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The Efficacy of Pharmacological Treatment in Pediatric Nonalcoholic Fatty Liver Disease
Taeshik Cho,김용주,백승삼 대한소아소화기영양학회 2012 Pediatric gastroenterology, hepatology & nutrition Vol.15 No.4
Purpose: With growing number of obese children, the prevalence of nonalcoholic fatty liver disease (NAFLD) in pediatric population is increasing. Nonalcoholic steatohepatitis (NASH) is a severe form of NAFLD, and can cause morbid complications. It is important to identify patients in order to grade pathologic severities and treat those children who possibly have NASH. This study was performed to evaluate whether the pharmacological therapy is also effective as well as the body weight reduction in pediatric NAFLD. Methods: Among the 52 children presenting with obesity and hepatopathy, NAFLD was diagnosed through liver biopsy in 29 children, who were 7 to 14 years of age, from January 2006 to December 2011. The patients were advised to reduce their body weight through diverse methods. Medication with Ursodeoxycholic acid (UDCA) and vitamin E was performed in children whose liver functions did not improve or their weight reductions were not successful. The therapeutic effects were monitored and assessed via the biochemical profiles and the physical measurements. Results: The therapy of vitamin E and UDCA combined with body mass index (BMI) reduction showed significantly higher rate of improvement in clinical profiles, which could be seen in data of aspartate aminotransferase (AST), alanine aminotransferase (ALT), AST/ALT ratio, alkaline phosphatase, total bilirubin and γ-glutamyl transpeptidase. Children whose BMI were successfully reduced showed favorable clinical improvements without any medication, but those without BMI reduction did not show any improvement despite medications. Conclusion: This study showed that the first line of therapy should be the BMI reduction in NAFLD and drug therapy combined with BMI reduction could have additive therapeutic effect in children with NAFLD.
A Hybrid Adaptive Security Framework for IEEE 802.15.4-based Wireless Sensor Networks
( Taeshik Shon ),( Yongsuk Park ) 한국인터넷정보학회 2009 KSII Transactions on Internet and Information Syst Vol.3 No.6
With the advent of ubiquitous computing society, many advanced technologies have enabled wireless sensor networks which consist of small sensor nodes. However, the sensor nodes have limited computing resources such as small size memory, low battery life, short transmission range, and low computational capabilities. Thus, decreasing energy consumption is one of the most significant issues in wireless sensor networks. In addition, numerous applications for wireless sensor networks are recently spreading to various fields (health-care, surveillance, location tracking, unmanned monitoring, nuclear reactor control, crop harvesting control, u-city, building automation etc.). For many of them, supporting security functionalities is an indispensable feature. Especially in case wireless sensor networks should provide a sufficient variety of security functions, sensor nodes are required to have more powerful performance and more energy demanding features. In other words, simultaneously providing security features and saving energy faces a trade-off problem. This paper presents a novel energy-efficient security architecture in an IEEE 802.15.4-based wireless sensor network called the Hybrid Adaptive Security (HAS) framework in order to resolve the trade off issue between security and energy. Moreover, we present a performance analysis based on the experimental results and a real implementation model in order to verify the proposed approach.
