Social Inequities in the Survival of Liver Cancer: A Nationwide Cohort Study in Korea, 2007–2017

Son Mia,Kim Hye-Ri,Choe Seung-Ah,Song Seo-Young,Lim Kyu-Hyoung,Ki Myung,Heo Yeon Jeong,Choi Minseo,Go Seok-Ho,Paek Domyung 대한의학회 2024 Journal of Korean medical science Vol.39 No.12

Background: To analyze the effects of socioeconomic status (type of insurance and income level) and cancer stage on the survival of patients with liver cancer in Korea. Methods: A retrospective cohort study was constructed using data from the Healthcare Big Data Platform project in Korea between January 1, 2007, and December 31, 2017. A total of 143,511 patients in Korea diagnosed with liver cancer (International Classification of Diseases, 10th Revision [ICD-10] codes C22, C220, and C221) were followed for an average of 11 years. Of these, 110,443 died. The patient’s insurance type and income level were used as indicators of socioeconomic status. Unadjusted and adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using a Cox proportional hazards regression model to analyze the relationship between the effects of sex, age, and cancer stage at first diagnosis (Surveillance, Epidemiology, and the End Results; SEER), type of insurance, and income level on the survival of patients with liver cancer. The interactive effects of the type of insurance, income level, and cancer stage on liver cancer death were also analyzed. Results: The lowest income group (medical aid) showed a higher risk for mortality (HR (95% CI); 1.37 (1.27–1.47) for all patients, 1.44 (1.32–1.57) for men, and 1.16 (1.01–1.34) for women) compared to the highest income group (1–6) among liver cancer (ICD-10 code C22) patients. The risk of liver cancer death was also higher in the lowest income group with a distant cancer stage (SEER = 7) diagnosis than for any other group. Conclusion: Liver cancer patients with lower socioeconomic status and more severe cancer stages were at greater risk of death. Reducing social inequalities is needed to improve mortality rates among patients in lower social class groups who present with advanced cancer.

한국 요양보호사 산업재해의 연도별 변화추이

손미아 ( Mia Son ),전거송 ( Geo-song Jeon ),배동철 ( Dong-chul Bae ),손병창 ( Byungchang Son ),김태운 ( Taeun Kim ),윤재원 ( Jae-won Yun ) 한국산업보건학회 (구 한국산업위생학회) 2021 한국산업보건학회지 Vol.31 No.2

Objectives: To investigate the trends of industrial injuries among long-term health care workers in Korea Methods: T7866 injuries were selected from the total industrial injuries approved by the Industrial Accident Compensation Insurance Act(Occupational Safety and Health Act) among long-term health care workers between 2007 and 2016 in Korea. We analyzied the trends of industrial injuries according to work process, occurrence type, and causes. Results: The industrial injuries among long-term health care workers increased since 2012. The mostly occurred area for industrial injuries were low back areas, which is related that the most serious industrial injuries occurred when the one long-term healthcare worker lift manually the recipient, from bed(ondol, Korean floor heating system) to a wheelchair, bed to bath bed, and wheelchair to bath chair. In addition to this, lack of workforce, increased work intensity due to overwork contributed the increasing of occupational injury. Conclusions: This study suggests that the main causes of industrial injuries were Lack of facilities and equipment for small private long-term care institutions, The physical load that goes into lifting the recipient directly, work intensity such as excessive workload and increased work speed. We suggest that the social publicization of long-term care service for the elderly, avoiding ways to lift recipients directly, introducing lifting machines as well as improving working methods, and reducing the workload of caregivers are required.

Sediment에서의 전기활성 박테리아 분포 특성

손형식(Hyeng Sik Son),손희종(Hee Jong Son),김미아(Mia Kim),이상준(Sang Joon Lee) 大韓環境工學會 2010 대한환경공학회지 Vol.32 No.12

