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      • KCI등재

        Vancomycin-related Linear IgA Bullous Dermatosis in a Patient with Cervical Cancer

        Lee, Mi Suk,Lee, Byeongmahn,Kim, Dong In,Cho, Kun-Hyung,Cha, Heejeong,Suh, Hoseok 대한감염학회 2005 감염과 화학요법 Vol.37 No.1

        선상 IgA 수포성 피부병(linear IgA bullous dermatosis; LABD)은 기저막대 항원에 대한 IgA 자가항체에 의해 발생하는 질환이다. IgA 자가항체의 생성 기전은 아직 명확하지 않으며 발생 원인에 따라 특발성과 약제 유발성으로 나누며 자가면역 질환, 악성 종양과 연관되어 나타나기도 한다. 저자들은 내원 1년 전 자궁경부암으로 치료받은 후 추적 관찰 중 요추부위 골수염이 의심되어 입원한 48세 여자에서 vancomycin 사용과 관련되어 발생한 LABD 1예를 보고하는 바다. 환자는 척수 골수염의 치료를 위해 vancomycin을 5일째 투여받던 중갑자기 체간부에서 긴장성 수포가 발생하였으며 피부 조직의 직접 면역 형광검사에서 기저막대 층에 선상의 IgA 침착이 있어 LABD로 진단되었다. 본 증례에서 원인 약제인 vancomycin 중단과 스테로이드, dapsone의 병합 사용 후에도 수포 발생이 계속 지속되었는데 기저 질환인 자궁 경부암의 재발 및 인근 척추 전이가 뒤늦게 발견되어 LABD의 유발에 약제뿐만 아니라 자궁 경부암에 의한 종양연관 피부병이 함께 관여한 것으로 사료된다. LABD is an autoimmune subepidermal bullous disease which is characterized by linear deposition of immunoglobulin (Ig) in the basement membrane. The definite pathogenesis of LABD is still unknown. Some cases of LABD have been associated with drugs. Vancomycin is the most commonly implicated drug. Although LABD is a relatively rare adverse reaction of vancomycin, it is important for clinicians to be aware of this reaction because the use of vancomycin is increasing along with the increase in the incidence of MRSA infections.

      • SCIESCOPUSKCI등재

        Thrips Species (Thysanoptera: Thripidae) in Winter Season and Their Vernal Activities on Jeju Island, Korea

        Lee, Gwan-Seok,Lee, Joon-Ho,Kang, Sang-Hun,Woo, Kun-Suk Korean Society of Applied Entomology 2001 Journal of Asia-Pacific Entomology Vol.4 No.2

        Vegetation sampling and sticky trapping were conducted to investigate overwintering thrips species and their vernal activities, respectively, in winter-spring seasons on Jeju island, Korea, from 1994 to 1996. In addition to Thrips palmi Karny, which was reported overwintering on Jeju island by Lee et al. (2001), twelve thrips species belonging to the family Thripidae were found on vegetation during the winter season. Among them, eight species including economically important thrips, Frankliniella intonsa(Trybom), F. occidentalis (Pergande), and T. tabaci Lindeman were found to overwinter on vegetation in the island. Scitothrips dorsalis Hood, however, is uncertatin whether or not it can overwinter on vegetation. Vernal activities of thrips observed by sticky trapping were different among species. All thrips, except for T. palmi, were caught after mid April, and F. intonsa and S. dorsalis were earlier than F. occidentalis and T. tabaci.

      • A Study on the Interior Orientation for Various Image Formation Sensors

        Lee, Suk-Kun,Shin, Sung-Woong Korean Society of Surveying 2004 Korean journal of geomatics Vol.4 No.1

        This study aims to establish interior orientation for various types of sensors including frame cameras, panoramic cameras, line cameras, and whisk-broom scanners. To do so, this study suggests the classification of components of interior orientation of which elements are different according to the sensors. This is entailed by incorporation of sensor characteristics into mathematical models of interior orientation parameters are suggested for being used as guidelines in recovering systematic distortions. Finally, the potential errors resulted from the assumption of regarding sensor model of whisk-broom scanner model as that of push-broom scanner are discussed.

