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- 저자 : Xiaoqiang Luo (검색결과 4 건)
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Effects of Starvation on Lipid Metabolism and Gluconeogenesis in Yak
Yu, Xiaoqiang,Peng, Quanhui,Luo, Xiaolin,An, Tianwu,Guan, Jiuqiang,Wang, Zhisheng Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.11
This research was conducted to investigate the physiological consequences of undernourished yak. Twelve Maiwa yak ($110.3{\pm}5.85kg$) were randomly divided into two groups (baseline and starvation group). The yak of baseline group were slaughtered at day 0, while the other group of yak were kept in shed without feed but allowed free access to water, salt and free movement for 9 days. Blood samples of the starvation group were collected on day 0, 1, 2, 3, 5, 7, 9 and the starved yak were slaughtered after the final blood sample collection. The liver and muscle glycogen of the starvation group decreased (p<0.01), and the lipid content also decreased while the content of moisture and ash increased (p<0.05) both in Longissimus dorsi and liver compared with the baseline group. The plasma insulin and glucose of the starved yak decreased at first and then kept stable but at a relatively lower level during the following days (p<0.01). On the contrary, the non-esterified fatty acids was increased (p<0.01). Beyond our expectation, the ketone bodies of ${\beta}$-hydroxybutyric acid and acetoacetic acid decreased with prolonged starvation (p<0.01). Furthermore, the mRNA expression of lipogenetic enzyme fatty acid synthase and lipoprotein lipase in subcutaneous adipose tissue of starved yak were down-regulated (p<0.01), whereas the mRNA expression of lipolytic enzyme carnitine palmitoyltransferase-1 and hormone sensitive lipase were up-regulated (p<0.01) after 9 days of starvation. The phosphoenolpyruvate carboxykinase and pyruvate carboxylase, responsible for hepatic gluconeogenesis were up-regulated (p<0.01). It was concluded that yak derive energy by gluconeogenesis promotion and fat storage mobilization during starvation but without ketone body accumulation in the plasma.
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Lee, Dayoung,Jeong, Keunsoo,Luo, Xiao,Kim, Gayoung,Yang, Youjun,Chen, Xiaoqiang,Kim, Sehoon,Yoon, Juyoung The Royal Society of Chemistry 2018 Journal of Materials Chemistry B Vol.6 No.17
<P>Two new cyanine-based fluorescent probes 1 and 2 have been developed. Probe 1 bears two cyanine units in a single molecule, and probe 2 contains a bis(trifluoromethyl)benzenethiol moiety. Both are non-fluorescent. The addition of intracellular glutathione (GSH) significantly enhanced the NIR fluorescence of the two probes. Both probes were used to image varying amounts of GSH in living cells. In tumor bearing mice, the <I>in vivo</I> fluorescence intensity of both probes was higher in tumors, where GSH is overexpressed, than in normal tissues. These results suggest that these new fluorogenic probes have potential for GSH-targeting diagnostic imaging.</P>
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Efficient Multicast Routing on BCube-Based Data Centers
( Junjie Xie ),( Deke Guo ),( Jia Xu ),( Lailong Luo ),( Xiaoqiang Teng ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.12
Multicast group communication has many advantages in data centers and thus is widely used by many applications. It can efficiently reduce the network traffic and improve the application throughput. For the multicast application in data centers, an essential problem is how to find a minimal multicast tree, which has been proved to be NP-hard. In this paper, we propose an approximation tree-building method for the minimal multicast problem, named HD(Hamming Distance)-based multicast tree. Consider that many new network structures have been proposed for data centers. We choose three representative ones, including BCube, FBFLY, and HyperX, whose topological structures can be regarded as the generalized hypercube. Given a multicast group in BCube, the HD-based method can jointly schedule the path from each of receiver to the only sender among multiple disjoint paths; hence, it can quickly construct an efficient multicast tree with the low cost. The experimental results demonstrate that our method consumes less time to construct an efficient multicast tree, while considerably reduces the cost of the multicast tree compared to the representative methods. Our approach for BCube can also be adapted to other generalized hypercube network structures for data centers after minimal modifications.
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Yali Gong,Xiaodong Shen,Guangtao Huang,Cheng Zhang,Xiaoqiang Luo,Supeng Yin,Jing Wang,Fuquan Hu,Yizhi Peng,Ming Li 한국미생물학회 2016 The journal of microbiology Vol.54 No.8
Acinetobacter baumannii is an important opportunistic pathogen that causes severe nosocomial infections, especially in intensive care units (ICUs). Over the past decades, an everincreasing number of hospital outbreaks caused by A. baumannii have been reported worldwide. However, little attention has been directed toward the relationship between A. baumannii isolates from the ward environment and patients in the burn ICU. In this study, 88 A. baumannii isolates (26 from the ward environment and 62 from patients) were collected from the burn ICU of the Southwest Hospital in Chongqing, China, from July through December 2013. Antimicrobial susceptibility testing results showed that drug resistance was more severe in isolates from patients than from the ward environment, with all of the patient isolates being fully resistant to 10 out of 19 antimicrobials tested. Isolations from both the ward environment and patients possessed the β-lactamase genes blaOXA-51, blaOXA-23, blaAmpC, blaVIM, and blaPER. Using pulsed-field gel electrophoresis (PFGE) and multi-locus sequence typing (MLST), these isolates could be clustered into 4 major PFGE types and 4 main sequence types (ST368, ST369, ST195, and ST191) among which, ST368 was the dominant genotype. Epidemiologic and molecular typing data also revealed that a small-scale outbreak of A. baumannii infection was underway in the burn ICU of our hospital during the sampling period. These results suggest that dissemination of β-lactamase genes in the burn ICU might be closely associated with the high-level resistance of A. baumannii, and the ICU environment places these patients at a high risk for nosocomial infection. Cross-contamination should be an important concern in clinical activities to reduce hospital acquired infections caused by A. baumannii.
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