정신분열병에서 Haloperidol과 Glycine 병용투여의 효과

윤충한,최소현,곽상곤,배석주,강윤형 용인정신의학연구소 1994 용인정신의학보 Vol.1 No.2

당뇨병성 족부병변의 관리

박윤정,윤소영 한국전문물리치료학회 1998 한국전문물리치료학회지 Vol.5 No.2

敎師의 價置觀에 關한 硏究

金鳳韶,李潤樹,安泰潤 경북대학교 교육대학원 1989 논문집 Vol.21 No.-

The purpose of this study was to investigate the attitudes and values of teachers and to contribute to the stability of the further educational scene. The subjects of this study were 1,080 secondary school teachers (715 male teachers, 365 femalse teachers). The analysis of the data was based on the survey method by questionnaire. The main findings of the study are as follows: 1. They respond justly to the fact that the life of teaching profession should be happy and they expect to receive the social treatment, wage increase adn the growth of their students. 2. In response to the view of human beings, most of teachers(75.68%) respond to the fact that the nature of human beings are naturally good. Teachers who respond neither good nor bad are 13.61%, and bad are 10.71%. So, it is anxious that how the teachers who respond to the bad nature guide their students in the field of education. 3. In response to the view of nature, teachers who respond to the fact that they should live in the course of nature are 56.4%, teachers who respond that they should follow the nature obediently are 22.6% and should control the nature are 21.4%. 4. In response to the view of others, most of teachers(91.23%) respond that they should coexist with others. Teachers who respond that they should live for others are 7.55% and who respond that they have no relation with others 1.23%. 5. In view of time, present-oriented are 44.77%, future-oriented 52.69% and past-oriented 2.54%. 6. In view of group, home priority are 46.82%, neighbor 26.03%, nation 17.51% and world priority are 9.64%. 7. In response to the attitudes about value structure, teachers who have priority to the traditional value are 10.78%, who have priority to the new value 17.67% and who take ecletic position 71.55%. 8. In the value of life, teachers who respond to truth are 37.66%, belief 33.71%, goodness 14.42%, saint 9.0%, beauty 3.84%, wealth 1.04% and power (political) 0.31%. 9. In the attitude to the change, teachers who wish the progressive change are 80.7%, who wish the revolution 10.64% and who respond conservatively 8.66%. 10. In response to the personal relationship, teachers who respond that they must cooperate with others are 81.33%, self 32.62%, teacher 24.9%, senior 2.75% and the rest 0.6%. 12. In the field of value formation, teachers who respond to home 38.25%, society 32.57%, school 24.26%, job 4.82% and the rest 0.11%. 13. As a quality the teacher should have, it is ordered as follows; specialty 60.83%, love fore education 59.17%, sincerity 52.78%, responsibility 37.68%, harmonical relationship 34.26%, goal awareness 33.61% and ethics 29.26%. Through the realationship 34.26%, goal responses it is suggested as follows. First, the reality that the living standard of teacher group belongs to the low degree cannot help being a matter of urgency with the improvement of educational condition in the solution of the problem of educational reality. Second, teacher group wants to have the life of teaching profession in pleasant environment and to receive social treatment. Also they want the growth of their students, the stability of life with a wage increase and the opportunity of promotion. Understanding these facts, to satisfy the desirable needs of teacher group political attention for education should be given as soon as possible. Finally, it should be noted that in the attitude about the change of teacher group, most of teachers want the progressive change but in the solution of actual problem more than 10% of the whole teacher group want urgent counterplan.

