비정상 질확대경검사 소견을 보이는 환자에서 환상투열요법의 직접적 적용에 관한 연구

우헌탁,이철민,박교훈,조용균,최훈,김복린,이홍균 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.2

Objective: Large Loop Excision of the Transformation Zone (LLETZ) has been widely used for evaluating cervical dysplasia/cancer. We performed this study to evaluate if colposcopically suspected cervical high-grade dysplasia or cancer could be directly evaluated and treated with LLETZ. Methods: 93 women who were scheduled for colposcopic evaluation because of an abnormal cervical cytology report were included in the study in Sanggye Paik Hospital from Jan to Dec 2001. Mean age of the study population was 38.6±9.0. colposcopy directed punch biopsy was not performed and histologic diagnosis was made by LLETZ. Sensitivity and specificity of colposcopic evaluation was calculated and compared with those of cervical cytology. Results: On histopathological examination by LLETZ, 11(11.8%) patients had invasive cancers including 3(3.2%) adenocarcinomas. The sensitivity and specificity of colposcopy for the detection of cervical dysplasia or cancer was 71.7% and 72.3% respectively, wile those of cytology was 56.5% and 74.5% respectively. Conclusion: LLETZ may be adequately performed for the diagnosis and treatment of cervical dysplasia/cancer based on the results of pap smear and colposcopy without punch biopsy. Cost benefit might be anticipated while cost-effectiveness analysis is necessary in the future.

열대 원예작물의 특성과 재배법에 관한 조사

정삼택,이우승,김익홍 경북대학교 1987 새마을 硏究論叢 Vol.7 No.-

This investigation was conducted to know the characteristics and cultivation method of some tropical crops; fruit tree, vegetable and ornamental flowers growing in Tropical regions by literatures. 1) Most of fruits were utilized as raw-fruit itself and processing techniques are needed for the merchandise. Some fruit is lack of cultivation method. Pine apple and banana are the most common fruit in these regions. These fruit products can be exported to the temperate zone regions for the net-income of the farmers. 2) Vegetables are cultivated for the part of vitamin supply and on the whole, cultivation method is underdeveloped yet. But some vegetables are grown for the industrial oil, medicine manufacture, feed forage and green manure. 3) Ornamental flowers are grown for the cutflower and garden flower. From these results, It is believed that introduction and adaptability test must be conducted for the increased net-income of Korean farmers.

Holstein種의 血液化學値에 關한 硏究 : -Ⅰ. 成牝牛의 血液化學値- -Ⅰ. Blood Chemical Values of Adult Cows -

