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Xavier PHILIPPE 한국공법학회 2018 公法硏究 Vol.47 No.1
La procédure administrative contentieuse française a fait l’objet de profondes réformes à la fin des années 1990 et le début des années 2000. Sous l’impulsion conjuguée du juge constitutionnel, du législateur et du juge administratif lui-même, la procédure administrative contentieuse française a semblé renforcer le droit à une procédure régulière équitable (due process of law). Le code de justice administrative a ainsi consacré nombre de principes qui avaient été dégagés par le juge mais qui furent consacrés législativement. Ce libéralisme dans la protection de la procédure équitable en matière contentieuse administrative a cependant ralenti sa progression depuis le milieu des années 2010. Le législateur et le pouvoir réglementaire ont multiplié les barrières destinées à discipliner les recours et à rationaliser la procédure et à permettre les réductions des délais de jugement. La procédure administrative contentieuse a ainsi davantage protégé l’efficacité au détriment de l’équité.
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( Philippe Rodon ),( Brigitte Pegourie ),( Laurent Garderet ),( Philippe Casassus ),( Olivier Decaux ),( Murielle Roussel ),( Carine Chaleteix ),( Bruno Royer ),( Mourad Tiab ),( Xavier Leleu ),( Clai 대한내과학회 2014 대한내과학회 추계학술발표논문집 Vol.2014 No.1
Background: Although infection is a major complication of multiple myeloma (MM), there are few data on its incidence, presentation and outcome. We reviewed severe infections occurring in the IFM 2009 01 protocol. Methods: The IFM 2009 01 protocol evaluated a combination of bendamustine, bortezomib and dexamethasone (BVD) in the treatment of elderly patients (65 years or more) with a relapsed or refractory (RR) MM (Rodon P. et al, Blood 2013;122:1971A). Patients did not receive any prophylactic antibiotics. All adverse events were collected and graded prospectively. We report here an analysis of the episodes of severe infection (grade 3 or more). Results: Seventy-three patients were included. The median age was 75.8 years (range 66-86). Twenty episodes of grade 3 or more infection occurred in 17 patients (23.2%): lung and respiratory tract infection 13 episodes, bloodstream infection 6 episodes and pyelonephritis 1 episode, respectively. Fourteen episodes were diagnosed in the early phase of therapy (within the 4 fi rst BVD cycles). Only 1 severe infection underwent during a chemotherapy-induced neutropenic phase (absolute neutrophil count < 1000/mm3). fifteen episodes occurred among 34 patients older than 75 years versus 5 episodes in 39 younger patients (p=0.0028). Sepsis was responsible of death in 4 of these 17 patients (23.5%), all occurring in the early phase. Conclusions: Infection was a major severe adverse event in elderly patients treated for RRMM in the IFM 2009 01 protocol, occurring in approximately one quarter of the patients. Its incidence was signifi cantly higher in patients older than 75 years. Severe episodes of infection mainly occurred in the early phase of treatment. Mortality rate was high. These fi ndings suggest that a systematic prophylactic use of antibiotics may be needed in this population of patients.
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Anne-Cécile Pizzoferrato,Arnaud Fauconnier,Xavier Fritel,Georges Bader,Philippe Dompeyre 대한배뇨장애요실금학회 2017 International Neurourology Journal Vol.21 No.2
Purpose: Maintaining urinary continence at stress requires a competent urethral sphincter and good suburethral support. Sphincter competence is estimated by measuring the maximal urethral closure pressure at rest. We aimed to study the value of a new urodynamic measure, the urethral closure pressure at stress (s-UCP), in the diagnosis and severity of female stress urinary incontinence (SUI). Methods: A total of 400 women without neurological disorders were included in this observational study. SUI was diagnosed using the International Continence Society definition, and severity was assessed using a validated French questionnaire, the Mesure du Handicap Urinaire. The perineal examination consisted of rating the strength of the levator ani muscle (0–5) and an assessment of bladder neck mobility using point Aa (cm). The urodynamic parameters were maximal urethral closure pressure at rest, s-UCP, Valsalva leak point pressure (cm H2O), and pressure transmission ratio (%). Results: Of the women, 358 (89.5%) were diagnosed with SUI. The risk of SUI significantly increased as s-UCP decreased (odds ratio [OR], 0.92; 95% confidence interval, 0.88–0.98). The discriminative value of the measure was good for the diagnosis of SUI (area under curve>0.80). s-UCP values less than or equal to 20 cm H2O had a sensitivity of 73.1% and a specificity of 93.0% for predicting SUI. The association between s-UCP and SUI severity was also significant. Conclusions: s-UCP is the most discriminative measure that has been identified for the diagnosis of SUI. It is strongly inversely correlated with the severity of SUI. It appears to be a specific SUI biomarker reflecting both urethral sphincter competence and urethral support.
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Fabien Gabriel,Frederik De Belie,Pascal Druyts,Xavier Neyt,Philippe Lataire 전력전자학회 2011 ICPE(ISPE)논문집 Vol.2011 No.5
Last decades, important progress have been made in sensorless control methods based on the tracking of magnetic anisotropies linked to the rotor. These methods allow to estimate the rotor position at low speed down to standstill. The magnetic anisotropy is generally approached by a sinusoidal shaped function. However, the theory must be adapted in case of additional harmonic content in the anisotropy function. This paper specifically addresses the problem for the surface-mounted permanent-magnet brushless DC machines with diametric windings. They present a peculiar magnetic anisotropy that suggests a simple method to detect the inversion of the magnetic field as a replacement to the dedicated sensors which are often used.
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