사람의 비후성 반흔에서 면역조직화학기법에 의한 형질전환인자 알파와 표피성장인자 발현의 차이에 관한 면역조직화학적 연구

박영란,김현곤,김종중,문정석,송준섭,설경수,정윤영 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.2

Background and Objectives: Transforming growth factor-α (TGF-α) and epidermal growth factor (EGF) are polypeptides which interact with the epidermal growth factor receptor (EGFR) to produce their biological effects. The aim of the present investigation was to elucidate the immunolocalization of TGF-α and EGF in normal human skin, hypertrophic scar with skin graft on soft tissue defect, and postburn hypertrophic scar without graft. Methods: The data presented in this paper focused attention on differences of expression between two kinds of hypertrophic scars in relation to skin graft using immunohistochemistry. Formalin-fixed and paraffin-embedded tissues from 3 normal skin tissues, 3 hypertrophic scars after skin graft and 8 postburn hypertrophic scars without graft were immunolabelled with antibodies directed against TGF-α and EGF. Results: In normal epidermis of skin, strong TGF-α immunoreactivity (IR) was observed in all epidermal layers except the stratum (S.) basale, whereas EGF was immunopositive in a few cells over all epidermal layers. The staining for TGF-α was found in cell membrane, and EGF was seen either diffuse cytoplasmic or peripheral part of cells in normal epidermis. In hypertrophic scar after six months postoperation, TGF-α IR was observed in the upper part of S. spinosum and S. corneum, whereas EGF was diffusely expressed in the S. spinosum, also its intensity was slightly increased compared to normal skin. In hypertrophic scar without skin graft, very strong expression of EGF was detected in the S. spinosum and S. corneum, and intensity of EGF was increased when compared to normal skin and postoperative hypertrophic scar. EGF and TGF-α coexisted in the cells of S. spinosum in normal skin as well as hypertrophic scars. Double-labeled cells were increased in postburn hypertrophic scar compared to normal skin and postoperative hypertrophic scar. In addition, intensity of EGF and TGF-α double IR was the strongest in postburn hypertrophic scar. Conclusion: These results indicate that EGF may have a more complex regulatory role not only in the early stages of wound healing but also in hypertrophic scar.

Catalytic Activity of Y and Fe co-Doped Srtio_3 Perovskites for Methane Oxidation

Jong Seol Yoon,Young Han Kim,Mi Jung Ji,Byung Hyun Choi,황해진 대한금속·재료학회 2011 ELECTRONIC MATERIALS LETTERS Vol.7 No.3

Y and Fe co-doped SrTiO_3 powder with a phase-pure perovskite structure were synthesized by solid state reaction (SSR) and the Pechini method. The catalytic activity of Y_(0.08)Sr_(0.92)Fe_xTi_(1-x)O_3 (x = 0.1, 0.2, 0.3, and 0.4) for the methane oxidation reaction was evaluated in terms of the iron content in the perovskite lattice. When the CH4/O2 ratio was 0.25, the total oxidation of methane was predominant. Methane oxidation started at 450ºC and increased with increasing temperature. The methane conversion rate strongly depended on the iron content. With higher iron content, the methane conversion rate was accordingly enhanced. This phenomenon may be attributed to the presence of oxygen vacancies in the perovskite lattice. At a CH4/O2 ratio=2,a partial oxidation reaction occurred at temperature above 750°C.

Fabrication of an ionic/electronic nanocomposite for a high flux oxygen ion transport membrane

Jong Seol Yoon,Young Chul Cha,Ji-Woong Moon,황해진 한양대학교 세라믹연구소 2008 Journal of Ceramic Processing Research Vol.9 No.4

Ce0.9Gd0.1O2−δ (GDC)/Ba0.5Sr0.5Co0.8Fe0.2O3−δ (BSCF) nanocomposites were fabricated by a conventional power processing technique from a commercially available GDC and a BSCF powder prepared in-house. The BSCF was synthesized via the glycine-nitrate process (GNP). XRD analysis indicated that the GDC was found to be compatible with the BSCF at a sintering temperature of 1150 oC. Dense GDC/BSCF nanocomposites having a relative density above 95% could be obtained when a green compact of BSCF and GDC powder mixture was sintered at 1150 oC for 5 h. GDC particles were found to be homogeneously dispersed in the BSCF matrix and some smaller GDC particles less than a few hundred nm in size were incorporated inside the large BSCF grains. The grain size of the BSCF was decreased by an addition of the GDC, suggesting the GDC can hinder the grain growth of the BSCF. Ce0.9Gd0.1O2−δ (GDC)/Ba0.5Sr0.5Co0.8Fe0.2O3−δ (BSCF) nanocomposites were fabricated by a conventional power processing technique from a commercially available GDC and a BSCF powder prepared in-house. The BSCF was synthesized via the glycine-nitrate process (GNP). XRD analysis indicated that the GDC was found to be compatible with the BSCF at a sintering temperature of 1150 oC. Dense GDC/BSCF nanocomposites having a relative density above 95% could be obtained when a green compact of BSCF and GDC powder mixture was sintered at 1150 oC for 5 h. GDC particles were found to be homogeneously dispersed in the BSCF matrix and some smaller GDC particles less than a few hundred nm in size were incorporated inside the large BSCF grains. The grain size of the BSCF was decreased by an addition of the GDC, suggesting the GDC can hinder the grain growth of the BSCF.

