http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Synthesis of Dendrimers from Alkyne-focal Dendrons by Oxidative Homo-coupling of Terminal Acetylene
Han, Seung-Choul,Kim, Jong-Sik,Lee, Jae-Wook Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.11
General, fast, and efficient fusion methods for the synthesis of dendrimers with 1,3-diynes at a core were developed. The synthetic strategy was employed the oxidative homo-coupling of terminal alkyne. The oxidative homo-coupling reaction of the alkyne-functionalized Frechet-type dendrons 1-Dm was allowed to provide first through fourth generation dendrimers 2-Gm with 1,3-diynes at core. The fusion of the propargylfunctionalized PAMAM dendrons 3-Dm by homo-coupling of terminal alkyne lead to the formation of symmetric PAMAM dendrimers 4-Gm. Their structure of dendrimers was confirmed by $^1H$ and $^{13}C$ NMR spectroscopy, IR spectroscopy, mass spectrometry, and GPC analysis.
Han, Seung-Choul,Jin, Sung-Ho,Lee, Jae-Wook Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.10
Fr$\acute{e}$chet-type dendritic benzaldehydes were efficiently synthesized using 3,5-dihydroxybenzaldehyde as an aldehyde focal point functionalized unit by adding a generation to the existing dendron or direct oxidation of Fr$\acute{e}$chet-type dendritic benzyl alcohols. These dendritic benzaldehydes were applied for the construction of dendrimers containing secondary amines as connectors via Staudinger/aza-Wittig Reactions with ${\alpha}$,${\alpha}'$,-diazidop-xylene core.
Han, Seung-Choul,Jin, Sung-Ho,Lee, Jae-Wook Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.1
The convergent synthetic strategy for the emissive dendrimers having the chromophore at core via the coppercatalyzed 1,3-dipolar cycloaddition reaction between alkyne and azide was described. 2,7-Diazido-9,9-dioctyl-9H-fluorene, designed to serve as the core in dendrimer, was stitched with the alkyne-functionalized Frechettype and PAMAM dendrons by the click chemistry leading to the formation of the corresponding fluorescent dendrimers in high yields. The preliminary photoluminescence studies indicated that 2,7-diazido-9,9-dioctyl-9H-fluorene showed no fluorescence due to the quenching effect from the electron-rich ${\alpha}$-nitrogen of the azido group but the dendrimers fluoresced due to the elimination of the quenching through the formation of the triazole ring.
Staudinger/Aza-Wittig 반응에 의한 삼발이 핵을 갖는 Frechet-type 덴드리머의 합성
한승철(Seung Choul Han),이재욱(Jae Wook Lee),진성호(Sung Ho Jin) 한국고분자학회 2014 폴리머 Vol.38 No.3
덴드리머의 중심에 삼발이 핵을 갖는 덴드리머의 합성을 위한 효율적인 연결 방법이 개발되었다. 합성전략은알데히드 덴드론과 아자이드기를 갖는 삼발이 핵 사이의 반응을 톨루엔 용매와 triphenylphosphine 존재하에서 진행하는 새로운 클릭화학(Staudinger/aza-Wittig 반응)을 이용하였다. 덴드리머의 삼발이 핵으로 작용할 수 있는 단위체인1,3,5-tris-(3-azido-propoxy)-benzene을 합성하였고, 이 화합물의 아자이드기는 덴드리머의 형성에 이용되었다. 1,3,5-Tris-(3-azido-propoxy)-benzene을 이용하여 알데히드 덴드론과 Staudinger/aza-Wittig 반응을 통해 덴드리머를 합성하였으며, 모든 덴드리머는 높은 수득률로 얻어졌다. Efficient stitching methods for the synthesis of tripodal Frechet-type dendrimers containing secondary amineas a connector were elaborated. The synthetic strategy involved Staudinger/aza-Wittig reactions (new click reaction)between tripodal tris(azides) and aldehyde-dendrons in toluene in the presence of triphenylphosphine and followed by thereduction of imine intermediates. The tripodal core (1,3,5-tris-(3-azido-propoxy)-benzene) was chosen to serve as theazide functionalities for dendrimer growth. 1,3,5-Tris-(3-azido-propoxy)-benzene was stitched with the aldehyde-functionalizedFrechet-type dendrons via Staudinger/aza-Wittig reactions leading to the formation of the correspondingFrechet-type dendrimers in high yields.