Physical Training Gesture Recognition Using Wristwatch Wearable Devices

Taejune Ahn,Jeawon Park,Jaehyun Choi 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.6

Lately, many companies have launched smart watch products with their own strong points, drawing consumers’ attention. A smart watch has changed our life and made it more convenient, offering some different experiences compared to existing smart phones. More importantly, health care using this device has increasingly been the subject of people’s attention and studies. Most of the existing studies have explored mobile devices and multiple sensors recognizing activities related to the routine such as walking, running, and going up and down the stairs. This study has focused on the use in physical training. We made a wearable device with some features of a smart watch, and studied how to make it recognize the activity the user is performing with the built-in accelometer and gyroscope. It is expected to be helpful for the individuals to manage their own exercise systematically and be practical in the health care industry.

Gradient index lens based combined two-photon microscopy and optical coherence tomography

Wang, Taejun,Li, Qingyun,Xiao, Peng,Ahn, Jinhyo,Kim, Young Eun,Park, Youngrong,Kim, Minjun,Song, Miyeoun,Chung, Euiheon,Chung, Wan Kyun,Ahn, G-One,Kim, Sungjee,Kim, Pilhan,Myung, Seung-Jae,Kim, Ki Hea The Optical Society 2014 Optics express Vol.22 No.11

Lipid Profiles in Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis: A Cross-sectional Analysis

( Sung Soo Ahn ),( Taejun Yoon ),( Jason Jungsik Song ),( Yong-beom Park ),( Sang-won Lee ) 대한류마티스학회 2020 대한류마티스학회지 Vol.27 No.4

Objective. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is an autoimmune disease (AID) characterised by necrotising intravascular inflammation. Growing evidence suggests that immune system triggers altered lipid metabolism in AIDs. We investigated whether changes in lipid profile correlate with severity of disease in AAV. Methods. Seven lipid profiles were evaluated utilizing frozen serum samples from 67 patients registered in the Severance Hospital ANCA-associated VasculitidEs cohort by a chemistry autoanalyzer. The Birmingham Vasculitis Activity Score (BVAS) version 3 was used to measure patient’s assessment of global disease activity. The relationship between the BVAS with continuous variables was calculated by Pearson’s correlation analysis. Results. Thirty-five (52.2%), 19 (28.4%), and 13 (19.4%) patients were diagnosed with microscopic polyangiitis, granulomatosis with polyangiitis, and eosinophilic granulomatosis with polyangiitis, respectively. Patients’ mean age was 60.0 years, and 22 (32.8%) were male. Among the lipid profiles investigated, total cholesterol, high-density lipoprotein, and low-density lipoprotein, and apolipoprotein A1 and B were significantly associated with BVAS; apolipoprotein A1 showed the highest correlation with BVAS (r=-0.521, p<0.001), remaining consistent even in patients with new-onset disease (r=-0.430, p=0.012). Apolipoprotein A1 had the highest association with the renal manifestation score among the clinical scores comprising BVAS (r=-0.457, p<0.001). Conclusion. Decreased lipid levels, especially apolipoprotein A1, are relevant to increased AAV disease activity, and differ according to organ involvement. Measuring lipid profiles could have clinical implications regarding the assessment of global disease activity and organ involvement patterns. (J Rheum Dis 2020;27:261 -269)

3차원 순차적 집적회로에서 계면 포획 전하 밀도 분포와 그 영향

안태준,이시현,유윤섭,Ahn, TaeJun,Lee, Si Hyun,Yu, YunSeop 한국정보통신학회 2015 한국정보통신학회논문지 Vol.19 No.12

