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장기 저장연료의 열안정성 및 연료접촉 고무오링의 수명예측 연구
정근우(K. W. Chung),홍진숙(J. S. Hong),김영운(Y. W. Kim),한정식(J. S. Han),정병훈(B. H. Jeong),권태수(T. S. Kwon),서동욱(D. O. Suh),성민준(M. J. Sung),권영일(Y. I. Kwon) 한국트라이볼로지학회 2018 한국윤활학회지(윤활학회지) Vol.34 No.5
Thermal deterioration of fuel due to long-term storage influences engine performance and causes malfunctions. Fuel stability is usually evaluated via heat resistance and thermal stability during a brief heat shock at high temperature; storage stability in this scenario means that there is very little change in the quality of the fuel during long-term storage. In addition, rubber-based products such as oil seals, O-rings, and rubber hoses can influence the quality of the fuel. When these rubber products are in contact with fuel, they can swell, mechanically weaken, and occasionally crack, thus leaking low molar weight rubber and additives including plasticizer and antioxidant into the fuel to degrade its properties and shorten its useful lifetime. This study determines the thermal stabilities of three kinds of synthetic fuels by evaluating their low temperature kinematic viscosities, chemical composition changes via GC analyses, gross heat of combustion, and color changes. We evaluate the compression set of O-rings by immersing one NBR and two FKM rubber O-rings in the three synthetic fuel samples in airtight containers at variable storage temperatures for six months; from this, we estimate the lifetimes of the O-rings using the Power law model. There were very little changes in the chemical compositions and gross heat of combustion after six months of the experiment. The lifetimes are thus dependent on the materials of the rubber products, and in particular, the FKM O-ring was calculated to have a theoretical lifetime of 200 to 5,700 years. These results indicate that the synthetic fuels maintain their physical properties even after long-term storage at high temperatures, and the FKM O-ring is suitable for long-term sealing of these fuels.
Lee, S.K.,Jeannin, O.,Fourmigue, M.,Suh, W.,Noh, D.Y. Elsevier Sequoia 2012 Journal of organometallic chemistry Vol.716 No.-
Platinum(II) aryl thiolate complexes formulated as (P2)Pt(SAr)<SUB>2</SUB> are prepared from the chelating bis(diphenylphosphino)dimethyltetrathiafulvalene (P2), with aryl thiolate ligands (SAr), such as benzenethiolate (BT) and 3,5-dimethylbenzenethiolate (DMBT). The structurally characterized neutral (P2)Pt(SAr)<SUB>2</SUB> complexes afford, upon oxidation with TCNQF<SUB>4</SUB>, dicationic bimetallic Pt(II) complexes formulated as [(P2)Pt(μ-SAr)<SUB>2</SUB>Pt(P2)]<SUP>2+</SUP>, characterized by a flexible {Pt<SUB>2</SUB>(μ-SAr)<SUB>2</SUB>} square motif. The magnetic properties of the TCNQF<SUB>4</SUB><SUP>?-</SUP> salts of these bimetallic Pt(II) complexes are determined from susceptibility measurements and a tentative rationale for the formation of such {Pt<SUB>2</SUB>(μ-SAr)<SUB>2</SUB>} square complexes are provided, based on an original oxidative dimerization process.
Baatartsogt. O,Erdenesuvd. J,Suh S.W,Kim Y.K,Kim Y.Y,Anh K.C,Lim H.K,Choi Kangduk 한국가금학회 2009 한국가금학회 정기총회 및 학술발표회 Vol.26 No.-
Salmonella gallinarum (S. gallinarum) is the causative agent of fowl typhoid, a severe systemic disease of chickens that results in high mortality amongst infected flocks. Due to its virulence, the immune response to S.gallinarum is poorly characterized. The natural resistance-associated macrophage protein 1 (NRAMP1) affects host innate immunity to intracellular bacteria because of its ability to transport divalent cations in late endosome/lysosomes. The objectives of this study were to identify single nucleotide polymorphisms of the NRAMP1 gene in Hy-Line chicks by a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). A PCR-RFLP method was developed to identify a SacI polymorphism for Ser³??. To investigate associations between an NRAMP1 SNP and resistance against S.gallinarum, two NRAMP1 alleles of a T and C were analyzed to 3 genotypes, TT (802 bp), TC (802, 723 bp and 79 bp), and CC (723 and 79 bp). We evaluated the effect of 3 genotypes, such as TT(66 %), CC (36.9 %) and TC (41.9 %) alleles on mortality after S. gallinarum challenge.
Baatartsogt. O,H. K. Lim,Urantulkhuur. B,S. W. Suh,J. D. Kang,B. G. Jang,J. H. Kim,S. H. Kim,J. H. Lee,K. D. Choi 한국가금학회 2007 한국가금학회 정기총회 및 학술발표회 Vol.24 No.-
Fowl typhoi d (FT) i s a severe systemic disease of chickens causing heavy economic losses to the poultry industry through mortality, reduced egg production and culling of precious breeding stocks. It is hard to be discovered by clinical sign, pathology and immunology. The immune response to S. gallinarum is poorly characterized because of its virulence. In this study, the total RNA isolated by spleen lymphocytes for Affymetrix GeneChip and RT-PCR analysis. Total RNA was extracted using TRIzol (Invitrogen, Carlsbad, CA). These results indicate that expression of LY86, FN1, K60, CCL19, ah22 increased and during immune response at chickens B-FVI was decreased in fowl typhoid. In conclusion, the differential expressed genes in spleen lymphocytes from S. gallinarum infected and uninfected control groups were related with immunological defense system of chickens. The several identified gene may be used as valuable in formation for immune response mechanims of FT biology.
