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디지털 화상처리를 이용한 자동차 후부의 하면형상 이 압력분포에 미치는 영향
백태실(Tae-Sil Baek),조기현(Ki-Hyon Cho),백이(Yeeaek),송동영(Dong-Young Song) 한국산업융합학회 2000 한국산업융합학회 논문집 Vol.3 No.1
In order to reduce a aerodynamic drag of the rear, body, effects of rear lower end configurauon of a vehicles were investigated by measuring the pressure distribution,visual flow phenomena by the use of digital image processing technique. The use of flow visualization in recent years has improved the general understanding of structure of complex flow and has yielded valuable information for analyzing fluid flow. As the results, it was found that the shape of rear lower part vehicles not only effected on the pressure distribution of the rear part of the vehicle but also difference of the flow phenomena,<br/> <br/>
Imatinib mesylate in KIT-positive advanced solid tumors excluding gastrointestinal stromal tumor
( Tae Min Kim ),( Sang Il Kim ),( Sook Ryun Park ),( Ji Yeon Baek ),( In Sil Choi ),( Dong Wan Kim ),( Tae You Kim ),( Dae Seog Heo ),( Young Jue Bang ),( Noe Kyeong Kim ) 대한내과학회 2003 대한내과학회 추계학술대회 Vol.65 No.10
Rhizopus oryzae N174를 이용한 액체종국 저장조건에 따른 밀누룩의 품질특성
최정실 ( Jeong Sil Choi ),정석태 ( Seok Tae Jung ),최지호 ( Ji Ho Choi ),최한석 ( Han Seok Choi ),백성열 ( Seong Yeol Baek ),여수환 ( Soo Hwan Yeo ) 한국미생물생명공학회(구 한국산업미생물학회) 2012 한국미생물·생명공학회지 Vol.40 No.4
거미줄곰팡이인 R. oryzae N174를 이용한 액체종국 배양기술을 개발하기 위해, 밀기울 농도별(0, 5, 10, 15 및 20%)로 액체종국을 제조하여 이들의 품질 특성을 조사하였다. 배지에 밀기울 첨가량이 많을수록 균사체량이 많아졌을 뿐 아니라 산도, 아미노산도가 증가하는 특성을 보였다. 또한, 밀기울을 5% 첨가한 군에서 α-amylase와 glucoamylase의 활성도가 높았으며 acidic protease의 경우에는 15% 밀기울 첨가 배지에서 활성도가 높았다. 배양시간 별(0, 24, 48, 72 및 96 hrs) 효소 활성은 48~72시간에 효소활성이 가장 높은 것으로 나타났다. R. oryzae N174 액체종국 최적조건은 5~15% 밀기울 배지에서 48~72시간 배양이 최적조건이었다. 이를 토대로 밀기울 액체종국을 제조하여 저장온도와 저장기간을 달리하여 저장한 후, 밀누룩 제조시 종국으로서 적합한지를 구명하고자 하였다. 제조된 밀누룩의 효소 활성뿐만 아니라 pH, 산도 및 환원당 함량을 비교 분석한 결과, 저장온도와 상관없이 하루 정도 저장한 액체종국을 사용하여 만든 밀누룩에서 높은 수치를 보였다. 저장조건에 따른 형태학적 변화를 살펴본 결과, 저장된 액체종국에서 균사체의 생육과 포자의 생성유무에 따라 밀누룩의 효소 활성에 영향을 미칠 것이라는 예상과는 달리 각 효소의 활성과 균사체의 생장, 포자의 생성과는 큰 차이가 보이지 않았다. Production of liquid starters using wheat bran as a medium for Rhizopus oryzae N174 and the changes in their characteristics noted during storage were investigated in this study. The optimal culture conditions of the liquid starters were determined to be 5~15% (w/v) wheat bran and 48~72 hrs of incubation. The effects of liquid starters with different storage periods and temperatures (-18, 4, 10 and 25oC) on the quality of wheat nuruk were evaluated. According to the results of the pH, acidity, reducing sugar and enzyme activities, it was found that liquid starter using wheat bran preserved for one day, at any temperature, is the best method of storage for seed cultures for R. oryzae N174.
Kim Eun Sil,Yoon Bo Hyun,Lee Seung Min,Choi Min,Kim Eun Hye,Lee Byong-Wook,Kim Sang-Yeob,Pack Chan-Gi,Sung Young Hoon,Baek In-Jeoung,Jung Chang Hee,Kim Tae-Bum,Jeong Jin-Yong,Ha Chang Hoon 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-
Despite the strong influence of the gut microbiota on atherosclerosis, a causal relationship between atherosclerosis pathophysiology and gut microbiota is still unverified. This study was performed to determine the impact of the gut microbiota on the pathogenesis of atherosclerosis caused by genetic deficiency. To elucidate the influence of the gut microbiota on atherosclerosis pathogenesis, an atherosclerosis-prone mouse model (C1q/TNF-related protein 9-knockout (CTRP9-KO) mice) was generated. The gut microbial compositions of CTRP9-KO and WT control mice were compared. Fecal microbiota transplantation (FMT) was performed to confirm the association between gut microbial composition and the progression of atherosclerosis. FMT largely affected the gut microbiota in both CTRP9-KO and WT mice, and all transplanted mice acquired the gut microbiotas of the donor mice. Atherosclerotic lesions in the carotid arteries were decreased in transplanted CTRP9-KO mice compared to CTRP9-KO mice prior to transplantation. Conversely, WT mice transplanted with the gut microbiotas of CTRP9-KO mice showed the opposite effect as that of CTRP9-KO mice transplanted with the gut microbiotas of WT mice. Here, we show that CTRP9 gene deficiency is related to the distribution of the gut microbiota in subjects with atherosclerosis. Transplantation of WT microbiotas into CTRP9-KO mice protected against the progression of atherosclerosis. Conversely, the transplantation of CTRP9-KO microbiotas into WT mice promoted the progression of atherosclerosis. Treating atherosclerosis by restoring gut microbial homeostasis may be an effective therapeutic strategy.