초정밀 나노 분급기 개발에 관한 연구

성백섭,윤길하,차용훈 한국공작기계학회 2003 한국공작기계학회 춘계학술대회논문집 Vol.2003 No.-

Nanotechnology is the creation and utilization of materials, devices, and systems through the control of matter on the nanometer-length scale, that is, at the level of atoms, molecules, and supramolecular structures. The essence of nanotechnology is the ability to work at these levels to generate larger structures with fundamentally new molecular organization. These nanostructures, made with building blocks understood from first principles, are the smallest human-made objects, and they exhibit novel physical, chemical, and biological properties and phenomena. The aim of nanotechnology is to learn to exploit these properties and efficiently manufacture and employ the structures. Control of matter on the nanoscale already plays an important role in scientific disciplines as diverse as physics, chemistry, materials science, biology, medicine, engineering, and computer simulation. This paper describes the superprecision nano separator to productive particle size of nano powder, this separator system is very important in the industrial area for other high technology parts.

인체 체액내 황색포도상구균의 증식과 철 획득 기전

신성희,이강길,이명희,양남웅,임용,김진호 대한감염학회 2000 감염 Vol.32 No.5

石炭石과 無煙炭에 의한 밀·스케일의 還元

黃龍吉,李成龍,朴載奉 동아대학교 공과대학 부설 한국자원개발연구소 1986 硏究報告 Vol.10 No.1

Some coked anthracite and Mill Scale pellet was packed in a tube furnace. And then, the heating samples was reacted with CO₂ gas made from wasting acid. The results of the experiment of reduction and gasification were as follows. 1) When waste acid was neutralized by some lime stone, vields of CO₂ gas was attained 80%. 2) The amount of CO gas producted at 1100℃ was 1.37times the amount of CO₂ gas made from wasting acid, and 1.5 times the amount at 1300℃. 3) During 5 houre for experiment the rate of reduction was 78% at 100℃ and 97.2% at 1300℃. 4) When Mill Scale pellet was reducted into CO gas, the value of activation energy was 3154.2 ㎈/g-㏖. The following can be resulted from what mentioned above: The neutralization of waste acid by lime stone can be a preventive of water pollution. And we can product not only fuel gas by the gasification of the anthracite reacting with CO₂ gas, but also sponge iron by the reduction of Mill Scale. The above four results can serve as a base source for the production of those materials.

SHY-DRAGER SYNDROME에 의한 신경인성 방광 1례

임재성,나용길,윤율로 최신의학사 1995 最新醫學 Vol.38 No.4

공황장애(Panic Disorder) 환자의 MMPI 및 Rorschach 반응특성 : On the Characteristics of the Responses of MMPI and Rorschach Test in Patients with Panic Disorder

민성길,이호영,김명선 大韓神經精神醫學會 1984 신경정신의학 Vol.23 No.4

As the diagnastic criteria of DSM-Ⅲ was newly established, a lot of studies have been conducted on the biological and psychological aspects of Panic Disorder, but studies using psychological tests are few. Chambless insists that the patients in this diagnostic criteria have hysterical cognitive style. Therefore, in this study, we attempted to examine the characteristics of MMPI and Rorschach of 13 Panic Disorder patients and whether these characteristics support the hysterical cognitive style. The results are as follows; a. The group mean profile of MMPI is Hs-D-Hy-Pt type (1-2-3-7 type) and the frequency of Hy type (3-type) has got the highest points. b. For Rorschach Test, the patients showed M〈ΣC and FC〈C+CF in EB, which is the major indicator of hysteria. These results suggest that our subjects of Panic Disorder patients showed typically hysterical feature.

뇌자도 측정을 위한 저잡음 Nb SQUID 센서의 설계 및 제작

이용호,권혁찬,김진목,이상길,임청무,박용기,박종철 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

We report on the design, fabrication and performances of a low-noise Nb SQUID sensor for neuromagnetic measurements. The main features of the developed sensor are i) large flux-to-voltage transfer, making the SQUID readout electronics simple, and ii) use of the integrated planar pickup coil to eliminate the environmental magnetic field noises. The magnetic field noise of the developed SQUID sensor is below 5 fT/√Hz at 100 Hz, which is low enough to be used in neuromagnetic measurements.

