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소장내 위석에 의한 장폐쇄증으로 발생한 급성신부전 1례
김승민,남지형,김준섭,이용국,최재혁,강혁주,탁우택,이정호,정호근 東國大學校醫學硏究所 2007 東國醫學 Vol.14 No.1
Gastric bezoars are concretions or hard masses of foreign matter found in the gastrointestinal tract. It may induce many complications including intestinal obstruction. No report has been proposed on a case of prerenal ARF induced by intestinal obstruction by small-bowel bezoar. Therefore, we report a case of the patient with ARF associated with small-bowel bezoar, who initially visited with the symptoms of nausea and frequent vomiting. 위석(bezoar)은 여러 가지 이물 및 내재성물질이 위장관내에서 혼합되어 응고물을 형성한 것을 말하며, 가장 흔한 형태의 합병증으로 장폐쇄증이 올 수 있으나, 그로 인하여 신부전의 양상으로 나타나는 경우는 흔하지 않다. 이에 저자들은 내원 당시의 병력 및 이학적 검사만으로 장폐색의 원인이 위석임을 의심할 수 없었던 비전형적인 소견을 보인 소장내의 위석에 의한 장폐쇄증과 이로 인해 발생한 급성신부전의 예를 경험하였기에 이에 보고하는 바이다.
5-FU 투여후 백서 가슴샘에서 일어나는 형태학적 및 생화학적 변화
손영탁,김선,정옥,한승로,김수일,이영호,김원식 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2
Thymus is a lymphoid organ forming T-cells from hematogenous stem cells. Apoptosis of thymocytes in the cortex of thymus is so rapid that cannot find easily with routine histological techniques. In this experiment, TUNEL immunohistochemistry and TEM were used to detect apoptotic changes after 5-fluorouracil treatment in the thymus of the rat. In addition, SDS-PAGE was carried to reveal protein changes along the apoptotic changes. The results were as follows ; 1. Thymocytes in the cortex were decreased markedly and many apoptotic cells were found in the cortex on DAT 3. 2. Relatively small-sized apoptotic bodies induced by 5-FU were detected on DAT 3 at the cortex, and clustered in partly. 3. On DAT 6, new germinal centers formed in the peripheral cortex, and many apoptotic bodies of various size and shapes were detected in the germinal center. 4. In SDS-PAGE, a protein with molecular weight of 123kDa was increased on DAT 6. According to the above results, it could be concluded that 5-FU acted directly on the thymocytes and induced apoptotic changes on DAT 3. But, on DAT 6, the period of recovery, new germinal centers were formed in the cortex, in which active B cell production to compensate the loss of thymocytes was noticed. To make new T-cells from B-cells and to eliminate unnecessary B-cells, vigorous apoptosis in the germinal centers should occur, and 123kDa proteins which considered as integrins should act as transmembrane signaling molecules in this process.
이동근,조이수,민승기,오승환,정창주,이은택 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.2
Dysfunction of the inferior alveolar nerve indicated by various degree of numbness of the lower lip and chin is one of the few drawbacks of mandibular osteotomy, especially Bilateral Sagittal Split Ramus Osteotomy(BSSRO) and genioplasty. Although it has been recorded throughout the history of this techniques, it is true etiology poorly understood. In this study, 22 consecutive patients under class III malocclusiion impression and undergoing orthognathic surgery(BSSRO only 11 case, BSSRO with genioplasty 11 case) were studied using 4 neurosensory test(static light touch, directional discrimination, two-point discrimination, pin pressure nociception) with post OP 1 week, 2 weeks,4 weeks, 8 weeks, 12 weeks, 24 weeks, On control group, 10 members without trauma and nerve damage history, nerve test was accomplished. We concluded majority of patients return of sensation during post operative 24 weeks. Althought immediate nerve deficit are 92.2%, 97.2% 88.9% these are recovered to 25%, 35.72%, 10.71% at 24 weeks. Nerve recovery rate increased prominently between post 4 weeks and 8 weeks. There is no statistically difference about neurosensory deficit among the chin area. Neurosensory deficit more severe when the BSSRO with genioplasty group than the only BSSRO group. Immediate neurosensory deficit is larger left side than right side but after 6 months, there is no significantly difference between left side and right side. Static light touch and pin pressure nociception are more sensitive method of neurosensory deficit than two point discrimination.
Jeong, Seung Tak,Cho, Song Rae,Lee, Jeong Gu,Kim, Pil Joo,Kim, Gil Won Elsevier 2019 Journal of cleaner production Vol.212 No.-
<P><B>Abstract</B></P> <P>Manure application showed contrasting effects on soil quality and greenhouse gas (GHG) emissions, in particular methane (CH<SUB>4</SUB>) emissions in a rice cropping system. Therefore, to mitigate CH<SUB>4</SUB> emissions, stabilized manure like compost is recommended without considering the additional GHG emissions during the industrial processes and soil organic carbon (SOC) stock changes. To determine the integrated effect of compost utilization on the net global warming potential (GWP) of a rice cropping system, the fluxes of GHGs during the whole process were computed using a life cycle assessment (LCA) method. The model framework was composed of GHG fluxes from two compartments: the industrial activities, and the composting and rice cropping processes. Since manure application can increase SOC stock, the annual SOC stock changes were analyzed by the net ecosystem C budget (NECB). Manure applications significantly increased rice productivity and the net primary production (NPP) as a C input source without difference between fresh and composted manures. NPK+fresh manure application significantly increased CH<SUB>4</SUB> and N<SUB>2</SUB>O emissions by 81% and 37% over the NPK treatment in rice cropping system, respectively, and depleted SOC stock with 1.3 Mg C ha<SUP>−1</SUP> year<SUP>−1</SUP>, due to priming effect. As a result, NPK+fresh manure application increased the net GWP by 80% over the NPK treatment. In comparison, NPK+compost utilization decreased the net GWP by 30% over that of the NPK+fresh manure during the whole process. Manure composting increased the GWP of the industrial processes by 7%, but the 20% reduction of CH<SUB>4</SUB> flux and 0.5 Mg C ha<SUP>−1</SUP> year<SUP>−1</SUP> of SOC stock increase significantly decreased the net GWP during the whole rice cropping process. As a result, the GHG intensity which means the net GWP per gain yield was not different between the NPK+composted manure and the NPK treatments. In conclusion compost application can be a reasonable soil management strategy to reduce GHG emission impact and to increase crop productivity in rice cropping systems.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Compost application was effective to increase rice productivity and soil carbon stock. </LI> <LI> Compost application significantly decreased CH<SUB>4</SUB> emission over the fresh manure in rice field. </LI> <LI> Greenhouse gas emission during composting negligibly contributed to increase the net GWP in the whole rice cropping system. </LI> <LI> Compost utilization decreased the net GWP by 30% over the fresh manure in the whole rice cropping process. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>