슈퍼 태풍 하이옌(Haiyan) 내습에 따른 필리핀 해역에서의 폭풍해일 및 파랑 수치 모의

윤종주(Jong-Joo Yoon),이종찬(Jong-Chan Lee),심재설(Jae-Seol Shim),박광순(Kwang-Soon Park),전인식(Insik Chun) 한국연안방재학회 2014 한국연안방재학회지 Vol.1 No.3

Super typhoon Haiyan made landfall in the Leyte island, Philippines and devastated the areas located near the typhoon passage on 8 November 2013. Its maximum sustained 1 minute surface wind speed was reported about 315 km/h, which is recorded to strongest Category 5 hurricane and super typhoon. This was one of the strongest historical storm event in the world, killing at least 6,268 people in the Philippines. Large loss of life was occurred from inundation of low-lying areas by storm surge and waves. In particular, there was widespread devastation by a high storm surge in Tacloban city. In this study, the impacts of storm surge and waves were investigated after numerical simulation using the unstructured grid model, FVCOM and SWAVE. The simulated results reasonably represented reported surge height. Estimated surge and wave height were shown approximately 3.9 m and 1.6 m in the Tacloban city. However, further detail model validation is still needed using additional observation data.

군 비행장의 갈등관리 요인 분석

윤종설(Yoon Jong Seol) 한국정책개발학회 2010 정책개발연구 Vol.10 No.2

이 논문은 지난 수십년 동안 군사시설보호구역으로 지정된 수원비행장 주변의 고도제한규제, 건축제한규제로 인한 다양한 사회갈등 유발에 따른 효과적인 대책마련 위해 갈등관리 요인분석을 실시하였다. 논문의 분석기준이 될 갈등관리 성공요인을 도출하여, 도출된 성공요인(합의안의 정당성 요인, 갈등관리과정의 효율성 요인, 갈등당사자의 만족도 요인, 이해관계자 간 관계성 요인, 합의안의 지속성 요인, 그리고 합의안의 합리성 요인)을 주요 분석요인으로 하여 수원비행장 소음피해규제와 비행안전규제의 현황과 실태에 적용ㆍ분석하였다. The objective of this paper is to suggest effective resolution to the conflicts over Suwon Airport regulations. The airport has been protected as a military facility for the last few decades with regulations such as altitude and construction on the surrounding areas. This has caused various social conflicts. To come up with effective resolution, the paper first identifies conflict management success factors which are justification of the agreement, efficiency of conflict management process, satisfaction of the stake holders, relationship between the stake holders, continuity of the agreement, and rationality of the agreement. These factors are then applied in analyzing the current status and impact of Suwon Airport noise pollution and flight safety regulations.

고관절 이형성증에서 Center Edge 각에 따른 응력분포와 비구회전 절골술의 생역학적 영향

윤택림(Taek Rim Yoon),노성만(Sung Man Rowe),설종윤(Jong Yoon Seol),조규종(Kyu Jong Cho),김규하(Gyu Ha Kim),반제삼(Je Sam Ban) 대한정형외과학회 2003 대한정형외과학회지 Vol.38 No.2

Postoperative Complications and Cost-effectiveness of Simultaneous and Staged Bilateral Total Hip Arthroplasty Using a Modified Minimally Invasive Two-incision Technique

( Jong Hwan Seol ),( Kyung Soon Park ),( Taek Rim Yoon ) 대한고관절학회 2015 Hip and Pelvis Vol.27 No.2

Purpose: To compare the postoperative complications and cost-effectiveness of simultaneous and staged bilateral total hip arthroplasty (THA), using a minimally invasive two-incision technique. Materials and Methods: All 206 patients who underwent simultaneous or staged bilateral THA using a modified, minimally invasive two-incision between January 2004 and November 2009 were registered and divided into a simultaneous bilateral THA group (group A, 147 patients) and staged bilateral THA group (group B: 59 patients). Staged THA was performed on group B with interval of at least 2 months between the initial and second surgery. Clinical evaluations, amount of blood loss, need for transfusion, complications and costeffectiveness were compared. Results: Perioperative morbidity rates were similar in the two groups (P=0.546) and overall complications were not significant between the groups. Average length of hospital stay was significantly shorter in group A than in group B (average 14.6 days vs. 25.3 days; P<0.001). Total medical cost was significantly higher in group B than in group A (average 9,236 US dollars vs. 11,163 US dollars). Patients in group A required more blood transfusions than those in group B (3.02 vs. 1.90 units; P=0.003), although blood loss in the two groups were similar (892 vs. 917 ml P=0.613). Conclusion: Comparison of intra- and postoperative complications support the conclusion that simultaneous bilateral THA compares favorably with staged THA in terms of outcomes, complications and cost-effectiveness.

