Hong JeongHa's Tianyuanshu and Zhengcheng Kaifangfa

홍성사,홍영희,김영욱,Hong, Sung Sa,Hong, Young Hee,Kim, Young Wook The Korean Society for History of Mathematics 2014 Journal for history of mathematics Vol.27 No.3

Tianyuanshu and Zengcheng Kaifangfa introduced in the Song-Yuan dynasties and their contribution to the theory of equations are one of the most important achievements in the history of Chinese mathematics. Furthermore, they became the most fundamental subject in the history of East Asian mathematics as well. The operations, or the mathematical structure of polynomials have been overlooked by traditional mathematics books. Investigation of GuIlJib (九一集) of Joseon mathematician Hong JeongHa reveals that Hong's approach to polynomials is highly structural. For the expansion of $\prod_{k=11}^{n}(x+a_k)$, Hong invented a new method which we name Hong JeongHa's synthetic expansion. Using this, he reveals that the processes in Zhengcheng Kaifangfa is not synthetic division but synthetic expansion.

Lack of Association between Interleukin-1 <i>β</i> Gene Polymorphism (rs16944) and Chronic Periodontitis: From a Case-Control Studies to an Updated Meta-Analysis

Hong, Seoung-Jin,Kang, Sang Wook,Kim, Su Kang,Kim, Young Sik,Ban, Ju Yeon Hindawi 2018 Disease markers Vol.2018 No.-

<P><B>Background</B></P><P> Interleukin-1<I>β</I> (IL-1<I>β</I>) plays an important role as a mediator of various inflammatory responses in chronic periodontitis. Several studies have investigated the potential relationship between IL-1<I>β</I> polymorphism (rs16944) and susceptibility to chronic periodontitis; inflammatory process is involved, but conclusions is still controversial. </P><P><B>Objective</B></P><P> The aim of this study was to determine whether the IL-1<I>β</I> polymorphism (rs16944) is associated with susceptibility to chronic periodontitis. </P><P><B>Material and Methods</B></P><P> For the case-control study, 51 patients with chronic periodontitis and 33 healthy control patients were recruited in the study. Genotyping was conducted by direct sequencing. SNPStats and SPSS 18.0 were used for the analysis of genetic data and to evaluate odds ratios, 95% confidence intervals, and <I>P</I> values; logistic regression models were used. And to perform meta-analysis, studies about IL-1<I>β</I> polymorphism (rs16944) and chronic periodontitis were searched in PubMed, Embase, Google Scholar, and Korean Studies Information Service System (KISS) electronic databases until July 2017. </P><P><B>Results</B></P><P> In our case-control study, no significant relationship was revealed between IL-1<I>β</I> polymorphism (rs16944) and chronic periodontitis (<I>P</I> > 0.05 in each model). When combined with the previous studies in the meta-analysis, the result was not associated with chronic periodontitis in any of the models (CC vs. CT + TT: OR = 0.97, 95% CI = 0.762–1.246; CC + CT vs. TT: OR = 0.90, 95% CI = 0.658–1.232; and C vs. T: OR = 0.93, 95% CI = 0.774–1.128). The subgroup analysis stratified by ethnicity showed a weak association between the IL-1<I>β</I> polymorphism (rs16944) and chronic periodontitis in the Caucasian population (recessive model, OR = 1.34, 95% CI = 1.017–1.758, <I>P</I> = 0.037). </P><P><B>Conclusion</B></P><P> Evidences from a case-control study and the meta-analysis suggest that IL-1<I>β</I> polymorphism (rs16944) is not associated with susceptibility to chronic periodontitis.</P>

Fast Intra Mode Decision Using DCT Coefficient Distribution in H.264/AVC

HONG, Sung-Wook,LEE, Yung-Lyul The Institute of Electronics, Information and Comm 2010 IEICE transactions on fundamentals of electronics, Vol.93 No.3

<P>The rate-distortion optimization (RDO) method in the H.264/AVC encoder is an informative technology that improves the coding efficiency, but increases the computational complexity. In this letter, a fast Intra mode decision algorithm using DCT (Discrete Cosine Transform) coefficients distribution is proposed to reduce the H.264 encoder complexity. The proposed method reduces the encoder complexity on average 63.44%, while the coding efficiency is slightly decreased compared with the H.264/AVC encoder.</P>

