반코마이신 내성 장내구균 분리 환자에서 황색포도알균의 내성

김동욱,신선혜,김혜진,류선,이선희,장철훈,김영대,곽임수 대한감염학회 2004 감염과 화학요법 Vol.36 No.1

목적 : Vancomycin-resistant enterococci (VRE)로부터 S. aureus로의 vacomycin 내성 유전자의 전파는 오래전부터 예견되어져 왔으며 큰 걱정거리로 남아있다. 최근에 vanA 유전자를 가지고 있는 vancomycin-resistant S. aureus 2주가 미국에서 분리되었다. 이 연구의 목적은 VRE를 보균하고 있는 환자들에서 S. aureus 보균양상과 항균제 내성을 알아보는데 그 목적이 있다. 재료 및 방법 : 2001년 1월부터 2001년 12월까지 부산대학교병원에 입원하였던 환자들 중 임상검체에서 VRE가 분리된 환자 7명과 2001년 9월부터 12월까지 외과 중 환자실에 입원하였던 환자들 중 VRE 감시배양을 시행하였던 20명의 환자들을 대상으로 하였다. 환자들은 전비공, 액와부, 회음부, 직장에서 매주 면봉으로 검체를 채취하였다. 선별배지에서 검체를 배양하여 S. aureus를 분리하였고 원판 확산법을 이용하여 methicillin 감수성을 측정하였다. Broth microdilution 법으로 vancomycin MIC를 측정하였다. 결과 : 총 27명에서 73회의 방문과 292회의 배양이 시행되었으며 총 67주의 S. aureus가 분리되었다. 이중 64주(95.5%)가 methicillin 내성이었다. 전비공 MRSA 보균율은 VRE를 보균하고 있었던 환자는 19명 중 11명(58%)에서, VRE를 보균하지 않았던 환자는 8명 중 3명(37.5%)으로 VRE 보균자에서 보균율이 더 높았다. 총 64주의 MRSA의 vancomycin MIC의 분포는 0.5-2㎍/mL였으며 2㎍/mL를 초과하는 균주는 발견되지 않았다. 64주 중 vancomycin MIC가 1㎍/mL인 균주가 54주(84.4%)로 가장 많았으며 2㎍/mL 6주(9.4%), 0.5㎍/mL 4주(6.3%)의 순이었다. 결론 : VRE 환자에서 S. aureus의 보균율은 비보균자 보다 높았으며 분리된 균주들은 대부분 MRSA였다. VRSA 균주는 발견되지 않았다. Background : The transfer of vancomycin resistance from vancomycin-resistant enterococci (VRE) to Staphylococcus aureus has been predicted. The purpose of this study is to determine the prevalence and antibiotics resistance of S. aureus among patients colonized with VRE. Methods : Between January 2001 and December 2001, a prospective study was performed at Pusan National University Hospital on 27 patients. Surveillance swabs from nasal cavity, axilla, perineum, and rectum were obtained at weekly intervals. Methicillin susceptability of S. aureus was determined by oxacillin disk diffusion test and minimum inhibitory concentration (MIC) for vancomycin by microdilution broth test. Results : Total of 292 swab cultures were performed and 67 S. aureus isolates were collected. 64 isolates (95.5%) were resistant to methicillin. The prevalence of nasal MRSA carrier in 19 patients colonized with VRE was higher than that in 8 patients not colonized with VRE (58% vs. 37.5%). In 64 MRSA isolates, MIC (㎍/mL) for vancomycin ranged from 0.5 to 2. No isolates with MIC >2 ㎍/mL were observed. MIC of 1 ㎍/mL was shown (observed) in 54 isolates, 2 ㎍/mL in 6 isolates, and 0.5 ㎍/mL in 4 isolates. Conclusion : The prevalence of S. aureus with colonization of VRE is higher than that without colonization of VRE. Most of S. aureus isolates were resistant to methicillin. VRSA isolates were not observed.

원격 영상 정보 시스템의 개발

김선호,유선국,김용구,박성욱,김성림,김남현 대한의료정보학회 1996 Healthcare Informatics Research Vol.2 No.1

Application of Antioxidant Transgenic Mice

Sun?Uk Kim,Hee-Young Yang,Sun-Hee Ahn,Suhee Kim,Dae?Yeul Yu,Dong?Seok Lee,Tae-Hoon Lee 한국실험동물학회 2014 한국실험동물학회 학술발표대회 논문집 Vol.2014 No.8

Original Article : Geographic difference of epidemiological features of HCV infection in Korea