3차원 순차적 집적회로에서 열에 의한 손상으로 생성되는 계면 포획 전하가 트랜지스터의 드레인 전류-게이트 전압 특성에 미치는 영향을 소개한다. 2차원 소자 시뮬레이터를 이용해서 산화막 층에 계면 포획 전자 분포를 추출한 결과를 설명한다. 이 계면 포획 전자분포를 고려한 3차원 순차적 집적회로에서 Inter Layer Dielectric (ILD)의 길이에 따른 하층 트랜지스터의 게이트 전압의 변화에 따라서 상층 트랜지스터의 문턱전압 $V_{th}$의 변화량에 대해서 소개한다. 상대적으로 더 늦은 공정인 상층 $HfO_2$층 보다 하층 $HfO_2$층과 양쪽 $SiO_2$층이 열에 의한 영향을 더 많이 받았다. 계면 포획 전하 밀도 분포를 사용하지 않았을 때 보다 사용 했을 때 $V_{th}$ 변화량이 더 적게 변하는 것을 확인 했다. 3차원 순차적 인버터에서 ILD의 길이가 50nm이하로 짧아질수록 점점 더 $V_{th}$ 변화량이 급격히 증가하였다. This paper introduces about the effect on $I_{DS}-V_{GS}$ characteristic of transistor that interface trap charge is created by damage due to heat in a 3D sequential inverter. A interface trap charge distribution in oxide layer in a 3D sequential inverter is extracted using two-dimensional device simulator. The variation of threshold voltage of top transistor according to the gate voltage variation of bottom transistor is also described in terms of Inter Layer Dielectric (ILD) length of 3D sequential inverter, considering the extracted interface trap charge distribution. The extracted interface trap density distribution shows that the bottom $HfO_2$ layer and both the bottom and top $SiO_2$ layer were relatively more affected by heat than the top $HfO_2$ layer with latest process. The threshold voltage variations of the shorter length of ILD in 3D sequential inverter under 50nm is higher than those over 50nm. The $V_{th}$ variation considering the interface trap charge distribution changes less than that excluding it.

Effects of Heavy Metals on Plant Growths and Pigment Contents in Arabidopsis thaliana

Baek, Seung-A,Han, Taejun,Ahn, Soon-Kil,Kang, Hara,Cho, Myung Rae,Lee, Suk-Chan,Im, Kyung-Hoan The Korean Society of Plant Pathology 2012 Plant Pathology Journal Vol.28 No.4

The effect of heavy metals on seedling growth and pigment levels was studied in Arabidopsis using essential (Cu, Mn, and Zn) and non-essential metals (Pb and Hg). Generally increasing the concentrations of the metals resulted in a gradual decrease in root and shoot lengths, a decrease in chlorophylls, an increase in anthocyanins and a fluctuation in carotenoid content depending on the metal types. The toxicity of the metals decreased in the following order: Cu > Hg > Pb > Zn > Mn. Among the five metals, Cu was exceptionally toxic and the most potent inducer of anthocyanins. Pb induced the smallest quantity of anthocyanins but it was the strongest inducer of carotenoids. It suggests that the Cu-stressed Arabidopsis may use anthocyanins as its main antioxidants while the Pb-stressed Arabidopsis use carotenoids as its main protectants. All of the five metals induced an accumulation of anthocyanins. The consistent increase in anthocyanin content in the metal-stressed Arabidpsis indicates that anthocyanins play a major role in the protection against metal stresses.

Toward a Selective, Sensitive, Fast-Responsive, and Biocompatible Two-Photon Probe for Hydrogen Sulfide in Live Cells

Singha, Subhankar,Kim, Dokyoung,Moon, Hyunsoo,Wang, Taejun,Kim, Ki Hean,Shin, Youn Ho,Jung, Junyang,Seo, Eunseok,Lee, Sang-Joon,Ahn, Kyo Han American Chemical Society 2015 ANALYTICAL CHEMISTRY - Vol.87 No.2

<P>Hydrogen sulfide has emerged as an exciting endogenous gasotransmitter in addition to nitric oxide and carbon dioxide. Noninvasive detection methods for hydrogen sulfide thus become indispensable tools for studying its diverse roles in biological systems. Accordingly, fluorescent probes for hydrogen sulfide have received great attention in recent years. A practically useful fluorescent probe for bioimaging of hydrogen sulfide should be selective, sensitive, fast-responsive, biocompatible, observable in the biological optical window, and capable of deep-tissue imaging. These sensing properties, however, are extremely difficult to achieve at the same time. Disclosed here is the two-photon fluorescent probe that meets all of these criteria. The probe belongs to a Michael acceptor system, which raised a serious selectivity issue over the competing biothiols such as cysteine and glutathione. We have addressed the selectivity issue by optimizing the electronic and steric interactions between biothiols and the probe, in addition to achieving very high sensitivity, fast-response, and biocompatibility. Also, the sensing mechanism suggested in the literature was revised. The probe thus enables us to image the endogenously produced hydrogen sulfide with negligible interference from other biothiols in live cells. The excellent sensing properties of the probe combined with its capability of bioimaging thus make it a practically useful tool for further studying biological roles of hydrogen sulfide.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancham/2015/ancham.2015.87.issue-2/ac503806w/production/images/medium/ac-2014-03806w_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ac503806w'>ACS Electronic Supporting Info</A></P>

Atializumab, a humanized anti-aminoacyl-tRNA synthetase-interacting multifunctional protein-1 (AIMP1) antibody significantly improves nephritis in (NZB/NZW) F1 mice

