Epidemiology of Esophageal Cancer in Yanting - Regional Report of a National Screening Programme in China

Wang, Xiao,Fan, Jin-Chuan,Wang, An-Rong,Leng, Yue,Li, Jun,Bao, Yu,Wang, Ying,Yang, Qing-Feng,Ren, Yu Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4

Background and Objectives: Yanting in Sichuan Province is one of the highest risk areas of esophageal cancer (EC) in the world. We here summarize the epidemiology of EC in Yanting using data from the national screening programme during 2006-2011. Methods: Random cluster sampling was used to select a proportion of natural villages from six towns in Yanting, and residents aged 40-69 years old were invited for screening. Participants were screened using endoscopy with iodine staining and then confirmed by histological examinations. Results: The overall detection rates of low-grade hyperplasia (LH), moderate hyperplasia (MH), high-grade hyperplasia (HH), carcinoma in situ (CIS), intramucosal carcinoma (IC) and invasive carcinoma (INC) were 5.33%, 1.28%, 0.68%, 0.15%, 0.06% and 0.29%, respectively. The detection rates of LH, MH, HH and INC increased with age, reaching the peak among those aged 60-65 years, and the prevalences of LH and MH were higher among men than among women. In addition, the detection rates of hyperplasia were much higher in mountainous than in hilly areas. Conclusions: Among the high risk population, there are a great number of people with early-stage EC or precancerous conditions who do not have presenting symptoms. In particular, the elderly, men, or those living in mountainous areas are the most vulnerable population. It is therefore important to reinforce health education and screening services among such high risk populations.

Pay attention to food health

Wang Yue 한국콘텐츠학회 2020 ICCC International Digital Design Invitation Exhib Vol.2020 No.11

Methods for distinguishing Mott transitions from Anderson transitions

Wang, Yue,Kang, Kyung Mun,Kim, Minjae,Yoo, Hyang Keun,Park, Hyung Ho Inderscience Enterprises Ltd. 2018 International Journal of Nanotechnology Vol.15 No.6

Implementing a Consistency Checker for Uncertain or Incomplete Temporal System

Yue Wang,Jixin Ma,Brian Knight 보안공학연구지원센터 2013 International Journal of Hybrid Information Techno Vol.6 No.6

Anticancer activity and potential mechanisms of 1C, a ginseng saponin derivative, on prostate cancer cells

Wang, Xu De,Su, Guang Yue,Zhao, Chen,Qu, Fan Zhi,Wang, Peng,Zhao, Yu Qing The Korean Society of Ginseng 2018 Journal of Ginseng Research Vol.42 No.2

Background: AD-2 (20(R)-dammarane-3b, 12b, 20, 25-tetrol; 25-OH-PPD) is a ginsenoside and isolated from Panax ginseng, showing anticancer activity against extensive human cancer cell lines. In this study, effects and mechanisms of 1C ((20R)-3b-O-(L-alanyl)-dammarane-12b, 20, 25-triol), a modified version of AD-2, were evaluated for its development as a novel anticancer drug. Methods: MTT assay was performed to evaluate cell cytotoxic activity. Cell cycle and levels of reactive oxygen species (ROS) were determined using flow cytometry analysis. Western blotting was employed to analyze signaling pathways. Results: 1C concentration-dependently reduces prostate cancer cell viability without affecting normal human gastric epithelial cell line-1 viability. In LNCaP prostate cancer cells, 1C triggered apoptosis via Bcl-2 family-mediated mitochondria pathway, downregulated expression of mouse double minute 2, upregulated expression of p53 and stimulated ROS production. ROS scavenger, N-acetylcysteine, can attenuate 1C-induced apoptosis. 1C also inhibited the proliferation of LNCaP cells through inhibition on $Wnt/{\beta}-catenin$ signaling pathway. Conclusion: 1C shows obvious anticancer activity based on inducing cell apoptosis by Bcl-2 family-mediated mitochondria pathway and ROS production, inhibiting $Wnt/{\beta}-catenin$ signaling pathway. These findings demonstrate that 1C may provide leads as a potential agent for cancer therapy.

