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      • KCI등재후보

        중도장애인의 이전직장복귀 가능성에 관한 연구

        김민섭,송치호 한국장애인고용촉진공단 고용개발원 2007 장애와 고용 Vol.17 No.2

        본 연구는 중도장애인의 이전직장복귀 가능성에 영향을 미치는 요인을 인적자본이론과 차별이론을 중심으로 분석했다. 이를 위해 본 연구는 한국장애인고용촉진공단의‘2005년 장애인근로자 실태조사’데이터를 이용해 근로 중 장애가 발생한 중도장애인을 선별하고 이전직장복귀 여부에 대한 로지스틱 회귀분석을 실시했다. 분석 결과는 다음과 같다. 첫째, 인적자본이론은 중도장애인의 이전직장복귀 가능성을 설명하는 유효한 이론이라는 것이 확인되었다. 인적자본이론의 주요 변수인 교육정도의 경우, 교육기간이 1년 증가하면 이전직장복귀 확률은 평균적으로 0.7% 증가하고, 근속년수가 1년 증가하면 평균적으로 2.3%의 이전 직장복귀 확률이 높아지는 것으로 나타났다. 둘째, 여성장애인은 남성장애인에 비해 이전직장에 복귀할 확률이 평균적으로 6.5% 낮은 것으로 나타나, 중도장애인의 이전직장복귀에도 여성장애인에 대한 이중차별이 존재하는 것으로 분석됐다. 셋째, 장애유형 측면에서는 눈에 쉽게 보이는 신체외부장애인이 장애사실이 부각되지 않는 신체내부장애인보다 이전직장에 복귀할 확률이 낮은 것으로 분석되었다. 이는 장애 발생이후 복귀 여부 결정에 있어 장애에 대한 선입견과 낙인이 작용한다는 의미로서, 장애인의 이전직장복귀 여부를 설명하는 데 차별이론도 일정 정도의 설명력을 가지고 있음을 말해준다. This study analyzes factors determining job retention of the workers with acquired disabilities, focusing on human capital theory and discrimination theory. Using ‘2005 Survey of the Current Status of Workers with Disabilities’ collected by the Korea Employment Promotion Agency for the Disabled(KEPAD), we attempt logistic regression analysis. The model specification in this study has classified the factors that affect job retention probability into three categories; demographic, human capital, disability factor. Based on the pertinent results in the employment of the disabled workers, implications in theory and policy would be induced. The major findings are as follows. First, the human capital theory has been proved to be effective for explaining the job retention probability of the disabled workers. The educational factor, one of the factors based on that theory, has been influenced the job retention. Holding other things the same, as the educational year goes up by one unit, the job retention probability goes up by zero point seven percent on the average. Likewise, as the length of service increases by one unit, the probability increases by two point seven percent on the average, holding the other things constant. Second, holding the level of other things fixed, on average, women’s job retention probability is less than men’s by six point five percent. This result has been implied that the dual discrimination on the women disabled workers still exists in the job retention process of the disabled labor market. Third, one of the disability factors, the disabled type has effected on the job retention probability. Remaining other things the same, the externally corporeal handicapped workers’ job retention probability is lower than the internally corporeal handicapped’s, on the average. This result has suggested that the determinant of the job retention would be affected by the prejudice or stigmatization on the disabled. Consequently, the discrimination theory seems to be effective for elucidating the job retention probability of the disabled workers.

      • 트레드밀 운동시 흡기근 테이핑이 폐활량에 미치는 영향

        김민지,신수영,송월섭,조수진,최동락,황미진,황진규,박진현,김경,Dennis W. Fell 대구대학교 특수교육재활과학연구소 2011 再活科學硏究 Vol.29 No.1

