고환에 발생한 표피양낭

정기욱,정웅교,김재웅,이홍우,강성학 大韓泌尿器科學會 2001 Korean Journal of Urology Vol.42 No.9

수컷 쥐 요도의 해부학적 특징 및 절편 형태에 따른 요도괄약근의 수축력 비교

정웅교,조수연,이지열 大韓泌尿器科學會 2002 Korean Journal of Urology Vol.43 No.10

아노다이징 표면 처리된 항공기 저장조의 내면 정밀연마를 위한 제조공정의 개선

김웅범(Woong-Beom Kim),조영태(Young-Tae Cho),정윤교(Yoon-Gyo Jung),최정동(Jeong-Dong Choi) 한국기계가공학회 2016 한국기계가공학회지 Vol.15 No.2

Airplane reservoirs made of Al7075 are coated with an anodizing layer to maintain precision, air tightness and corrosion resistance. It is commonly required that the inner surface roughness of the reservoir be less than an average 0.2㎛ to maintain stable oil pressure. Even though precision polishing is necessary to achieve this quality it is not easy. Inner surface roughness is not uniform and the quality of the product is irregular because most of the work is done by hand. The purpose of this study is to design an exclusive polishing machine and to determine the standard cutting condition and polishing condition necessary for good inner surface roughness and to improve workefficiency.

이하선 종양으로 오인된 이하선 결핵 1예

배교한(Gyo Han Bae),김정석(Jung Suk Kim),노웅재(Woong Jae Noh) 대한두경부종양학회 2020 대한두경부 종양학회지 Vol.36 No.1

Tuberculosis of parotid gland is extremely rare, even in countries where tuberculosis is endemic. It can occur by systemic dissemination from a distant focus or as primary involvement. Because of the clinical and radiological similarity, parotid tumor and parotid inflammatory disease take priority over the tuberculosis of parotid when it comes to differential diagnosis. As a result, clinicians often fail to make a timely diagnosis of tuberculosis of parotid gland in patient with a slowly growing parotid mass. However, its treatment is primarily medical if the positive diagnosis is well established. We have recently experienced a case of tuberculosis of parotid gland that was considered as the benign tumor preoperatively, but which was confirmed as tuberculosis of parotid gland after extracapsular dissection. We report it with a review of literature.

Quantitative PCR for Etiologic Diagnosis of Methicillin-Resistant Staphylococcus aureus Pneumonia in Intensive Care Unit

( Sun Jung Kwon ),( Taeh Yeon Jeon ),( Dong Wook Seo ),( Moon Joon Na ),( Eu Gene Choi,),( Ji Woong Son ),( Eun Hyung Yoo ),( Chang Gyo Park ),( Hoi Young Lee ),( Ju Ock Kim ),( Sun Young Kim ),( Jae 대한결핵 및 호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.72 No.3

Background: Ventilator-associated pneumonia (VAP) requires prompt and appropriate treatment. Since methicillin- resistant Staphylococcus aureus (MRSA) is a frequent pathogen in VAP, rapid identification of it, is pivotal. Our aim was to evaluate the utility of quantitative polymerase chain reaction (qPCR) as a useful method for etiologic diagnoses of MRSA pneumonia. Methods: We performed qPCR for mecA, S. aureus-specific femA-SA, and S. epidermidis-specific femA-SE genes from bronchoalveolar lavage or bronchial washing samples obtained from clinically-suspected VAP. Molecular identification of MRSA was based on the presence of the mecA and femA-SA gene, with the absence of the femA-SE gene. To compensate for the experimental and clinical conditions, we spiked an internal control in the course of DNA extraction. We estimated number of colony-forming units per mL (CFU/mL) of MRSA samples through a standard curve of a serially-diluted reference MRSA strain. We compared the threshold cycle (Ct) value with the microbiologic results of MRSA. Results: We obtained the mecA gene standard curve, which showed the detection limit of the mecA gene to be 100 fg, which corresponds to a copy number of 30. We chose cut-off Ct values of 27.94 (equivalent to 1×104 CFU/mL) and 21.78 (equivalent to 1×105 CFU/mL). The sensitivity and specificity of our assay were 88.9% and 88.9% respectively, when compared with quantitative cultures. Conclusion: Our results were valuable for diagnosing and identifying pathogens involved in VAP. We believe our modified qPCR is an appropriate tool for the rapid diagnosis of clinical pathogens regarding patients in the intensive care unit.

