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Atomistic modeling of metallic nanowires in silicon.
Ryu, Hoon,Lee, Sunhee,Weber, Bent,Mahapatra, Suddhasatta,Hollenberg, Lloyd C L,Simmons, Michelle Y,Klimeck, Gerhard RSC Pub 2013 Nanoscale Vol.5 No.18
<P>Scanning tunneling microscope (STM) lithography has recently demonstrated the ultimate in device scaling with buried, conducting nanowires just a few atoms wide and the realization of single atom transistors, where a single P atom has been placed inside a transistor architecture with atomic precision accuracy. Despite the dimensions of the critical parts of these devices being defined by a small number of P atoms, the device electronic properties are influenced by the surrounding 10(4) to 10(6) Si atoms. Such effects are hard to capture with most modeling approaches, and prior to this work no theory existed that could explore the realistic size of the complete device in which both dopant disorder and placement are important. This work presents a comprehensive study of the electronic and transport properties of ultra-thin (<10 nm wide) monolayer highly P δ-doped Si (Si:P) nanowires in a fully atomistic self-consistent tight-binding approach. This atomistic approach covering large device volumes allows for a systematic study of disorder on the physical properties of the nanowires. Excellent quantitative agreement is observed with recent resistance measurements of STM-patterned nanowires [Weber et al., Science, 2012, 335, 64], confirming the presence of metallic behavior at the scaling limit. At high doping densities the channel resistance is shown to be insensitive to the exact channel dopant placement highlighting their future use as metallic interconnects. This work presents the first theoretical study of Si:P nanowires that are realistically extended and disordered, providing a strong theoretical foundation for the design and understanding of atomic-scale electronics.</P>
Effect of Chunbo Ginseng<SUP>®</SUP> Extract on Cyclophosphamide-Induced Teratogenicity in Rats
Sunhee Shin,Ja Young Jang,Yea Eun Lee,Sang Kuk Byun,Byong-il Choi,Jae Myun Ryu,Dongsun Park,Jeong Hee Jeon,Yun-Bae Kim 한국실험동물학회 2006 Laboratory Animal Research Vol.22 No.1
Effects of Chunbo ginseng<SUP>®</SUP> extract on external, visceral and skeletal abnormalities induced by cyclophosphamide were investigated in rats. Pregnant rats were orally administered with Chunbo ginseng<SUP>®</SUP> extract (100 or 500 ㎎/㎏) for 7 days, from days 6 to 12 of gestation, and intraperitoneally exposed to cyclophosphamide (12 ㎎/㎏) 1 hr after the final treatment. On day 20 of gestation, the maternal and fetal abnormalities were examined under Cesarian section. Cyclophosphamide reduced fetal and placental weights without increase in resorption and death, and induced 80% of malformations in live fetuses. The malformations include cranial defect and exencephaly (80.0%), micrognathia and tongue extrusion (20.9%), edema and hematoma (29.1%), ventricular dilatation (16.7%), vertebral defects (78.6%), costal defects (44.6%), and delayed skeletal ossification (80.4%). Chunbo ginseng<SUP>®</SUP> extract further decreased the fetal weights and remarkably enhanced fetal defects in a dose-dependent manner, leading to 87.3% of cranial defect and exencephaly, 60.8% of micrognathia and tongue extrusion, 50.6% of limb defects, 95.7% of vertebral defects, 69.6% of costal defects, and 91.3% of delayed skeletal ossification in rats administered with Chunbo ginseng<SUP>®</SUP> extract followed by cyclophosphamide. It is suggested that repeated pretreatment with Chunbo ginseng<SUP>®</SUP> extract may aggravate body weight loss and malformations of fetuses induced by intrauterine exposure to cyclophosphamide.