        이 연구는 트레드밀 운동과 키네시오 테이핑의 효과에 따른 폐활량의 변화를 알아보기 위해 26명의 비흡연자가 참가하였으며 키네시오 테이핑을 적용하지 않은 그룹과 키네시오 테이핑을 적용한 두 그룹으로 무작위로 배정하고 각 군들을 주 3회 6주간의 트레드밀 훈련을 실시하였다. 실험 전과 후, 스파이로미터를 사용하여 키네시오 테이핑의 적용 따른 폐활량 변화 효과를 측정하였다. 이 연구의 결과를 종합해보면 키네시오 테이핑을 적용 그룹에서 적용하지 않은 그룹에 비해 FVC, FEV1에서 유의한 증가를 보였다. 이러한 결과는 건강한 성인에서 키네시오 테이핑을 적용한 경우 키네시오 테이핑을 적용하지 않고 트레드밀 운동을 한 경우보다 폐활량의 향상에 효과적이라고 생각되어진다. The purpose of this study was to investigate the variation of vital capacity(VC) according to the effects of kinesio taping with treadmill exercise. Twenty-six non-smokers were participated in this research and these subjects were randomly assigned into two groups. To measure the VC variation effects of kinesio taping, spirometer was used. The collected data were analyzed statistically by using a paired Mauchly test and repeated measure ANOVA. The results of this study were as follows; A group: treadmill with kinesio taping B group: treadmill without kinesio taping. Between A and B, there were significant differences. In the case of A group, there was 11.66% increase of VC, during 3 weeks experiment(p<.01). In the case of B group, there were significant differences, 3.35% increase of VC, during 3 weeks taping intervention(p<.01). After 6 weeks experiment, the improvement of VC shown a significant difference with intergroup (p<.05). From this result, it was revealed that treadmill exercise with kinesio taping was effective to improve VC to healthy adult than treadmill exercise without kinesio taping.

      • Identification of novel tumor suppressors in the DNA damage response pathway and functional validation of them in vivo.

        Song, Min-Seop,Lee, Ho,Lee, Juhyun,Hong, Hyungyoung,Lee, Jinsuk,Shim, Yousun,Song, Sujeong,Lim, Dae-Sik 이화여자대학교 세포신호전달연구센터 2002 고사리 세포신호전달 심포지움 Vol. No.4

        Maintenance of genomic integrity is of fundamental importance for the survival of all living organisms. This genomic integrity can be threatened during normal cell cycling as well as by external chromosomal insults, thus cell must sense the DNA damages and activate the DNA damage signal transduction pathways including cell cycle checkpoint control and DNA repair. The key players in DNA damage responses are the ATM(Ataxia telangiectasia-mutated), ATR(AT and rad3-related), Chk1 and Chk2 kinases in mammalian cells, which play an essential role in activating DNA damage responses via phosphorylation of many downstream targets following DNA damage. The final effectors are checkpoint controller(p53, Nbs1/Mre11/Rad50, Brcal) and DNA repair proteins(NBS1/Mre11/Rad50, Brcal). Significantly, many of genes involved in this pathway are implicated in human cancer prone diseases such as A-T(ATM-/-), Li-Farumeni Syndrome(LF; p53-/- or Chk2-/-); Familial Breast & Ovarian Cancer(Brca+/-), Nijimengen breakage syndrome(NBS1-/-), A-T like disorder(ATLD; Mre11-/-). Since most of proteins mediate their functions through protein-protein interactions, the DNA damage response pathway is a web of protein-protein interactions. Therefore, these genes responsible for developing human cancer prone diseases will provide us to identify more proteins which mutations cause of sporadic cancer development. Here, in order to discover the novel tumor suppressors and to map the protein-protein interactions between known proteins. we developed and used a high-throughput yeast two-hybrid system("reverse proteomics"), starting with 15 proteins involved in the DNA damage responses. First, we mated the prey libraries(4.5×10^(7)) to 15 baits, subsequently the 980 surviving diploid cells in selection media have been identified. Initially, we cloned more than 20 novel genes out of 100 positive clones, which might be involved in DNA damage responses and now continue to analyze the remaining protein-protein interactions. In addition, more than 13 new novel protein-protein interactions were mapped in DNA damage response pathways. We will discuss the partial protein networks and function of novel proteins in DNA damage responses.