靑小年交友集團의 類型 構造

李潤樹,金鳳韶,安泰潤 경북대학교 1987 새마을 硏究論叢 Vol.7 No.-

관상동맥 조영술상 정상인 고혈압환자에서 관상동맥 혈류 예비력의 결정인자

고종훈,윤명호,최소연,탁승제 관동대학교 의과대학 의과학연구소 2005 關東醫大學術誌 Vol.9 No.1

Background ; Several studies were reported that reduction of coronary flow reserve(CFR) might lead to myocardial ischemia in the absence of epicardial coronary stenosis. In addition left ventricular hypertrophy might be associated with impairment of coronary flow reserve. The aim of the this study was to assess whether relation exists between CFR and left ventricular mass index(LVMI) and to evaluate the major determinant factors of CFR. Method ; We studied 32 inpatients with hypertension and normal coronary angiogram. Control group consised of 19 subjects(M:F=10:9, mean age 52.6±9.7), group Ⅰ included 14 subjects (LVMI is below 125mg/m2,M:F=6.8 mean age 55.3±14.6) and group Ⅱ consist of 18 subject (LVMI is exceeded 125mg/m2,M:F=5:13 mean age 55.8±9.4). We measured the left ventricular mass(LVM) by M-mode echocardiogram using Devereus and Reichek's method. Left ventricular mass index was calculated as LVM / BSA. We measured average peak velocity at baseline(B) and at adenosine induced hyperemie(H) at the proximal segment of left anteriror descending artery(LAD) using a 0.014 inch 15MHZ doppler wire, CFR was calculated as the hyperemic/baseline(H/B) average peak velocity ratio. Result : 1) There was no significant difference In heart rate, systolic blood pressure or diastolic blood pressure between the two hypertensive groups. 2) The B-APV was significantly increased in hypertensive group compared to the control group(14.4±4.7./21.7.±7.5/23.1±8.1cm/sec p<0.05). 3) CFR was significant reduced in groupⅠand groupⅡ than in the control group (3.2±0.4/2.53±0.6/2.38±0.7 p<0.05). Conclusion ; In hypertensive patients with angiographicaly normal coronary arteries, coronary flow reserve was significantly reduced than normal control group. and CFR was mainly determinant by baseline average peak velocity and not by left ventricular mass index.

당뇨병과 동반된 화농성 간농양의 임상상 및 예후인자

오은숙,강무일,이원영,오기원,임동준,이소영,이정민,고승현,김성래,안유배,손현식,윤건호,차봉연,이광우,손호영,강성구 대한당뇨병학회 2000 임상당뇨병 Vol.1 No.1

연구배경: 감염질환은 혈관질환과 함께 당뇨병의 중요한 사망원인의 하나이며, 혈당조절이 불량할수록 감염 빈도가 증가됨은 잘 알려져 있다. 간농양의 발생이 있어서도 당뇨병은 중요한 기저질환 중의 하나이다. 일반적으로 간농양의 가장 흔한 원인균은 Escherichi coli라고 알려져 있으나, 최근 당뇨병을 가진 간농양 환자에서 Klesiella pneumoniae의 검출이 증가되고 있다. 또 최근 연구에 의하면 K.pneumonie가 간농양의 가장 흔한 원인균이며, K. pneumoniae에 의한 간농양은 K.pneumoniae 이외의 균주에 의한 간농양보다 당뇨병과 밀접히 관련되어 있다고 보고된 바 있다. 이에 저자들은 간농양 환자를 대상으로 당뇨병환자의 빈도를 알아보고, 그 원인균 및 특징을 비당뇨병 환자들의 경우와 비교해 보고자 하였다. 방법: 1992년 1월부터 1999년 6월까지 방사선학적 검사 혹은 수술에 의해 간농양이 확인되거나, 경피적 천자나 수술을 통한 배농액 배양, 혹은 혈액 검사에서 원인균이 증명된 182명의 환자를 대상으로 후향적 임상고찰을 실시하였다. 결과: 화농성 농양을 가진 167명의 환자(남:94명, 여:73명)중 당뇨병을 가진 환자는 54명 (남:30명, 여:24명)으로 32.3%를 차지하였다. 환자의 평균나이는 당뇨군에서 62.1 ± 13.4세, 비당뇨군에서는 55.1 ±15.5세로 당뇨군에서 높았으며(p=0.0021), 남녀간의 평균나이 비교 시 두 군 모두 여성의 나이가 의미있게 높았다. 비당뇨군에 비하여 당뇨군의 경우 저알부민혈증의 빈도와 aspartate transaminase가 증가되어있었다. 원인균주는 K. pneumoniae (당뇨군54%, 비당뇨군 39.1%), E. coli(당뇨군 17.5%, 비당뇨군 18.8%), Pseudomonas aeruginosa, Streptococcus viridans, Enterococcus 순이었으며 두 군간의 의미는 차이는 없었으나 K. pneumoniae의 경우 다른 균종에 비해 단독감염의 빈도가 높았다(82.8%). 사망률은 당뇨군에서 16.7%, 비당뇨군에서 7.1%로 당뇨군에서 의미있게 높았으며(p=0.019), 당뇨군에서의 사망환자는 모두 패혈증이 동반되어 있었다. 당뇨환자의 사망군은 생존군에 비해 당뇨병 이환기간이 길고 혼합감염의 빈도가 높았다(p=0.046). 검사실 소견에서는 총 빌리루빈 및 알카리성 포스파타제의 증가가 관찰되어 있었다. 결론: E. coli가 간농양의 주된 원인균이라는 기존 보고와는 달리 당뇨군과 비당뇨군 모두 K. pneumoniae가 간농양의 주된 원인균이었다. 또한 당뇨 유병기간이 길고 당뇨조절이 불량한 환자에서 혼합감염이며 총 빌리루빈 및 알카리성 포스파타제의 증가등과 같은 위험인자가 존재할 경우 사망률이 증가될 수 있으므로 이들 군에서는 적극적인 치료가 필요할 것으로 사료된다. Background: Liver abscesses are commonly associated with underlying disease, particularly diabete mellitus. The number of the liver abscesses caused by Klebslella pneumoniae in diabetic patient has been increased in Korea nowadays. This study was conducted to clarify the clinical presentation and prognostic factors of pyogenic liver abscesses, especially in diabetic patients and to determine the proportion of K. pneunomiae as a pathogen in liver abscess in Korea. Methods: Medical records of 167 patients treated for pyogenic liver abscess from January, 1992 through June, 1999 were reviewed retrospectively in detail. Major Pathogenic organism, clinical manifestations, prognostic factors, the importance of diabetes mellilus as an underlying disease and its effect on clinical features and prognosis were analyzed. Results: Among 167 cases of pyogenic liver abscess, underlying diabetes mellitus was present in 32.3%. The mean age of patients was 62.7 13.4 years in diabetic liver abscess group and 55.1 15.5 years in non-diabetic liver abscess group. Most liver abscesses were cryptogenic in origin or secondary to the billary tree diseases. The clinical presentations among the two groups were not significantly different. When compared to patients without diabetes, patients with diabetes had significantly higher proportions of hypoalbuminemia and elevated aspartate transaminase level. The most common organism of the pyogenic abscess was K. pneumoniae in both groups. Percutaneous drainage of the abscess with appropriate antibiotics was the most commonly used therapeutic modality in liver abscess. The mortality rate of diabetic liver abscess is 16.1 % and 7.1% in nondiabetic liver abscess. Complications, especially septicemla, were found more frequently in patients with diabetes than in patients without diabetes (64.8% vs 28.3%, septicemia : 31.5% vs 9.7%). The factors influencing mortality in the diabetic liver abscess were disease duration, mixed infection, presence of septicemia, elevated bilirubin and alkaline phosphatase. Conclusions: In contrast to prior report that the E. coli was the most common pathogen in liver abscess, we found that K. pneumoniae was the most common organism cultured in liver abscess. Diabetic patients have more complications and higher mortality than patients without diabetes. Early detection and proper treatment are needed to improve the outcome for diabetic patient with liver abscess.

