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Sanjay Bansal,Sandeep Garg,Rajat Harvinder Dang,Rasleen Kaur Pahuja 대한치과보철학회 2013 The Journal of Advanced Prosthodontics Vol.5 No.3
PURPOSE This study was aimed to determine the effect of two chemically distinct denture cleansers and water on the surface hardness of acrylic and silicone based soft denture liners at various time intervals. MATERIALS AND METHODS Two commonly used commercial resilient liner material were selected based on their chemical composition (silicone- and acrylic-based soft liners) for this investigation. 120 cylindrical specimens were made of 15 mm × 10 mm dimensions (according to ASTM: D-2240-64T) in a custom made metal mold. All specimens were stored in artificial saliva throughout the study. Forty specimens were cleansed daily in 0.5% sodium hypochlorite solution; forty were cleansed in sodium perborate and remaining forty specimens were daily rinsed in water. Testing was done at 1 week, 1 month, 3 months and 6 months for surface hardness using a Shore A Durometer. A mean of 3 reading for each sample was subjected to one-way ANOVA, Post Hoc test and pair-t test for statistical analysis. P values of less than 0.05 were taken as statistically significant. RESULTS Surface hardness of all the samples was significantly higher after a period of 6 months irrespective of the cleansing treatment. Minor changes were observed between control, sodium hypochlorite and sodium perborate groups with time. Greater change was observed in surface hardness of acrylic-based soft denture liners as compared to silicone-based soft liners for all groups, as time progressed. CONCLUSION Silicone-based soft denture liners performed significantly better in all cleansing treatments than acrylic-based soft denture liners.
Cogging Torque Minimization of PMBLDC Motor for Application in Battery Electric Vehicle
Bansal Rupam,Marwaha Sanjay,Verma Chaman 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.3
Since the beginning, researchers have focused globally on the automotive industry, which recently yielded a notable increase in the development of electric vehicles. The cogging torque of the motor is the leading cause of acoustic noise and vibration. Therefore, this paper aims to reduce the cogging torque of Brushless DC motors in electric vehicles. The power rating of the two-wheeler battery electric vehicle is determined with kinematic dynamic equations. The choice of material and the combination of pole slots impact the vehicle’s overall performance, particularly in raising the average torque of the motor. Finite element based Ansys Maxwell electromagnetic field simulation software has been used to design and analyze the electric and magnetic field parameters of BLDC motor using several rotor poles embrace factor values. The findings of this study are expected to reduce vibration and noise in electric vehicles with increased average torque.
High Rates of SVR12 in Adolescents Treated with the Combination of Ledipasvir/Sofosbuvir
( Kathleen Schwarz ),( Karen F. Murray ),( Philip Rosenthal ),( Sanjay Bansal ),( Chuan-hao Lin ),( Sooji Lee ),( Liyun Ni ),( Bittoo Kanwar ),( Jenna Fraser ),( Polina German ),( Diana M. Brainard ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: Although direct acting antivirals have transformed HCV treatment of adults, the standard of care for adolescents and younger children with GT1 HCV is still limited to treatment with pegylated interferon+ribavirin for 48 weeks. The aim of this study was to evaluate the safety, efficacy and pharmacokinetics of the fixed dose single tablet regimen, ledipasvir/sofosbuvir (LDV/SOF), administered for 12weeks in GT1 HCV-infected adolescent patients. Methods: Treatment-naive and treatment-experienced adolescent patients aged 12 to less than 18 years old with chronic GT1 HCV were enrolled into this open-label ongoing study to receive 12 weeks of treatment with LDV/SOF 90mg/400 mg once daily. The primary efficacy endpoint is SVR12 (HCV RNA<lower limit of quantitation). Safety is assessed by clinical evaluation and laboratory monitoring. Intensive pharmacokinetic (PK) sampling was done on Day 10 in the first 10 patients (PK lead-in) to confirm the appropriateness of the adult dose in the adolescent population. Results: 100 GT1 patients have been enrolled and treated. The majority are GT1a (81%), female (63%), white (90%), treatment-naive (80%), and vertically infected (84%). The mean age is 15 (range 12-17) years. In the PK lead-in, administration of 1 tablet daily of LDV/SOF provided comparable plasma exposures of LDV, SOF, and GS-331007 (SOF primary metabolite) to those observed in adults. SVR12 rate was 97% (97/100). 3 patients were lost to follow-up. No serious adverse events (AEs) have been reported. AEs are generally mild in severity and grade 3/4 laboratory abnormalities have been infrequent and transient. Conclusions: The 12-week regimen of LDV/SOF 90mg/400 mg has resulted in high SVR rates and is well-tolerated. This regimen provides a safe and effective therapy for adolescents with GT1 HCV infection. Further evaluation is ongoing in children aged 3-11 years old.