李載洪,林貞澤,韓邦根,金宇權 全南大學校 農漁村開發硏究所 1981 農業科學技術硏究 Vol.16 No.1

國內에서 飼育되고 있는 Holstein種成牝牛의 血液化學値를 얻고자 全南地域에서 飼育되고 있는 外觀上 健康하다고 認定된 經産牛 385頭를 對象으로 血液化學値를 調査檢討하여 다음과 같은 結論을 얻었다. 1. 平均血淸TP量은 7.35(5.10∼10.20)g/100㎖이었으며 年令의 增加에 따라서 漸漸 증가하는 傾向이 있었다. 2. 平均血淸Alb量은 3.51(2.50∼4.40)g/100㎖이었으며 年令別 差異는 認定할수 없었다. 3. 平均血淸Glb量은 3.84(1.40∼7.20)g/100㎖이었으며 年令의 增加에 따라서 漸漸 증가하는 傾向이 있었다. 4. 平均血淸 A/G比는 0.91(0.43∼2.64)이었으며 年令의 增加에 따라서 漸漸 증가하는 傾向이 있었다. 5. 平均血淸 cholesterol量은 179.38(46.4∼336.0)g/100㎖이었으며 年令의 增加에 따라 增加하여 4年牛를 頂点으로 다시 下向의 傾向을 나타내고 있었다. 6. 平均血淸 glucose量은 39.38(27.0∼57.3)㎎/100㎖로 낮았으며 年令別로 特徵的인 것은 發見할수 없었다. 7. 平均血淸 magnesium量은 2.72(0.20∼8.46)㎎/100㎖이었으며 老令牛에서 magnesium의 減少가 顯著하였다. 8. 平均血淸 calcium量은 8.69(6.34∼16.83)㎎/100㎖로 全般的으로 낮은 량이었으며 年令別 差異는 認定할수 없었다. 9. 平均血淸無機燐量은 5.88(3.50∼9.76)㎎/100㎖이었으며 年令別로 特徵的인 것은 發見할수 없었다. 10. 平均血淸Ca/P比는 1.48(0.68∼2.64)이었으며 年令別로 特徵的인 것은 發見할수 없었다. 11. 平均血淸 potassium量은 18.95(13.69∼24.24)㎎/100㎖이었으며 年令別 差異는 認定할수 없었다. 12. 平均血淸 sodium量은 315.90(282.86∼361.05)10.20)㎎/100㎖이었으며 年令別로 特徵的인 것은 發見할수 없었다. 13. 平均血淸 chloride量은 354.64(299.97∼361.05)㎎/100㎖이었으며 年令別 差異点은 發見할수 없었다. The present study was conducted to determine the blood chemical values of adult Holstein cows in Korea. Samples of blood were taken from 385 healthy cows in Chonnam province, and the results obtained are summarized as follows. 1. Mean serum totalprotein content was 7.35(5.10∼10.20)g/100㎖;it in creased with age. 2. Mean serum albumin content was 3.51(1.40∼4.40)g/100㎖;no differences were found between age groups in the serum albumin content. 3. Mean serum globulin content was 3.84(1.40∼7.20)g/100㎖; it increased with age. 4. Mean serum albumin/globulin ratio was 0.91(0.43∼2.64);it decreased with age. 5. Mean serum glucose concentration was 179.38(46.4∼336.0)g/100㎖;it increased up to 4 years of age and thereafter it decreased with age. 6. Mean serum glucose concentration was 39.38(27.0∼57.3)㎎/100㎖, which was low compared with other results. No differences were found in the glucose concentration between age groups. 7. Mean serum magnesium concentration was 2.72(0.20∼8.46)㎎/100㎖;it decreased significantly in older cows. 8. Mean serum calcium concentration was 8.69(6.34∼16.83)㎎/100㎖, which was low compared with other results. No differences were found in the calcium concentrati on between age groups. 9. Mean serum inorganic phosphate concentration was 5.88(3.50∼9.76)㎎/100㎖;no differences were found in the inorganic phosphate concentration between age groups. 10. Mean serum calcium/phosphate(Ca/P) ratio was 1.48(0.68∼2.64);no differences were found in the Ca/P ratio between age groups. 11. Mean serum potassium concentration was 18.95(13.69∼24.24)㎎/100㎖;no differences were found in the potassium concentration between age groups. 12. Mean serum sodium concentration was 315.90(282.86∼361.05)10.20)㎎/100㎖;no differences were found in the sodium concentration between age groups. 13. Mean serum chloride concentration was 354.64(299.97∼361.05)㎎/100㎖;no differences were found in the cholride concentration between age groups.

축우 부루셀라병의 ELISA 진단법에 관한 연구

임윤규,이두식,박전홍,양기천,김승호,김공식,현관종,김우택,이영순 濟州大學校 農科大學 動物科學硏究所 1993 動物科學論叢 Vol.8 No.1

Enzyme-linked Immuno sorbent Assay (ELISA) for the serological diagnosis oi Bruceiia abortus was developed and compared with plate aggluhnation test Cell wall antigen was extracted from Brucella abortus 1119-3 by sonicabon and with a sodium deoxychlate solution Optimum protein concentra tion of coating antigen 0.4㎍/100㎕ protein on each microtiter plate well. Horse radish peroxidase(HRP) labled protein-G was used as a tracer of reacted antibodies ELISA confirmed the agreeable results of 40 rases out of 43 cases by plate aggulutination test ELISA diagnosed positive cases (10 out of 12) and negatiw cases (1 out of 12) with dubious sera by plate agglutination test From this results EL ISA could be used for the early diagnostic tools of Brucellosis in cattle.