      • 증예(症例) : 항결핵제 투여후 발생한 전격성 간염 1예

        송민섭 ( Min Seop Song ),황민호 ( Min Ho Hwang ),윤찬호 ( Chan Ho Yun ),김용문 ( Yong Mun Kim ),김정화 ( Jeoung Hwa Kim ),조덕수 ( Deok Su Cho ),김귀완 ( Kwi Wan Kim ) 전북대학교 의과학연구소 2001 全北醫大論文集 Vol.25 No.1

        항결핵제는 황달을 포함한 전격성 간염에 이르기까지 다양한 정도의 간기능 이상을 초래할 수 있는데 INH, PZA에서 비교적 흔하고 INH와 RFP을 동시에 투여할 때 간독성의 상승효과가 있다. 저자등은 바이러스성 및 자가면역성 간질환이 배제되었고, 다른 독성 물질에 노출된 적이 없었던 4제 병용 투여환자에서 발생한 전격성 간염 1 예를 경험하였기에 문헌고찰과 함께 이를 보고하는 바이다. Idiosyncratic drug reactions may cause fulminant hepatic failure. The most frequent culprits are anaesthetic agents, non-steroidal anti-inflammatory drugs and isoniazid given with rifampicin. In approximately 10 percent of adults treated with the antituberculous drug isoniazid, elevated serum aminotransferase levels develop during the first few weeks of therapy. We report a twenty six year-old male patient with fulminant hepatitis due to antituberculous drugs (isoniazid, rifampicin, ethambutol, pyrazinamide), He, previously having been well, typically develops non-specific symptoms-nausea, malaise and showed jaundice. He suffered from uncontrolled ascites and pleural effusion. Viral hepatitis and alcoholic hepatitis were excluded from his history and serological study data. After changing of antituberculous drugs and with conservative care, he was discharged with improved clinical condition.

      • Growth of FePt nanocrystals by a single bimetallic precursor [(CO)<sub>3</sub>Fe(μ-dppm)(μ-CO)PtCl<sub>2</sub>]

        Song, Hyon Min,Hong, Jung Hoon,Lee, Yong Bok,Kim, Wan Seop,Kim, Youngmee,Kim, Sung-Jin,Hur, Nam Hwi Royal Society of Chemistry 2006 Chemical communications Vol.2006 No.12

        <P>A new single source approach was developed to synthesize face-centered tetragonal (fct) FePt nanoparticles using bimetallic compound (CO)<SUB>3</SUB>Fe(μ-dppm)(μ-CO)PtCl<SUB>2</SUB>, which has been characterized by single crystal X-ray diffraction and was used as the precursor to ensure the accurate stoichiometry of the final FePt product; the ability of the molecular complex to act as a single source precursor for the formation of fct FePt nanocrystals with an average diameter of 3.2 nm has been demonstrated.</P> <P>Graphic Abstract</P><P>Face-centered tetragonal FePt nanoparticles were synthesized from the bimetallic compound (CO)<SUB>3</SUB>Fe(μ-dppm)(μ-CO)PtCl<SUB>2</SUB>. This process represents an important step toward the synthesis of ferromagnetic nanoparticles which serve as a high density magnetic media matrix. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b516831g'> </P>

      • KCI등재

        First Record of Cleantioides planicauda (Crustacea: Isopoda: Holognathidae) from South Korea

        Song, Ji-Hun,Kim, Min-Seop,Min, Gi-Sik The Korean Society of Systematic Zoology 2014 Animal Systematics, Evolution and Diversity Vol.30 No.1

        Cleantioides planicauda (Benedict, 1899) has previously been recorded in China and Japan. In the present study, to our knowledge, we report for the first time the occurrence of this species in South Korea. Here, we provide detailed descriptions and illustrations of the diagnostic characteristics of C. planicauda. Further, for the first time, we determined the partial sequence of mitochondrial cytochrome c oxidase subunit 1 (CO1) gene of C. planicauda for molecular characteristic. Additionally, we provide a key to the Korean species and distribution of the genus Cleantioides. As a result of this study, four species of the genus Cleantioides, including C. planicauda, have now been recorded in South Korea.