( Kyung Ah Kim ),( Sook Hyang Jeong ),( Eun Sun Jang ),( Young Seok Kim3 ),( Youn Jae Lee ),( Eun Uk Jung ),( In Hee Kim ),( Sung Bum Cho ),( Mee Kyung Kee ),( Chun Kang ) 대한간학회 2014 Clinical and Molecular Hepatology(대한간학회지) Vol.20 No.4

Background/Aims: The prevalence of hepatitis C virus (HCV) infection in Korea exhibits significant geographic variation, with it being higher in Busan and Jeonam than in other areas. The reason for this intranational geographic difference was investigated in this study by conducting a comparative analysis of the risk factors related to HCV infection among three geographic areas: the capital (Seoul), Busan, and the province of Jeolla. Methods: In total, 990 patients with chronic HCV infection were prospectively enrolled at 5 university hospitals located in Seoul (n=374), Busan (n=264), and Jeolla (n=352). A standardized questionnaire survey on the risk factors for HCV infection was administered to these three groups of patients, and a comparative analysis of the findings was performed. Results: The analysis revealed significant regional differences in exposure to the risk factors of HCV infection. By comparison with patients in Seoul as a control group in the multivariate analysis, patients in Busan had significantly more experience of invasive medical procedures, acupuncture, cosmetic procedures, and multiple sex partners. In contrast, patients in Jeolla were significantly older, and they had a higher prevalence of hepatocellular carcinoma, a lower prevalence of multiple sex partners, and had experienced fewer invasive procedures. Conclusions: There was a significant geographic difference in the exposure to potential risk factors of HCV infection between patients from the three studied regions. This may explain the regional variation of the prevalence of HCV infection in Korea, and should be taken into account when planning strategies for the prevention and management of HCV infection. (Clin Mol Hepatol 2014;20:361-367)

Case Reports : Basal Cell Carcinoma on the Pubic Area: Report of a Case and Review of 19 Korean Cases of BCC from Non-sun-exposed Areas

( Jin Park ),( Yong Sun Cho ),( Ki Hun Song ),( Jong Sun Lee ),( Seok Kweon Yun ),( Han Uk Kim ) 대한피부과학회 2011 Annals of Dermatology Vol.23 No.3

Basal cell carcinoma (BCC) is one of the most commonly diagnosed malignant skin tumors and develops characteristically on sun-exposed areas, such as the head and neck. Ultraviolet light exposure is an important etiologic factor in BCCs, and BCCs arising from non-sun- exposed areas are, therefore, very rare. In particular, the axilla, nipple, the genital and perianal areas are not likely to be exposed to ultraviolet light; thus, if BCC develops in these areas, other predisposing factors should be considered. Herein, we report a case of BCC arising on the pubic area in a 70-year-old man. We also performed a survey of the literature and discussed the 19 cases of BCC from non-sun-exposed areas reported to date in Korea.

遊離窒素 固定 微生物의 分子生物學的 硏究 : Ⅱ. Cross-inoculation test with isolated Rhizobiol strains on Korean varieties of soybean and their N₂-fixing ability Ⅱ. 韓國 大豆品種에 대한 接種性과 窒素 固定能 試驗

金景旻,林善旭 서울大學校 農科大學 1985 서울대농학연구지 Vol.10 No.1

Present study was to examine the affinity of soybean varieties to R. japonicum strains through artificial cross-inoculation test. A pot culture experiment was conducted with 11 varieties of soybean and 9 selected strains of Rhizobium japonicum. The results are summarized as follows: 1. There were differences in nodule number, nodule fresh weight, acetylene reduction activity and plant nitrogen content with R. joponicum inoculation to soybean varieties. 2. The results of 3 selected strains inoculation to 11 soybean varieties showed high nitrogen fixing affinity in Jangyub, Backchun & Kwanggyo in case of S156 strain in Danyub, Kwanggyo & Whanggun in case of S203 strain and in Namchun, Backchun & Bongui in case of S252 strain. 3. The effects of 9 selected strains inoculation to 3 soybean varieties each showed high nodulation and nitrogen fixing ability in S101,S151&S252 strains to soybean Jangback, in S017,S154&S203strains to soybean Hill, and in S101& S104 strains to soybean Jangyub.

SA-ASTM 주사기법에 의한 악취발생량 평가 및 무취공기 표준화에 관한 연구

김선태,배병욱,김학민,임경묵 대전대학교 산업기술연구소 1999 산업기술연구소 論文集 Vol.10 No.1

New methodology to evaluate the complex odor phenomenon was investigated, as called SA-ASTM(Sensor Aided ASTM ) syringe method. Specially we studied on the standardization of non-odorous air which is very important procedure in measuring odorous gas including our SA-ASTM syringe method. We examined the odor sensor value of standard hydrogen sulfide gas and non-odorous air made with ambient and cylinder air. The decision coefficient between H2S concentration and odor sensor value showed 0.992, and correlation formula between olfactory odor degree(Y) and odor sensor value(X) was Y =0.0039log(X) -0.4129. Also, it appeared that it was not appropriate to use ambient air itself because the odor level of ambient air varies with time, site, and situation. Instead we concluded that it was very effective for making the non-odorous air to use the cylinder air with traps which are composed of water, vacant tube, silicagel, charcoal vessels. The analysis results of odor samples by SA-ASTM syringe method using non-odorous air of this study explained the odor threshold and odor intensity well, which is the basic characteristics of odor and necessary data to use the odor dispersion model.