저온 농축법에 의한 극미량 성분 가스분석

이택홍(Lee Taeck-Hong),홍소영(Hong So Young),정우찬(Jung Woo Chan),김영락(Kim Young Rak),서정우(Suh Jung Woo),한주탁(Han Ju Tack),박두선(Park Doo Seon),손무룡(Son Moo Ryong) 한국가스학회 1997 한국가스학회 학술대회논문집 Vol.1997 No.9

Release of Sphingosine-l-Phosphate from Platelets that isIncreased by Enhancement of Platelet Sensitivity in Hypercholesterolemia : Roll of Sphingosine -l-Phospate on the Development of Atherosclerosis

HONG JIN TAE,SON DONG JU,LEE HYOUNG WOO,SHIN HYEOUN WOO,LEE JUNG JIN,KIM TAE MYEOUNG,HWANG SEOCK YEON,KIM TACK JOONG,YOO HWAN SOO,YUN YEO PYO 大韓藥學會 2006 大韓藥學會 總會 및 學術大會 Vol.2006 No.2

미숙아 및 저체중아에 대한 임상적 고찰

김우택,이경옥,김행미,안두홍 慶北大學校 醫科大學 1986 慶北醫大誌 Vol.27 No.3

A clinical observation was performed on 185 cases of prematurity and low birth weight infants(LBW) who admitted to K.N.U.H. during the past 10 years from Jan. 1976 to Dec. 1985. The incidence of the premature LBW was 76.2%(141 cases) and the sex ratio of male to female was 1.6:1. Concomitant maternal diseases were plasenta previa 21 cases, toxemia 20 cases etc. It was noted that in more than half of these infants the gestational age distributed from 32 to 36 weeks and the birth weight from 1750 to 2250 gm. The mortality rate among the premature and LBW infants was 11.9% and the causes of death were IRDS(45.4%), sepsis(27.2%) and intracranial hemorrhage(18.1%) in the order of frequency. There were neonatal complications such as jaundice(47.0%), hypocalcemia(40.5%), sepsis(30.3%), hypoglycemia(15.7%) and IRDS(10.8%) in the order of frequency. The prematurity and LBW who lost less than 10% of their birth weights were 67.5% and who lost their birth weight more than 15% were 11.9%. 70.8% of prematurity or LBW regain their birth weight within 2week after birth. The smaller the birth weight, the slower the regain of birth weight.

소아에서 human metapneumovirus와 respiratory syncytial virus에 의한 호흡기질환의 비교

정우진 ( Woo Jin Chung ),강성실 ( Sung Shil Kang ),방경원 ( Kyong Won Bang ),전윤홍 ( Yoon Hong Chun ),윤종서 ( Jong Seo Yoon ),김현희 ( Hyun Hee Kim ),김진택 ( Jin Tack Kim ),이준성 ( Joon Sung Lee ) 대한소아알레르기호흡기학회 1991 소아알레르기 및 호흡기학회지 Vol.1 No.2

Purpose: Human metapneumovirus (hMPV) is known to result in clinical manifestation similar to respiratory syncytial virus (RSV) in children. But some recent studies showed different features. This study compared the clinical manifestation of respiratory disease between hMPV and RSV. Methods: A total of 801 children who admitted to Seoul St. Mary’s Hospital for respiratory infection from January to June, 2012 were enrolled. Respiratory viral polymerase chain reaction (PCR) using nasopharyngeal swab was performed in all children. We grouped hMPV positive children and RSV positive children and compared clinical features between them by retrospective chart review. Results: Among 801 children, 365 showed one virus PCR positive with 44 showing hMPV and 41 showing RSV. Respiratory diseases were upper respiratory infection, acute bronchitis, acute bronchiolitis and pneumonia. The peak season was March and April for hMPV and February and March for RSV. Fever incidence, fever duration and neutrophil percent of complete blood cell count were higher in hMPV group than RSV group (P<0.05). The mean age of hMPV group was higher than RSV group (P<0.05). But in acute bronchiolitis children, there was no mean age difference between two group. Acute bronchiolitis incidence declined with increased age for both group (P<0.05). The hMPV group showed relatively lower bronchiolitis and higher pneumonia incidence than RSV group, suggesting relation with age. Conclusion: Respiratory infection by hMPV developed at late winter and spring, slightly later than RSV and at older age. The lower incidence of acute bronchiolitis for hMPV infection than RSV is maybe due to older age than RSV. (Allergy Asthma Respir Dis 2013;1:157-163)

