Wireless Synchronous Transfer of Power and Reverse Signals

Li, Yang,Li, Yumei,Feng, Shaojie,Yang, Qingxin,Dong, Weihao,Zhao, Jingtai,Xue, Ming The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.3

Wireless power transfer via coupled magnetic resonances has been a hot research topic in recent years. In addition, the number of related devices has also been increasing. However, reverse signals transfer is often required in addition to wireless power transfer. The structure of the circuit for a wireless power transfer system via coupled magnetic resonances is analyzed. The advantages and disadvantages of both parallel compensation and series compensation are listed. Then the compensation characteristics of the inductor, capacitor and resistor were studied and an appropriate compensation method was selected. The reverse signals can be transferred by controlling the compensation of the resistor. In addition, it can be demodulated by extracting the change of the primary current. A 3.3 MHz resonant frequency with a 100 kHz reverse signals transfer system platform was established in the laboratory. Experimental results demonstrate that wireless power and reverse signals can be transferred synchronously.

Wireless Synchronous Transfer of Power and Reverse Signals

Yang Li,Yumei Li,Shaojie Feng,Qingxin Yang,Weihao Dong,Jingtai Zhao,Ming Xue 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.3

Wireless power transfer via coupled magnetic resonances has been a hot research topic in recent years. In addition, the number of related devices has also been increasing. However, reverse signals transfer is often required in addition to wireless power transfer. The structure of the circuit for a wireless power transfer system via coupled magnetic resonances is analyzed. The advantages and disadvantages of both parallel compensation and series compensation are listed. Then the compensation characteristics of the inductor, capacitor and resistor were studied and an appropriate compensation method was selected. The reverse signals can be transferred by controlling the compensation of the resistor. In addition, it can be demodulated by extracting the change of the primary current. A 3.3 MHz resonant frequency with a 100 kHz reverse signals transfer system platform was established in the laboratory. Experimental results demonstrate that wireless power and reverse signals can be transferred synchronously.

Adaptive Event-triggered Output Feedback Control for Large-scale Nonlinear Time-delay Systems With Dead-zone Input

Weihao Pan,Xianfu Zhang,Hanfeng Li 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.7

This paper focuses on the event-triggered output feedback control problem for a class of large-scale nonlinear time-delay systems with asymmetric dead-zone input. Without knowing the precise priori knowledge of dead-zone parameters, an event-triggered output feedback control strategy is developed based on the dynamic gain design approach. It is proved by the Lyapunov analysis that all signals of the closed-loop system are globally bounded and the system states converge to a bounded region which is adjustable. Moreover, the Zeno behavior is avoided. Compared with the existing results, the considered nonlinear system allows more general growth condition, and the proposed event-triggered control strategy effectively handles dead-zone input, time delay and the more general nonlinear characteristic. Finally, an example is used to illustrate the validity of the proposed control strategy.

Multi-fidelity modeling and analysis of a pressurized vessel-pipe-safety valve system based on MOC and surrogate modeling methods

Song Xueguan,Li Qingye,Liu Fuwen,Zhou Weihao,Zong Chaoyong 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.8

A pressurized vessel-pipe-safety valve (PVPSV) combination is a commonly used configuration in nuclear power plants, and a good numerical model is essential for the system design, sizing and performance optimization. However, owing to the large-scale and cross-scale features, it is still a challenge to build a system level numerical model with both high accuracy and efficiency. To overcome this, a novel system level modeling method which can synthesize the advantages of various models is proposed in this paper. For system modeling, the analytical approach, the method of characteristics (MOC) and the surrogate model approach are respectively adopted to predict the dynamics of the pressure vessel, the connecting pipe and the safety valve, and different models are connected through data interfaces. With this system model, dynamic simulations were carried out and both the stable and the unstable system responses were obtained. For the model verification purpose, the simulation results were compared with those obtained from experiments and full CFD simulations. A good agreement and a better efficiency were obtained, verifying the ability of the model and the feasibility of the modeling method proposed in this paper

Design optimization of a nuclear main steam safety valve based on an E-AHF ensemble surrogate model

Zong Chaoyong,Shi Maolin,Li Qingye,Liu Fuwen,Zhou Weihao,Song Xueguan 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.11