Proteomic analysis of Salmonella pullorum infected liver tissue in chicken
Urantulkhuur.B,Baatartsogt.O,H. K. Lim,S.W Suh,Y.Y Kim,C.H Lee,P.K. Mandal,K. D. Choil 한국가금학회 2008 한국가금학회 정기총회 및 학술발표회 Vol.25 No.-
Salmonellosis in poultry is a significant health problem which causes substantial economic loss. One of the common causative agents of chicken salmonellosis is Salmonella pullorum (SP). The goal of this work was to characterize and identify gene expression profiles of chicken liver tissue after infected Salmonella pullorum. In particular, this report focuses on identification of the major proteins that could be identified in Salmonella infected liver. Hundred Hy-Line layer chicks of 10 days old were divided into 5 groups of 20 each. A1, A2, A3 group were infected with high dose(3×10⁹cfu/㎖) of S.P orally and A4, A5 group were kept as non-infected control. One chick was taken randomly from each group after 0, 3, 6, 9, and 12 days and liver was collected. Proteins were separated from 6 days chicks' liver. Two-dimensional electrophoresis was done and mass spectrometry(MS) will identify the protein spots. More than 289 protein spots were detected on silver stained 2DE gels. Three new proteins were found to be expressed in the infected chicken liver. Five proteins were found to have up regulated expression in infected chicken.
Circulating mucosal-associated invariant T cell levels and their cytokine levels in healthy adults
Lee, O.J.,Cho, Y.N.,Kee, S.J.,Kim, M.J.,Jin, H.M.,Lee, S.J.,Park, K.J.,Kim, T.J.,Lee, S.S.,Kwon, Y.S.,Kim, N.,Shin, M.G.,Shin, J.H.,Suh, S.P.,Ryang, D.W.,Park, Y.W. Pergamon Press ; Elsevier Science Ltd 2014 Experimental Gerontology Vol.49 No.-
Mucosal-associated invariant T (MAIT) cells have been reported to play an antimicrobial role in infectious diseases. However, little is known about age- and gender-related changes in circulating MAIT cell level and function in healthy population. The purposes of this study were to examine the level and cytokine production of circulating MAIT cells and their subsets in healthy adults and to investigate potential relationships between clinical parameters and MAIT cell levels or their subset levels. One hundred thirty-three healthy subjects were enrolled in this study. MAIT cells, their subset, and cytokine levels were measured by flow cytometry. Circulating MAIT cell levels were found to vary widely (0.19% to 21.7%) in the study subjects and to be significantly lower in elderly subjects (age, 61-92years) than in young subjects (age, 21-40years) (p<0.0005). No significant difference was found in the circulating MAIT cell levels between male and female subjects. A linear regression analysis revealed that circulating MAIT cell levels declined annually by 3.2% among men and 1.8% among women, respectively. Notably, the proportion of CD4+ MAIT cells increased with age, whereas that of CD8+ MAIT cells decreased with age. In addition, the production of interleukin (IL)-4 by MAIT cells was found to be significantly increased in elderly subjects and the ratio of interferon (IFN)-γ/IL-4 was lower as compared with young subjects, showing a Th1 to Th2 shift in cytokine profile in elderly subjects. Our data suggest that aging is associated with a reduction in circulating MAIT cells, accompanied with alterations in subset composition and cytokine profile.
Noh, J M,Park, W,Suh, C-O,Keum, K C,Kim, Y B,Shin, K H,Kim, K,Chie, E K,Ha, S W,Kim, S S,Ahn, S D,Shin, H S,Kim, J H,Lee, H-S,Lee, N K,Huh, S J,Choi, D H Nature Publishing Group 2014 The British journal of cancer Vol.110 No.6
<P><B>Background:</B></P><P>To evaluate the effects of elective nodal irradiation (ENI) in clinical stage II–III breast cancer patients with pathologically negative lymph nodes (LNs) (ypN0) after neoadjuvant chemotherapy (NAC) followed by breast-conserving surgery (BCS) and radiotherapy (RT).</P><P><B>Methods:</B></P><P>We retrospectively analysed 260 patients with ypN0 who received NAC followed by BCS and RT. Elective nodal irradiation was delivered to 136 (52.3%) patients. The effects of ENI on survival outcomes were evaluated.</P><P><B>Results:</B></P><P>After a median follow-up period of 66.2 months (range, 15.6–127.4 months), 26 patients (10.0%) developed disease recurrence. The 5-year locoregional recurrence-free survival and disease-free survival (DFS) for all patients were 95.5% and 90.5%, respectively. Pathologic T classification (0−is <I>vs</I> 1 <I>vs</I> 2–4) and the number of LNs sampled (<13 <I>vs</I> ⩾13) were associated with DFS (<I>P</I>=0.0086 and 0.0012, respectively). There was no significant difference in survival outcomes according to ENI. Elective nodal irradiation also did not affect survival outcomes in any of the subgroups according to pathologic T classification or the number of LNs sampled.</P><P><B>Conclusions:</B></P><P>ENI may be omitted in patients with ypN0 breast cancer after NAC and BCS. But until the results of the randomised trials are available, patients should be put on these trials.</P>