Late target lesion revascularization after implantation of sirolimus-eluting stent

Hong, Myeong-Ki,Mintz, Gary S.,Lee, Cheol Whan,Park, Duk-Woo,Lee, Seung-Whan,Kim, Young-Hak,Jung, In-Hyun,Kim, Sang-Hyun,Cheong, Sang-Sig,Kim, Jae-Joong,Park, Seong-Wook,Park, Seung-Jung Wiley Subscription Services, Inc., A Wiley Company 2008 CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS Vol.71 No.3

<P>Objectives: We evaluated the incidence, clinical presentation, and angiographic in-stent restenosis (ISR) pattern of late target lesion revascularization (TLR) after sirolimus-eluting stent (SES) implantation. Background: Late TLR is an unusual finding beyond 6–9 months after bare-metal stent implantation. However, late TLR after SES implantation has not been sufficiently evaluated. Methods: The study population consisted of 804 patients with 1,020 native lesions that were patent at 6-month follow-up angiogram after SES implantation. Results: Late TLR was performed in 18 patients with 18 lesions (1.8%) at 24.1 ± 2.6 months (range; 18–30 months) after SES implantation. Clinical presentation of late TLR patients was silent ischemia in eight patients and recurrent angina in 10 patients, but none had an acute coronary syndrome. Angiographic ISR pattern of late TLR lesions were focal ISR in 12 lesions (67%) and diffuse ISR in six lesions (33%). Serial quantitative coronary angiographic analysis of these lesions showed a minimal lumen diameter of 2.6 ± 0.5 mm immediately after SES implantation, 2.4 ± 0.4 mm at 6-month follow-up and 0.7 ± 0.6 mm at 24-month follow-up (ANOVA P < 0.001). By stepwise multiple logistic regression analysis, the only independent predictor of late TLR was stent length (P < 0.001, OR = 1.040, 95% CI = 1.019–1.061). Conclusions: Late TLR was performed in 1.8% of 1,020 native lesions that were patent at 6-month follow-up angiogram. Clinical presentations of late TLR was either silent ischemia or recurrent angina, but not acute coronary syndrome. Two-thirds of late TLR lesions had a focal angiographic ISR pattern. © 2007 Wiley-Liss, Inc.</P>

CrowdStart: Warming up cold-start items using crowdsourcing

Hong, Dong-Gyun,Lee, Yeon-Chang,Lee, Jongwuk,Kim, Sang-Wook Elsevier 2019 expert systems with applications Vol.138 No.-

<P><B>Abstract</B></P> <P>The cold-start problem is one of the critical challenges in personalized recommender systems. A lot of existing work has been studied to exploit a user-item rating matrix as well as additional information for users/items, <I>e.g.</I>, user profiles, item contents, and social relationships among users. However, because existing work is primarily biased to the auxiliary information for users/items, it is difficult to identify various and reliable item neighbors that are relevant to cold-start items. To alleviate this limitation, we propose a new <I>crowd-enabled</I> framework, called <ce:sans-serif>CrowdStart</ce:sans-serif>, which is an integrated <I>human-machine</I> approach for new item recommendation. The main contributions of the <ce:sans-serif>CrowdStart</ce:sans-serif> framework are two-fold: (1) To find various and reliable item neighbors for new items, we design two-step crowdsourcing tasks that harness not only machine-only algorithms but also the knowledge of crowd workers (including a few experts and a large number of non-expert workers in a crowdsourcing platform). (2) We develop a novel hybrid model to exploit the user-item rating matrix, the content information about items, and the crowd-based item neighbors from human knowledge into new item recommendation. To evaluate the effectiveness of the <ce:sans-serif>CrowdStart</ce:sans-serif> framework, we conduct extensive experiments including both a user study and simulation tests. Through the empirical study, we found that the <ce:sans-serif>CrowdStart</ce:sans-serif> framework provides <I>relevant, diverse, reliable</I>, and <I>explainable</I> crowd-based neighbors for new items and the crowd-based neighbors are meaningful for improving the accuracy of new item recommendation. The datasets and detailed experimental results are available at https://goo.gl/1iXTUE.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A new framework is proposed to adopt crowdsourcing to the cold-start item problem. </LI> <LI> Sophisticated user interfaces for crowdsourcing is designed. </LI> <LI> Human-machine collaboration is used to address the cold-start item problem. </LI> <LI> Real-world evaluation is conducted with about 400 workers on Amazon Mechanical Turk. </LI> <LI> The proposed framework is effective at improving the cold-start item recommendations. </LI> </UL> </P>