Mycobacterium bovis Infection at the Interface between Domestic and Wild Animals in Korea

Yoon ra Jang,Yun Ho Jang,So yoon Ryoo,Na rae Kim,Doan Lan Pham,So young Park,Woong seog Song,Suk Chan Jung,Jae Myung Kim 대한수의학회 2013 대한수의학회 학술대회발표집 Vol.2013 No.-

Histologic differentiation between palmoplantar pustulosis and pompholyx

( So Young Yoon ),( Young Woon Park ),( Se Young Na ),( Min Ji Kim ),( Hyun Sun Park ),( Jong Hee Lee ),( So Yun Cho ) 대한피부과학회 2011 초록집 Vol.49 No.20

Eosinophil cationic protein in chronic urticaria (초)

( So Young Yoon ),( Hyuck Hoon Kwon ),( Hye Chan Jeon ),( Mi Ra Choi ),( So Yun Cho ),( Jong Hee Lee ) 대한피부과학회 2010 초록집 Vol.48 No.20

ENT1-mediated AMPK Regulation of Cordyceps militaris on Cell Death in Human Ovarian Cancer

So Young Yoon,Dahye Yun,Dagyeom Kang,Soo Jung Park,Yoon Jung Park 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

Cordyceps militaris extract (CME) has been shown to have anti-cancer effects in various cancer cells, however, the underlying mechanisms remain unclear. CME is enriched for adenosine derivatives including cordycepin. Here, we hypothesized that the adenosine derivatives from CME regulated AMP-activated protein kinase (AMPK) signaling pathway to induce autophagic cell death in ovarian cancer. As results from CRE-based luciferase assay, CME treatment increased cAMP signaling, indicating that its adenosine derivatives exerted as adenosine analogues. CME treatment effectively induced cell death, but the effect on viability was reversed by Equilibrative Nucleoside Transporter protein 1 (ENT1) inhibitor, not by ADORA inhibitors, suggesting that the cell death induction required adenosine derivatives to be transported to the cytosol via ENT1. As a downstream of AMPK signaling, the autophagic cell death was observed with enhanced production of the autophagic vacuoles and LC3II. In conclusion, the data demonstrated that ENT1-mediated transport of adenosine derivative phytochemicals induced autophagic cell death in ovarian cancer cells by regulating AMPK signaling pathway.