Bone Marrow Adiposity, Bone Mineral Density and Wnt/β-catenin Pathway Inhibitors Levels in Hemodialysis Patients

Yue-Pei Wang,Nada Khelifi,Cyrille de Halleux,Roth-Visal Ung,France Samson,Claudia Gagnon,Fabrice Mac-Way 대한골대사학회 2022 대한골대사학회지 Vol.29 No.2

Background: Marrow adipose tissue (MAT) is known to accumulate in patients with chronic kidney disease. This pilot study aimed to evaluate bone mineral density (BMD), MAT, visceral adipose tissue (VAT), and subcutaneous adipose tissue (SAT) using computed tomography (CT) scans and to explore correlations between bone parameters, circulating Wnt/β-catenin pathway inhibitor levels, and adipose tissue parameters. Methods: Single-center cross-sectional pilot study conducted in hemodialysis patients at the Centre Universitaire de Québec, Hôtel-Dieu de Québec hospital, Canada. CT-scan slices were acquired at the levels of the hip, L3 vertebra, and tibia. Volumetric and areal BMD, tibia cortical thickness, VAT and SAT area, and fat marrow index (FMI) were analyzed using the Mindways QCT Pro software. Blood levels of sclerostin, dickkopf-related protein 1 (DKK1), fibroblast growth factor 23, and α-Klotho were assessed. Spearman’s rho test was used to evaluate correlations. Results: Fifteen hemodialysis patients (median age, 75 [66–82] years; 80% male; dialysis vintage, 39.3 [27.4–71.0] months) were included. While inverse correlations were obtained between L3 FMI and BMD, positive correlations were found between proximal tibial FMI and vertebral and tibial BMD, as well as with tibial (proximal and distal) cortical thickness. VAT had a positive correlation with α-Klotho levels, whereas L3 FMI had a negative correlation with DKK1 levels. Conclusions: CT-scan allows simultaneous evaluation of bone and marrow adiposity in dialysis patients. Correlations between MAT and BMD vary depending on the bone site evaluated. DKK1 and α-Klotho levels correlate with adipose tissue accumulation in dialysis patients.

Research on Phytotoxicity of Natural Colloids

Yue Wang,Xiangang Hu 대한환경공학회 2019 대한환경공학회 학술발표논문집 Vol.2019 No.-

Low temperature method to passivate oxygen vacancies in un-doped ZnO films using atomic layer deposition

Wang, Yue,Kang, Kyung-Mun,Kim, Minjae,Park, Hyung-Ho Elsevier 2018 THIN SOLID FILMS - Vol.660 No.-

<P><B>Abstract</B></P> <P>Owing to oxygen vacancies, the as-prepared ZnO normally shows n-type semiconducting characteristic. This has restricted the preparation of high-quality p-type ZnO and the application of ZnO optoelectronic devices. Therefore, we studied a method of using H<SUB>2</SUB>O<SUB>2</SUB> as an oxygen source to passivate oxygen vacancies (V<SUB>o</SUB>) in ZnO films via atomic layer deposition (ALD). The temperature range for the self-limited growth of crystalline ZnO thin films by ALD using diethylzinc and H<SUB>2</SUB>O<SUB>2</SUB> was found to be in the range of 80 to 150 °C. Our results show that the use of H<SUB>2</SUB>O<SUB>2</SUB> as an oxygen source can provide an O-rich condition (instead of H<SUB>2</SUB>O) for the growth of ZnO film, with a total preferential (002) orientation of the growth plane and decreased grain size. Further, the O-rich growth environment can suppress the formation of V<SUB>o</SUB> and zinc interstitials and decrease the carrier concentration in ZnO (from 2.525 × 10<SUP>19</SUP> cm<SUP>−3</SUP> to 1.695 × 10<SUP>12</SUP> cm<SUP>−3</SUP>). This can lead to an increase in the film resistivity from 1.717 × 10<SUP>−2</SUP> Ω·cm for a ZnO film prepared using H<SUB>2</SUB>O to 1.348 × 10<SUP>4</SUP> Ω·cm for a ZnO film prepared using H<SUB>2</SUB>O<SUB>2</SUB>. Thus, H<SUB>2</SUB>O<SUB>2</SUB> could be used to passivate V<SUB>o</SUB> in ZnO at a low temperature, and it could be beneficial for the preparation of p-type ZnO films.</P> <P><B>Highlights</B></P> <P> <UL> <LI> H<SUB>2</SUB>O<SUB>2</SUB> was proved to provide more oxygen than H<SUB>2</SUB>O for ALD growth of ZnO film. </LI> <LI> The oxygen-rich condition of H<SUB>2</SUB>O<SUB>2</SUB> can passivate the oxygen vacancy in ZnO film. </LI> <LI> Vacancy decrease leads to carrier concentration decrease and resistivity increase. </LI> <LI> H<SUB>2</SUB>O<SUB>2</SUB> passivates oxygen vacancy efficiently at low temperature than high temperature. </LI> </UL> </P>