낙동강, 회동 및 기장에서 채집한 sediment의 미생물 군집을 FISH 분석을 통하여 조사한 결과, α 그룹, Acidobacter 그룹 및 Cyanobacter 그룹의 분포비율이 가장 높았으며 전체적으로 서로 유사한 분포 특성을 나타내었다. 각각의 sediment를 접종한 MFC 농화배양 이후의 coulombic yield는 낙동강, 회동 및 기장의 경우 각각 0.64 C, 0.50 C, 0.61 C로 나타났으며, 농화배양 완료 후의 미생물 군집분포는 β-Proteobacteria, γ-Proteobacteria, Acidobacter 그룹 및 Firmicutes 그룹이 농화배양 전보다 각각 45~90%, 50~90%, 40~80% 및 45~125% 정도 생체량이 증가한 것으로 나타났다. 농화배양이 끝난 후 16S rDNA를 이용한 미생물 동정결과에서, 낙동강 sediment를 주입한 MFC의 경우는 α-Proteobacteria의 속하는 Roseomonas sp., Azospillum sp.와 γ-Proteobacteria의 Frateuria sp., Dyella sp., Enterobacter sp.와 Deinococci 그룹의 Deinococcus sp.가 동정되었고, 기장 sediment는 α-Proteobacteria의 Azospillum sp.와 β-Proteobacteria의 Delftia sp., Ralstonia sp.와 γ-Proteobacteria의 Klebsiella sp.와 Deinococci 그룹의 Deinococcus sp.가 동정되었으며, 회동 sediment는 γ-Proteobacteria의 Pseudomonas sp., Klebsiella sp.와 Deinococci 그룹의 Deinococci sp.와 Actinobacteria 그룹의 Leifsonia sp.와 Bacilli 그룹의 Bacillus sp.가 동정되었다. Microbial fuel cells (MFC) were enriched using sediment Nakdong river, Hoidong river and protected water area in Gijang. The microbial community of sediment and enriched MFC was analyzed by FISH (fluorescent in situ hybridization) and 16S rDNA sequencing. α-Proteobacteria, Acidobacter and Cyanobactia group were dominant in sediment by FISH. The coulombs of the final 10 peak of the 3 MFC (Nakdong, Hoidong, Gijang) were 0.64 C, 0.50 C, 0.61 C, respectively. When MFCs were enriched by sediment, β-, γ-Proteobacteria, Acidobacter and Firmicutes group increased 45~90%, 50~90%, 40~80% and 45~125%, respectively. In results of 16S rDNA sequencing, Roseomonas sp., Azospillium sp., Frateuria sp., Dyella sp., Enterobacter sp. and Deinocossus were isolated from Nakdong river and Azospillium sp., Delftia sp., Ralstonia sp., Klebsiella sp. and Deinococcus sp. were isolated from protected water area in Gijang and Pseudomonas sp., Klebsiella sp., Deinococcus sp., Leifsonia sp. and Bacillus sp. were isolated from Hoidong river.

활성슬러지내의 전기화학적활성 박테리아 분포 특성

손형식(Hyeng-Sik Son),손희종(Hee-Jong Son),김미아(Mia Kim),이상준(Sang-Joon Lee) 한국생물공학회 2011 KSBB Journal Vol.26 No.5

Microbial fuel cell (MFC) wes enriched using sludge in wastewater treatment. The microbial community of activated sludge and enriched MFC were analyzed by FISH (fluorescent in situ hybridization) and 16S rDNA sequencing. Bacteroidetes group were pre-dominant in activated sludge by FISH. α group, γ group and Acintobacter group were dominant and they were similar to distribution. The average value of 10 peak of MFC is 0.44C. When MFC wase enriched by sludge, γ-Proteobacteria, Plantomycetes group increased 70% and 60%, respectively. In results of 16S rDNA sequencing, Sphiringomonas sp. was comprised in α proteobacteria and Enterobacter sp., Klebsiella sp., Acinetobacter sp., Bacillus sp. were comprised in γ proteobacteria and Chryseobacterium sp. was comprised in Flavobacteria were isolated from sludge.

