중년여성의 약물사용 실태 조사

이영선,김은경,김경숙,강경인,김희선,신성희,김은숙,최지선,신혜숙,황선기 여성건강간호학회 2001 여성건강간호학회지 Vol.7 No.4

The purpose of this study was to investigate the drug use of middle aged women. The subject consisted of 330 middle aged women who ranged in age from 40 to 60 years. They were selected in Seoul, Kyung-Ki province, Korea. Data were collected by using questionnaires, from April, 10th to 30th 2001 and analyzed by the SPSS PC+ program using qui-square. The results are summarized as follows ; 1. The proportion of drinking and smoking experience was 42.4%, 3.7%. The motivation of drug use was advised family and relatives(46.1%), doctor's order(39.4%), magazine and advertisement(14.5%). Most of middle aged women get the information on knowledge of drug from hospital(47.3%), magazines and advertisement(30.3%), advised family and relatives(22.4%). And 57.9% of the middle aged women didn't know side effect of the using drug and 13.9% of the middle aged women have had experienced with side effect. And the level of attitude on drug abuse in middle aged women was 43%. Most of the subjects(93.9%) didn't use alternative drugs, and they used more than 3 kinds of drugs(47%). 2. They used digestives(44.2%), applying ointments(41.8%), drinks(39.4%), analgesics(39.1%), laxatives(8.8%), anti hypertension drugs (8.8%), and anti-anemic drugs(8.8%) in their orders.

뇌실외 배액술 관리에 대한 이해 및 업무수행 실태

김정숙,윤미선,송소이,이지은,문경선,고지운,임분남,김경희,박경숙 중앙대학교 간호과학연구소 2001 중앙간호논문집 Vol.5 No.2

The objective of this study was to investigate the managing realities of EVD and provide a descriptive survey with the attempt to obtain basic data needed for the standardization of EVD management. For that purpose, 220 questionnaire copies were distributed to those nurses who were working with intensive care units at university hospitals, general hospitals, semi-general hospitals in Seoul, Kyongki-de and local areas. Of 158 returned questionnaire copies, 139 were used for analysis. Data were collected during the term of academic seminars of Neurosurgery Nursing Committee and KICA (Korea Intensive Care Association), ranging from Oct. 26 through 27. 2000. The tools utilized a structured questionnaire form consisting of 21 questions on general characteristics, the level of understanding, the level of work performance, standard management guidelines, etc. The data collected were analysed with frequency, percentage, mean vague, chi -square test using the SPSS 10.0 program Findings were revealed, as follows: For managing the prevention of EVD infection, aseptic technique was found to be of the most importance (48.9%),'the technique should be carried out at an operation room'(92.8%), but it was actually performed at intensive care units (over 51.5%). 'The term of antibiotics use should be less than 7 days' (81.8%), while it was actually executed for less than 7 days (49.5%). 'The proper time of quittance from it should be within less than 7 days'(74.1%) but actual quittance was executed only by 51.1%. 'Set exchange is needed' by 54.0% but actual exchange was implemented merely by 28.1%. 'The subject of management should be nurses' was reflected by 40% but actually 52.0% were carried out. As a result of hating analysed the understanding of the management of EVD by general characteristics, a significant difference was found in the necessity for set exchange by hospitals, in the time of quittance of a catheter, and in ablution items by work experience. The result of hating analysed the work performance levels of EVD management by general characteristics revealed that a significant difference in administration facilities of medicine by the classification of hospitals, especially the use of antibiotics and the quitting time of a catheter by the classification of intensive care units, and in the use of antibiotics and ablution items by the standard management guidelines.

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

主婦들의 貯藏食品 製造 및 具備에 대한 地域間 差異 硏究(Ⅱ)

