진 거대고리 리간드와의 착물 형성에 관한 연구

최규성,김정,김용복 慶南大學校 附設 基礎科學硏究所 1990 硏究論文集 Vol.2 No.-

수용액에서 디아자 크라운 에테르 계의 고리 원자 수가 15개에서 18개인 거대고리 리간드와 이옥소우라늄(VI) 이온 간의 착물 형성에 대한 안정도 상수를 전위차적정법으로 조사하였다. 착물의 안정도 상수는 NenOdienH₄ < NtnOdienH₄< Ntn(OH)OtnH₄< NtnOenH₄< NtnOtnH₄의 순이었으며, 이와같은 안정도 상수의 변화에는 리간드의 염기도와 주개 원자의 배열이 영향을 미치고 있었다. 한편, 모든 리간드는 이옥소우라늄(VI) 이온과 매우 안정한 착물을 형성하는 것으로 밝혀졌는데, NenOdienH₄와 NtnOdienH₄착물의 안정도 상수를 여러 온도에서 조사한 결과, 착물의 안정도에는 착물 형성 과정의 엔탈피 및 엔트로피 변화 모두가 기여하고 있었다. The complexation of 15 to membered diaza crown ethers with dioxouranium(Ⅵ) ion were studied by potentiometry in aqueous solutions. The order of stability constants were NenOdienH₄ < NtnOdienH₄< Ntn(OH)OtnH₄< NtnOenH₄< NtnOtnH₄. The basicity and the arrangement of donor atoms on the ligands were affected on the stabilities. And all ligands formed very stable complex with dioxouranium(Ⅵ) ion. The stability constants of NenOdienH₄and NtnOdienH₄complexes were measured at various temperatures. As the results, enthalpy and entropy change of the complexation were distributed on the complex stabilities.

통일, 그것은 정신적 통일이어야 한다

최용철,임규정 군산대학교 현대이념연구소 1997 現代理念硏究 Vol.12 No.-

現代地籍理論의 體系化 構想(Ⅱ)

崔龍奎 청주대학교 사회과학연구소 1991 한국사회과학연구 Vol.10 No.-

The government, regarding the problem of land as one of the most important policies, has made every effort for settling an ever-increasing serious problem of land. The theory of land registration and management is a science which surveys the present state of land, records the present state, manages the recorded content, and operates them, and the land registration and management is understood as the official register recording the informations of the land. The more the importance of land is stressed to the modern people, the more the academic studies is increased. The theory of land registration and management which has been developed on a working level until now shall be developed to an academic study according to a request of the times. Therefore, this study comprehends (1) The academic necessity and character of the land registration and management, (2) The subject and scope of study of the land registration and management, (3) The approach to the land registration and management, and this is the latter part of the systemized concrete of the modern theory of the land registration and management.

Poly-N-(N'-methylnitroso carbamoyl)-vinylamine의 합성

崔舜圭,朴유미,李龍均 東亞大學校 1982 東亞論叢 Vol.19 No.1

The intermediate, polyvinylamine was obtained through the reaction of N-vinylacetamide with 12N HCI for 48hrs. and poly-N-(N-methylcarbamoyl)-vinylamine was obtained through the reaction of polyvinylamine with methylisocyanate for 2hrs. A potential antitumor agent, poly-N-(N-methylnitrosocarbamoy)-vinylamine was synthesized by nitrososation of poly-N-(N-methylcarbamoyl)-vinylamine with sodium nitrite in glacial acetic acid. The structural proofs of these compounds were done by I.R.

역사 학습에서의 의사결정

최용규 韓國社會科敎育硏究會 1997 社會科敎育學硏究 Vol.- No.1

現代地籍理論의 體系化 構想

崔龍奎 청주대학교 사회과학연구소 1988 한국사회과학연구 Vol.7 No.-

Today the importance of the function of cadastre has deen newly recognized by the government, the society, the individual, and organization. The land planning by the government, The use of land for industries, and the individual's ownership and its administration hold much more weight in our economic actuality. Furthermore, as the land is the marginal land and is required for taking measures to the demesne of the increase of population and for rendering great services to the national welfare coming from the upraising level of income and the change of the view of value. The more the land is important, the more registry is needed, for the actuality of the land is accompanied with the theory of cadastre. The use of land ley human being who has developed the surface of the land has been to the solid times, and has been also diversified into the development of sea. But the cadastre system has not accepted it yet and has not given full answers to diverse demand because of poverty of theory. Today the advanced nations have much interests in the general cadastre system and the studies related to the cadastre on the ground of the importance of the cadastre. In the meantime, mainly, the practical theory and the surveying technique developed by the working- level staffs have been arrived at a regular level, but the theory of cadastre as an information sources to act up to the desire of the modern still. The systematization of the theory of cadastre is a problem of the modern cadastre, and this shall be a driving power to bloom the flower of the land culture in this land. Therefore, this treatise is written on the focus of interests in the systematization of the theory.