Quantitative PCR for Etiologic Diagnosis of Methicillin-Resistant Staphylococcus aureus Pneumonia in Intensive Care Unit

Kwon, Sun-Jung,Jeon, Tae-Hyeon,Seo, Dong-Wook,Na, Moon-Joon,Choi, Eu-Gene,Son, Ji-Woong,Yoo, Eun-Hyung,Park, Chang-Gyo,Lee, Hoi-Young,Kim, Ju-Ock,Kim, Sun-Young,Kang, Jae-Ku The Korean Academy of Tuberculosis and Respiratory 2012 Tuberculosis and Respiratory Diseases Vol.72 No.3

Background: Ventilator-associated pneumonia (VAP) requires prompt and appropriate treatment. Since methicillin-resistant Staphylococcus aureus (MRSA) is a frequent pathogen in VAP, rapid identification of it, is pivotal. Our aim was to evaluate the utility of quantitative polymerase chain reaction (qPCR) as a useful method for etiologic diagnoses of MRSA pneumonia. Methods: We performed qPCR for mecA, S. aureus-specific femA-SA, and S. epidermidis-specific femA-SE genes from bronchoalveolar lavage or bronchial washing samples obtained from clinically-suspected VAP. Molecular identification of MRSA was based on the presence of the mecA and femA-SA gene, with the absence of the femA-SE gene. To compensate for the experimental and clinical conditions, we spiked an internal control in the course of DNA extraction. We estimated number of colony-forming units per mL (CFU/mL) of MRSA samples through a standard curve of a serially-diluted reference MRSA strain. We compared the threshold cycle (Ct) value with the microbiologic results of MRSA. Results: We obtained the mecA gene standard curve, which showed the detection limit of the mecA gene to be 100 fg, which corresponds to a copy number of 30. We chose cut-off Ct values of 27.94 (equivalent to $1{\times}10^4$ CFU/mL) and 21.78 (equivalent to $1{\times}10^5$ CFU/mL). The sensitivity and specificity of our assay were 88.9% and 88.9% respectively, when compared with quantitative cultures. Conclusion: Our results were valuable for diagnosing and identifying pathogens involved in VAP. We believe our modified qPCR is an appropriate tool for the rapid diagnosis of clinical pathogens regarding patients in the intensive care unit.

최근 5년간 요로감염의 원인균 및 항생제 감수성

김세웅,임필빈,정웅교,이승주,이지열,조용현,윤문수 대한화학요법학회 2002 대한화학요법학회지 Vol.20 No.3

배경 : 최근 요로감염 원인균에 대한 내성 증가로 항생제 감수성에 변화를 가져와 요로감염 환자에게 경험적 1차 치료를 위한 항생제 선택에 어려움을 주고 있다. 단순 및 복잡성 요로감염으로 진단 받은 환자들을 대상으로 원인균과 그에 따른 항생제의 감수성을 살펴봄으로써 향후 단순 및 복잡성 요로감염에 대한 항생제의 선택에 도움을 받고자 한다. 대상 및 방법 : 1996년 6월부터 2001년 5월까지 요배양 검사상 요로 감염균이 10^5cfu/ml 이상의 집락이 형성된 200명을 대상으로 해부학적 또는 구조적인 장애 유무에 따라 단순 요로감염 및 복잡성 요로 감염으로 나누어 각각의 원인균과 그에 따른 항생제의 감수성을 후향적으로 분석하였다. 결과 : 복잡성 요로감염의 가장 흔한 원인질환은 신경인성 방광이었다. 단순 요로감염의 가장 흔한 원인균은 E. coli (61.35%)였고 복잡성 요로감염에서는 E. coli 이외의 균이 E. coli 보다 더 흔한 원인균이었다(58.9%). 단순 및 복잡성 오료감염 중 그람 양성균에서는 vancomycin, penicillin 이 높은 감수성을 보인 반면 ciprofloxacin, imipenem이 낮은 감수성을 보였고 그람음성균에서는 amikacin, imipenem이 높은 감수성을 보인 반면 ampicillin, bactrim이 낮은 감수성을 보였다. 결론 : 단순 및 복잡성 요로 감염의 주 원인균으로 그람 음성균주 특히, Ecoli에 의한 감염이 많은 비중을 차지하고 있으나 빈도가 점차적으로 감소하는 추세이다. 또한 병원성 감염 및 도뇨관의 장기 유치에 따른 교대균의 증가, 비병원성 세균의 출현 등으로 인한 E. coli 이외의 기타 그람음성균 및 그람양성균의 증가하는 추세이다. 향후 임상에서 요로감염의 일치 치료제로 많이 사용되고 있는 ampicillin과 bactrim 등의 항생제의 감수성이 낮으므로 사용시 필요하다고 사료된다. Backround : The increasing frequency of failure of urinary tract infections (UTIs) may be due to emerging resistance to commonly prescribed antimicrobials. We studied the causative microorganisms and their antibiotic sensitivities in uncomplicated and complicated UTIs. Methods : We analyzed 219 microorganisms and their antibiotic sensitivities of 200 outpatients who had more than 10^5cfu/ml on urine from June 1996 to May 2001 retrospectively. The patients weredivided into 2 groups, uncomplicated UTI group and commplicated UTI group according to with or without underlying disease. Results : The most common underlying disease of complicated UTI was neurogenic bladder. The most common pathogenic microorganism was Escherichia coli (E. coli) (61.35%) in uncomplicated UTI group but in complicated UTI, non-E, coli(58.9%) was more common than E. coli. In uncomplicated and complicated UTI, vancomycin, penicillin showed relatively higher sensitivity of gram positive organisms, while ciprofloxacin, imipenem showed relatively lower sensitivity, and imipenem, amikacin showed relatively higher sensitivity of gram negative organisms, while bactrim, amipicillin showed relatively lower sensitivity. Conclusion : We consider that gram negative microorgansisms, especially E. coli, is the main cause of UTI. But, we should concern about the increase of gram positive organsms and other gram negative organisms besides E. coli. Bactrim, amipicllin which were prescribed empirically in UTIs, showed relatively lower sensitivity. Regarding tom the choice of adequate drug in the treatment of UTI, it is necessary to consider the change of pathologic microorganisms.