池宣京 기전여자대학 1993 論文集 Vol.13 No.-

This study was conducted in Seoul and Jeonju from May 20 to July 10, 1991, to determine the regional differences in making and keeping stored food at home. The data used in this study include 416 housewives. Frequency, percentile, mean, student's T-TEST, and oneway ANOVA were used for data analysis. The main results of this study were summarized as follows. (1) The average was 158.8㎝ in height and 56.6㎏ in weight of subjects. Obesity was more in seoul than in Jeonju. Faith of housewives were mainly Buddhism, Christianity and None. In Jeonju Christianity is main faith but in Seoul Buddhism, Sacrificial rite were more performed in Jeonju than in Seoul significantly, Most housewives used processed food for saving times primarily. In Jeonju, there was more differentiation in food distribution between son and daughter. In Seoul number of eating out were significantly higher than in Jeonju. (2) The scores of Sum1 for Seoul were higher than those of Jeonju, and these differences were sifnificant, Because the scores of Sum2, Sum3 and Sum4 for Jeonju were higher than those of Seoul, we found that housewives in Jeonju had made more stored food than in Seoul. (3) There were no regional differences in sausage, boiled fish paste, solen and jjajang, but ramyen, bread, ham, can and curry were more used in Seoul than in Jeonju. Fruits wine, dongdongju, rice cake, rice cookies, bean sprouts, bean curd, buck wheet Jelly, mung bean jelly, dried cereals, yutkireem and frying laver were more made and stored in Jeonju than in Seoul, and these differences were significant. (4) Comparing the three regions-Seoul, Jeonjusi and Jeonbuk-the scores of Sum1 showed some differences between Seoul and Jeonbuk and between Seoul and Jeonjusi, but no differences between Jeonjusi and Jeonbuk. In Sum2, Sum3 and Sum4, there were some differences between Seoul and Jeonjusi, between Seoul and Jeonbuk, and between Jeonjusi and Jeonbuk.

발암원을 투여한 쥐에서 식이지방의 ω6/ω3 비율이 대장의 세포증식에 미치는 영향

지선경 기전여자대학 1997 論文集 Vol.17 No.-

The study was designed to observe the effect of dietary ω6/ω3 fatty acid ratios on colon cell proliferation. Male Sprague-Dawley rats were fed 5 different diets - low ω6/ω3 ratio with fish oil (Low-F) , low ω6/ω3 ratio with perilla oil(Low-P), moderate ratio with perilla oil(Moderate), blend of 10 different commercial fats and oils(High-BL) and high ω6/ω3 ratio(High) - for 8 weeks. Crypt length of proximal and distal colon was the lowest in Low-P group, but this difference was not significant. In both proximal and distal colon crypt circumference was the lowest in Low-P group. Total cell per crypt was lowest in Low-P group in proximal colon and it is significantly different from Low-F, Moderate, High-BL and High groups. In distal colon total cells per crypt was lowest in Low-P group. Blend fat, commonly consumed among Koreans, did not show significant suppressive effect on carcinogenesis because of high ratio(6.7). Thus ω-3 α -linolenic acid rich in low ω6/ω3 ratio could have a protective effect against colon cancer compared to high ω6/ω3 ratio These results suggest that dietary ω6/ ω3 ratio influences colon cell proliferation. Therefore we recommend to use more ω3 fatty acid in food preparation to reduce the risk of colon cancer.

상악동을 침범하는 역위성 유두종의 증례보고

지용화,최보람,허경회,안창현,이삼선 대한구강악안면방사선학회 2009 Imaging Science in Dentistry Vol.39 No.2

The present study reports a case of inverted papilloma of the nasal cavity and infiltrating into the maxillary sinus. Inverted papilloma is an uncommon and locally aggressive benign tumor of the sinonasal region. The patient, 51-year-old male, presented with unilateral nasal obstruction and periodic swelling on the palate without pain. Enhanced CT scan revealed a heterogeneously enhancing solid mass in the nasal cavity and infiltrating into the right maxillary sinus, as well as an incidental, secondarily infected residual cyst m the periapical area of the right maxillary canine. The sinonasal mass was revealed as an inverted papilloma on histopathologic examination.

닭 점막 및 표피조직내의 Transferrin Receptor의 분포에 대한 면역조직화학적 연구

조사선,유영복,이경훈,김지윤,이병란,차중익,백상호 대한해부학회 1996 Anatomy & Cell Biology Vol.29 No.4

主婦들의 貯臟食品 製造 및 具備에 대한 地域間 差異 硏究(Ⅰ)