Main steam safety valves are commonly used in nuclear power plants to provide final protections from overpressure events. Blowdown and dynamic stability are two critical characteristics of safety valves. However, due to the parameter sensitivity and multi-parameter features of safety valves, using traditional method to design and/or optimize them is generally difficult and/or inefficient. To overcome these problems, a surrogate model-based valve design optimization is carried out in this study, of particular interest are methods of valve surrogate modeling, valve parameters global sensitivity analysis and valve performance optimization. To construct the surrogate model, Design of Experiments (DoE) and Computational Fluid Dynamics (CFD) simulations of the safety valve were performed successively, thereby an ensemble surrogate model (E-AHF) was built for valve blowdown and stability predictions. With the developed E-AHF model, global sensitivity analysis (GSA) on the valve parameters was performed, thereby five primary parameters that affect valve performance were identified. Finally, the ksigma method is used to conduct the robust optimization on the valve. After optimization, the valve remains stable, the minimum blowdown of the safety valve is reduced greatly from 13.30% to 2.70%, and the corresponding variance is reduced from 1.04 to 0.65 as well, confirming the feasibility and effectiveness of the optimization method proposed in this paper

Preparation and Properties Study of Composites

Yi Xiaoou,Xiong Weihao,Li Jian 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1

The particulate strengthened composites were prepared by a PM process to develop novel copper based composites with reasonable strength, high thermal conductivity and low thermal expansion coefficient. Microstructure of the composites was investigated by SEM; the tensile strength, elongation, thermal conductivity and thermal expansion coefficient (CTE) of the composites were examined. A comparative analysis of mechanical and thermal properties of various Cu-matrix composites currently in use was given and the strengthening mechanisms for the composites were discussed.

Alpha radionuclide-chelated radioimmunotherapy promoters enable local radiotherapy/chemodynamic therapy to discourage cancer progression

Jiajia Zhang,Feize Li,Yuzhen Yin,Ning Liu,Mengqin Zhu,Han Zhang,Weihao Liu,Mengdie Yang,Shanshan Qin,Xin Fan,Yuanyou Yang,Kun Zhang,Fei Yu 한국생체재료학회 2022 생체재료학회지 Vol.26 No.4

Background: Astatine-211 is an α-emitter with high-energy α-ray and high cytotoxicity for cancer cells. However, the targeted alpha therapy (TAT) also suffers from insufficient systematic immune activation, resulting in tumor metastasis and relapse. Combined immune checkpoint blockade (ICB) with chemodynamic therapy (CDT) could boost antitumor immunity, which may magnify the immune responses of TAT. This study aims to discourage tumor metastasis and relapse by tri-model TAT-CDT-ICB strategy. Methods: We successfully designed Mn-based radioimmunotherapy promoters (211At-ATE-MnO2-BSA), which are consisting of 211At, MnO2 and bovine serum albumin (BSA). The efficacy of 211At-ATE-MnO2-BSA was studied as monotherapy or in combination with anti-PD-L1 in both metastatic and relapse models. The immune effects of radioimmunotherapy promoters on cytotoxic T lymphocytes and dendritic cells (DCs) were analyzed by flow cytometry. Enzymelinked immunosorbent assay and immunofluorescence were used to explore the underlying mechanism. Results: Such radioimmunotherapy promoters could not only enhance the therapeutic outcomes of TAT and CDT, but also induce robust anti-cancer immune activity by activating dendritic cells. More intriguingly, 211At-ATE-MnO2-BSA could effectively suppress the growths of primary tumors and distant tumors when combined with immune checkpoint inhibitors. Conclusions: The tri-model TAT-CDT-ICB strategy provides a long-term immunological memory, which can protect against tumor rechallenge after eliminating original tumors. Therefore, this work presents a novel approach for TATCDT-ICB tri-modal cancer therapy with repressed metastasis and relapse in clinics.

Multifunctional Antibacterial and Hydrophobic Cotton Fabrics Treated with Cyclic Polysiloxane Quaternary Ammonium Salt

Jian Liu,Chaohong Dong,Dongdong Wei,Zheng Zhang,Weihao Xie,Qun Li,Zhou Lu 한국섬유공학회 2019 Fibers and polymers Vol.20 No.7

A novel polysiloxane quaternary ammonium salt (NCTSi) was synthesized and used as antibacterial andhydrophobic agent for cotton fabric. The chemical structures were characterized by FT-IR. The surface morphology of treatedcotton fabrics was characterized by scanning electron microscopy (SEM) and energy dispersive spectrometer (EDS). Thecotton fabrics treated with NCTSi showed excellent antibacterial properties against Gram-positive bacteria S. aureus andGram-negative bacteria E. coli. The E. coli antibacterial rate was about 99.52 % and the S. aureus antibacterial rate was about98.33 %, with only a slight decrease after 20 cycles of standard washing, to 91.43 % and 93.33 %, respectively. The inhibitionzone was 2 mm and 2.5 mm against E. coli and S. aureus when NCTSi concentration was 4 %. The treated cotton fabricsprovided excellent hydrophobic properties, and the water contact angle (WCA) reached 124.14 º compared to pure cottonfabrics. The mechanical properties and whiteness were also investigated. As a result of the performed modifications,multifunctional fabrics with a considerably increased hydrophobicity and high antibacterial property were obtained.