Nucleation and growth of a helical nanofilament (B4) liquid-crystal phase confined in nanobowls
Ryu, Seong Ho,Kim, Hanim,Lee, Sunhee,Cha, Yun Jeong,Shin, Tae Joo,Ahn, Hyungju,Korblova, Eva,Walba, David M.,Clark, Noel A.,Lee, Sang Bok,Yoon, Dong Ki The Royal Society of Chemistry 2015 SOFT MATTER Vol.11 No.39
<P>The B4 helical nanofilament (HNF) liquid crystal (LC) phase is a three-dimensional (3D) helical structure composed of 2D smectic layers. Because of the complex shape of the HNF phase, it is difficult to understand the generation mechanism of HNFs in the bulk as well as in the thin-film condition. Here, we directly investigated the nucleation and growth of HNFs in nanobowls. A combination of electron microscopy and X-ray diffraction was used to reveal the transitional surface structures, in which barrel-like structures as well as short HNFs with random handedness were observed, depending on the LC film thickness. These results will be useful in achieving a better understanding of thin film structures of complex chiral structures in soft matter.</P> <P>Graphic Abstract</P><P>We investigated the confined B4, helical nanofilament LC phase in nanobowls as a function of LC film thickness. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c5sm01783a'> </P>
류호열 ( Ryu Hoyeol ),최선희 ( Choi Sunhee ),황은경 ( Hwang Eunkyung ) 글로벌영어교육학회(구 호남영어교육학회) 2019 Studies in English education Vol.24 No.4
The purpose of this study is to investigate English learning motivation of vocational high school students and the factors that affect their motivation. A total of 228 students enrolled in a technical high school in Daegu participated in the study. The participants were all male and spread out over three grades. They answered a questionnaire developed by Taguchi, Magid and Papi based on Dörynei’s L2 motivational self system. The questionnaire consisted of 42 items that were categorized into 10 sub-factors. In addition, a semi-structured interview with one of the English teachers working at the school was conducted. The quantitative data analyses reveal that the participants are motivated to learn English to pass tests or get better jobs while they have positive attitudes toward English culture and cultural products. Interestingly, however, the results of the qualitative data analyses somewhat contradict the quantitative analyses. Discussions and suggestions are made for future research and English education for vocational high school students.
바이오의약품 산업에 필요한 세포주 국제표준화 전략 방안
이선희(Sunhee Lee),한애란(Airan Hahn),정은일(Paul E. Jung),류기현(Ki Hyun Ryu) 표준인증안전학회 2017 표준인증안전학회지 Vol.7 No.1
생물산업시장의 폭발적인 성장과 나고야 의정서 발효로 국제사회에서 생물산업분야 국제표준에 대한 요구가 증대하고있다. 국제표준화기구(ISO)를 중심으로 생물자원은행 운영관리과 생물소재 별 관리, 소재 분석방법 등 생물자원에 관한 국제표준이 제정 되고 있다. 의약품․의료기기 산업계에서 빈번하게 사용되는 세포주 관련 표준을 전 세계시장이 주목하는 가운데 ISO/TC 276에서는 한국에서 제안한 ‘포유류 세포주를 위한 프로세스 요구사항’표준(안)을 한국, 미국, 독일, 영국 등의 전문가들이 주축이 되어 표준으로 제정 중이다. 본 연구에서는 생물산업의 핵심소재를 관리하는 생물소재은행에 초점을 맞춰 ISO의 표준화 방향, 생물소재에 관한 주요 표준 선진국의 표준화 동향을 분석하고 이를 바탕으로 국제사회에서 한국이 표준을 주도하기 위한 생물소재별 관리운영 및 소재분석 방법 등 생물산업분야 국제표준화 전략모델을 제시하고 정부의 정책방향 방안을 마련하였다. With the explosive growth of biotechnology industry and enactment of the Nagoya Protocol, the impetus for standardization in the field of biological industry is stronger than ever. The International Organization for Standardization (ISO) is at the center of these efforts for international standardization. ISO/TC 276 Biotechnology has several on going projects on biobank management, handling bioresources, and related analysis methods. Especially, the standardization of industrially and clinically important resources, like cell lines, has received greater attentions worldwide. Experts of ISO/TC 276/WG 2 are now developing a standard on the process and quality requirements for mammalian cell lines, a project proposed by Korea. This study analyzes the standardization trend in the biobanking field and the current status of standardization in biobanks at the national level. Based on these analyses, we propose a strategic model for the international standardization of biobanks and direction for governmental policies.