남녀차별금지법(1999~2005)의 여성정책적 의미

김선욱 이화여자대학교 법학연구소 2007 法學論集 Vol.11 No.2

1999년 1월 제정되어 동년 7월부터 시행되었던 "남녀차별금지 및 구제에 관한 법률"(이하 '남녀차별금지법'이라 한다)이 2005년 폐지되었다. 남녀차별금지법은 그 당시 새로 신설된 국가여성정책의 총괄부서인 여성특별위원회가 남녀평등정책의 실현을 위하여 차별사례의 분쟁조정과 처분 등의 준사법적 기능을 보강하여야 한다는 판단 하에 법제정의 노력을 경주하여 얻은 입법적 성과 중의 하나였다. 남녀차별금지법에 의하여 여성특별위원회는 일정한 준사법적 기능을 갖게 되었고, 차별의 철폐는 평등을 촉진해야 하는 여성정책의 기본전제로써 여성정책담당부서인 여성특별위원회가 차별에 대한 준사법적 기능을 갖게 된 것은 매우 중요한 의미를 갖는 것이었다. 그러나 2005년 여성부가 여성가족부가 되면서 업무의 중복들을 이유로 남녀차별금지법에 의한 남녀차별개선위원회의 업무가 국가인원위원회로 넘겨졌고, 기존의 업무 중 성희롱방지교육에 관하여만 여성가족부에 남게 되면서 남녀차별금지법은 폐지되었다. 이에따라 국가인권위원회는 성차별시정업무를 담당하기 위하여 국가인권위원회법을 개정하고 이에 따른 조직을 정비하고 종전의 남녀차별개선위원회의 업무를 이관 받아 수행하고 있다. 또한 국가인권위원회는 정부에 차별금지법 제정을 권고하였고, 이에 따른 논의를 거쳐 최근 법무부는 국가인권위원회와의 오랜 작업 끝에 차별금지법(안)을 입법예고하였다. 차별금지법 제정을 앞두고 그동안의 남녀차별금지법의 여성정책적 의미를 분석해보고 앞으로 제정될 차별금지법의 과제를 생각해보고자 한다. Gender Discrimination Prevention and Relief Act(hereinafter referred to as the “the Act”)was legislated in February 8, 1999, in accordance with the principle of gender equality stated inthe Constitution, to prevent gender discrimination and to realize gender equality in every sector ofsociety by protecting the interests and enforcing the rights of victims. The Act, as law specifying constitutional equal right’s mandate, complete Women’s Development Act to promote gender equality in all the areas by stipulating fundamental rules with regard to the obligation of the State etc. and has the significance as legislative measure to perform CEDAW’s national obligation. It was also notable that the Presidential Commission on Women(hereinafter referred to as the “the Commission”) could exercise quasi-judicial function by the Act. So, in this article I analyzed results of efforts redressing gender discrimination performed by the Commission and examined women-policy’s significance of the Act. While Ministry of Gender Equality was reorganized to Ministry of Gender Equality and Family, the Act was merged with National Human Rights Commission. Therefore, this Act was repealed in April, 2005 two years ago and from June 23, 2005, the National Human Rights Commission has begun to deal with concerning gender discrimination. Thereupon the National Human Rights Commission passed the recommendation proposal on “Anti-Discrimination Law” on July 24, 2006 and advised the Prime Minister to pursue its enactment. Recently, the Ministry of Justice noticed ‘the bill on Anti-Discrimination Law’. Although the Act was repealed, the enactment of Anti-Discrimination Law prohibiting about not only gender discrimination but also all discrimination can be turning point. I hope to make diverse and substantive discrimination-remedy policy and to practice Anti-Discrimination Law within the consciousness in our lives.

현행법상의 여성특별위원회의 기능과 권한의 문제

김선욱 梨花女子大學校 法學硏究所 1998 法學論集 Vol.3 No.1

LabView를 이용한 휴대형 브레이크 저더 측정 소프트웨어 구현

신동욱,김선형 순천향대학교 산업기술연구소 2007 순천향 산업기술연구소논문집 Vol.13 No.2

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