Factors associated with performance of infection control among some physical therapists

Seol, Yoon-Yee,Han, Mi Ah,Park, Jong,Ryu, So Yeon 대한물리치료학회 2016 대한물리치료학회지 Vol.28 No.2

Purpose: Infection management is important for physical therapists in order to protect patients and themselves since they often provide patient care and have physical contact with patients. This study examined the performance of infection control and associated factors among physical therapists. Methods: The study subjects were 174 physical therapists working in the G metropolitan city. The performance of infection control according to general characteristics, job-related characteristics, and infection-related characteristics were compared using t-test and ANOVA. Associations between awareness and performance of infection control were tested by correlation. Finally, multiple linear regression analyses were performed to examine the factors associated with performance of infection control. Results: Overall performance scores for personal and therapy room were $87.47{\pm}11.70$ and $70.08{\pm}13.68$, respectively. Both personal and therapy room infection control were lower for the degree of performance than the degree of awareness. In multiple linear regression analysis, the degree of performance at a personal level was related to current smoking status, type of charge therapy, supply of protection equipment, and awareness of personal infection control. The degree of performance of therapy room was related to injury experience in the workplace, supply of protection equipment, and awareness of therapy room infection control. Conclusion: Performance of therapy room infection control was lower than that of personal infection control. The performance was associated with the supply of protection equipment and awareness. Therefore, the degree of performance for infection control will be increased with proper supply of protection equipment in the hospital and increase the degree of awareness with adequate prevention education.

Estimation of storm surge inundation and hazard mapping for the southern coast of Korea

Yoon, Jong-Joo,Shim, Jae-Seol BioOne (Coastal Education and Research Foundation) 2013 JOURNAL OF COASTAL RESEARCH Vol.65 No.-

<P>The coastal area of Korea is damaged by the approach of typhoons every year. The most serious inundation damage, with loss of lives and properties, was caused by typhoon Maemi in September 2003. After this event, there has been increased interest in addressing these coastal zone problems. It is therefore desirable to accurately forecast the storm surge height. In this study, using a numerical finite-volume coastal ocean model (FVCOM), a storm surge was simulated to investigate its inundation characteristics for the coastal area at Masan, Yeosu and Busan cities on the southern coast of Korea. In the model, a moving boundary condition (wet-dry treatment) was applied to examine inundation propagation by storm surge. The model grids were extended up through the lowland area by applying the DEM, made by precisely combining the airborne-LiDAR survey and bathymetry data. A minimum 30 m resolution unstructured triangular mesh was applied to calculate the storm surge and inland inundation. Simulated inundation range and depth were compared with the inundation map made from field measurements after the typhoon event. The results of inundation simulations in this study show good correspondence with not only the observed inundation area but also inundation depth. We also estimated the special inundation level distributions for each return period. The numerical model system adopted in this study could be a useful tool for analyzing storm surges, and for predicting coastal inundation. In addition, it is necessary for preparing detailed evacuation plans, including hazard maps for associated storm surge inundation problems.</P>

Factors associated with performance of infection control among some physical therapists

( Yoon-yee Seol ),( Mi Ah Han ),( Jong Park ),( So Yeon Ryu ) 대한물리치료학회 2016 대한물리치료학회지 Vol.28 No.2

Purpose: Infection management is important for physical therapists in order to protect patients and themselves since they often provide patient care and have physical contact with patients. This study examined the performance of infection control and associated factors among physical therapists. Methods: The study subjects were 174 physical therapists working in the G metropolitan city. The performance of infection control according to general characteristics, job-related characteristics, and infection-related characteristics were compared using t-test and ANOVA. Associations between awareness and performance of infection control were tested by correlation. Finally, multiple linear regression analyses were performed to examine the factors associated with performance of infection control. Results: Overall performance scores for personal and therapy room were 87.47±11.70 and 70.08±13.68, respectively. Both personal and therapy room infection control were lower for the degree of performance than the degree of awareness. In multiple linear regression analysis, the degree of performance at a personal level was related to current smoking status, type of charge therapy, supply of protection equipment, and awareness of personal infection control. The degree of performance of therapy room was related to injury experience in the workplace, supply of protection equipment, and awareness of therapy room infection control. Conclusion: Performance of therapy room infection control was lower than that of personal infection control. The performance was associated with the supply of protection equipment and awareness. Therefore, the degree of performance for infection control will be increased with proper supply of protection equipment in the hospital and increase the degree of awareness with adequate prevention edu-cation.