HBV : Serial Changes in Serum Alpha-Fetoprotein Levels before and after Entecavir Therapy in Nucleoside-Na?ve Patients with Chronic Hepatitis B

( Sung Wook Yang ),( Jung Wha Chung ),( Sang Soo Lee ),( Sukho Hong ),( Seong Min Chung ),( Eun Sun Jang ),( Jin Wook Kim ),( Sook Hyang Jeong ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1

Background: Serum level of alpha-fetoprotein (AFP) can elevate in patients with chronic hepatitis B (CHB) without evidence of hepatocellular carcinoma. However, the response of AFP levels to oral nucleos(t)ide analog is not elucidated yet. In this study, we retrospectively assessed the prevalence of high serum AFP levels in CHB patients who were treated with entecavir (ETV), and patterns of AFP changes during the entecavir therapy. Methods: A total of 110 CHB patients who started ETV as an initial antiviral therapy were enrolled in this retrospective study. Pre-treatment clinical , biochemical and virologic parameters were evaluated in relation to the serial AFP levels. Results: The mean baseline AFP value was 41.2 ng/dL. Before ETV therapy (range: 1.3-840 ng/dL). Among the 110 patients, fourty-six (41.8%) showed high pre-treatment AFP values (>10 ng/dl). In the high AFP group, Aspartate transaminase (AST), Alkaline phosphatase (ALP), bilirubin, albumin and prothrombin time (PT) were significantly higher compared to normal AFP group (P=0.021, 0.005, 0.000, 0.001 and 0.004, respective). Only baseline albumin level was significant predictor of high AFP level in multivariate logistic regression analysis (P=0.043, HR=0.00). In high AFP group, The cumulative normalization rates of AFP levels were 26.1%, 73.9% and 91.3% at 18, 36 and 72 weeks, respectively. Serum DNA level was significantly correlated to the time to AFP normalization in a Kaplan-Meier analysis (P=0.039). Conclusions: AFP frequently elevates in CHB patients who undergoes oral nucleoside analog therapy, and baseline albumin level was significantly associated with high AFP level. Normalization of AFP is delayed and about 1/3 shows high AFP levels up to 3 years of ETV therapy. Baseline DNA level was associated with delayed AFP normalization after ETV therapy.

Delayed Severe Hemobilia after Endoscopic Biliary Plastic Stent Insertion

Sung Hak Lee,Seung Goun Hong,Kyoung yong Lee,Pyung Kang Park,Sung Du Kim,Mahn Lee,Dong Wook Yu,Man Yong Hong 대한소화기내시경학회 2016 Clinical Endoscopy Vol.49 No.3

Hemobilia is a rare gastrointestinal bleeding, usually caused by injury to the bile duct. Hemobilia after endoscopic retrograde cholangiopancreatography (ERCP) is generally self-limiting and patients will spontaneously recover, but some severe and fatal hemorrhages have been reported. ERCP-related bowel or bile duct perforation should be managed promptly, according to the type of injury and the status of the patient. We recently experienced a case of late-onset severe hemobilia in which the patient recovered after endoscopic biliary stent insertion. The problem was attributable to ERCP-related bile duct perforation during stone removal, approximately 5 weeks prior to the hemorrhagic episode. The removal of the stent was performed 10 days before the onset of hemobilia. The bleeding was successfully treated by two sessions of transarterial coil embolization.