Computer use at work is associated with self-reported depressive and anxiety disorder
Taeshik Kim,Mo-Yeol Kang,Min-sang Yoo,Dongwook Lee,Yun-Chul Hong 대한직업환경의학회 2016 대한직업환경의학회지 Vol.28 No.-
Background: With the development of technology, extensive use of computers in the workplace is prevalent and increases efficiency. However, computer users are facing new harmful working conditions with high workloads and longer hours. This study aimed to investigate the association between computer use at work and self-reported depressive and anxiety disorder (DAD) in a nationally representative sample of South Korean workers. Methods: This cross-sectional study was based on the third Korean Working Conditions Survey (2011), and 48,850 workers were analyzed. Information about computer use and DAD was obtained from a self-administered questionnaire. We investigated the relation between computer use at work and DAD using logistic regression. Results: The 12-month prevalence of DAD in computer-using workers was 1.46 %. After adjustment for sociodemographic factors, the odds ratio for DAD was higher in workers using computers more than 75 % of their workday (OR 1.69, 95 % CI 1.30−2.20) than in workers using computers less than 50 % of their shift. After stratifying by working hours, computer use for over 75 % of the work time was significantly associated with increased odds of DAD in 20–39, 41–50, 51–60, and over 60 working hours per week. After stratifying by occupation, education, and job status, computer use for more than 75 % of the work time was related with higher odds of DAD in sales and service workers, those with high school and college education, and those who were self-employed and employers. Conclusions: A high proportion of computer use at work may be associated with depressive and anxiety disorder. This finding suggests the necessity of a work guideline to help the workers suffering from high computer use at work.
디바이스 융합 보안을 위한 향상된 RF4CE 키 교환 기법에 관한 연구
손태식(Taeshik Shon),구본현(Bonhyun Koo),한규석(Kyusuk Han) 한국통신학회 2010 韓國通信學會論文誌 Vol.35 No.6b
방송과 통신의 융합으로 시작된 미디어 플랫폼간의 융합은 이제 다양한 컨버전스 서비스를 창출하기 위한 S/W 생태계 구축을 시작으로 IT 및 비IT를 망라하여 전 업종으로 융·복합화를 앞당기고 있다. 이러한 컨버전스 환경의 대두와 함께 가정 및 산업용, 그리고 다양한 환경에서의 기기간 자동화 및 연결을 통한 새로운 부가 서비스를 창출하려는 RF4CE (Radio Frequency for Consumer Electronics) 기술이 대두되고 있으며, 본 논문에서는 기기간 효율적인 연결 및 제어를 위해 활용될 수 있는 ZigBee 표준화 기구의 RF4CE 기술에서의 향상된 키 교환 스킴에 대한 방안을 제시하였다. 제시된 방안은 기기간 상호 인증 및 두 단계의 Key Seed 분배 기법 등으로 구성되어 있으며, 본 논문에서는 제안 방안의 분석 및 실제 구현 및 실험을 통해 그 유용성을 검증하였다. Platform convergence originated from the convergence of broadcast and telecommunication is making rapid progress including IT and not-IT fields in order to provide a variety of converged services, S/W eco-system construction, and so on. With the advent of convergence environment, IEEE 802.15.4-based RF4CE technology is rising because of creating momentum for the market using converged connectivity between home and office devices as well as all around located devices. In this paper, we present enhanced RF4CE key seed distribution approach in order to provide efficient connection and control between devices. The proposed approach consists of device mutual authentication, initial vector assignment, and two-phase key seed distribution. Moreover, we make a development real RF4CE test board and its key agreement simulator to verify the proposed approach.
Cloud Computing에서의 IoT(Internet of Things) 보안 동향
손태식(Taeshik Shon),고종빈(Jongbin Ko) 한국정보보호학회 2012 情報保護學會誌 Vol.22 No.1
클라우드 컴퓨팅과 IoT 기술은 미래 ICT(Information Communication Technologies)의 핵심이 되는 기술이다. 급속한 ICT 기술의 발전과 함께 우리 주변의 모든 사물을 연결하고 주변의 다양한 정보를 습득하는 IoT 인프라에서 발생하는 데이터의 처리와 활용을 위해서도 클라우드 컴퓨팅 환경은 밀접히 고려되어야 할 것이다. 하지만 이러한 두 기술 모두 각각의 보안 취약점이 존재하고, 미래에 두 기술이 병합될 때 추가적인 보안위협이 발생될 수 있다. 본 논문에서는 클라우드 컴퓨팅과 IoT 기술 및 보안 동향에 대해 알아보고 두 기술의 접목 시 발생하게 될 보안 위협요소를 식별하여 이에 대한 대응방안에 대해 검토하여 보고자 한다.