Pahuja, Rasleen Kaur,Garg, Sandeep,Bansal, Sanjay,Dang, Rajat Harvinder The Korean Academy of Prosthodonitics 2013 The Journal of Advanced Prosthodontics Vol.5 No.3
PURPOSE. This study was aimed to determine the effect of two chemically distinct denture cleansers and water on the surface hardness of acrylic and silicone based soft denture liners at various time intervals. MATERIALS AND METHODS. Two commonly used commercial resilient liner material were selected based on their chemical composition (silicone- and acrylic-based soft liners) for this investigation. 120 cylindrical specimens were made of $15mm{\times}10mm$ dimensions (according to ASTM: D-2240-64T) in a custom made metal mold. All specimens were stored in artificial saliva throughout the study. Forty specimens were cleansed daily in 0.5% sodium hypochlorite solution; forty were cleansed in sodium perborate and remaining forty specimens were daily rinsed in water. Testing was done at 1 week, 1 month, 3 months and 6 months for surface hardness using a Shore A Durometer. A mean of 3 reading for each sample was subjected to one-way ANOVA, Post Hoc test and pair-t test for statistical analysis. P values of less than 0.05 were taken as statistically significant. RESULTS. Surface hardness of all the samples was significantly higher after a period of 6 months irrespective of the cleansing treatment. Minor changes were observed between control, sodium hypochlorite and sodium perborate groups with time. Greater change was observed in surface hardness of acrylic-based soft denture liners as compared to silicone-based soft liners for all groups, as time progressed. CONCLUSION. Silicone-based soft denture liners performed significantly better in all cleansing treatments than acrylic-based soft denture liners.
Sameet Tariq Patel,Anuraag Jena,Sanjay Chandnani,Shubham Jain,Pankaj Nawghare,Saurabh Bansal,Harsh Gandhi,Rishikesh Malokar,Jay Chudasama,Prasanta Debnath,Seemily Kahmei,Rima Kamat,Sangeeta Kini,Qais 대한장연구학회 2024 Intestinal Research Vol.22 No.3
Background/Aims: Patients of ulcerative colitis (UC) on follow-up are routinely evaluated by sigmoidoscopy. There is no prospective literature to support this practice. We assessed agreement between sigmoidoscopy and colonoscopy prospectively in patients with disease extent beyond the sigmoid colon. Methods: We conducted a prospective observational study at a tertiary care institute for agreement between sigmoidoscopy and colonoscopy. We assessed endoscopic activity using the Mayo Endoscopic Score (MES) and Ulcerative Colitis Endoscopic Index of Severity (UCEIS) and histological activity using the Nancy Index (NI), Robarts Histopathology Index (RHI), and Simplified Geboes Score (SGS). Results: Sigmoidoscopy showed a strong agreement with colonoscopy for MES and UCEIS with a kappa (κ) of 0.96 and 0.94 respectively. The misclassification rate for MES and UCEIS was 3% and 5% respectively. Sigmoidoscopy showed perfect agreement (κ = 1.00) with colonoscopy for assessment of the presence of endoscopic activity in the colon using MES ≥ 1 as activity criteria and strong agreement (κ = 0.93) using MES > 1 as activity criteria. Sigmoidoscopy showed strong agreement with colonoscopy for assessment of the presence of endoscopic activity using UCEIS (κ = 0.92). Strong agreement was observed between sigmoidoscopy and colonoscopy using NI (κ = 0.86), RHI (κ = 1.00), and SGS (κ = 0.92) for the detection of histological activity. The misclassification rate for the detection of histological activity was 2%, 0%, and 1% for NI, RHI, and SGS respectively. Conclusions: Sigmoidoscopy showed strong agreement with colonoscopy for endoscopic and histologic disease activity. Sigmoidoscopy is adequate for assessment of disease activity in patients with UC during follow-up evaluation.