한 자동차공장에서 연속 12시간 주야 2교대 근무 노동자들의 노동시간 및 노동강도와 수면장해의 연관성

손미아 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.1

결국 이 연구결과는 자동차공장 노동자들에서 교대근무형태의 차이, 즉 주간고정과 주야맞교대의 차이에 의한 장시간의 노동시간 및 야간노동시간의 변화와 수면의 질과 양의 변화를 가져와 근무직후에 심한졸리움을 유발했을것으로 보고 있다. 이 연구의 결과는 교대제의 해결방법은 장시간의 야간 노동시간을 가능한 없애는 것이며, 절대적 노동일(시간)과 노동강도를 줄여나가는 일이다. Background: The object of this study is to explore the relationships of working hours and work intensity with sleep disturbance among 12-hour shift workers in automobile factory in Korea. Method: A questionnaire and a sleep diary were distributed among 2200 (25% of total workers)and 300 workers who were randomly selected, 262 workers in one car factory. Among the 300 randomely selected workers, who were randomly selected, 262 workers filled out a sleep diary. For a questionnaire, 2200 (25%) among 8700 workers were randomly selected, 1200 (54% response rate) of whom filled out the questionnaire. The cross-sectional questionnaire and the sleep diary during 14 consecutive days were distributed and collected by workers' representatives, who were trained for participatory action research in this study. One hundred and sixty worker and used for the analysis in this study. Logistic regression analysis for repeated measurements was modeled using the prevalence of severe sleepiness at work (i.e. Karonlinska Sleepiness Scale 7 or higher) as dependent variable and working hours, sleep pattern, work intensity and health behaviours as independent variables. Results: The prevalence of severe sleepiness at the end of work was more than 60% after finishing night shift in the automobile factory. The main risk factors related to the severe sleepiness at the end of work were the night shift, long working hours more than 10 hours, the higher frequency of night shift per month, less free time between shifts, poor quality of sleep, deficit of sleeping hours and intensified work (reducing tendency of rest time per day and increasing tendency of additional working time) such as increasing tendency of absolute surplus value. Discussion: We suggest that the 12-hour shift system, long working hours, intensified work and poor quantity as well as quality of sleep were the main risk factor for the severe sleepiness among the shift workers in the automobile factory in Korea.

우리나라에서 서로 다른 분모자료가 산업별 규모별 산재 사망별의 계산에 미치는 영향

손미아 서울大學校 保健大學院 國民保健硏究所 2000 國民保健硏究所 硏究論叢 Vol.10 No.1

우리나라에서 서로 다른 분모자료가 산업별 규모별 산재 사망률의 계산에 미치는 영향

손미아 서울大學校保健大學院 2000 國民保健硏究所硏究論叢 Vol.10 No.1

Objective: This paper presents the workplace fatality rates are different according to using different denominators in korea. Method: fatality rates by industry type and factory size among workers in the undustries, which have more than 10 workers in korea between 1995 and 1996, were calculated using different data sources: data from WELCO, Census on basic characteristics of establishments, survey of establishment labour conditions, survey of wage structure, Monthly labour survey. Rates were compared for worker groups defined by industry and factory size. Results: The fatality rates by industry as well as factory type were different according to different sources of denominators, where the proportions of workforce measured according to different industry and factory size differ significantly. This may be because the different data sources have different definition about'the workers'. Some data include temporary workers as well as regularily workers, whereas others only include regularily workers. Especially, as the denominators from WELCO which are used for Government's formal statistics in korea include all temporarily employed. part-time workers, as well as regularily employed workers, these overestimate denominators, especially construction workers, therefore, there looked to be underestimated the fatality rates among construction workers. Conclusion: This suggests that the data sources for denominators for calculation national injury rates needs to be improved and hours worked can be an alternative to overcome the limination of data source of denominators in Korea.

Molecular epidemiology of Korean porcine sapeloviruses

Son, Kyu-Yeol,Kim, Deok-Song,Matthijnssens, Jelle,Kwon, Hyoung-Jun,Park, Jun-Gyu,Hosmillo, Myra,Alfajaro, Mia Madel,Ryu, Eun-Hye,Kim, Ji-Yun,Kang, Mun-Il,Cho, Kyoung-Oh Springer-Verlag 2014 Archives of virology Vol.159 No.5

<P>To evaluate the prevalence and genetic diversity of porcine sapeloviruses (PSVs) in Korea, a total of 100 diarrhea fecal samples from pigs were analyzed by RT-PCR and nested PCR assays with primer pairs specific for the VP1 gene. Overall, 34 % of the diarrhea samples tested positive for PSV, and a high proportion of infections occurred along with a variety of other enteric viruses and bacteria. Genomic and phylogenetic analysis of the VP1 genes revealed pronounced genetic diversities between PSVs from Korean and elsewhere. Our results indicate that PSV infections are very common in Korean pigs with diarrhea. The infecting strains are genetically diverse.</P>

Chemical asphyxia caused by toxic gases generated from rigid polyurethane foams (RPUF) fires

Min-Hui Son,Yuna Kim,Young-Hoon Jo,Mia Kwon 한국분석과학회 2021 학술대회논문집 Vol.2021 No.5

A preliminary study on alcohol kinetics standardization for Korean adult population

Min-Hui Son,Keun-Young Park,Mia Kwon,Hyejin Choi,Dae-Jun Ahn,Se-Jin Oh,Nam-Yee Kim 한국분석과학회 2017 학술대회논문집 Vol.2017 No.5