Breast Mass Detected During Cardiac Stress Testing Which Led to Correct Diagnosis and Treatment

Ullah Ihsan,Laghari Abid Hussain,Farhad Awais,Adnan Ghufran,Nagher Babar 아시아심장혈관영상의학회 2022 Cardiovascular Imaging Asia Vol.6 No.1

The incidental findings/artifacts identified on myocardial perfusion imaging (MPI) often warrant further evaluation to rule out possible malignant pathologies. In this case report, we describe an elderly lady who was advised to undergo MPI for cardiac risk stratification prior to a non-cardiac surgery. Her MPI showed a large-sized infarct. In addition, a nodule on the left side of her chest that demonstrated increased isotope uptake was identified incidentally. Further evaluation of this lesion revealed a histopathological diagnosis of intraductal carcinoma of the breast. This case highlights the importance of reporting and investigating all suspicious incidental MPI findings.

Multi-aging Effects on Vegetable Based Oils for Transformer Insulation in HV Systems

Khan Irfanullah,Abid Muhammad Ahtasham,Ullah Kaleem,Ullah Zahid,Haider Aun,Ahmad Farhan Ammar,Zia Zain,Ali Sahibzada Muhammad 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.5

Liquid insulation media is used for insulation and cooling purpose inside the transformer. Currently, transformers are using petroleum based mineral oil, which poses a serious hazardous environmental impact, since the mineral oil is non-renewable and non-biodegradable. Although, the increased cost and depleting nature of mineral oil cause an emergent need to use suitable alternatives to mineral oils that are biodegradable and environmentally friendly. In response to this resource issue, various vegetable oils, namely Sunfl ower oil, Soya bean oil, and a blend of Sunfl ower and Olive (BSO) oil are suitable alternatives for transformer insulation in high voltage systems. The afore-mentioned vegetable oils are subjected to multi-aging and comparative analysis is performed with mineral oil. Further, the dielectric and thermal properties of vegetable oils are tested before and after aging. Fourier Transform Infrared spectroscopy, water content, breakdown voltage, viscosity, fl ash point, tan delta, and pour point tests are performed on vegetable oils before and after aging. Finally, a comparative analysis of vegetable oils with mineral oil is provided to prove the effi cacy of the proposed vegetable oils. The BSO oil resulted in higher breakdown strength and good thermal behavior when subjected to the abovementioned various diagnostic measurement tests in comparison to other oils

Salicylic acid and kinetin mediated stimulation of salt tolerance in cucumber (Cucumis sativus L.) genotypes varying in salinity tolerance

Ali Raza Gurmani,Sami Ullah Khan,Amjad Ali,Tehseen Rubab,Timothy Schwinghamer,Ghulam Jilani,Abid Farid,Jinlin Zhang 한국원예학회 2018 Horticulture, Environment, and Biotechnology Vol.59 No.4

Greenhouse studies were undertaken to evaluate the genetic performance of two cucumber genotypes (Long Green and Summer Green) at four salinity levels (0, 25, 50, and 100 mM NaCl). Seeds were pretreated with 50 mg salicylic acid (SA) L−1 and 25 mg kinetin (Kin) L−1. Under hydroponic conditions, seed pretreatment with Kin significantly increased shoot and root dry biomass and reduced the salt injury index in both genotypes. SA reduced the salt injury index of Long Green cucumbers. In a pot experiment, Kin treatment reduced Na+ and increased K+ concentration, photosynthesis, and chlorophyll content in both genotypes, compared to SA under saline soil conditions. Kin treatment improved fruit yield in both genotypes, while SA had a statistically significant effect on Long Green fruit yield. The application of SA and Kin enhanced salinity tolerance in both genotypes by the activation of antioxidants, especially superoxide dismutase, peroxidase, and catalase, which offset oxidative injury. Summer Green exhibited better salt tolerance and improved osmoregulation that resulted in higher fruit yield than Long Green. It was concluded that cucumber genotypes differed in salt tolerance, and seed pre-treatment with Kin minimized salt stress injury, even in sensitive genotype which could sustain crop production under saline conditions.

Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in <i>ob/ob</i> and <i>db/db</i> transgenic mouse models

Ahmad, Ashfaq,Ali, Tahir,Kim, Min Woo,Khan, Amjad,Jo, Myeung Hoon,Rehman, Shafiq Ur,Khan, Muhammad Sohail,Abid, Noman Bin,Khan, Mehtab,Ullah, Rahat,Jo, Min Gi,Kim, Myeong Ok Elsevier 2019 clinical and experimental Vol.90 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>In metabolic disorders, adiponectin and adiponectin receptors (AdipoR1/R2) signaling has a key role in improving nonalcoholic fatty liver disease (NAFLD) in obesity-associated diabetes.</P> <P><B>Objective</B></P> <P>To the best of our knowledge, here, we reported for the first time the underlying mechanistic therapeutic efficacy of the novel osmotin, a homolog of mammalian adiponectin, against NAFLD in leptin-deficient <I>ob/ob</I> and <I>db/db</I> mice.</P> <P><B>Methods</B></P> <P>The <I>ob/ob</I> and <I>db/db</I> mice were treated with osmotin at a dose of 5 μg/g three times a week for two weeks. To co-relate the <I>in vivo</I> results we used the human liver carcinoma HepG2 cells, subjected to knockdown with small siRNAs of AdipoR1/R2 and PPARα genes and treated with osmotin and palmitic acid (P.A.). MTT assay, Western blotting, immunohistofluorescence assays, and plasma biochemical analyses were applied.</P> <P><B>Results</B></P> <P>Osmotin stimulated AdipoR1/R2 and its downstream APPL1/PPAR-α/AMPK/SIRT1 pathways in <I>ob/ob</I> and <I>db/db</I> mice, and HepG2 cells exposed to P.A. Mechanistically, we confirmed that knockdown of AdipoR1/R2 and PPARα by their respective siRNAs abolished the osmotin activity in HepG2 cells exposed to P.A. Overall, the <I>in vivo</I> and <I>in vitro</I> results suggested that osmotin protected against NAFLD through activation of AdipoR1/R2 and its downstream APPL1/PPAR-α/AMPK/SIRT1 pathways as shown by the reduced body weight, blood glucose level and glycated hemoglobin, improved glucose tolerance, attenuated insulin resistance and hepatic glucogenesis, regulated serum lipid parameters, and increased fatty acid oxidation and mitochondrial functions.</P> <P><B>Conclusion</B></P> <P>Our findings strongly suggest that novel osmotin might be a potential novel therapeutic tool against obesity/diabetes-induced NAFLD and other metabolic disorders.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Osmotin <I>via</I> AdipoRs dependently reduced palmitic acid-induced toxicity <I>in vitro</I>. </LI> <LI> Osmotin regulated AdipoRs/APPL1/PPAR-α/AMPK/SIRT1 pathways in <I>ob/ob</I> and <I>db/db</I> mice. </LI> <LI> Osmotin regulated AdipoRs/APPL1/PPAR-α/AMPK/SIRT1 pathways in HepG2 cells. </LI> <LI> Osmotin regulated the impaired insulin signaling both <I>in vivo</I> and <I>in vitro</I> studies. </LI> <LI> Osmotin treatment regulated plasma chemistry associated with metabolic disorders. </LI> </UL> </P>

Facile and low-temperature synthesis approach to fabricate Sm0.5Sr0.5CoO3−δ cathode material for solid oxide fuel cell

AHMED SHERAZ,카즈미 와자하트 와히드,Hussain Amjad,Khan Muhammad Zubair,Bibi Saira,Saleem Mohsin,송락현,Sajid Zaman,Ullah Abid,Muhammad Kashif Khan 한국세라믹학회 2023 한국세라믹학회지 Vol.60 No.2

Herein, we report a facilely synthesized Sm0.5Sr0.5CoO3 (SSC) nano-catalyst as a cathode material for the solid oxide fuel cell (SOFC). The SSC nano-catalyst was synthesized by a sol–gel process using citric acid and metal nitrates and calcination was performed at a relatively low temperature of 1250 ℃. The crystallinity and morphology of the catalyst were observed by the X-ray diffraction and scanning electron microscope. The average particle size of the SSC powder was 100 nm after calcination at 1250 °C. The resulting SSC material was employed as a cathode for the SOFC. The SOFC cell with highly active SSC showed a peak power density of 900 mWcm−2 at 700 °C. The single cell with an SSC cathode showed excellent stability under the accelerated operating conditions of 0.5A/cm2 and 650 °C for 1250 min. The cell performance was enhanced during the initial hours of the long-term operation which is attributed to the cathode activation process and improved cathode/buffer layer interface contact. This work features a cost-effective, scalable, and reproducible method for the production of highly robust SSC cathode material for the SOFC under relatively low calcination temperatures.