P247 : A study on use of complementary and alternative medicine for acne

( Sook Kyung Lee ),( Taek Geun Lee ),( Hyun Hwang Bo ),( Tae Gwang Kwon ),( Se Won Jung ),( Young Seok Lee ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

Background: Complementary and alternative medicine (CAM) is any practice that has healing effects, but is not based on evidence demonstrated by scientific method. Recently, CAM has been used in various diseases including acne. However, there have been no studies on CAM for acne in Korea. Objectives: The purpose of this study was to analyze the use of CAM in acne patients. Methods: A total of 159 patients with acne were enrolled on the study, and filled out a questionnaire about use of CAM. Results: Overall 87.4% (139/159) of the patients reported the previous or current use of at least one more type of CAM. Cosmetics for acne (100, 22.9%) was most frequently used, followed by diet therapy (81, 18.5%), spa and bath therapies (77, 17.6%), health food supplement (67, 15.3%), skin care shop (64, 14.6%), oriental medicine (38, 8.7%), and aromatherapy (9, 2.1%). The most common reason for using CAM was ``wish to try everything`` (28.6%), and the most common source of information was internet (40.5%). The therapeutic effect of CAM was best with diet therapy (32.1%). The most common side effect of CAM was aggravation of symptoms. The most common monthly cost for CAM was between 50,000 and 100,000 won/person. Conclusion: As our results, we can predict that the use of various types of CAM for acne will become more common. Therefore, dermatologists need to study about benefits and adverse effects of CAM for acne.

김치 추출물에 의한 Aflatoxin B_1의 돌연변이 억제 효과

황승영,허영미,최영현,이숙희,박건영,이원호 부산대학교 유전공학연구소 1997 분자생물학 연구보 Vol.13 No.-

The inhibitory effects of Kimchi extracts on the mutagenicity induced by aflatoxin B₁(AFB₁) in Salmonella and Drosophila assay systems were studied. The kimchi extracts had inhibitory activity for His^+ to His^+ reverse-mutations induced by AFB₁acting on S. typhimurium TA98. A similar inhibitory effect was detected in somatic cell mutation assaying system of D. melanogaster. In Drosophila wing hair spot test, mutant clone frequency induced by AFB₁was consideranly inhibited by the kimchi extracts. These facts suggest that kimchi rxtracts can inhibit gene mutation, deletion, mititic chromosomal recombination and suppress the formation of cancer and mutation by DNA damage.

밀턴의 마스크에 나타난 자연

황원숙 신영어영문학회 2001 신영어영문학 Vol.18 No.-

In this ecological crisis, the ecocritical criticism is critical to many literary and cultural tradition including the general Christian viewpoint and its attitude toward nature and literary genre like pastoral literature. Pastoral literature has a very long history and it was accepted to Christian monotheistic world though it was born in the Greco-roman, polytheistic world. As the view of nature and the attitude toward it is one of the main themes of the pastoral literature, and those of the Greco-roman age and Christianity are radically different, the pastoral literature of the Christian world may contain conflicting elements in itself. We find that kind of conflict in Milton's pastoral works. Though many of his poems including the two epics contain some elements of pastoral tradition, two masques have pastoral elements as a part of the masque convention. Comus and 'Arcades' have many pastoral elements, which were modified and changed in Milton's world. The modified pastoral elements in these two masques allow them to overcome limitation of the pastoral anti-ecological attitude. Therefore their attitude toward nature in Milton's masques is different from the pastoral nature which solves problems of people with its natural healing power. The real healing power in Milton's masques is from the supernatural beings, like Thyrsis, Genius, and Sabrina. Human beings like the Lady in Comus rely on the guide of these supernatural beings to live safely in the wood, where fallen beings are threatening the good people. The supernatural beings protect good people from the threat of the nature as well. Basically they may justify their possible change and modification of nature for human goodness. Milton denounced the pastoral attitude toward nature, which is not favored by ecocritical point of view. He, however, put nature under the control of the supernatural moral decision, which very much sounds like Christian attitude. Lady's seemingly ecological insistence on 'temperance' should be taken by Thyrsis and Genius in their practice of supernatural power in natural world.

성남시 지역주민의 정신질환에 대한 태도 연구

고영,신수경,황태연,이충순,박연수,김인숙,황은숙,정원재 용인정신의학연구소 1999 용인정신의학보 Vol.6 No.1

Ode on the Morning of Christ's Nativity : Ode on the Birth of a Poet

Won-sook Hwang 한국영미어문학회 2001 영미어문학 Vol.- No.63

The Therapeutic Effect of Tissue Cultured Root of Wild Panax ginseng C.A. Mayer on Spermatogenetic Disorder

Park, Jeong-Sook,Hwang, Seock-Yeon,Lee, Won-Suk,Yu, Kee-Won,Paek, Kee-Yoeup,Hwang, Bang-Yeon,Han, Kun The Pharmaceutical Society of Korea 2006 Archives of Pharmacal Research Vol.29 No.9

This study examined the possibility of using a tissue cultured root of wild Panax ginseng (tcwPG) as a fertility agent. The effect of tcwPG on spermatogenesis was studied using male rats. The tcwPG crude powder was administered orally to 7-week-old rats over a 6-week period. The number of sperm in the testes and epididymides was significantly higher than the control. A histological examination did not reveal any morphological changes in the testes from the tcwPG powder treated rats. Moreover, there were no significant differences in the weights of the heart, spleen, liver, kidney, brain, testes and epididymides. Oligospermia was also induced by administering 2,3,7,8-tetrachlorodaibenzo-p-dioxin (TCDD) to the rats in order to estimate the feasibility of using tcwPG as treatment for infertility caused by spermatogenic disorders. After exposing the rats to TCDD, the tcwPG saponin fraction treated rats showed some improvement in the body weight, sperm number and testis morphology. It was estimated that tcwPG had feasibility as a therapeutic agent on spermatogenic disorder.