Mun, Chin Hee,Kim, Jin-Ock,Ahn, Sung Soo,Yoon, Taejun,Kim, Su Jeong,Ko, Eunhee,Noh, Hee-Dong,Park, Yong-Beom,Jung, Hak-Jun,Kim, Tae Sung,Lee, Sang-Won,Park, Sang Gyu Elsevier 2019 Biomaterials Vol.220 No.-

<P><B>Abstract</B></P> <P>Aminoacyl-tRNA synthetase (ARS)-interacting multifunctional protein 1 (AIMP1) enhances the expression of proinflammatory cytokines. In our previous study, we have shown that serum AIMP1 in patients with SLE was significantly higher than that of healthy controls. To address whether neutralization of AIMP1 could ameliorate nephritis in lupus-prone mice, we generated atializumab, a humanized antibody against AIMP1 and investigated its therapeutic efficacy. ELISA showed that serum AIMP1 at 23 weeks old was significantly higher than that at 13 weeks old in lupus-prone mice. Therefore, lupus-prone mice were randomly assigned to 5 groups (vehicle, methylprednisolone and 0.5, 2, and 5 mg/kg atializumab). After treatment, disease severity was assessed using a variety of phenotypes, including proteinuria, histological damages, renal deposition of immune-complex. In addition, serum cytokines, anti-dsDNA and IgG subclasses were determined. T cell subsets were analyzed using a fluorescence-activated cell sorter. Atializumab significantly diminished proteinuria, improved glomerular and tubular damages and reduced the renal deposition of immune-complexes. Moreover, atializumab significantly decreased serum interferon (IFN)-γ, interleukin (IL)-17A, and IL-6, whereas it increased serum IL-10. Similarly, atializumab reduced the numbers of T<SUB>H</SUB>1, T<SUB>H</SUB>2 and T<SUB>H</SUB>17 cells in a dose-dependent manner, while atializumab enhanced the number of regulatory T (Treg) cells. Furthermore, atializumab decreased not only splenic plasma cells and serum anti-dsDNA but also pathogenic IgG subclasses for nephritis. It suppressed NF-κB activation by inhibiting IκBα degradation in a dose-dependent manner <I>in vitro</I>. Atializumab alleviated nephritis by inhibiting autoreactive T, B, and plasma cells and decreasing NF-κB-related proinflammatory cytokines in lupus-prone mice. These results suggest that treatment targeting AIMP1 could be a novel and highly immune-modulating therapeutic strategy in lupus nephritis.</P>

터널링 전계효과 트랜지스터 4종류 특성 비교

심언성,안태준,유윤섭,Shim, Un-Seong,Ahn, TaeJun,Yu, YunSeop 한국정보통신학회 2017 한국정보통신학회논문지 Vol.21 No.5

본 연구에서는 TCAD 시뮬레이션을 이용하여 4가지 터널링 전계효과 트랜지스터(Tunnel Field-Effect Transistors; TFETs) 구조에 따른 특성을 조사하였다. 단일게이트 TFET(SG-TFET), 이중게이트 TFET(DG-TFET), L-shaped TFET(L-TFET), Pocket-TFET(P-TFET)의 4가지 TFET를 유전율과 채널 길이를 변화함에 따라서 드레인 전류-게이트전압 특성을 시뮬레이션해서 문턱전압이하 스윙(Subthreshold Swing; SS)과 구동 전류(On-current)면에서 비교하였다. 고유전율을 가지며 라인 터널링을 이용하는 L-TFET 구조와 P-TFET 구조가 포인트 터널링을 이용하는 SG-TFET와 DG-TFET보다 구동전류면에서 10배 이상 증가하였고, SS면에서 20 mV/dec이상 감소하였다. 특히, 고유전율을 가진 P-TFET의 주 전류 메카니즘이 포인트 터널링에서 라인터널링으로 변화하는 험프현상이 사라지면서 SS가 매우 향상되는 것을 보였다. 4가지 TFET 구조의 분석을 통해 포인트터널링을 줄이고 라인터널링을 강조하는 새로운 TFET 구조의 가이드 라인을 제시한다. Using TCAD simulation, performances of tunnel field-effect transistors (TFETs) was investigated. Drain current-gate voltage types of TFET structure such as single-gate TFET (SG-TFET), double-gate TFET (DG-TFET), L-shaped TFET (L-TFET), and Pocket-TFET (P-TFET) are simulated, and then as dielectric constant of gate oxide and channel length are varied their subthreshold swing (SS) and on-current ($I_{on}$) are compared. On-currents and subthreshold swings of the L-TFET and P-TFET structures with high electric constant and line tunneling were 10 times and 20 mV/dec more than those of the SG-TFET and DG-TFET using point tunneling, respectively. Especially, it is shown that hump effect which dominant current element changes from point tunneling to line tunneling, is disappeared in P-TFET with high-k gate oxide such as $HfO_2$. The analysis of 4 types of TFET structure provides guidelines for the design of new types of TFET structure which concentrate on line tunneling by minimizing point tunneling.