Structural evolution of layered Li_1.2Ni_0.2Mn_0.6O₂ upon electrochemical cycling in a Li rechargeable battery

Hong, Jihyun,Seo, Dong-Hwa,Kim, Sung-Wook,Gwon, Hyeokjo,Oh, Song-Taek,Kang, Kisuk Royal Society of Chemistry 2010 Journal of materials chemistry Vol.20 No.45

<P>Recently Li<SUB>1.2</SUB>Ni<SUB>0.2</SUB>Mn<SUB>0.6</SUB>O<SUB>2</SUB>, one of the most promising cathode candidates for next generation Li rechargeable batteries, has been consistently investigated especially because of its high lithium storage capacity, which exceeds beyond the theoretical capacity based on conventional chemical concepts. Yet the mechanism and the origin of the overcapacity have not been clearly understood. Previous reports on simultaneous oxygen evolution during the first delithiation may only explain the high capacity of the first charge process, and not of the subsequent cycles. In this work, we report a clarified interpretation of the structural evolution of Li<SUB>1.2</SUB>Ni<SUB>0.2</SUB>Mn<SUB>0.6</SUB>O<SUB>2</SUB> upon the electrochemical cycling, which is the key element in understanding its anomalously high capacity, through careful study of electrochemical profiles, <I>ex</I><I>situ</I> X-ray diffraction, HR-TEM, Raman spectroscopy, and first principles calculation. Moreover, we successfully resolved the intermediate states of structural evolution upon electrochemical cycles by intentionally synthesizing sample with large particle size. All observations made through various tools lead to the result that spinel-like cation arrangement and lithium environment are gradually created and locally embedded in layered framework during repeated electrochemical cycling. Moreover, through analyzing the intermediate states of the structural transformation, this gradual structural evolution could explain the mechanism of the continuous development of the electrochemical activity below 3.5 V and over 4.25 V.</P> <P>Graphic Abstract</P><P>The original layered Li<SUB>1.2</SUB>Ni<SUB>0.2</SUB>Mn<SUB>0.6</SUB>O<SUB>2</SUB> evolves to a structure where the spinel-like region is locally embedded in the layered framework during cycling. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c0jm01971b'> </P>

Preparation of In2O3-ZnO (IZO) Thin Film on Glass Substrate for Organic Light Emitting Device (OLED)

Hong, Jeong Soo,Kim, Sang Mo,Park, Sang Joon,Choi, Hyung Wook,Kim, Kyung Hwan Informa UK (TaylorFrancis) 2010 Molecular Crystals and Liquid Crystals Vol.520 No.1

DNA Methylation and Expression Patterns of Key Tissue-specific Genes in Adult Stem Cells and Stomach Tissues

Hong, Seung-Jin,Kang, Moo-Il,Oh, Jung-Hwan,Jung, Yu-Chae,Kim, Young-Ho,Kim, Sung-Ja,Choi, Seung-Hye,Seo, Eun-Joo,Choi, Sang-Wook,Rhyu, Mun-Gan The Korean Academy of Medical Sciences 2009 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.24 No.5

<P>CpG-island margins and non-island-CpG sites round the transcription start sites of CpG-island-positive and -negative genes are methylated to various degrees in a tissue-specific manner. These methylation-variable CpG sites were analyzed to delineate a relationship between the methylation and transcription of the tissue-specific genes. The level of tissue-specific transcription was estimated by counting the number of the total transcripts in the SAGE (serial analysis of gene expression) database. The methylation status of 12 CpG-island margins and 21 non-island CpG sites near the key tissue-specific genes was examined in pluripotent stromal cells obtained from fat and bone marrow samples as well as in lineage-committed cells from marrow bulk, stomach, colon, breast, and thyroid samples. Of the 33 CpG sites examined, 10 non-island-CpG sites, but none of the CpG-island margins were undermethylated concurrent with tissue-specific expression of their nearby genes. The net methylation of the 33 CpG sites and the net amount of non-island-CpG gene transcripts were high in stomach tissues and low in stromal cells. The present findings suggest that the methylation of the non-island-CpG sites is inversely associated with the expression of the nearby genes, and the concert effect of transitional-CpG methylation is linearly associated with the stomach-specific genes lacking CpG-islands.</P>