      • KCI등재후보

        국내 다기관에서 조사한 지역사회획득 메티실린내성 황색포도알균의 빈도와 임상적 특성

        송진수,최평균,송경호,조재현,김성한,방지환,이창섭,박경화,박경운,신수,최희정,김의석,김동민,이미숙,박완범,김남중,오명돈,김의종,김홍빈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

        목적 : 최근 전세계적으로 지역사회획득 메티실린내성 황색포도알균(community-associated methicillin-resistant Staphylococcus aureus, CA-MRSA)의 보고가 증가하고 있다. 하지만, 우리나라에서는 CA-MRSA 감염증에 대한 증례보고만 있을 뿐 아직까지 체계적인 연구결과가 없는 실정이다. 저자들은 국내에서 CA-MRSA의 빈도, 감염증의 임상적 양상, 분리된 균주의 항균제내성 양상을 조사하였다. 재료 및 방법 : 2005년 1월부터 2005년 6월까지 7개 병원에서 MRSA가 분리된 환자의 명단을 파악한 후 의무기록지와 건강보험심사평가원의 자료를 검토하였다. 외래나 응급실에서 혹은 입원 후 72시간 이내에 균주가 분리되고 MRSA 획득과 관련된 위험인자가 없는 경우 CA-MRSA로 정의하였으며, 분리된 균주의 임상적 의미에 따라 원인병원체(pathogen), 집락화(colonizer), 미결정(undetermined)으로 분류하였다. Penicillin과 oxacillin을 제외하고 3개 이상의 다른 계열 항균제에 내성이면 다제내성으로 정의하였다. 결과 : 연구기간동안 총 3,251주의 황색포도알균이 분리되었으며, 이 중 MRSA는 1,900주(58.4%)였다. MRSA 가운데 CA-MRSA는 114주(6.0%) 였으며, 이들이 분리된 부위는 귀(62주), 비뇨기계(14주), 피부 및 연부조직(11주), 호흡기계(10주), 혈액(3주) 등이었다. CA-MRSA 균주 가운데 집락균은 22주, 원인병원체는 22주였으며, 나머지 균주에 대해서는 그 임상적 의미를 결정할 수 없었다. 항균제 감수성 검사를 시행한 73균주 중 47주(64.4%)는 다제내성이었다. CA-MRSA 감염증 22예 중 피부 및 연부조직 감염(9예)과 중이염/외이도염(9예)이 가장 흔하였다. 침습적 감염증(invasive infection)은 4명(원발성 균혈증 3예, 감염성 관절염 1예)에서 확인되었지만, CA-MRSA 감염증으로 사망한 환자는 없었다. 결론 : 병원내 감염증에서는 MRSA가 심각한 문제이지만, 아직까지 지역사회 감염증에서 CA-MRSA는 흔하지 않았다. Background : Methicillin-resistant Staphylococcus aureus (MRSA) infection has emerged in patients who do not have the established risk factors. In Korea, little is known about the epidemiology and clinical features of community-associated MRSA (CA-MRSA). Material and Methods : Clinical microbiology laboratory databases of 7 hospitals were reviewed to identify the patients from whom MRSA was isolated during the period of January to July 2005. Only one isolate per patient was enrolled. In order to identify the risk factors of MRSA acquisition, the medical records and the Health Insurance Review Agency databases were reviewed. CA-MRSA was defined as MRSA isolated from patient without established risk factors. We analyzed patient demographics, underlying medical conditions, characteristics of infection, and antimicrobial susceptibility profiles. Results : Of total 3,251 S. aureus isolates, 1900 (58.4%) were MRSAs. Of the MRSA isolates, 114 (6.0%) were CA-MRSA. Of 114 CA-MRSA isolates, 22 (19.3%) were colonizers, 22 (19.3%) were pathogens, and the clinical significance of remaining 70 (61.4%) could not be determined. Median age of the 22 patients with CA-MRSA disease was 47 years. Nine patients had skin and soft tissue infections, 9 ear infections, 3 bacteremia, 1 septic arthritis. Seven patients had underlying medical disease. None died of the CA-MRSA infections. Of the 73 isolates of CA-MRSA, 47 (64.4%) were resistant to more than 3 classes of antibiotics besides β-lactams. Conclusion : Although MRSA is highly prevalent among hospital-associated S. aureus infection, CA-MRSA infections are not common.

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