鋼內 介在物의 Br-化合物 形成에 關하여

黃龍吉,李相允,金營三,成章鉉 東亞大學校 大學院 1980 大學院論文集 Vol.4 No.2

The results obtained from the experiment to make a comparison between thermal characteristics and chemical reactions of 10% Br-Methanol treated oxides, and inclusions and oxides in 18Cr-8Ni stainless steel can be concluded as follows; 1. It has been shown that when MnO2, Cr2O3, Fe2O3 and SiO2 are heated, they all give exothermic characteristics in the temperature range about 200 to 300℃, but they tend to be heated up endothermically in the range 300 to 900℃, except for the fact that when the reaction 3MnO2=Mn3O4+O2 occurs at 600℃, peak showing endothermic reaction is observed. 2. Specimens made by mixing some of oxides such as MnO2, SiO2, Fe2O3 and Cr2O3 and uheir complex compunds and inclusins have all produced similar reactions which are characterized by showing an exothermic for temperatures of up to approximately 300℃ and an endothermic for the temperature range 300 to 900℃. However, it is noted that some oxides containing Mn give a sharp peak which represents endothermic reaction. 3. Below 100℃ the thermal analysis curves obtained from specimens made by reacting each complex compound with 10% Br-Methanol have been shown to be similar to these for specimens not rected with 10% Br-Methanol, showing endothermic heating for temperatures from about 150 to 200℃ endothermic heating for higher temperatures than 200℃. 4. The X-ray diffraction analysis has shown that oxides such as Mn3O4 and Cr2O3 are observed from the complex compound with a ratio MnO2: Cr2O3=1:1, whereas in the case of the compound with a ratio MnO2:Cr2O3=2:1 peak for Mn3O4 only is observable without any trace for Cr2O3 on the diffraction chart. Furthermore in the compound of Fe2O3 and Cr2O3 the peak for Cr2O3 has been determined, but no peak for Fe2O3 can be found. 5. The x-ray diffraction analysis has also presented that in inclusions in steel and complex oxides extracted by using 10% Br-Methanol the inclusions give peaks for Cr2O3 only, and peaks for Mn3O4 and Cr2O3 are obtainable. Based on this observation only when inclusions in steel are extacted by using 10% Br-Methanol amorphous structure is formed by Br, but crystalline oxides are thought to be unchanged to the amorphous.

모 제약회사 근로자들의 직업성 천식 유병률과 약제 분말 노출수준

오성수,최용휴,김은아,이영목,장재길,유장진,박승현,김태균,정수영,김규상,강성규 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

목적: 제약회사에서 직업상 천식의 유병 규모를 파악하고 작업공정에 대한 작업환경 측정을 통해 제약회사의 약제 분말에 대한 노출수준을 평가하고자 하였다. 방법: 제약회사에서 약제 분말에 노출되는 근로자를 대상으로 천식을 선별하기 위하여 설문조사 및 진찰, 혈액검사, 폐기능 검사 그리고 피부단자시험을 실시하였고, 각 부서별 공정에 따라서 총분진과 항생제 또는 효소제 분말에 대한 작업환경 측정을 실시하였다. 직업상 천식이 의심되는 근로자에 대하여 기관지과민성에 대한 검사(메타콜린을 이용한 비특이 기관지유발시험)와 약제 분말 기관지유발시험을 실시하여 확진하였다. 결과: 설문조사 및 진찰에서 작업 관련 천식 증상이 있는 근로자는 11명(34.4%)이었고, 약제 분말을 이용한 피부단자시험에서 1+ 이상 반응을 보인 근로자 10명(31.2%)이었다. 비특이 기관지유발시험 결과 8명(25.0%)이 양성(PC20 ≤16 mg/ml)이었다. 약제 분말 기관지유발시험을 통해 직업상 천식으로 확진된 근로자는 5명(15.6%)이었다. 작업환경 측정에서 원료를 충진하거나 투입하는 작업 그리고 정립작업에서 약제 분말에 대한 노출이 많았다. 결론: 제약회사에서 직업상 천식은 주로 제조공정 중 약제 분말에 노출된 근로자에서 발생하여, 증상 및 직업성 천식의 유병률이 높았다. 따라서 원료를 충진 또는 투입하는 작업과 정립작업 등 제조과적에서 약제 분말 노출을 줄이기 위한 세심한 주의가 필요하여, 약제 분말을 취급하는 근로자에 대해서는 천식 증상 조사뿐 아니라 정기적으로 피부단자시험, 비특이 기관지유발시험 등을 실시하여야 할 것이다. Objectives: After the investigation of one worker with occupational asthma, we surveyed the preva- lence of occupational asthma and the exposure level of pharmaceutical dust of 32 workers in a pharmaceutical company. Methods: Thirty-two of the 90 employees participated in the survey which consisted of questionnaire, blood sampling, spirometry and skin prick tests with 8 common allergens as well as 9 antibiotics and 2 enzymes. Various indices of the working environment were also measured. Subjects who had a symptom suggestive of work-related asthma or positive skin prick test were further investigated by PC20 methacholine. Nine subjects who had a PC20 result of 16 mg/ml or less (n=7) or had work-related symptoms and positive skin prick test (n=2) were referred to undergo a specific bronchial provocation test to phar- maceutical dust in an academic allergic disease center. Results: Eleven of 32 workers (34.4%) had a work-related symptom suggestive of occupational asthma. Ten (31.2%) showed positive skin prick test. 8 (25.0%) had a PC20 result of 16 mg/ml or less (indicative of significant bronchial hyperresponsiveness), and 5 (15.6%) had a positive result on the specific bronchial provocation test. Exposure levels of stuffing, input of raw materials and screening process were relatively high. Conclusions: This survey showed that pharmaceutical workers have an increased risk of occupational asthma. Although pharmaceutical factories maintain a relatively good working environment, careful control of respiratory tract exposures, especially during stuffing, input or raw materials and screening process, is important to prevent occupational asthma. Pharmaceutical workers need to undergo regular skin prick and methacholine bronchial provocation tests, as well as asthmatic symptom survey, to ensure the early detection and prevention of occupational asthma.