      • The Evaluations of Sensor Models for Push-broom Satellite Sensor

        Lee, Suk-Kun,Chang, Hoon Korean Society of Surveying 2004 Korean journal of geomatics Vol.4 No.1

        The aim of this research is comparing the existing approximation models (e.g. Affine Transformation and Direct Linear Transformation) with Rational Function Model as a substitute of rigorous sensor model of linear array scanner, especially push-broom sensor. To do so, this research investigates the mathematical model of each approximation method. This is followed by the assessments of accuracy of transformation from object space to image space by using simulated data generated by collinearity equations which incorporate or depict the physical aspects of linear array sensor.

      • KCI등재

        Application of Indigenous Benthic Amphipods as Sediment Toxicity Testing Organisms

        Lee, Jung-Suk,Lee, Kyu-Tae,Kim, Dong-Hoon,Kim, Chao-Kook,Lee, Jong-Hyeon,Park, Kun-Ho The Korean Society of Oceanography 2005 Ocean science journal Vol.40 No.1

        A series of experiments were conducted to develop standard test organisms and test protocols for measuring sediment toxicity using candidate amphipods such as Mandibulophoxus mai, Monocorophium acherusicum, Haustorioides indivisus, and Haustorioides koreanus, which are indigenous to Korea. The relevant association of test species with sediment substrates was one of the important factors in sediment bioassay. The indigenous amphipods M mai and M. acherusicum were well associated with test sediments when they were exposed to various sediment substrates from sand to mud. The tolerant limits to various physico-chemical factors affecting bioassay results such as temperature, salinity and ammonia, as well as sensitivities to reference toxicant and contaminated sediments, were investigated using M. mai and M. acherusicum in the present study. These amphipods were tolerant to relatively wide ranges of salinity $(10{\sim}30\;psu)$ and ammonia (<50 ppm), and displayed relevant sensitivity to temperature as well. They are more sensitive to Cd, the reference toxicant, when compared to the standard test species used in other countries. Field-sediment toxicity tests revealed that M. mai would be more sensitive to sediment-associated pollutants than M. acherusicum, while the sensitivity of M. acherusicum was comparable to that of Leptocheirus plumulosus, which has been used as a standard test species in the United States of America. Overall results of this first attempt to develop an amphipod sediment toxicity test protocol in Korea indicated that M. mai and M. acherusicum would be applicable in the toxicity assessment of contaminated sediments, following the further evaluation encompassing various ecological and toxicological studies in addition to test method standardization.

      • Prevalence, Awareness, Treatment, and Control of Hypertension Among People Over 40 Years Old in a Rural Area of South Korea: The Chungju Metabolic Disease Cohort (CMC) Study.

        Lee, Hong-Seok,Park, Yong-Moon,Kwon, Hyuk-Sang,Lee, Jin-Hee,Park, Young Joon,Lim, Sun Young,Lee, Seung-Hwan,Yoon, Kun-Ho,Son, Ho-Young,Kim, Dong Suk,Yim, Hyeon Woo,Lee, Won-Chul Marcel Dekker, Inc 2010 Clinical and experimental hypertension Vol.32 No.3

        <P>The present study was aimed to assess the prevalence, awareness, treatment, control of hypertension, and the related risk factors in a Korean population. A cross-sectional study was conducted in a rural area of South Korea from 2005 to 2006. Subjects (n = 6388) were selected from individuals aged 40 years or older by stratified random cluster sampling. The age-adjusted prevalence of hypertension was 43.8 % (43.1 % in men, 44.9 % in women). The awareness, treatment, and control of hypertension were 60.1%, 91.7%, and 27.2%, respectively. In men, old age (>/= 60 years old) and low waist circumference (< 90 cm) were positively associated with higher awareness and treatment, whereas body mass index (BMI) was negatively associated with blood pressure (BP) control. Women aged 60 years or older were more aware of their condition, more treated, and more in control of their BP as well. In women, high BMI and a family history of diabetes mellitus were positively associated with higher awareness and treatment, whereas low waist circumference (< 80 cm) was negatively associated with BP control. Our findings indicate that appropriate health care should be given to hypertensive subjects on the basis of these risk factors and according to their sex.</P>