EUV-induced surface modification of self-assembled monolayers of furoxans

Han-Na Hwang,Jung Sook Kim,Jung Mu Heo,Hee-seob Kim,Joon Won Park,Kwang-Jin Hwang,Chan-Cuk Hwang 한국진공학회 2009 한국진공학회 학술발표회초록집 Vol.37 No.-

The Effects of Dentifrice Mixed with Green Tea Extract and Cetylpyridinium Chloride in Preventing Gum Diseases and Oral Malodor

Yoo, Su-Min Cho, Ja-Won Hwang, Kyung-Sook Kim, Chan-Ho Chae, Sang-Kun, Sung, Young-Eun Lee, John-Hwa International Journal of Clinical Preventive Denti 2011 International Journal of Clinical Preventive Denti Vol.7 No.1

Objective: The aim of this study was to ascertain the effects on oral environment improvement including the control of dental plaque, the prevention of gingivitis and the repression of oral malodor using dentifrice mixed with hydrated silica, sodium monofluorophosphate, green tea extract and cetylpyridinium chloride. Methods: The experiment was conducted of 95 of Korean male and female adult volunteers using by double blind method. Before the experiment started, the subjects removed their tartar mechanically to make the oral conditions of all subjects same. After 2 weeks for no residual effect, the oral environmental index was measured as baseline value. For 3 months, the subjects were instructed to use dentifrice experimented and the effect of hydrated silica, sodium monofluorophosphate, green tea extract and cetylpyridinium chloride was analyzed comparing experiment group 1 and 2 with control group. Results: The changes of gingivitis and plaque index of 2 experiment groups, which is to figure out the improvement of gingivitis, were significantly different compared to that of control group (p<0.05). Changes of oral malodor of 2 experiment groups were significantly different compared to that of control group (p<0.05). After 3 months freshness of 2experiment groups were significantly different compared to that of control group (p<0.05). The experiment group had freshness at about 7.83, experiment group 1 at about 7.97 while the control group at about 3.15. Conclusion: The most effective improvement especially shown on the oral conditions were dentifrice that contains.

간독성물질들이 아세트아미노펜의 대사와 배설에 미치는 영향

황세진,서경원,박기숙,정태천,김효정 한국응용약물학회 1993 Biomolecules & Therapeutics(구 응용약물학회지) Vol.1 No.1

This study characterized the effect of liver injury produced by hepatotoxicants on the biliary and urinary excretion of acetaminophen(AA) metabolites. Liver damage was produced in male S.-D. rats, 24 hr after dosing with carbon tetrachloride(CCl₄, 0.75 ml/kg, ip) or thioacetamide(TA, 200 ㎎/㎏, ip), or 16 hr after administration of cadmium chloride(CdCl₂, 3.9 ㎎/㎏, iv). Liver damage without renal injury was confirmed by measuring serum enzymes, creatinine and BUN levels as well as by histopathological examination. AA and its metabolites were measured for 3 hr by HPLC in rats injected iv with 1 mmol/kg of AA. The excreted amounts of AA-glucuronide into bile were reduced to 60∼70% of control rats by hepatotoxicants, but did not change urinary excretion of AA-glucuronide and AA-sulfate. Treatments with CCl₄, CdCl₂ and TA decreased the total (biliary plus urinary) excretion of thioethers of AA(30∼50% of control), suggesting that these toxicants decrease cytochrome P-450-mediated toxification of AA. However, treatments of CdCl₂ and TA markedly enhanced the excretion of AA-mercapturate into urine. Thus, CdCl₂ and TA not only influence the formation of AA-glutathione, but may also alter the excretory routes (i.e. bile and urine) for the elimination of AA-metabolite.

Enhancement of Allergen-induced Airway Inflammation by NOX2 Deficiency

Won, Hee-Yeon,Jang, Eun-Jung,Min, Hyun-Jung,Hwang, Eun-Sook The Korean Association of Immunobiologists 2011 Immune Network Vol.11 No.3

Background: NADPH oxidase (NOX) modulates cell proliferation, differentiation and immune response through generation of reactive oxygen species. Particularly, NOX2 is recently reported to be important for regulating Treg cell differentiation of CD4+ T cells. Methods: We employed ovalbumin-induced airway inflammation in wild-type and NOX2-deficient mice and analyzed tissue histopathology and cytokine profiles. Results: We investigated whether NOX2-deficiency affects T cell-mediated airway inflammation. Ovalbumin injection which activates T cell-mediated allergic response increased airway inflammation in wild-type mice, as evidenced by increased immune cell infiltration, allergic cytokine expression, and goblet cell hyperplasia in the lung. Interestingly, NOX2 knockout (KO) mice were more susceptible to allergen-induced lung inflammation compared to wild-type mice. Immune cells including neutrophils, lymphocytes, macrophages, and eosinophils were drastically infiltrated into the lung of NOX2 KO mice and mucus secretion was substantially increased in deficiency of NOX2. Furthermore, inflammatory allergic cytokines and eotaxin were significantly elevated in NOX2 KO mice, in accordance with enhanced generation of inflammatory cytokines interleukin-17 and interferon-${\gamma}$ by CD4+ T cells. Conclusion: These results indicate that NOX2 deficiency favorably produces inflammatory cytokines by T cells and thus increases the susceptibility to severe airway inflammation.