의약품중 잔류유기용매 시험법 확립에 관한 연구

고용석,강찬순,최보경,김혜수,홍정희,최명신,김상현,장성재,김길수 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

Headspace-GC(딘5-GC)를 이용하여 ICH 잔류웅매 가이드라인 class 1, 2에 속하는 28종의 잔류유기웅매 분석방법을 연군한 결과 SPB-5, BB-WAX column을 동시 이용하여 각각을 확인, 정량할 수 있었다.또한 염의 참가효과, 평형시간,평형온도가 headspace분석에 미치는 영향을 검토한 결과 평형 시간 30분,평형온도 85℃,Na₂SO₄Ig을 첨가하여 시험할 때 최적 부넉조건을 나타내었다. 회수율은 1,1-achloroethene(68.3%)를 제외하고 90.9 ~ 114.5%로 패체적으로 양호하였다. 따로 HS-GCJECD, DB-524 column을 이용하여 9종의 잔류유기용매에 대하여 각각의 검랸선을 작성하고 검출한계를 구하였다. 실제 의약품 원료 10종및 제제 5종에 적용시킨 결과 모두 불검출되었으며 본 시험법은 의약품중의 잔류유기용매 분석에 적용할 수 있는 방법이라고 판단된다. The headspace-fC/FID(HS -GC/FID) method was performed for test method developnlent of residu;31 organic solvents in pfrarmaceuticals. Using SPB-S and BB-WAXcolumn, 28 kinds of solvents iri ICH residual sof)·ents guidetine class 1, 2 couBd be individuallt-identified and quantitated. The foIBowing residoal soIYents were not detected by the headspaceinjection condition : N,N-Cmethylacetamide, N,N-dimeth)rlformamide, ethyfeneglycol, formamide,2-methoryethanot, N-rnethylpyrrolidone, suBforane. The effects of the addition of salts,equilibration time, and equilibration temperature on headspace analt·sis were invesugated. Theoptimum conditions weiFe obtained with addtion of Ifa2s04 19 as a salt, simultaneously. thetime and temperature of equitibration were 30min and 8i'f, respectivety. The recovery havefound between 90.9 and 114.5% except 1,1-dichloroethene(fi8.3%). Using DB-624 column &HS-GC/:ECD method, 9 kinds of residual solvents could be individually identified andfuantitated. This HS-GC method can be applied to test the residua3 organic solvent in thepharmaceuticals.

독어 강변화 동사와 영어 불규칙 동사의 어간 모음에 관한 역사적 고찰

김길룡,임정성 慶南大學校 人文科學硏究所 1995 人文論叢 Vol.7 No.-