A 40 Kb Genomic Deletion Including tmie (Transmembrane Inner Ear Protein) Gene Causes Deafness, Circling and Head Tossing in Circling Mice

Kyoung In Cho,Jeong Woong Lee,Eun Ju Lee,Sol Ha Hwang,Myoung Ok Kim,Sung Hyun Kim,Jun Hong Park,Boo Kyoung Jung,Hee Chul Kim,Jun-Gyo Suh,Yang-Seok Oh,Zae Young Ryoo 한국동물생명공학회(구 한국동물번식학회) 2004 Reproductive & Developmental Biology(Supplement) Vol.28 No.2s

차세대 디스플레이 기술의 예측에 관한 연구

남기웅(Nam, Ki-Woong),박상성(Park, Sang-Sung),신영근(Shin, Young-Geun),정원교(Jung, Won-Gyo),장동식(Jang, Dong-Sik) 한국산학기술학회 2009 한국산학기술학회논문지 Vol.10 No.10

본 논문에서는 차세대 디스플레이 기술에 대해서 기술의 추세를 예측하였다. 차세대 디스플레이 기술은 최 근에 급부상 하는 기술로 연구개발을 수행하는데 있어 추후 연구 방향을 설정하고 기술전략을 세우는데 불확실성을 줄여주기 위해 기술의 미래 발전 방향이나 추세에 대해서 예측을 해 보는 것이 중요하다. 이렇게 함으로써 연구개발 목표를 좀 더 명확히 설정할 수 있고 불필요한 투자를 방지할 수 있다. 본 논문에서는 차세대 디스플레이 기술에 대 해서 특허 데이터를 사용하여 정량적인 예측을 수행하였다. 예측 방법으로는 Gompertz, Logistic, Bass모형을 사용하였 다. 이 세 모형들은 과거 시장에서의 제품의 확산과정을 설명하는데 사용되었던 모형이다. Gompertz, Logistic모형은 시장의 수요예측 뿐만 아니라 기술의 수요예측에도 주로 쓰였기 때문에 본 논문에서도 이 두 모형을 적용하였다. 하 지만 Gompertz, Logistic모형은 시장에서의 내부 효과에 의한 확산만을 반영한 모형이고 성장의 상한 값을 추정하는 데 있어 추정이 쉽지 않다는 단점이 있다. 기술의 수요도 시장에서의 제품의 확산처럼 기술혁신에 의한 외부 효과와 산업으로 전파될 때의 내부효과가 함께 수요의 확산에 영향을 끼칠 것이라고 판단하여 본 논문에서는 시장에서의 제 품 확산의 외부효과와 내부효과를 동시에 고려한 Bass모형도 함께 적용하여 예측을 수행하였다. 또한 Gompertz, Logistic 모형의 상한 값을 Bass모형을 통해 객관적으로 추정하여 예측을 수행함으로써 두 모형의 단점을 보완하였다. This paper presents study on technological forecasting of Next-Generation Display technology. Next-Generation Display technology is one of the emerging technologies lately. So databases on patent documents of this technology were analyzed first. And patent analysis was performed for finding out present technology trend. And the forecast for this technology was made by growth curves which were obtained from forecast models using patent documents. In previous study, Gompertz, Logistic, Bass were used for forecasting diffusion of demand in market. Gompertz, Logistic models which were often used for technological forecasting, too. So, two models were applied in this study. But Gompertz, Logistic models only consider internal effect of diffusion. And it is difficult to estimate maximum value of growth in two models. So, Bass model which considers both internal effect and external effect of diffusion was also applied. And maximum value of growth in Gompertz, Logistic models was estimated by Bass model.

복압성요실금 환자의 진단에서 동적 자기공명영상의 유용성

이지열,김세웅,박왕진,정웅교,이승주,정승은,조용현,윤문수 大韓泌尿器科學會 2001 Korean Journal of Urology Vol.42 No.11