池宣京 기전여자대학 1991 論文集 Vol.11 No.-

This study was conducted in Seoul and Jeonju from May 20 to July 10, 1991, to determine the regional differences in making and keeping stored food in the home. The data used in this study include 416 housewives. Frequencies, percentiles, mean, Student's T-TEST, Oneway ANOVA and Pearson's correlation were used for data analysis. The results obtained are summarized as follows. (1) The average age for marriage was 23 years old. monthly income of subjects was 600,000∼1,000,000 won and monthly savings were 265,000 won. Of the subject, 76.4% lived in private residences. Also 65.3% lived in single-family house. Furthermore 80.6% belonged to nuclear families. Food expenses were 150,000~200,000 won per month and average family size was 5. This survey showed significant differences in age for marriage, income, the ratio of private residences to multi-family dwellings, experience living with the woman's parents-in-law, number of children, level of education, food expenses and the amount of winter Kimchi between Seoul and Jeonju. (2) The scores of Sum1, Sum2, and Sum3 for Jeonju was higher than those of Seoul, and these differences were significant(P<0.001). Therefore we found that housewives in Jeonju had made more stored food than in Seoul. (3) The correlation between general characteristics-type of dwelling, type of family, experience living with the woman's parents-in-law, wife's employment status, level of education-and scores of Sum1, Sum2 and Sum3 show the following significant result. As age increased, level of education decreased, and age for marriage decreased, the soores of sum1, sum2 and sums gradually increased. Also the women who lived in private residences and who had experience liveing with their parents-in-law showed higher scores of Sum1, Sum2 and Sum3. (4) Most of the housewives made Kimchi, winter Kimchi, Gochujang, Doinjang, Songpyon, Gukganjang themselves. Sometimes they purchase or did not use dried vegetables, Chunggukjang and pickled seafood for Kimchi. Also dried radish cubes, pickled stem of garlic, pickled garlic, salted cucumber and pickled cucumber were used more in Seoul than in Jeonju. (5) Comparing the three regions-Seoul, Jeonju, Jeonbuk-the Score of Sum1 and Sum3 showed some differences between Seoul and Jeonju and between Seoul and Jeonbuk, but no differences between Jeonju and Jeonbuk. In Sum2, there are some differences between Seoul and Jeonju, between Seoul and Jeonbuk, and between Jeonju and Jeonbuk.

Analysis of KAP1 expression patterns and human endogenous retrovirus Env proteins in ovarian cancer

Kyung‑Yoon Jeon,Eun‑Ji Ko,Young Lim Oh,Hongbae Kim,Wan Kyu Eo,김아리,Han Gyu Sun,Meesun Ock,Ki Hyung Kim,Hee‑Jae Cha 한국유전학회 2020 Genes & Genomics Vol.42 No.10

Background Human endogenous retroviruses (HERVs) constitute around 8% of the human genome and have important roles in human health and disease, including cancers. Previous studies showed that HERV envelope (Env) proteins are highly expressed in cancer tissues and co-related with cancer progression. KAP1 has been reported to play a key role in regulating retrotransposons, including HERV-K, through epigenetic silencing. Objective The relationship between KAP-1 and HERV Envs expressions was analyzed only in tumor cell lines and has not yet been studied in cancer tissues. In this study, we analyzed the expression patterns and relationship between KAP1 and HERV Env proteins in ovarian cancer tissues. Method The expression patterns of KAP-1 and HERV Env proteins, including HERV-K and HERV-R, were analyzed in ovarian cancer tissue microarrays that contained 80 surgical specimens, including normal ovary and malignant ovarian cancers. Results The expression of HERV-R Env and KAP1 proteins is signifcantly higher in ovarian cancer compared with normal ovary tissues. However, the expression of HERV-K Env did not change signifcantly in cancer tissues. The expression patterns of HERV-K Env and HERV-R Env signifcantly increased in early stages of cancer and KAP1 expression was higher in certain stage and types of cancers. However, the expression of HERV-K Env, HERV-R Env, and KAP1 did not change in diferent age groups. The correlation between the expression of KAP1 and HERV-Env, including HERV-K and HERV-R, was not signifcantly correlated. Conclusions The results of this study showed that there was no signifcant correlation between the expression of KAP1 and HERV Env proteins in ovarian cancer tissues, unlike studies with cell lines in vitro. These results suggest that the actual expression of HERV Env proteins in ovarian cancer tissues may be regulated through various complex factors as well as KAP1.

복귀돌연변이시험을 이용한 이온화에너지 처리 우유 및 아이스크림의 유전독성학적 평가

유지숙, 한선경, 신명수, 구본철, 최지현, 이주운, 조철훈, 함준상, 이완규 충북대학교 동물의학연구소 2008 Journal of Biomedical and Translational Research Vol.9 No.1

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