Facile Synthesis and Properties of Aqueous CdTe Quantum Dots for High-Sensitive Copper (II) Ion Detection

Yue Zheng,Hengshan Tang,Xiaoyu Wang,Ya Di,Kunling Lu,Jidong Wang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.12

The synthesis of aqueous MPA-capped CdTe quantum dots (QDs) via a facile one-pot route was developed. The particle size, optical properties and crystal structure of the as-synthesis QDs were investigated by transmission electron microscopy (TEM), Fourier transform infrared (FTIR), UV-vis absorption and photoluminescence (PL) spectra, respectively. Meanwhile, the effect of reaction conditions, including reaction time, pH and the quantity of sodium citrate (SC) on the growth of CdTe QDs were discussed. Then, the obtained CdTe QDs were successfully used for the detection of trace Cu2+ with high sensitivity and excellent selectivity. The fluorescence intensity of CdTe QDs with Cu2+ concentration showed a linear relationship in the range from 1 x 10 -7 mol/L to 1 x 10 -6 mol/L. The correlation coefficient (R) is 0.9980 and limit of detection (LOD) is 1.0 x 10 -8 mol/L. Moreover, the concentration of Cu2+ in tap water samples was determined based on this sensing system and the recovery test was satisfactory.

A native Trichoderma harzianum strain Th62 displays antagonistic activities against phytopathogenic fungi and promotes the growth of Celosia cristata

Yue-Feng Wang,Xue-Yue Hou,Chuan-Ying Jiang,Tong-Tong Zhai,Rui Miao,Jun-Jie Deng,Zhi-Hong Yao,Rongshu Zhang 한국원예학회 2021 Horticulture, Environment, and Biotechnology Vol.62 No.2

Trichoderma spp. are widely applied, eco-friendly mycofungicides and plant growth promoters. Native Trichoderma strainsare likely to have more productive, stable biocontrol and biofertilizer activities since they are well adapted to the local environment. In this study, we isolated a native Trichoderma strain ‘Th62’ from the rhizosphere soil of wild Chelidonium majusplants in Harbin, China (126.6341°E, 45.7242°N). The isolated Trichoderma strain was identifi ed as a T. harzianum strainvia morphological observation and molecular methods based on the rDNA internal transcribed spacer region and elongationfactor-1α gene sequences. Signifi cant antagonistic activities of Th62 against fi ve soil-borne fungal phytopathogens,Fusarium oxysporum , Sclerotinia sclerotiorum , Alternaria alternata , Cytospora chrysosperma, and Rhizoctonia solani ,were confi rmed by dual-culture assays. Furthermore, the crude fermentation products of Th62 also displayed antifungalactivities against these fi ve pathogens. To evaluate the function of Th62 as a biofertilizer, we subsequently applied Th62on cockscomb ( Celosia cristata L), a plant species with both ornamental and medicinal values, by inoculation with Th62conidia at diff erent concentrations, 1 × 10 10 cfu mL −1 , 1 × 10 11 cfu mL −1 , and 1 × 10 12 cfu mL −1 . The benefi cial eff ects ofTh62 were evaluated by measuring the growth and photosynthetic traits of the inoculated cockscomb plants, and the resultsdemonstrated that Th62 signifi cantly improved the photosynthetic effi ciency, photosynthetic capacity, and the adaptabilityto intense light of the inoculated cockscomb plants compared to the controls. Consistently, Th62 inoculation signifi cantlyimproved the growth and fl ower yield of cockscomb. We presented a positive case of isolating and applying native microbialresources on local plantation practices.