      • 공간정보기술에 의한 문화유산의 복원과 생산

        이석배(Suk-Bae Lee),어수창(Su-Chang Auh),이민근(Min-Kun Lee),김영민(Young-Min Kim) 대한공간정보학회 2018 한국공간정보학회 학술대회 Vol.2018 No.5

        4차 산업혁명시대의 핵심은 Cyber Physical System을 통한 Digital Twin의 구축에 있으며. Digital Twin을 정확하게 구축하기 위해서는 UAV, LiDAR, 3D Scanner, MMS, GNSS 등과 같은 공간정보기술들을 필요로 한다. 본 연구에서는 진주성의 촉석루를 대상으로 3D 스캐너에 의한 스캐닝과 3D 모델링을 실시하고 그 결과를 활용하여 2D 도면제작 및 3D 프린팅을 실시하여 문화유산의 복원 및 생산 가능성을 검증하고자 하였다. 연구결과 2D 도면과 3D 모델의 위치정확도는 매우 우수한 것으로 나타났으며, 이에 따라 공간정보기술의 융합에 의한 문화유산 복원 가능성을 충분히 보여주었고, 앞으로 많은 분야에 그 활용성을 기대할 수 있을 것으로 판단된다.

      • SCOPUSKCI등재
      • KCI등재

        IKONOS 컬러 입체영상을 이용한 대규모 도심지역의 3차원 건물복원

        이석군(Lee Suk Kun),박정환(Park Chung Hwan) 대한토목학회 2006 대한토목학회논문집 D Vol.26 No.3D

        본 논문에서는 고해상도 컬러 입체영상을 활용하여 도심지역의 3차원 건물정보를 효율적으로 복원하기 위한 일련의 처리방법을 제안하고자 한다. 본 연구에서 제안된 방법은 BDT 기법을 활용한 건물 추출, Hausdorff 거리와 컬러인덱싱 기법을 활용한 영상정합, 마지막으로 사진측량기법을 활용한 건물복원 등의 3단계의 처리과정을 포함하고 있다. 제안된 알고리즘의 실험은 고해상도 위성영상의 대표격인 IKONOS 컬러 입체영상을 대상으로 수행되었으며, 실험을 통해 건물추출에 있어서 영상의 배경부분과 건물부분의 밝기값의 분산을 증가시키는 BDT 기법이 건물추출에 우수함을 확인할 수 있었다. 또한, 2가지 건물인식기법을 활용한 영상정합 과정에 있어서도 컬러정보와 경계정보를 모두 사용할 경우 대부분의 추출건물들을 자동인식하고 이를 초기위치로 원활한 영상정합이 수행될 수 있음을 확인하였다. 최종적으로 실험지역에 대한 3차원 건물정보는 전방 다항식비례모형을 통해 획득되었으며 기준자료와의 비교를 통해 정확도 분석을 수행하였다. This paper presented an effective strategy to extract the buildings and to reconstruct 3-D buildings using high-resolution multispectral stereo satellite images. Proposed scheme contained three major steps: building enhancement and segmentation using both BDT (Background Discriminant Transformation) and ISODATA algorithm, conjugate building identification using the object matching with Hausdorff distance and color indexing, and 3-D building reconstruction using photogrammetric techniques. IKONOS multispectral stereo images were used to evaluate the scheme. As a result, the BDT technique was verified as an effective tool for enhancing building areas since BDT suppressed the dominance of background to enhance the building as a non-background. In building recognition, color information itself was not enough to identify the conjugate building pairs since most buildings are composed of similar materials such as concrete. When both Hausdorff distance for edge information and color indexing for color information were combined, most segmented buildings in the stereo images were correctly identified. Finally, 3-D building models were successfully generated using the space intersection by the forward RFM (Rational Function Model).

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