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      • 당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

        오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

        연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.

      • KCI등재

        경재소 (京在所)와 유향소 (留鄕所)

        이성무 국제비교한국학회 1995 비교한국학 Comparative Korean Studies Vol.1 No.-

        This essay is the study on correlation between "Kyungjae-so (autonomic organ of authoritative grade in Chosun Dynasty) and "Ryuhyang-so" (autonomic organ of non-authoritative grade in Chosun Dynasty).

      • 복합레진 Core와 비귀금속 Coping간 시멘트 결합력의 시간경과에 따른 비교

        李武鍵,成在鉉 慶北大學校 齒科大學 1984 慶北齒大論文集 Vol.1 No.1

        An in vitro study was conducted to compare the bonding strength of cements between non??ecious metal coping and composite resin core. Sixty identical non-precious metal coping and composite resin core were made using a specially designed die. Twenty samples were cemented with zinc phosphate cement, twenty with polycarboxylate cement and twenty with glass ionomer??ment. Samples were divided into 4 groups, each consisting of 5 zinc phosphate cement, 5 p??ycarboxylate cement and 5. glass ionomer cement samples. The samples were then stored at ??℃ in saline for 1 week, 2 weeks, 3 weeks, and 4 weeks. The tensile strength was tested by an Instron type tension with crosshead speed of ??mm/min. Results were as follows. The best cement for bonding between composite resin core and nonpreciousmetal coping w?? the zinc phosphate cement. when the zinc phosphate cement was used for cementation, the bonding strength was increased according to elapsed time. But in polycarboxylate and glass ionomor cement, the bonding strength was not changed according to elapsed time. And in all cases, the remainder of the cement was remained in the casting. A significiant difference of the bonding strength was not observed between polycarboxylate ??d glass ionomer cement.

      • Isolation and Transcriptional Expression of CuZn Superoxide Dismutase from Codonopsis lanceolata

        Lee,Kang,In,Jun-Gyo,Yu,Chang-Yeon,Yun,Song-Joong,Min,Byung-Hoon,Rho,Yeong-Deok,Kim,Moo-Sung,Yang,Deok-Chun 한국자원식물학회 2004 Plant Resources Vol.7 No.3

        To investigate the defense mechanism against the abiotic stress, a cDNA clone encoding a CuZn superoxide dismutase (CuZnSOD) protein was isolated from a cDNA library prepared from tabroot mRNAs of Codonopsis lanceolata. The eDNA, designated ClSODCc, is 799 nucleotides long and has an open reading frame of 459 bp with a deduced amino acid sequence of 152 residues. The deduced amino acid sequence of ClSODCc matched to the previously reported CuZnSODs. Consensus amino acid residues (His-45, -47, -62, -70, -79, -119 and Asp-82) were involved in Cu-, Cu/Zn-, and Zn- binding ligands. The deduced amino acid sequence of ClSODCc showed high homologies (82%-86%) regardless of species. Expression of ClSODCc by oxidative stress was increased up to 1 h after treatment and declined gradually. Much earlier and stronger expression of ClSODCc was observed in the cold stress treatment.