소아중환자실 호흡기질환 입실 환자의 재입실 위험 요소

정우진 ( Woo Jin Chung ),윤다혜 ( Da Hye Yoon ),이의경 ( Eui Gyung Lee ),방경원 ( Kyong Won Bang ),김환수 ( Hwan Su Kim ),전윤홍 ( Yoon Hong Chun ),윤종서 ( Jong Seo Yoon ),김현희 ( Hyun Hee Kim ),김진택 ( Jin Tack Kim ),이준성 ( 대한천식알레르기학회 2014 Allergy Asthma & Respiratory Disease Vol.2 No.2

Purpose: Children admitted to pediatric intensive care unit (PICU) with respiratory tract disease, often have a tendency to be readmitted to PICU with disease progression. We studied the risk factors for readmission to PICU, with respiratory disease progression. Methods: Among 286 children admitted to Seoul St. Mary’s Hospital PICU from April 2009 to March 2012, 129 children admitted with respiratory tract disease were enrolled. We grouped the children readmitted to PICU with respiratory tract disease progression within 2 weeks (readmission group), and the others (control group). We compared basic and respiratory tract disease characteristics at initial PICU admission between them, by retrospective chart review. Results: Among 129 children, 8 were included in the readmission group, and 121 in the control group. Mortality and underlying disease incidence were higher in the readmission group (P=0.003 and P=0.033, respectively). The readmission group showed higher parenchymal lung disease incidence, and lower initial saturation by pulse oxymeter (SpO2)/fraction of inspiratory oxygen (FiO2), despite underlying disease influence (P=0.035 and P=0.041, respectively). Logistic regression on the underlying disease and respiratory variables showed no single factor with a significantly independent influence on readmission, but parenchymal lung disease had more independent influence. Conclusion: For PICU readmission with respiratory tract disease progression, parenchymal lung disease and lower initial SpO2/FiO2 can be a risk factor despite underlying disease influence. Underlying disease and each respiratory characteristic were not significantly independent risk factors, suggesting a correlation of factors. But, parenchymal lung disease can be a more independent risk factor. (Allergy Asthma Respir Dis 2014;2:128-133)

소아 76명에서의 굴곡성 기관지 내시경술: 적응증, 이득 그리고 합병증

배우리 ( Woo Ri Bae ),문경필 ( Kyung Pil Moon ),방경원 ( Kyong Won Bang ),김환수 ( Hwan Soo Kim ),전윤홍 ( Yoon Hong Chun ),윤종서 ( Jong Seo Yoon ),김현희 ( Hyun Hee Kim ),김진택 ( Jin Tack Kim ) 대한천식알레르기학회 2016 Allergy Asthma & Respiratory Disease Vol.4 No.3

Purpose: This study was performed to investigate the indications, yield, and complications of flexible bronchoscopy for respiratory disease in children compared to earlier domestic studies and to examine if any differences existed in comparison to international studies. Methods: The medical records of 100 cases of flexible bronchoscopy that were performed in 76 patients at the Department of Pediatrics of The Catholic University of Korea, Seoul St. Mary``s Hospital from June 16, 2010 to August 6, 2013 were reviewed. Results: A total of 76 patients (50 males and 26 females) were included in the study. The most common indication of flexible bronchoscopy was persistent pneumonia or pneumonia in immunocompromised patients (53 cases). The object of flexible bronchoscopy was accomplished in 65 of 100 cases, and, the treatment was changed in 24 of 65 cases. The most common abnormal finding was tracheomalacia that was found in 18 cases. In 67 cases where bronchoalveolar lavage was performed, bacteria were identified in 47 cases, fungi in 9 cases, and viruses in 22 cases. Complications occurred in 8 cases. Conclusion: Compared to earlier domestic studies, there was no significant change in diagnostic approaches and therapeutic improvement. However, this study showed that flexible bronchoscopy appears to be safe in patients with hemato-oncologic disease. Compared to international studies, the occurrence of complications due to flexible bronchoscopy was relatively low. (Allergy Asthma Respir Dis 2016;4:181-187)