ADS-33 평가기준에 따른 소방헬기 비행시뮬레이터의 비행조종성 예비평가

윤석준(Sugjoon Yoon),김동현(Donghyun Kim),성은혜(Eunhye Seong),박태준(Taejun Park),황호연(Hoyon Hwang),안존(Jon Ahn),이정훈(Junghoon Lee) 한국항공우주학회 2016 韓國航空宇宙學會誌 Vol.44 No.9

본 연구는 헬리콥터 비행 시뮬레이터 개발의 첫 번째 단계의 일환으로 비행 운동 모델의 비행조종성을 해석적으로 평가한다. 비행 운동 모델은 시뮬레이터의 목표 항공기인 AS365 N2의 공개 정보를 사용하여 생성하였다. 해당 비행 시뮬레이터는 소방 임무에 대한 조종사 교육 및 연구 도구로 개발 중이다. 모델의 평가는 비행 시험 데이터를 통한 검증이 이루어지기 전에 모델의 비행 특성과 다음 개발 단계로의 적합성을 평가하기 위하여 수행된다. 평가는 항공기분류, 임무 및 환경을 고려하여 ADS-33E-PRF(Aeroautical Design Standard Performance Specification Handling Qualities Requirement)의 기준에 의거하여 수행한다. 항공기의 해석적 비행은 규정에 대한 적합성 평가를 위해 요구되는 혹은 권장되는 비행시험절차를 따른다. 평가 결과는 ADS-33E-PRF에 명시된 조종성 등급에 따라 평가되는데 RotorLibFDM을 기반으로 생성된 비행 운동 모델이 헬기 비행에 대한 기본 교육과 연구로 사용될 수 있는 일반적인 헬리콥터 시뮬레이터에 대한 만족스러운 플랫폼을 제공함이 확인되었다. As a part of the first stage in the helicopter flight simulator development, this study numerically evaluates handling qualities of the dynamics model. The flight dynamics model was generated using public information for AS365 N2, the target aircraft of the simulator. The flight simulator is under development as a pilot training and research tool for firefighting missions. The assessment of the model intends to validate general characteristics and suitability before the model is enhanced with flight test data. The evaluation is based on the ADS-33E-PRF(Aeroautical Design Standard Performance Specification Handling Qualities Requirement) criteria, with consideration of category of the aircraft, missions, and environment. The numerical operations follow required or recommended procedures of flight test for compliance demonstration. Evaluation results are evaluated according to the rating specified in maneuverability ADS-33E-PRF. Results have identified to provide a satisfactory platform for flight dynamic model in the general helicopter simulator generated based on the RotorLibFDM, and can be used as a base for basic training and research.

Millimeter-Scale Growth of Single-Oriented Graphene on a Palladium Silicide Amorphous Film

Kim, Hyun-Woo,Song, Inkyung,Kim, Tae-Hoon,Ahn, Sung Joon,Shin, Ha-Chul,An, Byeong-Seon,Jang, Yamujin,Jeon, Sunam,Kim, Eun Hye,Khadka, Ishwor Bahadur,Gu, TaeJun,Woo, Sun-Hee,Whang, Dongmok,Kim, Youngku American Chemical Society 2019 ACS NANO Vol.13 No.2

<P>It is widely accepted in condensed matter physics and material science communities that a single-oriented overlayer cannot be grown on an amorphous substrate because the disordered substrate randomizes the orientation of the seeds, leading to polycrystalline grains. In the case of two-dimensional materials such as graphene, the large-scale growth of single-oriented materials on an amorphous substrate has remained unsolved. Here, we demonstrate experimentally that the presence of uniformly oriented graphene seeds facilitates the growth of millimeter-scale single-oriented graphene with 3 × 4 mm<SUP>2</SUP> on palladium silicide, which is an amorphous thin film, where the uniformly oriented graphene seeds were epitaxially grown. The amorphous palladium silicide film promotes the growth of the single-oriented growth of graphene by causing carbon atoms to be diffusive and mobile within and on the substrate. In contrast to these results, without the uniformly oriented seeds, the amorphous substrate leads to the growth of polycrystalline graphene grains. This millimeter-scale single-oriented growth from uniformly oriented seeds can be applied to other amorphous substrates.</P> [FIG OMISSION]</BR>