      • 韓國産 자작나무科의 花粉分類學的 硏究

        李相泰,金茂烈 全北大學校 生物學硏究所 1981 生物學硏究年報 Vol.2 No.-

        The pollen grains of the Korean Betulaceae including 15 species and 4 varieties of 5 genera, were examined to describe the taxonomic characters and to find the phylogenetic position of the family and the inter- and intrageneric as well as the inter- and intraspecific relationships. The possession of 3-6-pororate apertures suggested that the Betulaceae is advanced and has been derived rather from the ancestor of the tricolporate Fagaceae than from the ancestor of the tricolpate Hammamelidaceae. Pollen morphology supported the familial division into Section Betuleae and Coryleae, i. e. vestibula are prominently developed in the former while not in the latter In Section Betuleae, because of the characteristic arcus as well as the high number of pores. Alnus was regarded to be more advanced than Betula. In Section Coryleae, Corylus with inconspicuously developed vestibulum was thought to be the most primative in the family as well. The Carpinus pollen with a higher pore number and larger pollen size suggested to be more advanced than the Ostrya pollen. In Alnus, the mean pore number of the hirsuta group (4.28) was significantly higher than that of the japonica group (4.80). In betula, Series Albae had smaller pollen grains (26.03×20.68㎛) than the Costatae (34.60×28.67㎛). In Corylus, the heterophylla group and the sieboldiana group showed the almost identical pollen morphology. In Carpinus, the tschonoskii group possessed 4 of 5 pores, whereas the cordata 3 pores. The Ostrya pollen exhibited a good similarity with that of C. cordata.

      • SHS법에 의한 TiC-Al₂O₃계 세라믹스의 합성 및 소결특성

        이형복,김성수,편무실,최덕배 明知大學校 産業技術硏究所 1991 産業技術硏究所論文集 Vol.10 No.-

        TiC-Al₂O₃ system powders were prepared by the self-propagating high temperature synthesis method from the mixture of metal titanium, carbon and alumina powder, Powder and sintering characterization of TiC-Al₂O₃ system were investigated. TiC-15wt% Al₂O₃ compacts sintered by hoy-pressing under the pressure of 20MPa at 1850 for 90 minutes showed 3-point bending strength of 724Mpa, ?? of ??????, hardness of 2450㎏/㎟ and relative density of 97%. The combustion mode of combustion wave showed steady-state up to 15wt% Al₂O₃, spin above 20wt% Al₂O₃ also combustion velocity was decreased with increasing of Al₂O₃ contents.

      • 조기위암 천공 1예

        이문수,김태윤,김성용,백무준,김창호,조무식 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        An exceedingly rare case of perforated early gastric cancer is reported. A 68-year-old man developed a peritonitis due to perforation of early gastric cancer. Emergency radical operation was performed and followed by uneventful recovery. The histologic examination of the surgical specimen showed early gastric cancer of typeⅢ, composed signet ring cell carcinoma. 5 years of surgery, the patients survived with no evidence of tumor recurrence. The rarity of this complication in early gastric cancer is discussed and the literature reviewed.

      • 수평면 회전식 풍력발전기에 대한 유체역학적 해석

        이상무 동양대학교 2001 동양대학교 논문집 Vol.7 No.1

        This paper discusses the horizontally rotating wind power generator.Quasi static analysis are applied to evaluate its performance.Translational velocity, which varies on the distance from the rotation center, is assumed constant to apply the fluid dynamic lift and drag coefficients.The analysis shows that the horizontally rotating wind power generator is effective in low rotation speed.In high rotation, the reverse torque reduces the total effective torque.It is recommended to give efforts to reduce the reverse torque for the acceptable performance of the horizontally rotatting type generator.

      • 이온교환법에 의한 수은이온의 흡착에 관한 연구

        李承務,崔光鎬 연세대학교 대학원 1980 延世論叢 Vol.16 No.2

        This investigation on the adsorption of Hg (II) to chelating resin in the fixed bed ion exchange column was carried out to obtain the mass transfer coefficient, and showed by the equilibrium experiment in batch system, that this process was approached to an irreversible reaction, in dilute solution ranging from 1.25×10-7 mol/ml to 1×10-6 mol/ml. Under the irreversible liquid film mass transfer model, kLs was subsequently not only independent of both initial concentration of Hg (II) and amounts of resins, but also proportional to the 0.25 power of the velocity, thereby expressed as following equation; kLS= 0.34 U0.25 This study also brought about another worthwhile conclusion that the irreversible liquid-film mass transfer model in adsorption of Hg (II) would be valid by compared with Selke and Dryden's experimental results, using dimensionless analysis between Reynolds number and j-factor.

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