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- 저자 : Yinghua Pan (검색결과 3 건)
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Limin Liang,Yinghua Pan,DanchunWu,Yongli Pang,Yuanyuan Xie,Hengying Fang 한국간호과학회 2019 Asian Nursing Research Vol.13 No.2
Purpose: The purpose of this study is to investigate the impact of transitional care by a nurse-led multidisciplinary team (MDT) on clinical outcomes and quality of life of patients with ankylosing spondylitis. Methods: A randomized control study design was used. Subjects were allocated randomly to an experimental group and a control group. The experimental group received intensive transitional care by a nurse-led MDT, whereas the control group received routine nursing care. Disease activity, spinal mobility, comprehensive function, health service utilization, and quality of life were assessed at the baseline and at six months with the Bath Ankylosing Spondylitis Metrology Index, the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), the Bath Ankylosing Spondylitis Functional Index (BASFI), a health service utilization questionnaire and version 2 of the Short Form-36 health survey. Results: Compared with the baseline, the BASDAI, BASFI, emergency visits, hospitalizations, hospitalization days, and bodily pain, vitality, mental health, total score, and average score of version 2 of the Short Form-36 health survey were improved in the experimental group (p < .05), whereas only bodily pain, vitality, and role-emotional were improved in the control group (p < .05). At six months, the experimental group exhibited significantly more improvement on the BASDAI, BASFI, hospitalizations, all domains except Role-physical as well as total score and average score (p < .05) compared with the control group. Conclusion: A MDT-based nurse-led transitional care improves clinical outcomes and quality of life of patients with ankylosing spondylitis. Future research should be carried out on modes of follow-up and family support.
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Jiaxing Shen,Zihao Pan,Ping Xu,Yinghua Yu 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.7
The thermal performance of a steel-basalt fiber polymer concrete machine tool joint surface has a key influence on a machine tool. Based on virtual material theory, the equivalent thermal model was established and the thermal performance parameters of virtual materials were deduced by theoretical calculation. The calculation method of actual contact area ratio of steel - basalt fiber polymer concrete joint surface was established based on discrete principle and its accuracy was verified. To determine the influence of preload pressure on the actual contact area ratio, a prediction model was established. The thermal conductivity of the material was measured by the quasi-steady state method. A new systematic simulation analysis method that synthesizes virtual material theory and finite element simulation analysis was proposed, and its accuracy was verified. The results show that the relative error is only 5.01 %, which proves the method’s effectiveness.
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Min Cao,Youjun Feng,Changjun Wang,Feng Zheng,Ming Li,Hui Liao,Yinghua Mao,Xiuzhen Pan,Jing Wang,Dan Hu,Fuquan Hu,Jiaqi Tang 한국미생물학회 2011 The journal of microbiology Vol.49 No.6
Quorum sensing is a widespread chemical communication in response to fluctuation of bacterial population density, and has been implicated into bacterial biofilm formation and regulation of expression of virulence factors. The luxS gene product, S-ribosylhomocysteinase, catalizes the last committed step in biosynthetic pathway of autoinducer 2 (AI-2), a signaling molecule for inter-species quorum sensing. We found a luxS homologue in 05ZYH33, an epidemic strain of Streptococcus suis serotype 2 (SS2) in China. A luxS null mutant (ΔluxS) of 05ZYH33 strain was obtained using an approach of homologous recombination. LuxS was determined to be required for AI-2 production in 05ZYH33 strain of S. suis 2. Inactivation of luxS gene led to a wide range of phenotypic changes including thinner capsular walls, increased tolerance to H_2O_2, reduced adherence capacity to epithelial cells, etc. In particular, loss of LuxS impaired dramatically its full virulence of SS2 in experimental model of piglets, and functional complementation restored it nearly to the level of parent strain. Genome-wide transcriptome analyses suggested that some known virulence factors such as CPS are down-regulated in the ΔluxS mutant, which might in part explain virulence attenuation by luxS deletion. Similarly, 29 of 71 genes with different expression level were proposed to be targets candidate regulated by LuxS/AI-2-dependent quorum sensing.
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