TRIM22 promotes the proliferation of glioblastoma cells by activating MAPK signaling and accelerating the degradation of Raf-1

Fei Xiaowei,Dou Ya-nan,Sun Kai,Wei Jialiang,Guo Qingdong,Wang Li,Wu Xiuquan,Lv Weihao,Jiang Xiaofan,Fei Zhou 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

The tripartite motif (TRIM) 22 and mitogen-activated protein kinase (MAPK) signaling pathways play critical roles in the growth of glioblastoma (GBM). However, the molecular mechanism underlying the relationship between TRIM22 and MAPK signaling remains unclear. Here, we found that TRIM22 binds to exon 2 of the sphingosine kinase 2 (SPHK2) gene. An ERK1/2-driven luciferase reporter construct identified TRIM22 as a potential activator of MAPK signaling. Knockout and overexpression of TRIM22 regulate the inhibition and activation of MAPK signaling through the RING-finger domain. TRIM22 binds to Raf-1, a negative regulator of MAPK signaling, and accelerates its degradation by inducing K48-linked ubiquitination, which is related to the CC and SPRY domains of TRIM22 and the C1D domain of Raf-1. In vitro and in vivo, an SPHK2 inhibitor (K145), an ERK1/2 inhibitor (selumetinib), and the nonphosphorylated mutant Raf-1S338A inhibited GBM growth. In addition, deletion of the RING domain and the nuclear localization sequence of TRIM22 significantly inhibited TRIM22-induced proliferation of GBM cells in vivo and in vitro. In conclusion, our study showed that TRIM22 regulates SPHK2 transcription and activates MAPK signaling through posttranslational modification of two critical regulators of MAPK signaling in GBM cells.

An Acid-/Base-Degradable Epoxy Resin Cured by 1,3,5-Triacroylamino- hexahydro-s-triazine Derivative

Lei Wang,Shijing Yan,Lei Zhang,Yuliang Mai,Weihao Li,Hao Pang 한국고분자학회 2021 Macromolecular Research Vol.29 No.7

The degradation and recycling of waste epoxy resin products is an urgent environmental problem. To solve this issue, we use acid-/base-degradable 1,1’,1"- (1,3,5-hexahydro-s-triazine-1,3,5-triyl) tris(3-ethylamino-propan-1-one) (TAHT-EA) as curing agent to introduce the hexahydro-s-triazine (HT) ring structure into the cross-linking network to prepare degradable epoxy resin. Specifically, 1,3,5-triacryloylhexahydro- 1,3,5-triazine (TAHT) and ethylamine quickly complete the Aza-Michael addition reaction at the interface of chloroform and water droplets under the catalysis of water. The FTIR spectra, NMR spectrum and mass spectrum show that mono- and bis-addition products of ethylamine coexist in the product in which the content of the primary addition product reaches 97%. TAHT-EA can be decomposed by acid and base solutions. Through NMR analysis of the degradation products, it can be explained that the degradation mechanisms are different. The breaking of amide bonds and HT rings in acid solution and the cracking of amide bonds in base solution are speculated to be the main mechanisms under these two different circumstances, respectively. We tested the mechanical, thermal and degradation properties of the epoxy resin cured by TAHT-EA, and compared it with the epoxy resin cured by 4,4'-diaminodiphenylmethane and triethylenetetramine. TAHT-EA-cured epoxy resin shows comparable mechanical properties with Young’s modulus up to 2.05 GPa and tensile strength up to 70.9 MPa. What is more, it degrades completely by 1 M H+/OH- solution at 60℃ within 36 h. Nevertheless, it exhibited a relatively low crosslinked density (633 mol/m3) and low heat resistance (the initial decomposition temperature is lower than 205℃). Overall, TAHT-EA cured epoxy resin has the potential to gradually replace traditional thermosetting resin, thereby solving the environmental problems caused by discarded epoxy resin products.